Negative / Null Result ReportOpen accessOphthalmology
V S Vijitha, Tarjani Vivek Dave, Somasheila I Murthy et al. · 2021 · Indian Journal of Ophthalmology
Purpose: To describe a series of sight-threatening ocular and adnexal involvement associated with dengue hemorrhagic fever and their treatment options. Methods: Retrospective, interventional, non-comparative case series. Medical records of patients who presented with ocular symptoms attributed to dengue hemorrhagic fever were reviewed. Demography, presenting features, and treatment outcomes were recorded. Outcome measures assessed included globe salvage, vision salvage, and visual improvement. The outcome was deemed as favorable if vision salvage was possible and unfavorable if the vision was
View details →Negative / Null Result ReportOpen accessOphthalmology
Saeed Shokoohi-Rad, Seyedeh Zeinab Hashemi Javaheri, Fatemeh Zare Malekabad et al. · 2020 · Indian Journal of Ophthalmology
Purpose: The aim of the present study was to compare the effects of the preoperative doses of betamethasone acetate 0.1% and placebo on controlling dry eye after cataract surgery. Methods: This randomized triple-blind clinical trial was conducted on 62 patients. For the purpose of the study, the participants were assigned into two groups of betamethasone (n = 28) and placebo (n = 34). The groups were administered with drops A or B three days before the operation, four times a day. These drops contained either betamethasone 0.1% or normal saline (placebo). Postoperative follow-up was performed
View details →Negative / Null Result ReportOpen accessOphthalmology
Jehan Fauzi Rakhmandani, Indra Tri Mahayana, Felicia Widyaputri et al. · 2023 · Taiwan Journal of Ophthalmology
PURPOSE: To assess the change of interleukin-6 (IL-6) levels in tears and ocular clinical parameters in corneal ulcer patients with moderate-to-severe infection after adjunctive therapy with platelet-rich fibrin (PRF) lysate-eyedrops compared with autologous serum eyedrops. MATERIALS AND METHODS: This study was a randomized double-blind controlled trial, which compared two groups of patients at Dr. Sardjito Hospital, Yogyakarta. A total of 42 patients (42 eyes) were divided into the control group (21 patients) and the intervention group (21 patients). All patients received antibacterial/antifu
View details →Negative / Null Result ReportOpen accessOphthalmology
Fiona J. Rowe, Laura Tremarco · 2010 · British and Irish Orthoptic Journal
Aim: To identify the effect of using different coloured bars on reading time for the bar reading task, along with an assessment of subject experience with different colour bars. Methods: Inclusion criteria were: visual acuity better than 0.5 logMAR, presence of binocular single vision, and ability to understand and perform bar reading. Measurements were taken of visual acuity, near point of convergence, interpupillary distance, Bagolini glasses and prism fusion range. Bar reading was timed and undertaken with and without five coloured bars for N5 and N12 print. Results: Forty subjects were rec
View details →Negative / Null Result ReportOpen accessOphthalmology
Lin Y, Luo S, Lu Q et al. · 2024 · Clinical Ophthalmology
Ye Lin, Shuke Luo, Qiang Lu, Xueke Pan Department of Ophthalmology, The Second People’s Hospital of Foshan, Foshan, Guangdong Province, People’s Republic of ChinaCorrespondence: Shuke Luo, Department of Ophthalmology, The Second People’s Hospital of Foshan, Foshan, Guangdong Province, 528000, People’s Republic of China, Tel +86 13679830510, Email 542377993@qq.comPurpose: To investigate the psychological changes in patients pre and post implantable collamer lens (ICL, EVO) implantation surgery in the posterior chamber.Patients and methods: Self-rating anxiety scale (SAS) and self-rating depress
View details →Negative / Null Result ReportOpen accessOphthalmology
Fabrizio Zeri, Mario De Cusatis, Luigi Lupelli et al. · 2016 · Journal of Optometry
Purpose: To investigate if the accuracy of intraocular pressure (IOP) measurements using rebound tonometry over disposable hydrogel (etafilcon A) contact lenses (CL) is affected by the positive power of the CLs. Methods: The experimental group comprised 26 subjects, (8 male, 18 female). IOP measurements were undertaken on the subjects’ right eyes in random order using a Rebound Tonometer (ICare). The CLs had powers of +2.00 D and +6.00 D. Measurements were taken over each contact lens and also before and after the CLs had been worn. Results: The IOP measure obtained with both CLs was significa
