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Browse the failure-mode index

13 real negative results, null findings, and replication failures in Science (General). Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessScience (General)

Relationships Between pH Buffer Capacity and Selected Soil Properties of an Agrarian area in Samaru, Nigeria

Ayodele Owonubi, Favour Kenneth Chiwendu · 2022 · UMYU Scientifica Journal

The objectives of this research were to investigate the nature of pH buffer capacity and evaluate its association selected soil characteristics the study area. Soil samples from ten profile pits from within the study area were collected from genetic horizons. Soil samples were tested in the laboratory for electrical conductivity and pH buffer capacity using standard procedures. Soil data were analyzed using descriptive statistics. One-way analysis of variance and correlation analysis were applied to determine effects and relationships of selected soil properties with soil pH buffer capacity. T

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Negative / Null Result ReportOpen accessScience (General)

Knowledge, attitude, and practice toward leukemia in the general population and among family members of patients with leukemia: A cross-sectional study

Fengbo Jin, Wanlu Tian, Leiming Xia et al. · 2024 · Heliyon

Background: Patients with leukemia rely on social and family support. This study aimed to explore the knowledge, attitude, and practice (KAP) toward leukemia among family members of patients with leukemia and the general population in southeast China. Methods: A cross-sectional study was conducted in September 2022 in southeast China (Anhui Province). The KAP scores and demographic data were assessed by questionnaire and analyzed by multivariable logistic regression and structural equation modeling. Results: A total of 760 valid questionnaires were collected, including 117 (15.39%) answered by

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Negative / Null Result ReportOpen accessScience (General)

The effect of beer and milk tea on the shear bond strength of adhesive precoated brackets: An in vitro comparative study

Weerada Vorachart, Nonglak Sombuntham, Kulthida Parakonthun · 2022 · Heliyon

Objectives: The objectives of this study were to evaluate the long-term effects of beer and milk tea on the shear bond strength (SBS) of adhesive precoated brackets and conventional adhesive on brackets. Methods: The 150 metal brackets were bonded to maxillary permanent premolars and divided into two groups based on adhesive type: (1) Transbond PLUS Color Change Adhesive (TP) and (2) Flash-Free adhesive precoated (APC FF). The bonding processes were carried out exactly as recommended by the manufacturer. Each group’s samples were randomly divided into five subgroups with different immersion so

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Negative / Null Result ReportOpen accessScience (General)

Influence of Culture Tank Colours on the Water Quality, Growth Performance and Feed Utilization of Oreochromis niloticus (Linnaeus, 1758) Juveniles

Akeem Dauda Babatunde, Hafsah Maiazara Adamu, Hauwau Abubakar Salele · 2023 · UMYU Scientifica Journal

The study was conducted over a period of fifty-six (56) days to investigate the effects of different colours of culture tanks on the water quality, growth, and feed utilization of Nile tilapia (Oreochromis niloticus) juveniles. O. niloticus of mean body weight of 8.5g were stocked and fed twice daily with a commercial diet containing 42% crude protein. The experiment had four treatments based on tank colours; white, green, black and blue coloured tanks. Some water quality indices were assessed once in a week while the fish were weighed at the end of the experiment to compute the performance in

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Negative / Null Result ReportOpen accessScience (General)

Evaluation of motility and morphology of frozen bull semen under different thawing methods used for artificial insemination in North Shewa zone, Ethiopia

Shenkute Goshme, Tadiws Asfaw, Chekol Demiss et al. · 2021 · Heliyon

The frozen bull semen straws were gathered from three specifically chosen locations in the North Shewa Zone, namely Baso, Chacha, and Debre-Birhan town, and the laboratory work was carried out at the Debre Birhan agricultural research center. The researchers wanted to see how different thawing methods affected the mass motility of frozen bull sperm. The thawing protocols used for mass motility evaluation were 37 °C for 30 s, 35 °C for 40 s, 40 °C for 40 s, body temperature using a hand for 15 s and body temperature using a hand for 30 s by using a water bath. The mass motility of the frozen bu

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Negative / Null Result ReportOpen accessScience (General)

In vitro response of dental pulp stem cells in 3D scaffolds: A regenerative bone material

Nury Tatiana Jiménez, Juan Carlos Munévar, José Manuel González et al. · 2018 · Heliyon

Three-dimensional-porous scaffolds of bone graft substitutes play a critical role in both cell targeting and transplantation strategies. These scaffolds provide surfaces that facilitate the response of stem cells related to attachment, survival, migration, proliferation, and differentiation. Objective: The aim of this study was to evaluate the in vitro behavior of human dental pulp mesenchymal stem cells cultured on scaffolds of polylactic/polyglycolic acid with and without hydroxyapatite. Method: We performed an in vitro experimental study using dental pulp stem cells obtained from samples of

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Negative / Null Result ReportOpen accessScience (General)

Determination of cyberloafing level of speech and Language Therapy Department students

Fenise Selin Karali, Samet Tosun, Meltem Şen-Aksüt et al. · 2024 · Heliyon

Cyberloafing is the use of (e.g. smartphones, tablets, laptops, and the Internet) for purposes other than work related reasons during work hours. Although cyberloafing in the workplace has been widely investigated, there is relatively a small number of studies on cyberloafing behaviors in educational settings, which refer to students' tendencies to use technology for non-class-related purposes during lectures. The goal of the current study is to determine how frequently and for what purposes speech and language therapy (SLT) students at Biruni University engage in cyberloafing during lectures.

