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21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessPersonnel management. Employment management

The effect of creativity and innovative behavior on competitive advantage in womenpreneur

Retno P. Setyaningrum, Muafi Muafi · 2022 · SA Journal of Human Resource Management

Orientation: Indonesia is currently in the industrial revolution 4.0 and 5.0. Woman entrepreneurs must be able to increase creativity, innovative behaviour and trust in digital technology to have sustainable competitive advantage for their firm. Research purpose: This study aimed to examine and analyse the impact of creativity and innovative behaviour on competitive advantage mediated by trust in digital technology for women entrepreneurs. Motivation for the study: The literature of creativity, innovative behaviour, trust in digital technology and competitive advantage is still limited in wome

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Negative / Null Result ReportOpen accessNutrition. Foods and food supply

Effects of N-acetylcysteine on aging cell and obesity complications in obese adults: a randomized, double-blind clinical trial

Mohammad Hassan Sohouli, Ghazaleh Eslamian, Nasser Malekpour Alamdari et al. · 2023 · Frontiers in Nutrition

BackgroundWe decided to conduct this study with the aim of investigating the effects of N-Acetylcysteine (NAC) on obesity complications and senescence of visceral adipose tissue in obese adults.Methods and analysisThe present study was conducted as a randomized clinical trial (RCT) (Clinical trial registry number: IRCT20220727055563N1) on 40 obese adults candidates for bariatric surgery, who were randomly assigned to receive 600 mg of NAC (n = 20) or placebo as a control (n = 20) for 4 weeks. During bariatric surgery, visceral adipose tissue was used to examine gene expression and senescence c

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Negative / Null Result ReportOpen accessOphthalmology

Effects of preoperative doses of betamethasone acetate 0.1% on dry eye control after cataract surgery

Saeed Shokoohi-Rad, Seyedeh Zeinab Hashemi Javaheri, Fatemeh Zare Malekabad et al. · 2020 · Indian Journal of Ophthalmology

Purpose: The aim of the present study was to compare the effects of the preoperative doses of betamethasone acetate 0.1% and placebo on controlling dry eye after cataract surgery. Methods: This randomized triple-blind clinical trial was conducted on 62 patients. For the purpose of the study, the participants were assigned into two groups of betamethasone (n = 28) and placebo (n = 34). The groups were administered with drops A or B three days before the operation, four times a day. These drops contained either betamethasone 0.1% or normal saline (placebo). Postoperative follow-up was performed

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Negative / Null Result ReportOpen accessFood processing and manufacture

Optimize the Instantaneous High Temperature Sterilization Process of Ilex kudingcha Based on Multiple Index Analysis

Ting ZHANG, Lianqing JIAO, Rongrong LIU et al. · 2023 · Shipin gongye ke-ji

To optimize the instantaneous high-temperature sterilization process parameters of Ilex kudingcha based on multiple indicators. The process parameters of instantaneous high-temperature sterilization of Ilex kudingcha were optimized by using the orthogonal design multi-index comprehensive weighted scoring method. Sterilization temperature, sterilization time, and particle size of herbs were used as the investigating factors, the sterilization rate, IC50 value of antioxidant activity of 1,1-diphenyl-2-picrylhydrazyl (DPPH·), and polyphenolic content were used as indicators, visual and ANOVA resu

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Negative / Null Result ReportOpen accessScience

Influence of processing and matrix parameters on the manufacturing of unidirectional flax/polypropylene composites

Agnès Mattlet, Olivier Sicot, Laetitia Van Schoors et al. · 2023 · SN Applied Sciences

Abstract The manufacturing by thermocompression of flax fiber composites requires a good understanding of process parameters. This work focuses on the influence of key parameters in the manufacture of quality unidirectional flax/polypropylene composites by thermocompression. To this effect, a number of matrix and process parameters have been studied and ranked according to their influence on composite morphology and tensile properties. Among tested parameters, process time and temperature tend to decrease tensile strength as they increased from 3 to 11 min and from 180 to 200 °C. As a result,