View details →Negative / Null Result ReportOpen accessOphthalmology
Anika Amritanand, Danica Lyngwa, Nimmy Thomas et al. · 2021 · TNOA Journal of Ophthalmic Science and Research
Purpose: The purpose of the study was to compare the efficacy of two vertically integrated teaching–learning methods, a peer-led ocular basic science workshop (OBSW) versus lecture by ophthalmology faculty, in enhancing the underlying basic science knowledge and examination skills of ophthalmic clinical tests among second clinical year medical students. Design: This was a prospective, interventional comparative study. Students were randomly assigned to peer-led OBSW and interactive lecture-based method of teaching by a faculty. Change in knowledge was assessed using pre and post multiple-choic
View details →Negative / Null Result ReportOpen accessOphthalmology
Yule Xu, Ao Rong, Wei Xu et al. · 2017 · BMC Ophthalmology
Abstract Background To compare the efficacy of intravitreal conbercept and ranibizumab in the treatment of diabetic macular edema (DME) in a real-life clinical practice. Methods This was a retrospective study. Among 62 Chinese patients with DME, 32 patients (36 eyes) received intravitreal conbercept (IVC) injections and 30 patients (32 eyes) received intravitreal ranibizumab (IVR) injections, once a month for 3 months followed by as needed therapy. All participants had at least 12 months of follow-up. We compared the changes in best-corrected visual acuity (BCVA) letter score and central retin
View details →Negative / Null Result ReportOpen accessOphthalmology
Mahmoud F. Abdelaal, Soheir M. Esmat, Mohamed A. Salah Eldein et al. · 2026 · Delta Journal of Ophthalmology
Purpose This study aimed to compare the anatomical and functional outcomes of pars plana vitrectomy (PPV), intravitreal ranibizumab (IVR), and intravitreal triamcinolone acetonide (IVTA) injection in chronic persistent diabetic macular edema (DME) with nontractional epiretinal membrane (NT-ERM). Patients and methods This is a randomized prospective study that included 52 patients having chronic DME with NT-ERM who were divided into three groups: PPV with internal limiting membrane peeling group, IVR group, and IVTA group. The patients were evaluated by optical coherence tomography angiography
View details →Negative / Null Result ReportOpen accessOphthalmology
Almeida DRP, Chin EK, Shah SS et al. · 2016 · Clinical Ophthalmology
David RP Almeida,1 Eric K Chin,2,3 Shaival S Shah,3 Benjamin Bakall,3 Karen M Gehrs,3 H Culver Boldt,3 Stephen R Russell,3 James C Folk,3 Vinit B Mahajan3,41VitreoRetinal Surgery PA, Minneapolis, MN, 2Retina Consultants of Southern California, Riverside, CA, 3Vitreoretinal Service, Department of Ophthalmology and Visual Sciences, 4Omics Laboratory, University of Iowa, Iowa City, IA, USABackground: The role of pars plana vitrectomy (PPV) for endophthalmitis has evolved over recent decades but the literature is lacking on comparisons between small-gauge and 20-gauge vitrectomy.Objective: To eval
View details →Negative / Null Result ReportOpen accessOphthalmology
Ahmed S Abdel-Wanes, Abelrahman G Salman, Azza M.A Said et al. · 2020 · Journal of the Egyptian Ophthalmological Society
Aim To determine the risk factors responsible for opaque bubble layer (OBL) formation in femtosecond-laser-assisted in situ keratomileusis (FSL-LASIK). Patients and methods A retrospective, comparative study was carried out from January 2015 to January 2017 in El-Watany Eye Hospital. Two hundred eyes who were eligible for FSL-laser-assisted in situ keratomileusis (FSL was done using FS200, wavelight, Germany SR/1025-1-380) were classified into two groups. Group I: the study group with OBL formation during surgery (100 eye) and group (II): the control group without OBL formation during surgery
View details →Negative / Null Result ReportOpen accessOphthalmology
Hao Jiang, Chao Xue, Yanlin Gao et al. · 2022 · Journal of Ophthalmology
