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Negative / Null Result ReportOpen accessSurgery

Photogrammetric Facial Analysis of Attractive Celebrities Using the Glabella for Planning Rhinoplasty and Analyzing Surgical Outcomes

Cheol Woo Park, Myung Ju Lee, Yun Ik Jung · 2018 · Archives of Aesthetic Plastic Surgery

Background Identifying problems and making a surgical plan through a preoperative analysis is important in facial aesthetic surgery. Thus, popular conceptions of an attractive face must be analyzed beforehand. The landmarks used as reference points may change after rhinoplasty, resulting in errors in the prediction and assessment of outcomes. To reduce such errors, it is advantageous to use reference points and landmarks that are subject to minimal variation. This study measured and analyzed landmarks with little preoperative and postoperative variation in rhinoplasty, and established appropri

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Negative / Null Result ReportOpen accessSurgery

Modified overlap SMAS flap in the treatment of facial depression after resection of benign parotid lesions

Zhen Yu, Wenxing Xun, Pan Ren et al. · 2025 · World Journal of Surgical Oncology

Abstract Objective The purpose of our study was to evaluate the clinical effect of a facelift combined with a modified overlapping superficial musculoaponeurotic system (SMAS) flap for repairing facial depression caused by the resection of benign parotid lesions. Methods This retrospective, non-randomized observational study included 87 patients diagnosed with benign parotid tumors who underwent surgical treatment between June 2014 and September 2023. All patients were treated in our department or by the same surgical team after institutional transfer. All patients received surgery via a stand

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Negative / Null Result ReportOpen accessSurgery

Risk factors associated with secondary displacement in fractures of the humeral greater tuberosity

Qing-Quan Chen, Qing-Quan Chen, Han-Lin Chen et al. · 2025 · Frontiers in Surgery

BackgroundThe incidence of secondary displacement in fractures of the greater tuberosity of the humerus remains high, irrespective of whether conservative or surgical treatment is administered. However, the specific risk factors contributing to secondary displacement of the greater tuberosity of the humerus have not been previously reported. The primary objective of this study was to analyze the risk factors associated with secondary displacement of the greater tuberosity of the humerus and to summarize corresponding guidelines for clinical diagnosis and treatment.MethodsA retrospective analys

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Negative / Null Result ReportOpen accessSurgery

Fine versus Sclerotic Trabecular Bone Remodeling/Restructure: A Refined Radiographic Predictor for Long-Term Segment Stability After Posterior Lumbar Interbody Fusion

Yasuhiro Nagatani MD, Naoki Segi MD, Sadayuki Ito MD et al. · 2026 · Global Spine Journal

Study Design Retrospective cohort study. Objectives Successful bone fusion is crucial for favorable posterior lumbar interbody fusion (PLIF) outcomes. While trabecular bone remodeling (TBR) indicates osseointegration, its interpretation remains uncertain. This study aimed to clarify the clinical significance of distinct TBR types—fine TBR (fTBR) and sclerotic TBR (sTBR)—as seen on computed tomography (CT) scans and to evaluate their predictive value for segment stabilization and complete bone fusion and their relationship with interbody cage materials. Methods Seventy-one patients who underwen

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Negative / Null Result ReportOpen accessSurgery

Study of the therapeutic strategy to improve survival outcomes from the perspective of perioperative conditions in elderly gastric cancer patients: a propensity score-matched analysis

Eiji Nomura, Takatoshi Seki, Kentaro Yatabe et al. · 2024 · World Journal of Surgical Oncology

Abstract Background Elderly gastric cancer patients (EGCPs) require treatment according to not just the stage of their cancer, but also to their general condition and organ function, and rather than full treatment, the appropriate amount of treatment is necessary. Methods A total of 425 patients who underwent gastrectomy for primary gastric cancer in our institution between April 2013 and March 2020 were classified by age into two groups: elderly patients (EP, age ≥ 80 years, n = 89); and younger patients (YP, age < 80 years, n = 336). The preoperative, intraoperative, and postoperative condit

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Negative / Null Result ReportOpen accessSurgery

Subclinical cardiac dysfunction detected by speckle-tracking echocardiography in patients with liver cirrhosis undergoing liver transplantation