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Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system

The effect of subchronic cigarette smoke exposure on oxidative stress parameters and endothelial nitric oxide synthase in a rat aorta

Meity Ardiana, Budi Pikir, Anwar Santoso et al. · 2021 · ARYA Atherosclerosis

BACKGROUND: The compounds in cigarette smoke are believed to cause oxidative stress, leading to endothelial dysfunction. Understanding the mechanism of endothelial dysfunction due to cigarette smoke is useful for the development of early and preventive therapy for cardiovascular diseases (CVDs) with smoking risk factors.METHODS: In this experimental study, a posttest-only control group design was used. 20 Wistar rats were divided into two groups: a smoking group (exposed to 40 cigarettes per day for 4 weeks) and a control group. After the exposure, the animals were sacrificed and aortas were r

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Negative / Null Result ReportOpen accessMedicine

HBV-related hepatocellular carcinoma susceptibility gene KIF1B is not associated with development of chronic hepatitis B.

Rong Zhong, Yao Tian, Li Liu et al. · 2012 · PLoS ONE

A recent genome-wide association study has identified a new susceptibility locus, kinesin family member 1B gene (KIF1B), strongly associated with progression from chronic hepatitis B (CHB) to hepatitis B virus-related hepatocellular carcinoma (HCC) in Chinese population, this study was carried out to explore the role of the genetic variants in KIF1B in the development of chronic hepatitis B.Three KIF1B polymorphisms (rs8019, rs17401924, and rs17401966) were selected and genotyped in 473 CHB patients and 580 controls with no history of CHB. Odds ratios (ORs) and 95% confidence intervals (CIs) w

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Negative / Null Result ReportOpen accessMedicine

Effects of hot air treatment and chitosan coating on citric acid metabolism in ponkan fruit during cold storage.

Yang Gao, Chaonan Kan, Chunpeng Wan et al. · 2018 · PLoS ONE

In citrus fruit, citric acid is the predominant organic acid which influence fruit taste, flavor and quality. The effect of hot air treatment (HAT 40°C, 48 h) and 1.0% chitosan coating on the change of organic acids and the related gene expression of citric acid synthesis and degradation in ponkan (Citrus reticulata Blanco) fruit during cold storage have been studied. The results showed that citric acid was the main organic acid in fruit, the trend change of citric acid content was consistent with total organic acids and titratable acidity (TA) content, which decreased with the prolongation of

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Negative / Null Result ReportOpen accessZoology

Efects of Usnic, Barbatic and Fumarprotocetraric acids on Survival of Nasutitermes corniger (Isoptera: Termitidae: Nasutitermitinae)

Monica C B Martins, Rosineide Silva Lopes, Patricia Silva Barbosa et al. · 2018 · Sociobiology

Lichens (Algal-Fungal association) synthesize unique chemical substances with different biological activities. Three pure lichen compounds were assayed to evaluate their potential insecticidal activity against the termite Nasutitermes corniger on Petri dishes. Usnic, fumarprotocetraric and barbatic acids were isolated and purified from the lichens Cladonia substellata, C. verticillaris and Cladia aggregata, respectively, using thin-layer and high-performance liquid chromatography for attesting their purity. Nuclear proton magnetic resonance and infrared spectrophotometry was used for their che

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Negative / Null Result ReportOpen accessMicrobiology

The Effect of Dexamethasone-Mediated Atrophy on Mitochondrial Function and BCAA Metabolism During Insulin Resistance in C2C12 Myotubes

Kayla J. Ragland, Kipton B. Travis, Emmalie R. Spry et al. · 2025 · Metabolites

Background : Muscle loss during sarcopenia and atrophy is also commonly associated with age-related insulin resistance. Interestingly, branched-chain amino acids (BCAA) which are known for stimulating muscle protein synthesis are commonly elevated during insulin resistance and sarcopenic obesity. Objectives : This study investigated the effects of the interplay between atrophy and insulin resistance on insulin sensitivity, mitochondrial metabolism, and BCAA catabolic capacity in a myotube model of skeletal muscle insulin resistance. Methods : C2C12 myotubes were treated with dexamethasone to i

