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25 real negative results, null findings, and replication failures in Orthopedic surgery. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessOrthopedic surgery

Valgus cut angle and the factors affecting distal femoral cut in total knee arthroplasty in the Turkish population

Uğur Yüzügüldü, Enes Keleş, Harun Yasin Tüzün et al. · 2026 · Journal of Orthopaedic Surgery and Research

Abstract Background This study aims to comprehensively examine the distal femoral valgus cut angle (VCA) utilized during total knee arthroplasty (TKA) in the Turkish population and identify the radiological and demographic factors influencing this critical surgical parameter. Methods A retrospective analysis was performed on 193 lower extremity orthoradiographs from 120 patients diagnosed with end-stage knee osteoarthritis between January 2020 and December 2023. Key radiological variables assessed included VCA, mechanical femorotibial angle (MTFA), neck-shaft angle (NSA), medial offset (MO), a

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Negative / Null Result ReportOpen accessOrthopedic surgery

The changes in residual volume total lung capacity and vital capacity after the posterior fusion for adolescent idiopathic scoliosis

A. Sukru Solak, Erbil Aydin, Ersan Boysan et al. · 2021 · Acta Orthopaedica et Traumatologica Turcica

Abstract We evaluated pre and postoperative pulmonary functions of 48 patients who underwent posterior fusion for the adolescent idiopathic scoliosis. The mean age at the time of surgery was 13±1.5 years. Average follow-up time was 2.7 years. The predicted pulmonary volumes of the patients were used to eliminate any effect of the difference in age. In this study we didn t found any relation between the pre and postoperative frontal and sagittal plane Cobb angles and pulmonary volumes. Only for the residual volume there was a significant increase but the increase for the vital capacity and forc

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Negative / Null Result ReportOpen accessOrthopedic surgery

Lateral extra‐articular tenodesis improves functional movement outcomes in ACL reconstruction patients

Luyckx Thomas, Wen Zhishen, Kluyskens Louis et al. · 2025 · Journal of Experimental Orthopaedics

Abstract Purpose The primary aim was to evaluate the functional impact of adding lateral extra‐articular tenodesis (LET) to an anterior cruciate ligament (ACL) reconstruction (ACLR). The secondary aim was to assess whether LET provides benefits in muscle strength, patient‐reported outcome measures (PROMs) and return to sport (RTS) pass rate, as well as to examine the influence of meniscal injury on performance in ACLR patients. Methods A retrospective cohort of prospectively collected data on all ACL procedures was performed at AZ Delta Roeselare between 2017 and 2019. The patients followed a

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Negative / Null Result ReportOpen accessOrthopedic surgery

Inferior subluxation of humeral head after osteosynthesis for greater tuberosity fracture

Ryogo Furuhata, Atsushi Tanji, Satoshi Oki et al. · 2022 · Journal of Orthopaedic Surgery and Research

Abstract Background Inferior subluxation of the humeral head is frequently observed immediately after surgery for proximal humerus fractures; however, the incidence and risk factors of inferior subluxation after osteosynthesis for isolated greater tuberosity fractures remain unsolved. Additionally, the postoperative course of inferior subluxation has not been elucidated. The purpose of the present study is to identify the predictors for the occurrence of postoperative inferior subluxation by multivariate analysis and investigate the postoperative shift of inferior subluxation and its effect on

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Negative / Null Result ReportOpen accessOrthopedic surgery

Does Weber Classification Predict Patient Reported Outcomes using PROMIS Scores?