Nguyen Tai Thu, Pham Dang Hai, Nguyen Thi Kieu Ly et al. · 2024 · Egyptian Liver Journal

Abstract Background Cirrhosis is associated with chronic cardiovascular dysfunction termed cirrhotic cardiomyopathy (CCM), characterized by myocardial hypertrophy and diastolic dysfunction. Detecting early cardiac changes is crucial, especially in patients undergoing liver transplantation. Objective: This study aims to evaluate left ventricular systolic function in cirrhotic patients undergoing liver transplantation using speckle-tracking echocardiography. Methods A prospective observational study was conducted involving 54 cirrhotic patients who underwent liver transplantation, along with 28

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Negative / Null Result ReportOpen accessSurgery

Polypropylene and polypropylene/polyglecaprone (Ultrapro(r)) meshes in the repair of incisional hernia in rats

Edivaldo Massazo Utiyama, Maria Beatriz Sartor de Faria Rosa, Marina de Paula Andres et al. · 2015 · Acta Cirúrgica Brasileira

PURPOSE: To compare the inflammatory response of three different meshes on abdominal hernia repair in an experimental model of incisional hernia.METHODS: Median fascial incision and skin synthesis was performed on 30 Wistar rats. After 21 days, abdominal hernia developed was corrected as follows: 1) No mesh; 2) Polypropylene mesh; and, 3) Ultrapro(r) mesh. After 21 days, the mesh and surrounding tissue were submitted to macroscopic (presence of adhesions, mesh retraction), microscopic analysis to identify and quantify the inflammatory and fibrotic response using a score based on a predefined s

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Negative / Null Result ReportOpen accessSurgery

The value of blood and urine metabolomics in differential diagnosis of cholestasis in infants

Samah Abdelfatah Eshiaty, Shimaa Abdelsattar, Dina Sweed et al. · 2023 · Egyptian Liver Journal

Abstract Background Early detection of biliary atresia (BA) is a great challenge providing the main useful way to improve its clinical consequence. Promising metabolomics provides an effective method for determining innovative biomarkers and biochemical ways for improving early diagnosis. This study aimed to determine the benefit of serum and urinary potential bile acid metabolites in the differentiation of BA from non-biliary atresia (non-BA) cases using tandem mass spectrometry (MS/MS). Fourteen bile acids metabolites were measured quantitively by MS/MS in serum and urine samples from 102 ch

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Negative / Null Result ReportOpen accessSurgery

A compara tive analysis of short-term patient outcomes after laparoscop ic versus robotic rectal surgery

Chi Zhaocheng · 2022 · 结直肠肛门外科

[Background] The popularity of robot-assisted colorectal surgery has risen over recent years; however, patient-related advantages over laparoscopic surgery remain uncertain. [Objective] The goal of this study was to compare short-term patient outcomes following robotic and laparoscopic partial or complete rectal resections. [Design] This was a retrospective cohort study. [Settings] The study was conducted at 5 large tertiary care Kaiser Permanente medical centers across Southern California. [Patients] There were 863 consecutive robotic and laparoscopic pelvic rectal surgeries, including low an

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Negative / Null Result ReportOpen accessSurgery

Survival following orbital exenteration at a tertiary brazilian hospital

Juliana Mika Kato, Fabricio Lopes da Fonseca, Suzana Matayoshi · Revista do Colégio Brasileiro de Cirurgiões

Objective: to analyze the epidemiology, clinical features and survival rate of patients undergoing orbital exenteration (OE) in a tertiary referral hospital. Methods : we conducted a retrospective study of all patients undergoing OE at the Hospital das Clínicas, FMUSP between January 2007 and December 2012. We collected data records related to gender, age, origin, length of stay, duration of the disease, other treatments related to the disease, number of procedures outside of the face related to the disease, follow-up and histological diagnosis. Results : we treated 37 patients in the study pe

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Negative / Null Result ReportOpen accessSurgery

Monitoring of Intracranial Pressure During Intracranial Endoscopy

Rajeev Kumar, Anita Malik, Monika Kohli et al. · 2013 · Archives of Clinical and Experimental Surgery

