Negative / Null Result ReportOpen accessPsychiatry
Roxoliana Tsisar, Kristen E. Zentner, Katherine Shettell et al. · 2026 · Frontiers in Psychiatry
BackgroundPsychoeducation for families of young adults with psychosis is an evidence-based intervention that alleviates carer burden. The implementation of programming is limited, leaving family carers shouldering a heavy burden without appropriate support.ObjectiveThis pre-post longitudinal pilot study evaluated the preliminary outcomes of a psychoeducational group intervention for family carers of young adults with psychosis, aimed at building skills and reducing carer burden to support recovery in their loved ones.MethodsThe intervention, co-developed and co-facilitated by healthcare profes
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Stanley N. Caroff, Fan Mu, Rajeev Ayyagari et al. · 2018 · BMC Psychiatry
Abstract Background Data are limited on the benefits and risks of dose reduction in managing side effects associated with antipsychotic treatment. As an example, antipsychotic dose reduction has been recommended in the management of tardive dyskinesia (TD), yet the benefits of lowering doses are not well studied. However, stable maintenance treatment is essential to prevent deterioration and relapse in schizophrenia. Methods A retrospective cohort study was conducted to analyze the healthcare burden of antipsychotic dose reduction in patients with schizophrenia. Medical claims from six US stat
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S. Javed, R. K. Gaur, A. Ibrahim et al. · 2017 · Sri Lanka Journal of Psychiatry
Background Dementia is a common, disabling disorder of the elderly. With the steady growth in the older population, the rate of dementia is expected to increase two fold by 2030 and three fold by 2050. Dementia of Alzheimer Type (DAT) and vascular dementia (VD) are among the most common types of dementia. Behavioral and psychological symptoms of dementia (BPSD) are associated with increased patient morbidity and carer burden. Aims The objective of this study was to compare symptoms of BPSD in patients with DAT and VD and to explore the correlates of BPSD in patients with DAT and VD. Methods Pe
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Sema Şimşek, Hasan Atak · 2021 · Psikiyatride Güncel Yaklaşımlar
In this study, the effect of 12-18 Age Family Education Program (AEP) on family functions was examined in a quasi-experimental study. The families in the experiment and control groups of the study were selected by purposeful sampling method. Self-Assessment Scale, The Family Assessment Device (FAD) and Me as a Parent Scale (MPS) were used as pretest-posttest data collection tools. A 14-session Family Education Program was carried out in the experimental group. No study was conducted with the control group. In the experimental group, it was observed that there was a significant difference betwe
View details →Negative / Null Result ReportOpen accessPsychiatry
Jonas Weijers, Jonas Weijers, Wolfgang Viechtbauer et al. · 2018 · Frontiers in Psychiatry
A previous study observed that reported childhood abuse moderated psychotic and emotional reactivity to stress among patients with non-affective psychotic disorder. However, that study used a type of analysis unsuited for skewed data. This study aimed (1) to replicate the study and (2) to examine whether we would obtain similar results using a statistical approach better suited to skewed data. Fifty-nine patients with non-affective psychotic disorder were examined for up to 6 days using an intensive diary method to assess levels of negative affect, psychosis, and daily-life stress. A mixed-lin
View details →Negative / Null Result ReportOpen accessPsychiatry
Esther-Sevil Eigl, Laura Krystin Urban-Ferreira, Manuel Schabus et al. · 2023 · Frontiers in Psychiatry
BackgroundApproximately one-third of the healthy population suffer from sleep problems, but only a small proportion of those affected receive professional help. Therefore, there is an urgent need for easily accessible, affordable, and efficacious sleep interventions.ObjectiveA randomized controlled study was conducted to investigate the efficacy of a low-threshold sleep intervention consisting of either (i) sleep data feedback plus sleep education or (ii) sleep data feedback alone in comparison with (iii) no intervention.Material and methodsA total of 100 employees of the University of Salzbur
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Fatemeh Asgharian Asl, Sajjad Abbaszade, Sajjad Abbaszade et al. · 2024 · Frontiers in Psychiatry
BackgroundExciting left DLPFC activity with high frequency and inhibiting right DLPFC with low frequency repetitive transcranial magnetic stimulation (rTMS) has shown antidepressant effects in major depressive disorder (MDD) and executive functions. However, few studies have directly compared unilateral and bilateral protocols.MethodsForty-seven individuals with treatment-resistant MDD underwent 10 sessions of rTMS over left DLPFC (20 Hz), bilateral DLPFC (left 20 Hz, right 1 Hz), or sham stimulation. Outcomes were depression (Beck Depression Inventory-II), visual-spatial memory (Corsi Block T
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Jiaojiao Zhou, Xu Chen, Le Xiao et al. · 2021 · Frontiers in Psychiatry
Background: Insomnia is a common clinical manifestation in patients with depression. Insomnia is not only a depression symptom but also an independent risk factor for recurrence. Cordyceps militaris (C. militaris) is thought to have the potential to treat insomnia. This study aimed to examine the efficacy and safety of duloxetine with C. militaris in improving sleep symptoms in patients with depression.Methods: This study was a single-center, randomized, double-blind, placebo-controlled study that recruited outpatients admitted to Beijing Anding hospital from January 2018 to January 2019. Majo
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Michael Pascal Hengartner, Silvia ePassalacqua, Gisela eHeim et al. · 2016 · Frontiers in Psychiatry
Purpose: To evaluate the efficacy of a post-discharge intervention for psychiatric inpatients aimed at preventing hospital readmissions and at improving patients’ mental health and psychosocial functioning. Methods: RCT using parallel group block randomisation including 151 patients with ≤3 hospitalisations within the last three years, a GAF score ≤60, and aged 18–64 years, assessed at two psychiatric hospitals from the canton of Zurich, Switzerland, between September 2011 and February 2014. Primary outcomes were rate and duration of rehospitalisation; secondary outcomes were mental health and
