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10 real negative results, null findings, and replication failures in Computer applications to medicine. Medical informatics. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

A Survey Study on the Impact of Contextual Variables on Medical Students’ Use of Health Messenger Media

Mehrvash Moradi, Zahra Karimian, Nahid Zarifsanaiey · 2023 · Interdisciplinary Journal of Virtual Learning in Medical Sciences

Background: Medical students receive health information from various media sources and messages. Receiving health information can have a significant impact on the students’ dietary habits and healthy lifestyles. This study aimed to investigate the status of medical students’ use of health media and messaging, as well as the contextual variables that affect it.Methods: A survey study was conducted on 500 students of Shiraz University of Medical Sciences during September to December 2022 that were selected by simple random sampling. The research tool was a researcher-made questionnaire consistin

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

Impact of News Portrayals of Physicians as Vulnerable on the Public’s Evaluation and Trust in Physicians Under Different Involvement Levels: Quantitative Study

Qiwei Li, Jie Zhou · 2025 · Journal of Medical Internet Research

BackgroundNews portrayals of physicians, especially in China, often depict them as vulnerable—overworked, with inadequate compensation, or as victims of violence. These portrayals may send mixed signals to the public, yet their impact remains underexplored. Understanding their impact is essential for informing media strategies and improving physician-patient relationships. ObjectiveThis study investigated how portrayals of physicians as vulnerable influence public evaluations of their competence, warmth, morality, and overall trust and considered the moderating effects of involvement (ie, hosp

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

The Impact of Stay-At-Home Mandates on Uncertainty and Sentiments: Quasi-Experimental Study

Carolina Biliotti, Nicolò Fraccaroli, Michelangelo Puliga et al. · 2025 · Journal of Medical Internet Research

BackgroundAs the spread of the SARS-CoV-2 virus coincided with lockdown measures, it is challenging to distinguish public reactions to lockdowns from responses to COVID-19 itself. Beyond the direct impact on health, lockdowns may have worsened public sentiment toward politics and the economy or even heightened dissatisfaction with health care, imposing a significant cost on both the public and policy makers. ObjectiveThis study aims to analyze the causal effect of COVID-19 lockdown policies on various dimensions of sentiment and uncertainty, using the Italian lockdown of February 2020 as a qua

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

A Brief Intervention to Increase Uptake and Adherence of an Internet-Based Program for Depression and Anxiety (Enhancing Engagement With Psychosocial Interventions): Randomized Controlled Trial

Philip J Batterham, Alison L Calear, Matthew Sunderland et al. · 2021 · Journal of Medical Internet Research

BackgroundPsychosocial, self-guided, internet-based programs are effective in treating depression and anxiety. However, the community uptake of these programs is poor. Recent approaches to increasing engagement (defined as both uptake and adherence) in internet-based programs include brief engagement facilitation interventions (EFIs). However, these programs require evaluation to assess their efficacy. ObjectiveThe aims of this hybrid implementation effectiveness trial are to examine the effects of a brief internet-based EFI presented before an internet-based cognitive behavioral therapy self-

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

Adherence to Blended or Face-to-Face Smoking Cessation Treatment and Predictors of Adherence: Randomized Controlled Trial

Siemer, Lutz, Brusse-Keizer, Marjolein G J, Postel, Marloes G et al. · 2020 · Journal of Medical Internet Research

BackgroundBlended face-to-face and web-based treatment is a promising way to deliver smoking cessation treatment. Since adherence has been shown to be an indicator of treatment acceptability and a determinant for effectiveness, we explored and compared adherence and predictors of adherence to blended and face-to-face alone smoking cessation treatments with similar content and intensity. ObjectiveThe objectives of this study were (1) to compare adherence to a blended smoking cessation treatment with adherence to a face-to-face treatment; (2) to compare adherence within the blended treatment to

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

The Impact of Digital Technology–Based Exercise Combined With Dietary Intervention on Body Composition in College Students With Obesity: Prospective Study

Chengyuan Hu, Zixin Lv, Jieping Zhu et al. · 2025 · Journal of Medical Internet Research

BackgroundLifestyle interventions are a critical component of weight loss programs, yet digital, personalized, and theory- and evidence-based lifestyle interventions remain limited. ObjectiveThis study aimed to investigate the effects of a combination of various dietary approaches and digital technology–based exercise on the body composition of college students with obesity. MethodsA total of 129 college students with obesity (mean age 18.3, SD 0.7 years; mean weight 89.9, SD 13.6 kg; mean BMI 30.6, SD 3.3 kg/m2) were initially recruited for this study. After excluding 2 participants, 127 stud

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

Health-related quality of life and self-related health in patients with type 2 diabetes: Effects of group-based rehabilitation versus individual counselling

Vadstrup Eva S, Frølich Anne, Perrild Hans et al. · 2011 · Health and Quality of Life Outcomes

Abstract Background Type 2 diabetes can seriously affect patients' health-related quality of life and their self-rated health. Most often, evaluation of diabetes interventions assess effects on glycemic control with little consideration of quality of life. The aim of the current study was to study the effectiveness of group-based rehabilitation versus individual counselling on health-related quality of life (HRQOL) and self-rated health in type 2 diabetes patients. Methods We randomised 143 type 2 diabetes patients to either a six-month multidisciplinary group-based rehabilitation programme in

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

Effect of Integrated Personalized Health Care System on Middle-Aged and Elderly Women's Health

Hiye-Ja Lee, Kyung-Ja Kang, Seung-Hun Park et al. · 2012 · Healthcare Informatics Research

ObjectivesBody weight, body mass index (BMI), body fat, and blood pressure are important indicators of a person's health. In this experimental study, we evaluated the effectiveness of an integrated personalized health care system, Health Improvement and Management System (HIMS)-everyday, which instantly provides subjects with biofeedback on their measured body weight, BMI, body fat and blood pressure using a database that stores subjects-customized information.MethodsThe subjects of this study used the system once or twice a week for 8 weeks. We analyzed the changes in their body weight, BMI,

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

Postdischarge Video Visits for Adherence to Hospital Discharge Recommendations: A Randomized Clinical Trial

Sagar B. Dugani, MD, PhD, MPH, Shangwe A. Kiliaki, CNP, DNP, Megan L. Nielsen, MSN, CNP et al. · 2023 · Mayo Clinic Proceedings: Digital Health

Objective: To determine whether a postdischarge video visit with patients, conducted by hospital medicine advanced practice providers, improves adherence to hospital discharge recommendations. Patients and Methods: We conducted a single-institution 2-site randomized clinical trial with 1:1 assignment to intervention vs control, with enrollment from August 10, 2020, to June 23, 2022. Hospital medicine patients discharged home or to an assisted living facility were randomized to a video visit 2-5 days postdischarge in addition to usual care (intervention) vs usual care (control). During the vide

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Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics

Investigation of scanning parameters for thyroid fine needle aspiration cytology specimens: A pilot study

Maheswari S Mukherjee, Amber D Donnelly, Elizabeth R Lyden et al. · 2015 · Journal of Pathology Informatics

Background: Interest in developing more feasible and affordable applications of virtual microscopy in the field of cytology continues to grow. Aims: The aim of this study was to investigate the scanning parameters for the thyroid fine needle aspiration (FNA) cytology specimens. Subjects and Methods: A total of twelve glass slides from thyroid FNA cytology specimens were digitized at ×40 with 1 micron (μ) interval using seven focal plane (FP) levels (Group 1), five FP levels (Group 2), and three FP levels (Group 3) using iScan Coreo Au scanner (Ventana, AZ, USA) producing 36 virtual images (VI)

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