Background: Intracranial endoscopy is a minimum invasive procedure, which reduces trauma to the brain, is cost-effective, and carries a shortened hospital stay with an improved postoperative outcome. Objective: To monitor intracranial pressure changes during intracranial endoscopy among children and adults under general anesthesia/sedation, and to compare the intracranial pressure changes between children and adults receiving general anesthesia and among adults receiving general anesthesia and sedation. Methods: The present cross-sectional study was conducted in one of the tertiary care hospit

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Negative / Null Result ReportOpen accessSurgery

Comparison of the cost analysis in total hip arthroplasty of anterior versus posterior approaches: A propensity score-matched cohort study in a single center

Tetsuya Tachibana, Hiroki Katagiri, Hideyuki Koga et al. · 2023 · Journal of Joint Surgery and Research

Purpose: The advantage of total hip arthroplasty (THA) in an anterior approach compared with a posterior approach in terms of early postoperative pain and function and lowering dislocation risks is controversial. This study aimed to identify whether THA using the anterior approach lowers costs compared with the posterior approach. Methods: We identified 294 patients who underwent primary THA and compared the cost of total inpatient stay, inpatient length of stay (LOS), cost of operating room, and the rates of discharged patients, complications, and reoperation between the anterior and posterio

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Negative / Null Result ReportOpen accessSurgery

Outcomes in patients with aortic stenosis and severely reduced ejection fraction following surgical aortic valve replacement and transcatheter aortic valve replacement

Eric R. Bain, Bistees George, Syed H. Jafri et al. · 2024 · Journal of Cardiothoracic Surgery

Abstract Background Patients with severe aortic stenosis (AS) and left ventricular (LV) dysfunction demonstrate improvement in left ventricular injection fraction (LVEF) after aortic valve replacement (AVR). The timing and magnitude of recovery in patients with very low LVEF (≤ 25%) in surgical or transcatheter AVR is not well studied. Objective Determine clinical outcomes following transcatheter aortic valve replacement (TAVR) and surgical aortic valve repair (SAVR) in the subset of patients with severely reduced EF ≤ 25%. Methods Single-center, retrospective study with primary endpoint of LV

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Negative / Null Result ReportOpen accessSurgery

Débito cardíaco e fração de ejeção fetal por meio do spatio-temporal image correlation (STIC): comparação entre fetos masculinos e femininos Fetal cardiac output and ejection fraction by spatio-temporal image correlation (STIC): comparison between male and female fetuses

Christiane Simioni, Edward Araujo Júnior, Wellington P. Martins et al. · 2012 · Brazilian Journal of Cardiovascular Surgery

OBJETIVO: Comparar do débito cardíaco (DC) e a fração de ejeção (FE) do coração de fetos masculinos e femininos obtidos por meio da ultrassonografia tridimensional, utilizando o spatio-temporal image correlation (STIC). MÉTODOS: Realizou-se um estudo de corte transversal com 216 fetos normais, entre 20 a 34 semanas de gestação, sendo 108 masculinos e 108 femininos. Os volumes ventriculares no final da sístole e diástole foram obtidos por meio do STIC, sendo as avaliações volumétricas realizadas pelo virtual organ computer-aided analysis (VOCAL) com rotação de 30º. Para o cálculo do DC utilizou

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Negative / Null Result ReportOpen accessSurgery

Correlation between Spinal Coronal Profile and Proximal Femur Bone Mineral Density in Adolescent Idiopathic Scoliosis

Ali Andalib · 2016 · Global Spine Journal

Introduction Although Adolescent Idiopathic Scoliosis patients have lower Bone Mineral Density (BMD) but relationship between BMD and curve pattern, intensity of curve, or its progress in these patients is controversial. Some studies have shown a significant difference between left and right proximal femur BMDs in AIS patients. Since the curve pattern relationship with density of bilateral proximal femur has not been identified, this study aims to investigate the relationship between Spinal Coronal Profile and differences in BMD on either sides of proximal femur in patients with AIS. Material

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Negative / Null Result ReportOpen accessSurgery

Evaluating Artificial Intelligence’s Role in Developing Research Questions in Head and Neck Reconstruction

