Effects of N-acetylcysteine on aging cell and obesity complications in obese adults: a randomized, double-blind clinical trial
Mohammad Hassan Sohouli; Ghazaleh Eslamian; Nasser Malekpour Alamdari; Maryam Abbasi; Sepideh Fazeli Taherian; Diba Behtaj; Hamid Zand · 2023 · Frontiers in Nutrition
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BackgroundWe decided to conduct this study with the aim of investigating the effects of N-Acetylcysteine (NAC) on obesity complications and senescence of visceral adipose tissue in obese adults.Methods and analysisThe present study was conducted as a randomized clinical trial (RCT) (Clinical trial registry number: IRCT20220727055563N1) on 40 obese adults candidates for bariatric surgery, who were randomly assigned to receive 600 mg of NAC (n = 20) or placebo as a control (n = 20) for 4 weeks. During bariatric surgery, visceral adipose tissue was used to examine gene expression and senescence c
Abstract by Mohammad Hassan Sohouli; Ghazaleh Eslamian; Nasser Malekpour Alamdari; Maryam Abbasi; Sepideh Fazeli Taherian; Diba Behtaj; Hamid Zand, Frontiers in Nutrition (2023) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.3389/fnut.2023.1237869