Negative / Null Result ReportOpen accessMedical technology
Huali Zhou, Alan Kan, Guangzheng Yu et al. · 2022 · IEEE Transactions on Neural Systems and Rehabilitation Engineering
The temporal-limits-encoder (TLE) strategy has been proposed to enhance the representation of temporal fine structure (TFS) in cochlear implants (CIs), which is vital for many aspects of sound perception but is typically discarded by most modern CI strategies. TLE works by computing an envelope modulator that is within the temporal pitch limits of CI electric hearing. This paper examines the TFS information encoded by TLE and evaluates the salience and usefulness of this information in CI users. Two experiments were conducted to compare pitch perception performance of TLE versus the widely-use
View details →Negative / Null Result ReportOpen accessMedical technology
Jinsoo Rhu, Kyo Won Lee, Young Jae Chung et al. · 2019 · Korean Journal of Transplantation
Background : This study aimed to develop and validate the Kidney Transplantation and Quality of Life (KTQoL) questionnaire to evaluate the quality of life (QoL) in Korean kidney transplantation (KT) patients. During the validation, the KTQoL was used to compare the QoL of KT patients before and after conversion from twice-daily to a once-daily regimen of tacrolimus.Methods : Construct and content validity of the 24-item KTQoL was evaluated using factor analysis and a panel of experts, respectively. The questionnaire was validated in 50 KT patients, conducted before and after conversion from tw
View details →Negative / Null Result ReportOpen accessMedical technology
Mona Makita, Shinichi Kawamoto, Momoko Nagai-Tanima et al. · 2025 · Biomedical Engineering Advances
The ground reaction force (GRF) waveform during countermovement jumps (CMJs) is considered to reflect neuromuscular coordination strategies; yet the biomechanical mechanisms distinguishing unimodal from bimodal patterns remain unclear. This study investigated the influence of countermovement depth and velocity on GRF waveform shape and examined their relationship with joint moments and work. Twenty-six healthy young women (age: 22.1 ± 1.1 years; height: 160.8 ± 4.0 cm; body weight: 53.5 ± 5.6 kg) performed CMJs, and GRF waveforms were categorised as unimodal and bimodal patterns. Jump-related
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Jian Zhang, Guohai Sun, Lei Zhang et al. · 2025 · Journal of Medical Ultrasound
Background: This study aimed to investigate the effects of combining an ilioinguinal/iliohypogastric nerve block with an ultrasound-guided quadratus lumborum block during inguinal surgery in older patients. Methods: Between December 2020 and June 2023, 300 elderly patients who underwent inguinal surgery at our institution were randomly divided into an observation group (n = 150) and a control group (n = 150). The observation group received ultrasound-guided quadratus lumborum block in addition to ilioinguinal/iliohypogastric nerve block, whereas the control group received only ultrasound-guide
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Simon Marchant, Shona Michael, Laura Milner et al. · 2019 · Journal of Rehabilitation and Assistive Technologies Engineering
Introduction Functional electrical stimulation uses clinician-set parameters to modify stimulation. This study aimed to investigate whether timing parameters in the ODFS Pace functional electrical stimulation device have an effect on the gait of the general population of functional electrical stimulation users who have a foot drop. Methods Twelve functional electrical stimulation users with foot drop resulting from upper motor neurone disorders were recruited from the functional electrical stimulation Service in Leeds, UK. A crossover trial design was used, comparing adjusted values of rising
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Mike J Crawford, Christian Gold, Helen Odell-Miller et al. · 2017 · Health Technology Assessment
Background: Preliminary studies have indicated that music therapy may benefit children with autism spectrum disorders (ASD). Objectives: To examine the effects of improvisational music therapy (IMT) on social affect and responsiveness of children with ASD. Design: International, multicentre, three-arm, single-masked randomised controlled trial, including a National Institute for Health Research (NIHR)-funded centre that recruited in London and the east of England. Randomisation was via a remote service using permuted blocks, stratified by study site. Setting: Schools and private, voluntary and
View details →Negative / Null Result ReportOpen accessMedical technology
Carlo Calabrese, Carlo Calabrese, Dania Gelli et al. · 2022 · Frontiers in Medical Technology
BackgroundCrohn's disease (CD) is a potentially debilitating condition that burdens Italian healthcare substantially. The symptomatic management relies on prompt therapy adjustment to reduce flares and follow-up diagnostic inputs to maximise remission. Capsule endoscopy (CE) has introduced advantages in CD diagnostics, allowing the direct inspection of the entire gastrointestinal mucosa. The diagnostic procedure is comparable in effort to standard ileocolonoscopy (IC) but requires no anaesthesia. Whether CE follow-up improves clinical outcomes remains to be defined.ObjectivesTo provide a preli
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