Sebastian Holm, MD, Mario Zambrana, MD, Juan E. Berner, MD, PhD et al. · 2025 · Plastic and Reconstructive Surgery, Global Open

Summary:. Generative artificial intelligence (AI) large language models are an emerging technology, with ChatGPT and Gemini being 2 well-known examples. The current literature discusses clinical applications and limitations of AI, but its role in research has not yet been extensively evaluated. This study aimed to assess the role of ChatGPT and Gemini in developing novel and clinically relevant research ideas (RIs) for systematic reviews (SRs) in head and neck reconstruction. ChatGPT and Gemini were prompted to provide 10 novel and clinically relevant RIs for SRs in the following domains: head

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Negative / Null Result ReportOpen accessSurgery

Is Anti-platelet Treatment Necessary for Penile Mondor’s Disease?

Ahmet Murat Bayraktar, Muhammet İrfan Dönmez · 2019 · Journal of Urological Surgery

Objective:The aim of this study was to determine if anti-platelet treatment would have any effect on the rate and duration of resolution in penile Mondor’s disease.Materials and Methods:A retrospective review of patients diagnosed with Mondor’s disease between 2014 and 2018 was conducted. The patients were divided into two groups with regard to anti-platelet treatment. Age, initial symptom, medications [short-term fluoroquinolone antibiotics (Ab) ± low-dose acetyl salicylic acid (ASA)], and erectile function scores were evaluated. Moreover, ultrasonographic findings (location and length of thr

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Negative / Null Result ReportOpen accessSurgery

Radiofrequency Ablation for 110 Malignant Liver Tumours: Preliminary Results on Percutaneous and Surgical Approaches

J. Wong, K.F. Lee, P.S.F. Lee et al. · 2009 · Asian Journal of Surgery

Radiofrequency ablation (RFA) has been widely applied for the treatment of hepatocellular carcinoma and liver metastases. The reported mortality and morbidity rates are low. The aim of this study is to evaluate the safety and efficacy of RFA, and compare the results performed percutaneously versus surgically. Patients and Methods: From 2003 to 2006, 79 patients with hepatic malignancies (59 hepatocellular carcinoma, 20 liver metastases) with a total of 110 lesions underwent RFA in our centre. Post-ablation assessment by CT scan was performed in all patients at 1-, 3- and 6-month intervals. Pos

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Negative / Null Result ReportOpen accessSurgery

Investigating the effect of serum level of uric acid on the immunogenicity of hepatitis B vaccination in dialysis patients

Nasibe Golestani, Najmeh Shamspour, Jalal Azmandian et al. · 2024 · Egyptian Liver Journal

Abstract Introduction HBV infection is a significant concern in dialysis patients, influenced by various factors. This study aims to investigate the impact of serum uric acid levels on the immunogenicity of hepatitis Bvaccination in dialysis patients. Method A cross-sectional study was conducted, involving 125 hemodialysis patients. Prior to dialysis, assessments were made for uric acid, vitamin D, HBsAg, andHBsAb. Patients were divided into two groups based on uric acid levels: high level (≥ 6.5 mg/dl) and low level ( 10). In patients with low uric acid, 1 (7.7%) had low HBsAb and 12 (92.3%)

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Negative / Null Result ReportOpen accessSurgery

Clinical Relevance of Preoperative Neutrophil to Lymphocyte and Platelet to Lymphocyte Ratio in Renal Cell Carcinoma

Engin Kölükçü, Şahin Kılıç, Doğan Atılgan et al. · 2018 · Journal of Urological Surgery

Objective:The association of preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with postoperative tumor stage and Fuhrman nuclear grade was investigated in patients with renal cell carcinoma (RCC).Materials and Methods:Data of 123 patients, who were operated due to RCC, in our clinic was analysed. NLR and PLR were evaluated in patients who were classified according to tumor stage (T1 and T2 low stage, T3 and T4 high stage) and Fuhrman nuclear grade (grade 1 and 2 low-grade, grade 3 and 4 high-grade). NLR and PLR were compared using Levene’s test between t

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Negative / Null Result ReportOpen accessSurgery

Our midterm restenosis results using patch angioplasty closure versus primary closure in patients undergoing carotid endarterectomy: A comparative study