Steven M. Hadley BA, John J. Peabody MD, Sarah Westvold MPH et al. · 2024 · Foot & Ankle Orthopaedics

Category: Ankle; Trauma Introduction/Purpose: It remains unclear whether ankle fracture pattern as described by the Weber classification—a reproducible method describing the level of fracture with respect to the distal tibiofibular syndesmosis—impacts outcomes. Patient Reported Outcome Measurement Information System (PROMIS) is a validated measure of outcomes after foot and ankle surgery. To our knowledge, no study has compared PROMIS scores between Weber subtypes. Our study thus examines whether Weber fracture subtype impacts surgical outcomes as measured by PROMIS scores. We hypothesize that

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Negative / Null Result ReportOpen accessOrthopedic surgery

Elastic-stable intramedullary nailing for radial neck fractures in children: clinical and radiological outcomes and risks for poor prognosis

Michał Maciejewski, Piotr Janusz, Michalina Dudkiewicz et al. · 2023 · Chirurgia Narządów Ruchu i Ortopedia Polska

Introduction. Radial neck fractures in children are rare and account for 1-3% of all childhood trauma. Severe displacement of the fracture can lead to a higher incidence of complications, such as limited range of motion (ROM), pain, instability, neurovascular trauma, premature physeal closure, cubitus valgus, radial head overgrowth, avascular necrosis and improper ossification. The treatment outcome depends on the injury type, treatment method and presence of complications.Aim. The purpose of the study was to assess the outcome of patients treated with elastic-stable intramedullary nailing (ES

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Negative / Null Result ReportOpen accessOrthopedic surgery

Radiation Exposure and Safety in Minimally Invasive Foot and Ankle Surgery: A Comparative Analysis Between Minimally Invasive Distal First Metatarsal Transverse Osteotomy and Akin Osteotomy vs. Open Modified Lapidus Procedure

Preston Harrison BS, Sarah Kiriluk MD, Kevin Lee et al. · 2026 · Foot & Ankle Orthopaedics

Category: Midfoot/Forefoot, Bunion Diabetes Keywords: Ankle, Degenerative, Hindfoot Deformity Introduction/Purpose: Intraoperative fluoroscopy has become essential in orthopedic surgery, particularly with the rise of minimally invasive surgery (MIS) techniques. Despite the advantages of minimally invasive foot and ankle surgery, it raises concerns about radiation exposure to both patients and surgical staff. The purpose of this study was to evaluate fluoroscopy time and radiation dose (cumulative air kerma) associated with open versus MIS bunion correction, comparing the open modified Lapidus

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Negative / Null Result ReportOpen accessOrthopedic surgery

Accuracy of pedicle screw placement based on preoperative computed tomography versus intraoperative data set acquisition for spinal navigation system

Hao Liu, Weikai Chen, Tao Liu et al. · 2017 · Journal of Orthopaedic Surgery

Aim: To investigate the accuracy of pedicle screw placement based on preoperative computed tomography in comparison with intraoperative data set acquisition for spinal navigation system. Methods: The PubMed (MEDLINE), EMBASE, and Web of Science were systematically searched for the literature published up to September 2015. This review followed the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. Statistical analysis was performed using the Review Manager 5.3. The dichotomous data for the pedicle violation rate was summarized using relative risk (RR) and 95% confid

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Negative / Null Result ReportOpen accessOrthopedic surgery

A biomechanics study on ligamentous injury in anterior-posterior compression type II pelvic injury

Jianzhong Kong, Yupeng Chu, Chengwei Zhou et al. · 2021 · Journal of Orthopaedic Surgery and Research

Abstract Background Anterior-posterior compression (APC) type II pelvis fracture is caused by the destruction of pelvic ligaments. This study aims to explore ligaments injury in APC type II pelvic injury. Method Fourteen human cadaveric pelvis samples with sacrospinous ligament (SPL), sacrotuberous ligament (SBL), anterior sacroiliac ligament (ASL), and partial bone retaining unilaterally were acquired for this study. They were randomly divided into hemipelvis restricted and unrestricted groups. We recorded the separation distance of the pubic symphysis and anterior sacroiliac joint, external

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Negative / Null Result ReportOpen accessOrthopedic surgery

Measurement of midshaft clavicle vertical displacement is not influenced by radiographic projection

Paul Hoogervorst, MD, Aman Chopra, Zachary M. Working et al. · 2020 · JSES International

Background: Measured shortening of midshaft clavicle fracture fragments is known to be influenced by multiple factors. The influence of radiographic projection on vertical displacement is unclear. The aims of this study were (1) to quantify the difference in measurements of vertical displacement in an absolute, relative, and categorical manner between 5 different projections; (2) to quantify the differences in interobserver and intraobserver agreement using a standardized method for measuring vertical displacement; and (3) to assess the association between categorical and continuous descriptio