Purpose. This study aimed to assess the application of a foldable capsular vitreous body (FCVB) in the treatment of severe ocular trauma and silicone oil (SO) dependent eyes. Methods. A retrospective analysis was performed on the clinical application of FCVB in the treatment of severe ocular trauma and SO dependent eyes. The results of best-corrected visual acuity and intraocular pressure (IOP) evaluation, B-scan ultrasonography or color Doppler ultrasonography, ultrasound biomicroscopy, and anterior segment photography were recorded during follow-up. A paired t-test was used to compare the di
View details →Negative / Null Result ReportOpen accessOphthalmology
Park HM, Ryu YU, Park IJ et al. · 2020 · Clinical Optometry
Hyung Min Park, 1 Young Uk Ryu, 2 In Jee Park, 1 Byoung Sun Chu 1 1School of Optometry and Vision Science, Daegu Catholic University, Gyeongsan-si, Republic of Korea; 2Department of Physical Therapy, Daegu Catholic University, Gyeongsan-si, Republic of KoreaCorrespondence: Byoung Sun ChuSchool of Optometry and Vision Science, Daegu Catholic University, 13-13 Hayang-ro, Hayang-eup, Gyeongsan-si, Gyeongsangbuk-do 38430, Republic of KoreaTel +82-53-850-2553Fax +82-53-359-6793Email bschu@cu.ac.krBackground: The purpose of this study is to investigate the effect of wearing neutral density (ND) filt
View details →Failed Experiment ReportOpen accessOphthalmology
Nereyda G. Martínez Suárez, Ileana A. Agramonte Centelles, Ileana A. Agramonte Centelles · 2008 · Revista Cubana de Oftalmología
OBJETIVO: Evaluar clínicamente de pacientes portadores de queratoconjuntivitis seca posterior a puntoplastia con la técnica de parche del punto lagrimal. MÉTODOS: Se realizó puntoplastia con la técnica de parche del punto lagrimal a 31 pacientes (62 ojos) portadores de queratoconjuntivitis seca grado 2, que acudieron a la consulta en el año 2006, y se utilizó conjuntiva autóloga en 16 pacientes (32 ojos) y mucosa labial, en 15 casos (30 ojos), y se les evaluó clínicamente al mes y a los tres meses de realizada la cirugía. RESULTADOS: En 26 pacientes se observó una mejoría subjetiva y objetiva
View details →Failed Experiment ReportOpen accessOphthalmology
Beatriz G. Armendariz, PhD, Ulrich F.O. Luhman, PhD, Brian Berger, MD et al. · 2025 · Ophthalmology Science
Objective: Nonproliferative diabetic retinopathy (NPDR) is a progressive disease that can lead to blindness. Current therapies for NPDR are invasive and not extensively used or accessible until the disease progresses, pointing to the need for an early noninvasive treatment. The objective of CANBERRA was to assess the safety, tolerability, and efficacy of oral administration of vicasinabin (RG7774) on the severity of diabetic retinopathy (DR) in participants with moderately severe to severe NPDR and good vision. Design: CANBERRA was a global, multicentric randomized, double-masked, parallel-gro
View details →Negative / Null Result ReportOpen accessOphthalmology
Sepehr Feizi, Mohammad Ali Javadi · 2019 · Journal of Ophthalmic & Vision Research
Purpose: To evaluate the effects of donor graft thickness on postoperative best spectacle-corrected visual acuity (BSCVA), refractive outcomes, endothelial cell density (ECD) and function, intraocular pressure (IOP), and postoperative complications after Descemet stripping automated endothelial keratoplasty (DSAEK). Methods: This retrospective, interventional case series enrolled 77 eyes of 64 patients who underwent DSAEK with or without simultaneous cataract surgery. Clinical outcomes, including BSCVA, refraction, keratometric astigmatism, IOP, and ECD were assessed at the final follow-up exa
View details →Negative / Null Result ReportOpen accessOphthalmology
Pear Pongsachareonnont, Nopphawan Uramphorn, Nuchanad Hounnaklang · 2018 · International Journal of Ophthalmology
AIM: To evaluate the association between visual impairment (VI) and mental health or social engagement in older adults living in rural Thailand. METHODS: Data for this cross-sectional study were drawn from a community survey conducted in 2015 in Saraburi Province, Thailand. Participants were 327 adults aged ≥50y. VI was assessed using presenting distance visual acuity. Mental health and social engagement were evaluated in face-to-face interviews using validated questionnaires. After determining the prevalence of VI and relevant sociodemographic characteristics, multivariate regression analysis
View details →Negative / Null Result ReportOpen accessOphthalmology
Ritu Mali, Smruti R. Priyadarshini, Srikant K. Sahu et al. · 2024 · Indian Journal of Ophthalmology