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Negative / Null Result ReportOpen accessBusiness

Pengaruh Kualitas Layanan, Ketersediaan Produk Wisata, Citra Destinasi Terhadap Kepuasan dan Loyalitas Destinasi Kampung Karuhun Sumedang

Rina Trisnawati, Nono Wibisono · 2022 · Jurnal Bisnis dan Kewirausahaan

Sumedang Regency is an area that has various types of tourist attractions but tourist visits to Sumedang fluctuate every year. One of the attractions in Sumedang is Kampung Karuhun which still needs improvement in several aspects. This study aims to identify the influence of the relationship of service quality, tourism product availability, destination image, consumer satisfaction and destination loyalty in Kampung Karuhun Sumedang. The research method used is a quantitative approach using a survey tool in the form of a questionnaire. This study collected data as many as 355 respondents. The a

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Negative / Null Result ReportOpen accessEducation

An evaluation of teachers' performance on gender and work experience with the charlotte danielson evaluation model

Lovely Ezverenzha Lelatobur, Daniel Herman Ferdy Manongga, Ade Iriani · 2024 · Jurnal Penelitian dan Evaluasi Pendidikan

The performance teachers in the preliminary study still use teacher-centred methods, both teachers who have received certification and those who have not. On the other hand, the evaluation in schools is still on teacher performance related to learning design and the learning process in the class. Therefore, social, personality and professional competencies are still less reviewed. The purpose of this study is to evaluate teachers' performance based on their gender and work experience in public senior high schools in Maluku Barat Daya (MBD) district. Four main components were used to assess tea

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Negative / Null Result ReportOpen accessAgriculture

Impact of irrigation during flowering and fruit growth on fruit yield and quality of the cactus Opuntia spp.

Mohamed ARBA, André FALISSE, Redouane CHOUKR-ALLAH et al. · 2021 · Acta Agriculturae Slovenica

Most plantations of cactus pear are not irrigated in Morocco and fruits are tiny. The impacts of irrigation during flowering (FLO) and fruit growth (FRG) on fruit yield and quality were monitored along two years on three varieties of cactus pear. In 2011, irrigation treatments were: T1 (0 mm), T2 (30 mm during FLO and 30 mm during FRG) and T3 (30 mm during FRG only). In 2012, irrigation treatments increased to 60 mm during FLO and FRG. The irrigation treatments were applied in 8 (T3) or 16 (T2) watering, once every three days. Interactions between varieties and treatments were significant for

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Negative / Null Result ReportOpen accessAnimal culture

Early-age feed restriction affects viability and gene expression of satellite cells isolated from the gastrocnemius muscle of broiler chicks

Li Yue, Yang Xiaojing, Ni Yingdong et al. · 2012 · Journal of Animal Science and Biotechnology

Abstract Background Muscle growth depends on the fusion of proliferate satellite cells to existing myofibers. We reported previously that 0–14 day intermittent feeding led to persistent retardation in myofiber hypertrophy. However, how satellite cells respond to such nutritional insult has not been adequately elucidated. Results One-day-old broiler chicks were allocated to control (Con, ad libitum feeding), intermittent feeding (IF, feed provided on alternate days) and re-feeding (RF, 2 days ad libitum feeding after 12 days of intermittent feeding) groups. Chickens were killed on Day 15 and sa

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Negative / Null Result ReportOpen accessAgriculture (General)

Water absorbent polymer in sugarcane crop Polímeros hidroabsorventes em cultura canavieira

Tadeu A. Marques, Patricia A. A. Marques, Marcos W. Suriani et al. · 2013 · Engenharia Agrícola

