Negative / Null Result ReportOpen accessGynecology and obstetrics
Min-Min Ou, Bi-Yun Liao, Xing-Hong Chen et al. · 2026 · European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Objective: To investigate the impact of laser-assisted hatching (LAH) on clinical outcomes in patients undergoing frozen-thawed embryo transfer (FET) cycles with embryos at different developmental stages. Methods: We conducted a retrospective analysis of 2208 patients who underwent vitrification-thawed FET at our reproductive center between October 2018 and June 2024, with some patients contributing multiple cycles. Patients were stratified by embryonic developmental stage into cleavage-stage FET (n = 793) and blastocyst-stage FET (n = 1415) groups. Each group was further subdivided based on p
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Wenwen Zhang, Huimin Tang, Qiucheng Jia et al. · 2024 · Clinical and Experimental Obstetrics & Gynecology
Background: To evaluate the effect of carbohydrate antigen 125 (CA125) and CA19-9 in distinguishing stage Ⅲ and Ⅳ endometriosis from benign and malignant tumors, and to explore whether it is related to the clinical features of the disease. Methods: In a retrospective cohort study based on clinical data from hospitals, a total of 183 patients with pathologically confirmed diagnosis of ovarian endometriotic cysts (OEC) in Hainan Provincial People’s Hospital for surgical treatment from January 2019 to August 2022 were selected as the case group, and a total of 276 cases of benign diseases, includ
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Bingqian Zhang, Lianbao Cao, Lingling Ding et al. · 2017 · Gynecology and Minimally Invasive Therapy
Objective: To evaluate the effects of different treatment methods for previous ectopic pregnancies (EP) on cryopreserved embryo transfer (CET) outcomes. Materials and Methods: This was a retrospective cohort study. Patients with EP histories were divided into four groups based on their previous EP treatments: Group 1—unilateral tubal removal; Group 2—bilateral tubal removal or unilateral tubal removal with contralateral tubal ligation; Group 3—conservative surgery group; and Group 4—conservative medication group. A total of 1333 women with previous histories of being admitted to the hospital f
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Guodong Zhang, Jijun Li, Jun Tang et al. · 2019 · BMC Pregnancy and Childbirth
Abstract Background The aim of this study was to assess the feasibility, safety and outcome of the embolization of non-gonadal collateral supplying gestational sac (GS) in addition to uterine artery embolization (UAE), followed by hysteroscopic curettage for the management of cesarean scar pregnancy (CSP). Methods A retrospective study was undertaken from January 2012 to September 2018 in 24 CSP patients in whom non-gonadal collaterals supplying GS were identified by arterial angiography performed immediately after UAE. These patients underwent attempt collateral embolization in addition to UA
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Lilian de Sá Paz Ramos, Jorge Villanova Biazús · 2024 · Revista Brasileira de Ginecologia e Obstetrícia
Abstract Objective: The purpose of this study was to compare postoperative pain between SF flap and serratus anterior muscle (SM) in direct-to-implant breast reconstruction. Methods: This is a prospective cohort study that included 53 women diagnosed with breast cancer who underwent mastectomy and one-stage implant-based breast reconstruction from January 2020 to March 2021. Twenty-nine patients (54.7%) had SF elevation, and 24 patients (45.3%) underwent SM elevation. We evaluated patient-reported early postoperative pain on the first day after surgery. Also, it was reported that all surgical
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Tom Marcelissen, Tanja Hüsch, Tiago Antunes-Lopes et al. · 2022 · Clinical and Experimental Obstetrics & Gynecology
Objectives: Minimally invasive sling procedures for the treatment of stress urinary incontinence has gained a topic of great interest for the last decades. However, postoperative storage symptoms after sling implantation or conventional surgical techniques are one of the most distressing complications which can significantly impair quality of life. The current review aims to focus on the development of storage symptoms after surgical treatment in comparison of different surgical techniques. Mechanism: A narrative review has been performed to identify literature reporting the incidence of stora
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Sepideh Mashayekh-Amiri, Fatemeh Bakouei, Sedighe Esmaeilzadeh et al. · 2019 · Caspian Journal of Reproductive Medicine