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Negative / Null Result ReportOpen accessOrthopedic surgery

[Translated article] Analysis of the results of anterior cruciate ligament reconstruction associated with high-resistance tape reinforcement (ultra-high molecular weight polyethylene braided material)

A.N. Toro-Ibarguen, E. Sánchez Benito, J.M. Cortés Villar · 2026 · Revista Española de Cirugía Ortopédica y Traumatología

Background and objective: The primary objective is to evaluate the clinical and functional outcomes of tape reinforcement in anterior cruciate ligament (ACL) reconstructions, recording complications, as well as the rate of reinterventions and graft failure. Materials and methods: Retrospective analysis of ACL reconstructions with hamstring (HS) autograft that were reinforced with high-strength tape. We included patients in whom we obtained a graft of HS <8 mm or ≥8 mm of poor quality. Age, sex, body mass index (BMI), and previous activity were recorded. Clinical and functional evaluation were

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Failed Experiment ReportOpen accessOrthopedic surgery

Posterior Ankle and Hindfoot Arthroscopy: Complications and Posterior Ankle Impingement Pathologies

Karthikeyan Chinnakkannu MD, John E Femino MD, Natalie Glass PhD et al. · 2019 · Foot & Ankle Orthopaedics

Category: Ankle, Arthroscopy, Hindfoot, Sports Introduction/Purpose: Posterior ankle/hindfoot arthroscopy (PAHA) is an established surgical option for treating pathologies, of posterior ankle and subtalar joints, which otherwise would require open incisions. Arthroscopic procedures are less invasive, provide magnified visualization and allow earlier rehabilitation and return to activity. Many studies have reported outcomes after PAHA, however only two studies have reported complications in larger cohorts. Although posterior ankle impingement (PAI) is a common indication for PAHA, it is a non-s

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Negative / Null Result ReportOpen accessOrthopedic surgery

Longitudinal Pulmonary Function After Surgical Treatment of Early-Onset Scoliosis

Scott Yang, MD, Apeksha Gupta, MS, MPH, Michael E. Trask, BS et al. · 2025 · JBJS Open Access

Background:. Longitudinal pulmonary outcomes after surgical treatment of early-onset scoliosis (EOS) are not well reported. This study aims to evaluate change in serial pulmonary function in children with EOS after surgery. Methods:. A retrospective review was performed at a single academic hospital. All patients who had surgical treatment of EOS and repeated pulmonary function test (PFT) data were included. Pulmonary function test (PFT) measures included forced vital capacity (FVC), FVC % of predicted norms (FVC%), forced expiratory volume in 1 second (FEV1), and FEV1% of predicted norms (FEV

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Negative / Null Result ReportOpen accessOrthopedic surgery

In vivo cartilage tissue engineering

B. Gurer, S. Cabuk, O. Karakus et al. · 2018 · Journal of Orthopaedic Surgery and Research

Abstract Background Biologic treatment options for cartilage injuries require chondrocyte expansion using cell culture. Clinical application is accomplished in two surgical sessions and is expensive. If isolation of chondrocytes and stimulus for proliferation and extracellular matrix synthesis can be achieved in vivo, the treatment can be performed in one session and the cost can be reduced. Methods A 2.5-cm diameter full-thickness chondral defect was created in the knees of five groups of sheep. In one group, some of the chondral tissues obtained from the creation of the defect were diced int

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Negative / Null Result ReportOpen accessOrthopedic surgery

Infection Rates in Open Fractures of the Tibia: Is the 6-Hour Rule Fact or Fiction?