Taner İyigun, Mugisha Kyaruzi, Barış Timur et al. · 2019 · Turkish Journal of Vascular Surgery

Objectives: This study aims to compare midterm results of patch angioplasty with primary closure techniques in patients undergoing carotid endarterectomy (CEA) in terms of restenosis. Patients and methods: This prospective, single-center, randomized study included a total of 137 patients (42 females, 95 males; mean age 64.4±8.8 years; range 36 to 86 years) who underwent CEA between January 2010 and October 2015. The patients were divided into two groups: the patch angioplasty group (n=70) and the primary closure group (n=67). The mean follow-up was 2-7 years. Carotid computed tomography angiog

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Negative / Null Result ReportOpen accessSurgery

Association of Charlson Comorbidity Index and Charlson Fracture Index With Surgical Complications in Distal Radius Fractures: A Retrospective Review

Amber M. Parker, MD, Nicholas Genovese, MD, Alexy Ilchuk, BS et al. · 2026 · Journal of Hand Surgery Global Online

Purpose: To assess and compare the associative value of comorbidity fracture-specific index (CFI) versus the Charlson comorbidity index (CCI) in identifying patients at risk for early complications after open reduction and internal fixation (ORIF) of distal radius fractures (DRFs). Methods: We performed a single-center retrospective cohort study including patients ≥40 years who underwent ORIF for closed DRF using a volar locking plate with a minimum of 1 year follow-up. CCI and CFI scores were calculated based on comorbidities over the prior 15 years. The primary outcome was 90-day postoperati

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Negative / Null Result ReportOpen accessSurgery

Use of Botulinum Toxin for the Treatment of Raynaud Phenomenon

Manasa H. Kalluri, BS, Armin Edalatpour, MD, Allison J. Seitz, MD et al. · 2026 · Plastic and Reconstructive Surgery, Global Open

Summary:. Raynaud phenomenon (RP) is a vasospastic condition of the digital arteries that can cause pain, skin color changes, and functional limitations. Although botulinum toxin is not currently Food and Drug Administration–approved for the treatment of RP, it has been used in refractory RP and has generally been found to be well tolerated. At our institution, incobotulinumtoxinA (Xeomin) and abobotulinumtoxinA (Dysport) are commonly used. Here, we report our experience with the use of incobotulinumtoxinA (Xeomin) in the hand. We present 2 cases of patients with RP in bilateral hands who pres

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Negative / Null Result ReportOpen accessSurgery

Efficacy of Low Level Laser Therapy in Lumbar Discopathy Pain (Randomized Controlled Study)

A. Samarbakhsh, M. Shojaeei, M. Hami · 2014 · Global Spine Journal

Introduction Finding evidence based and effective method of managing low back pain (LBP) has been always a major dilemma in the field of neuromusculoskeletal system. The focus of this investigation is to establish a treatment regime for the discopathy origin of LBP using low level laser (LLL). This type of LBP is the cause of a significant number of days of sick leave in many countries. LLLT has not yet been fully adopted as a treatment method. Results of studies on LLL suggest that it reduces pain by a range of physiologic responses, such as increase in b-endorphins and depolarization blockag

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Negative / Null Result ReportOpen accessSurgery

Prospective ultrasonographic study of blood flow and testicular volume in patients submitted to surgical repair of inguinal hernia without using prosthesis

Cláudio de Saboya David, Alberto Goldenberg · 2018 · Acta Cirúrgica Brasileira

Abstract Purpose: To evaluate the behavior of arterial circulation and testicular volume in patients submitted to conventional inguinal hernia repair without the use of a synthetic prosthesis to reinforce the posterior wall. Methods: A prospective observational clinical trial was performed on 26 male patients with unilateral inguinal hernia types I and II by the Nyhus classification, who underwent surgical correction using the modified Bassini technique. Bilateral Doppler ultrasonography was performed preoperatively, at the third and at the sixth postoperative month. The studied variables were

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Negative / Null Result ReportOpen accessSurgery

Congestive ischemic colitis occurring after resection of left colon cancer: 4 case series