Background: The effect of individual sleep hygiene education on sleep quality components remains largely unknown during pregnancy. This study aimed to assess the effect of a short-term sleep hygiene education during prenatal care visits on pregnant women with poor sleep quality. Methods: A quasi-experimental study, designed as a pre- and post-test with a single group, was conducted on 32 pregnant woman with poor sleep quality. All the participants completed the Beck Depression Inventory (BDI), Perceived Stress Scale (PSS), and Pittsburgh Sleep Quality Index (PSQI). The women with good sleep qu
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Fariba Mousavi, Sakineh Mohammad-Alizadeh-Charandabi, Mojgan Mirgafourvand et al. · 2023 · Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān
Introduction: Early symptoms of menopause are very common and often very bothersome. Considering the increasing number of women experiencing these symptoms in the world and Iran, there is a growing need to use methods to reduce these symptoms. Therefore, this study was performed with aim to determine the effect of the combined herbal capsules (Menohelp) on reducing the early symptoms of menopause, number and intensity of hot flashes (primary outcomes), and improving sleep quality and quality of life (secondary outcomes) in menopausal women. Methods: In this double-blind trial in Tabriz, 100 wo
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Jingting Liu, Yijun Dong, Yawei Zhou et al. · 2024 · BMC Pregnancy and Childbirth
Abstract Background Observational epidemiological studies suggested that immunological dysregulation and inflammation play a significant role in the placental and renal dysfunction that leads to maternal hypertension. The immunophenotypes' possible causalities with hypertensive disease of pregnancy remain ambiguous. We performed two-sample Mendelian randomization (MR) analyses to comprehensively investigate the causal effect of immunophenotypes on hypertensive disorder of pregnancy (HDP). Methods The large-scale genome-wide association studies (GWASs) data on immunological traits was taken fro
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Ruiqi Wang, Yaqi Lin, Lixue Chen et al. · 2025 · Journal of Ovarian Research
Abstract Objective This multicenter retrospective study examines the impact of female COVID-19 infection on assisted reproductive technology (ART) outcomes, including clinical pregnancy rates, miscarriage rates, and live birth rates, and further evaluated potential influencing factors associated with these outcomes. Methods Our multicenter retrospective cohort study analyzed 10,140 cycles (2021–2023) from 10 Beijing ART centers, comparing 4,099 cycles from COVID-19-positive women with 6,041 age-matched (1:1.5) COVID-negative controls (pre-pandemic). Outcomes included pregnancy, miscarriage, an
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Fedora Ambrosetti, MD, Giovanni Grandi, MD, Elisabetta Petrella, MD et al. · 2023 · AJOG Global Reports
BACKGROUND: The use of epidural analgesia represents the gold standard for pain management during labor, but the influence of the use of epidural analgesia on delivery mode is not fully understood. OBJECTIVE: This study aimed to analyze the impact of epidural analgesia on the delivery mode, namely, cesarean delivery, vaginal delivery, and operative vaginal delivery rates, in Robson class 1 women. STUDY DESIGN: A retrospective cohort study was conducted on all Robson class 1 women who delivered from January 1, 2019, to December 31, 2019, in the University Hospital of Modena. The primary outcome
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Nafiseh Saghafi, Leila Pourali, Kiarash Ghazvini et al. · 2018 · International Journal of Reproductive BioMedicine
Background: One of the most important etiologies in pretermpremature rupture of membranes (PPROM) is cervical bacterial colonization. Objective: This study evaluated cervical bacterial colonization in women with PPROM and the pregnancy outcomes. Materials and Methods: In this cohort study, 200 pregnant women with PPROM at 27-37 wk of gestation who were admitted in an academic hospital of Mashhad University of Medical Sciences from March 2015 to July 2016 were studied. samples were obtained from endocervical canal for detection of routine bacteria and Gram staining. Also, we obtained one blood
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Divya Anantharaman, Aiswaryah Radhakrishnan, Vidhyalakshmi Anantharaman · 2023 · Journal of Pregnancy
Aim. Multisystemic physiological changes in pregnancy can result in tear film and refractive changes in the eye. We report dry eye prevalence in pregnant women using Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire. Methods. The SPEED questionnaire was self-administered cross-sectionally to 428 pregnant women (mean age: 26.8±4.4 years) with clinically confirmed pregnancy from two obstetric clinics in Chennai, India. Subjects with predisposing risk factors for dry eye were excluded from the study. Subjects were categorized as normal, moderate, and severe dry eye based on the SPE