Ameya S. Kamat · 2011 · Advances in Orthopedics

Aims. Emergency debridement has long been the standard of care for open fractures of the tibia as infection is an important complication. The timing of operative debridement can be debated. We review open fractures of the tibia and compare infection rates in those that were operated on within and after 6-hours. Method. 103 consecutive open fractures of the tibia were reviewed. The data was analysed retrospectively with regard to severity of fracture and incidence of infection. Infection rates over a three-month period were compared between the two groups. Results. 12 (11.6%) patients developed

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Negative / Null Result ReportOpen accessOrthopedic surgery

Relationship between the carrying angle, medial instability of the elbow, and general joint laxity in high school baseball pitchers: a cross-sectional study

Koichiro Yanai, MD, Tsuyoshi Tajika, MD, PhD, Yuhei Hatori, MD et al. · 2025 · JSES International

Background: An increase in carrying angle (CA) on the throwing side has been reported in professional baseball pitchers. However, no reports have investigated high school baseball pitchers, and the associated factors remain unknown. This study aimed to examine the difference in the CA between the throwing and nonthrowing sides in high school baseball pitchers and to investigate the association between the CA and medial instability of the elbow and general joint laxity (GJL). Methods: We surveyed 216 high school baseball pitchers who underwent medical checkups during the 2023-24 off-season. All

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Negative / Null Result ReportOpen accessOrthopedic surgery

Survival Comparison Following Below-the-Knee Amputation in Diabetic Patients with and without Hemodialysis

Jaehyung Lee, Janghyun Kim, Sungkuk Chae et al. · 2024 · Foot & Ankle Orthopaedics

Category: Diabetes; Other Introduction/Purpose: Foot ulcers and subsequent amputations are disabling complications in diabetic patients, and major amputations, including below-knee amputations, leave patients with catastrophic disabilities. Diabetes is the most common cause of causing end-stage renal disease which results in hemodialysis, and patients with diabetes on hemodialysis have a higher prevalence of several co-morbidities compared to those without diabetes. The purpose of this study is to compare survival rates after below knee amputation in patients with diabetes who are on hemodialy

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Negative / Null Result ReportOpen accessOrthopedic surgery

Does preoperative mental health affect length of hospital stay and functional outcomes following arthroplasty surgery? A registry-based cohort study

Neal Singleton, Vaughan Poutawera · 2017 · Journal of Orthopaedic Surgery

Aim: It has been reported in the literature that patients with poor preoperative mental health are more likely to have worse functional outcomes following primary total hip and knee arthroplasty. We could find no studies investigating whether preoperative mental health also affects length of hospital stay following surgery. The aim of this study was to determine whether preoperative mental health affects length of hospital stay and long-term functional outcomes following primary total hip and knee arthroplasty. We also aimed to determine whether mental health scores improve after arthroplasty

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Negative / Null Result ReportOpen accessOrthopedic surgery

Comparison of simultaneous bilateral with unilateral total knee arthroplasty

Yakup Ekinci, Mithat Oner, Ibrahim Karaman et al. · 2020 · Acta Orthopaedica et Traumatologica Turcica

Abstract Objective: The aim of this study was to compare simultaneous bilateral total knee arthroplasty (BTKA) and unilateral total knee arthroplasty (UTKA) in terms of morbidity, clinical and radiological findings and quality of life. Methods: The study included 48 simultaneous BTKAs (46 females, 2 males; mean age: 64.00±8.31 years) and 53 UTKAs (46 females, 7 males; mean age: 64.40±7.45 years) performed between November 2007 and June 2012. Groups were compared with respect to comorbidity, complications, blood transfusion, hospital stay, clinical and radiological (American Knee Society Score)

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Negative / Null Result ReportOpen accessOrthopedic surgery

Effects of NSAIDs and hydroxyapatite coating on osseointegration

Ahmet Salduz, Fatih Dikici, Önder Ismet Kılıçoğlu et al. · 2017 · Journal of Orthopaedic Surgery

Purpose: The aim of our study is to investigate the bone ongrowth of two different alternative surfaces and the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on osseointegration. Methods: Hips of 40 New Zealand white rabbits were operated bilaterally. Hydroxyapatite (HA)-coated titanium rods were implanted into the right femur, and grit-blasted titanium rods were implanted into the left femur. They were divided into three groups. At the end of 8 weeks, both femora of the rabbits were removed and investigated biomechanically and histologically. Results: HA-coated implants had a signif