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Nadine Farnes, Nadine Farnes, Henrik B. Jacobsen et al. · 2024 · Frontiers in Psychiatry
IntroductionDeep rTMS is an increasingly popular noninvasive brain stimulation technique which has shown promise for treating cognitive impairments. However, few studies have investigated the cognitive effects it could exert in patients with chronic peripheral neuropathic pain. Therefore, we aimed to assess the effects of deep rTMS on executive functioning in patients with peripheral neuropathic pain, in a randomized, double-blind crossover trial.MethodsIn total, 17 patients were randomly assigned to receive both active and sham deep H-coil rTMS targeting the primary motor cortex. Each treatme
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ّForough Farshidmanesh, Hosein Davoudi, Hasan Heidari et al. · 2019 · Taḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: Many women begin their marital life with high intimate relationships, but with time, these intimate relationships are becoming less and more difficult, and it is just when then couple burnout has begun. The purpose of this study was to comparison of the effectiveness of mindfulness education and Emotional Focused Therapy (EFT) on couple intimacy, commitment and happiness women with couple burnout. Methods and Materials: The semi-experimental study was performed as pretest-posttest with a control group. The population included all women with couple burnout who was referred t
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Meret Sophie Wallimann, Katharina Beck, David Cyrill Lätsch · 2026 · European Journal of Psychotraumatology
Background: Psychological maltreatment is linked to negative developmental outcomes in adolescents. It includes psychological abuse (PA) and psychological neglect (PN), which are commonly studied as a pair. This study applied the dimensional model of adversity and psychopathology (DMAP), which conceptualises abuse as a threatening experience involving harm or the threat of harm that primarily impairs social-emotional processing, such as emotion regulation, while it views neglect as deprivation or absence of parental care that predominantly affects cognitive functioning, such as working memory.
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U. Raja, A. Misra, N. Kar · 2024 · European Psychiatry
Introduction The Crisis and Home Treatment Teams (CRHT) in psychiatry manages patients with risk to self and others in the community. The number of patents under CRHT who attempt or die of suicide is high in the UK (Hunt et al BJPsych Bull. 2016;40:172-4). The CRHT is an option to help support patients in managing their risk using various interventions and also aim to prevent admission to acute psychiatric wards where possible. Objectives We intended to study the change in risk to self and others and the factors associated with it during the intervention from a CRHT taking care of adult patien
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Junjun Liu, Junjun Liu, Junjun Liu et al. · 2023 · Frontiers in Psychiatry
ObjectiveTriglyceride glucose (TyG) index has been suggested as an alternative indicator of insulin resistance (IR); however, the association between TyG index and suicide attempts (SA) in major depressive disorder (MDD) is unclear. The aim of this study was to investigate the relationship between TyG index and SA in Chinese patients with first-episode drug-naïve (FEDN) MDD.MethodsThis cross-sectional study enrolled 1,718 patients with FEDN MDD aged 34.9 ± 12.4 years from the First Hospital of Shanxi Medical University (Taiyuan, Shanxi Province, China) from September 2016 to December 2018. Mul
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Ahmed Kamil Toman, Ahmed Kamil Toman, Ahmed Kamil Toman et al. · 2025 · Frontiers in Psychiatry
IntroductionCo-occurring conditions are common in children with autism spectrum disorder (ASD) and have important negative impacts on the children and their families. For Iraqi children, local healthcare systems tend to place more emphasis on the management of ASD itself while neglecting co-occurring conditions.ObjectivesThis study aims to investigate the prevalence, characteristics, and potential risk factors of co-occurring epilepsy, sleep, and weight issues among Iraqi children with ASD.MethodsA multicenter cross-sectional study was conducted from January 24 to August 7, 2024, including chi
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Manik Changoji Bhise, Arun Vishwambhar Marwale, Ashish Chandrakantrao Mohide et al. · 2019 · Annals of Indian Psychiatry
Background: Survivors of suicide experience psychological distress for years after suicide. In India, farmers' suicide survivors are special group, with unique set of stressors. There are very few studies examining this group in India. The objective was to assess psychological distress and its correlates in survivors of farmers' suicides. Methods: This was a cross-sectional study from two districts of Marathwada region of Maharashtra. A predesigned and pretested semi-structured questionnaire to assess sociodemographic variables was used. Self-reporting questionnaire-20 was administered to eval
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O. Elleuch, M. Maalej, W. Guidara et al. · 2023 · European Psychiatry
Introduction The pathophysiology of bipolar disorder (BD) is complex and remains uncertain to this day. Several hypotheses have been suggested, including the involvement of inflammatory mechanisms in its pathogenesis and in eventual cognitive impairment. C-reactive protein (CRP) is one of the most commonly used inflammatory markers. High-sensitivity CRP (hs- CRP) is a more sensitive marker. Objectives We aimed to examine hs-CRP levels in patients with BD, and to investigate its relationship with cognitive functions. Methods We conducted a cross-sectional study between June 2016 and July 2018 o
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Subodh Kumar, Divye Kartikey, Jayeeta Biswas · 2022 · Indian Journal of Private Psychiatry
Background: The deadly second wave of coronavirus disease-2019 (COVID-19) pandemic swept through the whole of India during the month of April–May 2021. Restrictions like lockdowns and social distancing impacted the normal functioning of life. It is in this backdrop that we need to understand the perceived stress and quality of life among people. Aim and objective: The aim and objective of this study was to evaluate and study the relationship between perceived stress and quality of life among adults living in Delhi NCR, during the second wave of the COVID-19 pandemic. Materials and methods: A 1
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