The water absorbent polymer effect on vegetative growth and production of Theoretical Recovery Sugar (TRS) of sugarcane cv. RB 86 7515 was evaluated on two field tests installed in randomized blocks, with four treatments and five repetitions. The polymer doses were 0; 4; 8 and 12 g m-1 of furrow (test 1) and 0; 1.4; 2.8 and 4.2 g m-1 of furrow (test 2). Test 1 (dec/2007 to may/2009) was implanted in a Distroferric Red Argisol soil in Presidente Prudente - State of São Paulo (SP), Brazil; and the test 2 (Aug/2008 to Aug/2009) was implanted in a Red Yellow Argisol soil in Lucélia - State of São

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Negative / Null Result ReportOpen accessBiochemistry

Nutrition status of greenhouse tomato grown in intert media. Part I. Macroelements

Piotr Chohura, Andrzej Komosa · 2003 · Acta Scientiarum Polonorum: Hortorum Cultus

In the experiments carried out in the years 1998-1999 the effect of inert media and fertilization levels on the nutrition status of greenhouse tomato cv. ‘Maeva F1’ was investigated. Two feeding solutions were used: I, containing (in mg dm-3): N-NO3 – 189, P – 62, K – 371, Ca – 190, Mg – 49, Fe – 0.84, Mn – 1.87, B – 0.32, Zn – 2.01, Cu – 0.048, Mo – 0.048, pH 5.5, EC – 3.2 mS cm-1; and solution II with the concentration increased by 20%, and three inert media: rockwool (Grodan), polyurethane foam (Inert) and expanded clay (granulation 4–8 mm). In the index parts of the tomato (9–10 leaf from

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Negative / Null Result ReportOpen accessGynecology and obstetrics

The effect of laser-assisted hatching on clinical outcomes of frozen-thawed embryo transfer at different embryo ages

Min-Min Ou, Bi-Yun Liao, Xing-Hong Chen et al. · 2026 · European Journal of Obstetrics & Gynecology and Reproductive Biology: X

Objective: To investigate the impact of laser-assisted hatching (LAH) on clinical outcomes in patients undergoing frozen-thawed embryo transfer (FET) cycles with embryos at different developmental stages. Methods: We conducted a retrospective analysis of 2208 patients who underwent vitrification-thawed FET at our reproductive center between October 2018 and June 2024, with some patients contributing multiple cycles. Patients were stratified by embryonic developmental stage into cleavage-stage FET (n = 793) and blastocyst-stage FET (n = 1415) groups. Each group was further subdivided based on p

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Negative / Null Result ReportOpen accessAgriculture

PENGARUH DOSIS PUPUK ORGANIK BIO-SLURRY CAIR DAN WAKTU APLIKASI TERHADAP PERTUMBUHAN DAN HASIL TANAMAN JAGUNG (Zea mays L.)

Akari Edy, Resti Puspa Kartika Sari, Hidayat Pujisiswanto · 2021 · Jurnal Agrotropika

Lampung is a center for maize and cattle production. This study aims to determine (1) the dosage of liquid bio-slurry fertilizer which is effective in increasing the growth and yield of maize, (2) the correct split application time of liquid bio-slurry, (3) the interaction between the dose of liquid bio-slurry fertilizer and time of split application on the growth and yield of maize. The research was conducted in Fajar Baru Village, Jati Agung District, South Lampung Regency. The study used a randomized block design (RBD) that arranged in factorial (4x2) with three replications. The first fact

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Negative / Null Result ReportOpen accessScience

Fast-decaying tree litter reduces the temperature sensitivity of soil carbon decomposition by increasing microbial necromass carbon

Ruihan Li, Chuankuan Wang, Chunhua Lv et al. · 2025 · Geoderma

Improvements in stocks and stability of forest soil organic carbon can be achieved through the management of tree species. Given the long lifespan of trees and their role as the keystone species in forested ecosystems, decisions regarding tree species management can have a significant impact on soil carbon balance, with effects that may persist for decades. Here, a common garden experiment involving five temperate tree species in northeast China was conducted to quantify the influence of tree species on soil carbon dynamics, including its fractions (mineral-associated organic carbon, particula