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Negative / Null Result ReportOpen accessOrthopedic surgery

The application of “upper-body yoga” in elderly patients with acute hip fracture: a prospective, randomized, and single-blind study

Jinli Guo, Chaona Gao, Haifeng Xin et al. · 2019 · Journal of Orthopaedic Surgery and Research

Abstract Purposes Hip fracture leads to decreased activity and an increased risk of pulmonary complications. The main purpose of this study was to observe the lung capacity, cough capacity of the elderly patient with acute hip fracture, and assess the effects and the feasibility of using a special-designed “upper-body yoga” training to treat elderly patients with hip fracture. Methods This was a prospective, randomized, and single-blind study. Eighty-four subjects aged over 65 years were randomly divided into either a control group or a yoga group to undergo an abdominal breathing program or a

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Negative / Null Result ReportOpen accessOrthopedic surgery

Comparison of the two surgery methods combined with accelerated rehabilitation in the treatment of lateral compression type 1 pelvic fractures in the elderly

Min Zou, Xin Duan, Mufan Li et al. · 2023 · Journal of Orthopaedic Surgery and Research

Abstract Background Treating lateral compression type 1 (LC1) pelvic ring injuries in older patients is controversial. This study evaluated surgical treatments combined with ERAS for treating LC1 pelvic fractures in the elderly. Methods In this retrospective study, patients who underwent surgery with INFIX (supra-acetabular spinal pedicle screws, and a subcutaneous connecting rod; the experimental group) or superior pubic ramus cannulated screw (the control group) fixation of LC1 pelvic fracture from January 2019 to January 2022 were reviewed. Injury radiography and computed tomography were pe

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Negative / Null Result ReportOpen accessOrthopedic surgery

Development of a cadaveric Hallux Rigidus model. Biomechanical testing

Diego Zanolli de Solminihac MD, Emilio Wagner MD, Pablo Wagner MD et al. · 2017 · Foot & Ankle Orthopaedics

Category: Bunion Introduction/Purpose: Hallux Rigidus (HR) is characterized initially by a decrease in Hallux metatarsophalangeal joint (MTPJ) dorsiflexion, decreasing the total range of motion. To be able to study different surgical treatment options, a cadaveric model has to be developed that recreates the limited range of motion. Our objective was to develop an Hallux Rigidus cadaveric model by shortening the plantar fascia (PF). Hallux MTPJ range of motion and joint stiffness were evaluated. Methods: 8 cadaveric foot- ankle – distal tibia specimens were prepared, identifying all extensor a

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Negative / Null Result ReportOpen accessOrthopedic surgery

Comparison of peripheral nerve block with local infiltration analgesia regarding walking ability after total knee replacement: A retrospective, propensity-score matched-pair cohort study

Taeko Fukuda, Shinobu Imai, Shunji Simoda et al. · 2020 · Journal of Orthopaedic Surgery

Purpose: It is unclear whether perioperative analgesic techniques affect the functional outcome of total knee replacement (TKR). We investigated the effects of peripheral nerve block (PNB) and local infiltration (LI) on walking ability after TKR. Methods: The medical records of 7143 patients who underwent TKR using general anesthesia with PNB or LI techniques were reviewed. Factors affecting independence and/or improvement of walking after surgery were investigated using multivariate regression analysis. To adjust for baseline differences and minimize selection bias for the chosen analgesic te

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Negative / Null Result ReportOpen accessOrthopedic surgery

A comparison of healing and complication rates between common flaps utilized in total knee arthroplasty: a review of the literature

Akhil A. Chandra, Filippo Romanelli, Alex Tang et al. · 2022 · Knee Surgery & Related Research

Abstract Background Flap reconstruction with perforator, fasciocutaneous, muscular, and/or free microvascular flaps is utilized to cover wound defects and improve vascularization and antibiotic/nutrient delivery. Flap use in revision procedures for total knee arthroplasty has been explored previously; however, current data are limited and studies comparing healing and complication rates between different flap types are lacking. Methods A literature review was performed using PubMed on 13 January 2022. Studies were included if they reported healing and complication rates for either gastrocnemiu

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