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Negative / Null Result ReportOpen accessScience (General)

Expression of interferon-stimulated genes, but not polymorphisms in the interferon α/β receptor 2 gene, is associated with coronavirus disease 2019 mortality

Berliana Hamidah, Cennikon Pakpahan, Laksmi Wulandari et al. · 2024 · Heliyon

Excessive inflammatory response is a hallmark of severe COVID-19. This study investigated the associations between interferon-stimulated genes (ISGs) expression, genetic variation in the interferon α/β receptor 2 (IFNAR2) gene, and COVID-19 mortality.We investigated 67 patients with moderate-to-severe COVID-19. Of them, 22 patients (32.8 %) died because of COVID-19. We examined the expression of ISGs in total RNA of peripheral whole blood. We observed a significant increase in the expression of all ISGs examined in non-surviving patients, indicating a heightened interferon type I signaling act

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Negative / Null Result ReportOpen accessScience (General)

Excessive bowel volume loss during anus-preserving surgery for rectal cancer affects the bowel function after operation: A prospective observational cohort study (Bas-1611)

Fan Liu, Peng Guo, Quan Wang et al. · 2023 · Heliyon

Background: Bowel volume loss during anus-preserving surgery (APS) may result in low anterior resection syndrome (LARS). We conducted this prospective observational cohort study to measure the incidence of LARS after surgery and evaluate the relationship between bowel volume loss and bowel function. Methods: Patients with R0 resectable rectal cancer who consented to several bowel function surveys through telephone interviews after the operation were included. Enrolled patients underwent standard APS for rectal cancer, and three length indexes, viz. length of excised bowel, length of the distal

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Negative / Null Result ReportOpen accessScience (General)

Clinical significance of serum lactate and lactate dehydrogenase levels for disease severity and clinical outcomes in patients with colorectal cancer admitted to the intensive care unit

Xin Wang, Chen Li, Ming Li et al. · 2024 · Heliyon

Objective: Serum lactate (LA) and lactate dehydrogenase (LDH) levels have a major impact on the clinical treatment of malignant tumors and critically ill patients. Nevertheless, the assessment of disease severity in oncology patients admitted to the intensive care unit (ICU) remains incomplete when considering the serum LA and LDH levels. This study aimed to investigate the significance of serum LDH and LA levels in assessing disease severity and predicting clinical outcomes in patients with colorectal cancer (CRC) admitted to the ICU. Methods: This retrospective study included patients with C

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Negative / Null Result ReportOpen accessScience (General)

Evaluation of genetic correlation with fluoroquinolones resistance in rifampicin-resistant Mycobacterium tuberculosis isolates

Chong Teng, Ling Li, Dan Su et al. · 2024 · Heliyon

Objective: To detect levofloxacin (LFX) and moxifloxacin (MFX) resistance among rifampicin-resistant tuberculosis (RR-TB) isolates, and predict the resistance level based on specific mutations in gyrA and gyrB genes. Methods: A total of 686 RR-TB isolates were collected from Chinese Drug Resistance Surveillance Program from 2013 to 2020. The minimum inhibitory concentrations (MICs) of 12 anti-TB drugs were acquired using the broth microdilution method, followed by whole genome sequencing (WGS) analysis. Results: Among the 686 RR isolates, the most prevalent resistance was to isoniazid (80.5 %)

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Negative / Null Result ReportOpen accessScience (General)

Hypnosis and nitrous oxide impact on the school aged patients’ anxiety and cooperation candidate for tooth extraction: A randomized clinical trial

Afsoon Motallebi, Mehdi Fathi, Fatemeh Mazhari et al. · 2024 · Heliyon

Background: This randomized clinical trial (RCT) investigated whether hypnosis would lead to favorable outcomes in reducing anxiety, enhancing cooperation, and improving physiological responses in school-aged children undergoing tooth extraction compared to nitrous oxide/oxygen (N2O/O2) and conventional behavior guidance (CBG). Methods: Sixty-six school-aged children (mean age: 7.87 ± 1.18 years) who needed one posterior primary tooth extraction were included. Children with low-to-moderate anxiety were randomly divided into three groups (n = 22 each): hypnosis, N2O/O2, and CBG. Anxiety levels

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Negative / Null Result ReportOpen accessScience (General)

The Effect of Different Soil Tillage Techniques on Weed Density, Yield And Some Yield Components of Lentil (Lens culinaris Medik.)

Hasan Kılıç, Zübeyir Türk · 2016 · Trakya University Journal of Natural Sciences

The study in which different soil tillage methods (conventional, reduced and zero tillage) and control methods of narrow leaved weeds were compared was carried out in dry farming conditions in Diyarbakır during growing season of the years 2004-2005. The weeds density, yield and yield components of lentil (Lens culinaris Medik.) were investigated. A significant difference was found between the herbicide applied (HER-1) and herbicide free groups (HER-2) (p<0.05) in terms of biological yield, harvest index, number of pods and seed per plant but there was no significant difference between the two

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