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Baumann Gert, Gericke Christine, Mueller Simone et al. · 2010 · BMC Women's Health
Abstract Background Decreased levels of circulating bone marrow-derived progenitor cells have been associated with risk factors and cardiovascular diseases. Smoking is the most important modifiable risk factor for atherosclerosis in young women. The aim of this pilot study was to assess in healthy premenopausal women without other risk factors for cardiovascular disease the influence of nicotine abuse on the number of circulating progenitor cells in relation to endothelial function. Methods The number of endothelial progenitor cells, measured as colony-forming units in a cell-culture assay (EP
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Yangyang Zhang, Yang Xu, Jiao Yu et al. · 2023 · Journal of Ovarian Research
Abstract Background A premature luteinizing hormone (LH) surge refers to an endogenous LH peak that occurs before follicle maturation or human chorionic gonadotropin injection in the process of controlled ovarian hyperstimulation. The effect of premature LH surge on pregnancy outcomes in fresh embryo transfer cycles is still controversial. The aim of this study was to explore the effect of a premature LH surge without elevated progesterone levels on the cumulative pregnancy rate (CPR) and cumulative live birth rate (CLBR) of patients during a flexible GnRH antagonist protocol. Methods A total
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Yahya Irwanto · 2012 · Indonesian Journal of Obstetrics and Gynecology
Objective: To know whether the expression of Fas Ligand has correlation with incidene of metastasis of pelvic lymph node and lymph-vascular stromal invasion (LVSI). Methods: All patients diagnosed of cervical cancer stage IB or IIA who underwent radical hysterectomy in Dr. Cipto Mangunkusumo Central General Hospital from January 2008 until December 2009 were included in analytic cross sectional study. We tested expression of Fas Ligand in cervical cancer specimen by immunohystochemistry with monoclonal antibody. The expression of Fas Ligand was compared between the group of patients with a pos
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Janace J. Gifford, Jenna R. Pluchino, Rebecca Della Valle et al. · 2021 · Frontiers in Global Women's Health
Purpose: The purpose of this study was to assess the association between various risk factors with postpartum depression severity using a large dataset that included variables such as previous mental health status, social factors, societal factors, health care access, and other state-wide or region-specific variables.Methods: We obtained the most recently available (2016–2017) dataset from the Pregnancy Risk Assessment Monitoring System (PRAMS), which is a dataset compiled by the Centers for Disease Control (CDC) that collects state-specific, population-based data on maternal attitudes and exp
View details →Replication FailureOpen accessGynecology and obstetrics
Fereshteh Vaziri Nezamdoust, Hossein Hadinedoushan, Nasrin Ghasemi · 2023 · International Journal of Reproductive BioMedicine
Abstract Background: A large proportion of cases of recurrent pregnancy loss (RPL) are associated with immunological factors. Objective: This study investigated the association between single nucleotide polymorphisms of cytotoxic T-lymphocyte-associated protein (CTLA)-4 gene in women with a history of RPL compared to healthy women. Materials and Methods: A case-control study was performed on 2 groups consisting of 120 healthy women with no history of abortion and at least one delivery (control) and 120 women with a history of 2 or more primary RPLs (case). In addition, 5 mL of peripheral blood
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Toar A Kumaat, Maria F T Loho, Eddy Suparman · 2017 · Indonesian Journal of Obstetrics and Gynecology
Objective: To assess paramedic menopausal symptoms on the inpatient unit and outpatient unit. Methods: This was a cross sectional study. Data collect by fill the questioner, the questioner fill by menopausal paramedic on Prof. Dr. R. D. Kandou Manado Hospital from October 2016 to January 2017. Data were analyzed using SPSS 22.0 for Windows. Results: Of 60 paramedics, 30 were divided to inpatient unit and the other 30 were divided to outpatient unit. By the menopause rating scale, somatic and urogenital complaint in statistical test have no significant differences. Psychology complaint with a m
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