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Negative / Null Result ReportOpen accessLanguage and Literature

The Acoustic Properties of Vowels in Foreigner-Directed Speech: Insights from Speech Directed at Foreign Domestic Helpers

Azza Al-Kendi · 2025 · Languages

This study examines the acoustic properties of vowels in foreigner-directed speech (FDS) in interactions between female Omani-Arabic-speaking employers and their foreign domestic helpers (FDHs). Particularly, it investigates whether Arabic corner vowels /i:/, /a:/, and /u:/ undergo acoustic adaptations in FDS. The study also explores the influence of foreign interlocutors’ psycholinguistic characteristics, such as degree of foreign accent, religion, and length of residence (LoR), on the extent of these adaptations. Data were collected from 22 Omani-Arabic-speaking women interacting with their

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Negative / Null Result ReportOpen accessPsychiatry

Hospital utilization rates following antipsychotic dose reductions: implications for tardive dyskinesia

Stanley N. Caroff, Fan Mu, Rajeev Ayyagari et al. · 2018 · BMC Psychiatry

Abstract Background Data are limited on the benefits and risks of dose reduction in managing side effects associated with antipsychotic treatment. As an example, antipsychotic dose reduction has been recommended in the management of tardive dyskinesia (TD), yet the benefits of lowering doses are not well studied. However, stable maintenance treatment is essential to prevent deterioration and relapse in schizophrenia. Methods A retrospective cohort study was conducted to analyze the healthcare burden of antipsychotic dose reduction in patients with schizophrenia. Medical claims from six US stat

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Negative / Null Result ReportOpen accessGeriatrics

Mifepristone Increases Life Span in Female Drosophila Without Detectable Antibacterial Activity

Gary N. Landis, Luke Riggan, Hans S. Bell et al. · 2022 · Frontiers in Aging

Mifepristone dramatically increases the life span of mated female Drosophila while reducing the expression of innate immune response genes. Previous results indicated that mifepristone also reduced the load of aero-tolerant bacteria in mated females. Experiments were conducted to further investigate the possible role of bacteria in mifepristone life span effects. Life span was assayed in flies grown from sterilized eggs on autoclaved media and in normally cultured controls in two independent assays. Sterilization increased mated female life span (+8.3% and +57%, respectively), and the effect o

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Negative / Null Result ReportOpen accessChemical technology

Characterization, Stability and Antioxidant Activity of Vanilla Nano-Emulsion and Its Complex Essential Oil

Fei Xu, Yucong Shi, Bin Li et al. · 2024 · Foods

As a natural flavoring agent, vanilla essential oil has a special aroma and flavor, but its volatility and instability limit its value. Therefore, in this study, vanilla essential oil was compounded with cinnamon essential oil to prepare nano-emulsions (composite nano-emulsions called C/VT and C/VM), and the stability of the composite essential oil emulsions was investigated. Transmission electron microscopy (TEM) images showed that the nano-emulsions were spherical in shape and some flocs were observed in C/VM and C/VT. The results showed that the average droplet sizes of C/VM and C/VT increa

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Negative / Null Result ReportOpen accessPsychology

The Impact of Cues on Joint Attention in Children with Autism Spectrum Disorder: An Eye-Tracking Study in Virtual Games

Lili Liu, Shuang Li, Lin Tian et al. · 2024 · Behavioral Sciences

Joint attention (JA), a core deficit in children with autism spectrum disorder (ASD), is crucial for social interaction, emotional understanding, and cognitive development. This study aims to compare and analyze the eye-tracking data of ASD and typically developing children (TDC) during virtual games, exploring how different cue types affect JA performance in ASD children. A total of 31 TDC and 40 ASD children participated in the study. Using eye-tracking devices, we recorded the children’s eye movements as they played virtual games, selecting the correct target based on cues provided by virtu