Purpose: To compare the visual outcomes, postoperative complications, and graft asymmetry between precut and manually dissected donor tissues for Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet stripping endothelial keratoplasty (DSEK) procedures, respectively. Methods: Seventy eyes of 70 patients undergoing DSEK/DSAEK at a tertiary eyecare center in eastern India were included in this prospective randomized control study. The 70 eyes were divided equally into two groups. Group A (n = 35) and Group B (n = 35) underwent DSEK and DSAEK procedures, respectively. the ope
View details →Negative / Null Result ReportOpen accessOphthalmology
Neoh Yee Ling, Tan Ee Ling, Syed Mudassar Imran Bukhari et al. · 2015 · Journal of Clinical Ophthalmology and Research
Introduction: Systemic diseases such as hypertension and diabetes mellitus (DM) have been identified as the risk factor for glaucoma. However, there is minimal knowledge on the impact of systemic diseases on severity of glaucoma. This study aimed to determine the association between systemic disease and systemic treatment and severity of glaucoma. Materials and Methods: A cross-sectional study was conducted involving 298 primary open-angle glaucoma (POAG; 169 high tension glaucoma (HTG) and 129 normal tension glaucoma (NTG)) patients presented at the eye clinic of two tertiary hospitals in Mal
View details →Negative / Null Result ReportOpen accessOphthalmology
Jia-Wen Li, Yi-Jian Li, Xi-Su Hu et al. · 2020 · International Journal of Ophthalmology
AIM: To assess the biosafety of a poly(acrylamide-co-sodium acrylate) hydrogel (PAH) as a 3D-printed intraocular lens (IOL) material. METHODS: The biosafety of PAH was first evaluated in vitro using human lens epithelial cells (LECs) and the ARPE19 cell line, and a cell counting kit-8 (CCK-8) assay was performed to investigate alterations in cell proliferation. A thin film of PAH and a conventional IOL were intraocularly implanted into the eyes of New Zealand white rabbits respectively, and a sham surgery served as control group. The anterior segment photographs, intraocular pressure (IOP), bl
View details →Negative / Null Result ReportOpen accessOphthalmology
Rini Saha, Gautam Singh Parmar, Ashok Kumar et al. · 2018 · Journal of Clinical Ophthalmology and Research
The aim of this study is to see the effect of transportation on corneoscleral buttons and to correlate them with the weight of ice used during transportation. This is a prospective cross-sectional study. A total of 119 corneas were graded using slit-lamp examination and specular microscopy before and after transportation. Groups were made based on the weight of ice used during transportation and the number of hours of storage in McCarey-Kaufman (MK) media. The overall median percentage of endothelial cell loss (ECL) was 11.33%. The median percentage of ECL was significantly more with <500 g of
View details →Negative / Null Result ReportOpen accessOphthalmology
Shunsuke Nakakura, Ryo Asaoka · 2022 · Eye and Vision
Abstract Background To evaluate the postoperative outcomes of initial trabeculectomy (Trab) and Ex-PRESS (EX) in terms of achieving an intraocular pressure (IOP) below 15 and 18 mmHg. Methods This study retrospectively analyzed 64 and 54 cases of Trab and EX, respectively, performed by the same surgeon with uniform management from April 2018 to March 2019. Surgical success was defined as 5 < IOP < 15 mmHg (criterion 1) and 5 < IOP < 18 mmHg (criterion 2) without additional glaucoma medication, needling, and bleb reconstruction 2 months after surgery. Survival analysis with Cox regression was p
View details →Negative / Null Result ReportOpen accessOphthalmology
Jemal Zeberga Shifa, Alemayehu Mekonnen Gezmu, Gezahen Negusse Ayane et al. · 2019 · The Pan-American Journal of Ophthalmology
A 22-year-old female patient was diagnosed to have HIV and treated by highly active antiretroviral therapy (HAART) since 2012 had developed a reduction of vision in both eyes secondary to cataract. The cataract was extracted from both eyes with no immediate postoperative complication. During follow-up, it was recognized that she had had bilateral Stage 3 macular hole in both eyes. The visual acuity in both eyes was 6/60 which did not improve with application of pinhole. Pars plana vitrectomy was done and sealed the macular hole in the left eye. The visual acuity remained the same in both eyes
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