Takatsugu Fujii, Shigeo Toda, Yuki Nishihara et al. · 2020 · Surgical Case Reports

Abstract Background Ischemic colitis can occur after colectomy and is sometimes difficult to treat. We report 4 cases of refractory, delayed onset, regional congestive colitis occurring on the anal side of the anastomosis after laparoscopic left hemicolectomy. Case presentation A total of 191 patients underwent surgery for left colon cancer (transverse, descending, and sigmoid colon cancer) at our hospital from January 2012 to December 2017. During the procedures, the left colic artery (LCA) or sigmoid colic artery (SA) was dissected, the superior rectal artery (SRA) was preserved, and the inf

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Failed Experiment ReportOpen accessSurgery

Undesirable complication after transradial coronary angiography: A case report

Ozgur Altinbas, Mehmet Isik · 2024 · Turkish Journal of Vascular Surgery

Radial artery is one of the intervention cites for coronary angiography and has an increased tendency according to the successful results in the literature. However, some undesirable clinical situations may occur by using this route as with every invasive intervention. In this study, we presented a patient who had left upper limb ischemia following transradial angiography. An intimal flap with an approximate length of 15 cm was removed during embolectomy from the brachial artery. After multiple embolectomy procedures, axillo-brachial bypass was performed using the saphenous vein. However, isch

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Negative / Null Result ReportOpen accessSurgery

Effectiveness of Platelet-rich Plasma Injection as an Adjunct Treatment to Arthroscopy for TFCC Injury: A Retrospective Cohort Study

Abdulaziz Asiry, MBBS, DESC, FEBOPRAS, EBHS, Armaghan Dabbagh, PT, PhD, Hatan Mortada, MBBS et al. · 2024 · Plastic and Reconstructive Surgery, Global Open

Background:. Triangular fibrocartilage complex (TFCC) injuries can cause significant patient dysfunction. Platelet-rich plasma (PRP) has emerged as a potential adjunctive treatment for arthroscopic TFCC repair, with some studies suggesting improved outcomes. This study aims to evaluate and compare PRP as an adjunctive treatment in arthroscopic TFCC tear repair. Methods:. This retrospective cohort study examined patients undergoing arthroscopic TFCC repair at Institut de la Main, Paris, France (December 2021–2022). Patients were split into two groups: arthroscopic repair alone (1) and repair wi

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Negative / Null Result ReportOpen accessSurgery

Modulation of Remote Ischemic Preconditioning by Proinflammatory Cytokines in Renal Transplant Recipients

Homero Zapata-Chavira, Marco Hernández-Guedea, Julio César Jiménez-Pérez et al. · 2019 · Journal of Investigative Surgery

Aim: Remote ischemic preconditioning (RIPC) has been used as a strategy to reduce acute renal injury and ischemia-reperfusion injury (IRI) in renal transplantation (RT) with controversial results. Objective: To determine if RIPC modifies IRI in cadaveric RT recipients through inflammatory mediators and graft function. Methods: Twenty-nine RT recipients were studied, 12 in the control group (CG) and 17 in the RIPC group. RIPC which was performed on donors using a pneumatic tourniquet placed on both thighs for 10 min followed by the determination of IL-1, IL-6, TNF-α, VEGF, and ICAM-1, and hemat

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Negative / Null Result ReportOpen accessSurgery

The Relationship Between Serum Concentration of Interleukin-35 and FoxP3 Polymorphism in Patients Undergoing Coronary Artery Bypass Graft Surgery

Farzaneh Dasturian, Nadereh Naderi, Gholamreza Farshidfar et al. · 2020 · Brazilian Journal of Cardiovascular Surgery

Abstract Objective: To investigate the association between interleukin-35 (IL-35) levels and single nucleotide polymorphisms (rs3761548, rs3761547) of the FoxP3 gene in coronary artery bypass grafting (CABG) patients. Methods: We conducted a prospective study including 140 patients, who were scheduled for elective isolated on-pump CABG with cardiopulmonary bypass (CPB) from January 2017 to September 2018 in the Jorjani heart center. Blood samples were collected before and 12 hours after the operation. Serum levels of IL-35 were measured by enzyme-linked immunosorbent assay and the pattern of g

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