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Negative / Null Result ReportOpen accessEducation

Study on teacher performance determinants

Muhammad Ridwan, Sitti Rizki Mulyani, Rio Andhika Putra et al. · 2022 · JPPI (Jurnal Penelitian Pendidikan Indonesia)

The objective of this research was to see how salary, leadership support, and work-life balance affected teacher effectiveness. The non-probability sampling approach was applied, as well as a purposive sampling strategy. A total of 150 instructors from Padang City, West Sumatra, were employed in this study. SEM and AMOS 24.0 software were utilized in this study's analysis. Compensation has a considerable impact on teacher performance, according to the findings. Teachers' salary has a huge impact on their work-life balance. Support from leaders has a huge impact on teachers' work-life balance.

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Negative / Null Result ReportOpen accessMedicine

Systemic blockade of dopamine D2-like receptors increases high-voltage spindles in the globus pallidus and motor cortex of freely moving rats.

Chen Yang, Shun-Nan Ge, Jia-Rui Zhang et al. · 2013 · PLoS ONE

High-voltage spindles (HVSs) have been reported to appear spontaneously and widely in the cortical-basal ganglia networks of rats. Our previous study showed that dopamine depletion can significantly increase the power and coherence of HVSs in the globus pallidus (GP) and motor cortex of freely moving rats. However, it is unclear whether dopamine regulates HVS activity by acting on dopamine D₁-like receptors or D₂-like receptors. We employed local-field potential and electrocorticogram methods to simultaneously record the oscillatory activities in the GP and primary motor cortex (M1) in freely

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Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system

Rejuvenated Circulating Endothelial Progenitor Cells and Nitric Oxide in Premenopausal Women with Hyperhomocysteinemia

Long Peng, Qianlin Gu, Zhenhua Huang et al. · 2020 · Cardiology Research and Practice

Hyperhomocysteinemia (HHcy) induced endothelial dysfunction is associated with disturbance in circulating endothelial progenitor cells (EPCs). Nevertheless, whether this unfavorable effect of HHcy on circulating EPCs also exists in premenopausal women is still unknown. Therefore, this leaves an area for the investigation of the difference on the number and activity of circulating EPCs in premenopausal women with hyperhomocysteinemia and its underlying mechanism. The number of circulating EPCs was measured by fluorescence-activated cell sorter analysis, as well as DiI-acLDL and lectin fluoresce

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Negative / Null Result ReportOpen accessMedicine

A cephalometric study of nasopharynx in skeletal class I and III malocclusion

Mohamad Hosein Toodeh Zaeim, Soghra Yassaei, Hosein Aghili et al. · 2008 · Iranian Journal of Orthodontics

Aim: Nasopharyngeal space is estimated from a point on the posterior part of the soft palate till the nearest point on the wall of the pharynx and the aim of the present study was to study the nasopharyngeal indices in nasal breathers with class I and III malocclusions.Materials and Methods: This was a descriptive analytical study done by the case - control method on 35 lateral cephalometries of patients with skeletal Class III malocclusion as the study group and 30 lateral cephalometries of patients with skeletal Class I malocclusion as the control group. The population under study included p

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Negative / Null Result ReportOpen accessManagement. Industrial management

FACTORS AFFECTING RESEARCHERS PERFORMANCE IN THE INDONESIAN INSTITUTE OF SCIENCES

Sabrul Wasfi, Heti Mulyati, Joko Purwono · 2020 · Jurnal Aplikasi Manajemen

The Performance of Indonesian researchers is relatively low at the international and ASEAN levels. Moreover, LIPI (Indonesian Institute of Sciences) as one of the largest research institutions in Indonesia, its ranks on webometrics continue to decline. This study aims to prove the factors that influence the performance of LIPI researchers. This study aims to examine the effect of competence, training, organizational support, organizational climate, and researchers’ characteristics on performance. With a stratified proportional sampling data collection technique, we obtained 153 researchers in

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