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Browse the failure-mode index

37 real negative results, null findings, and replication failures · Null Dataset. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Null DatasetOpen accessComputer Science

DCDB 2.0: a major update of the drug combination database

Yu Liu, Qichun Wei, Guocan Yu et al. · 2014 · Database

Experience in clinical practice and research in systems pharmacology suggested the limitations of the current one-drug-one-target paradigm in new drug discovery. Single-target drugs may not always produce desired physiological effects on the entire biological system, even if they have successfully regulated the activities of their designated targets. On the other hand, multicomponent therapy, in which two or more agents simultaneously interact with multiple targets, has attracted growing attention. Many drug combinations consisting of multiple agents have already entered clinical practice, esp

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Null DatasetOpen accessNeuroscience

Data visualization for inference in tomographic brain imaging

Cyril Pernet, Christopher R. Madan · 2019 · European Journal of Neuroscience

Tomographic imaging (i.e. magnetic resonance imaging [MRI], positron emission tomography [PET], X-ray computed tomography [CT]) offers a unique window in understanding structure-function relationships in the living brain. Nowadays, it is standard practice to acquire entire brain volumes and perform statistical analyses at each voxel, an approach known as statistical parametric mapping (Friston, Frith, Liddle, & Frackowiak, 1991). Because it is impossible to report the statistical results in every voxel, summary tables and figures are of importance. The choice made by authors to create such fig

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Null DatasetOpen accessEngineering

ATRNet-STAR: A Large Dataset and Benchmark Toward Remote Sensing Object Recognition in the Wild

Yongxiang Liu, Weijie Li, Li Liu et al. · 2026 · IEEE Transactions on Pattern Analysis and Machine Intelligence

The absence of publicly available, large-scale, high-quality datasets for Synthetic Aperture Radar Automatic Target Recognition (SAR ATR) has significantly hindered the application of rapidly advancing deep learning techniques, which hold huge potential to unlock new capabilities in this field. This is primarily because collecting large volumes of diverse target samples from SAR images is prohibitively expensive, largely due to privacy concerns, the characteristics of microwave radar imagery perception, and the need for specialized expertise in data annotation. Throughout the history of SAR AT

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Null DatasetOpen accessMedicine

Causes and Outcomes of Admission and Investigation of Tuberculosis in Adults with Advanced HIV in South African Hospitals: Data from the TB Fast Track Trial

Peter Beckwith, Mpho Tlali, Salome Charalambous et al. · 2021 · American Journal of Tropical Medicine and Hygiene

Tuberculosis (TB) remains the leading cause of hospitalization and in-hospital mortality in HIV-positive adults. Using data from hospital and clinic files, research databases, and autopsy, we describe causes and outcomes of admissions, and…

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Null DatasetOpen accessEngineering (General). Civil engineering (General)

Acquisition setup for rock fragmentation measurement in field conditions

Chairul Salam M., Maharani Rindu Widara, Ign Mahendradewa Adam et al. · 2026 · Journal of Engineering and Applied Science

Abstract Rock fragmentation is a key determinant of downstream excavation performance in surface mining operations. Among blasting design parameters, stemming depth governs explosive energy confinement; however, its field-scale influence on fragmentation quality and excavation efficiency remains insufficiently quantified. This study experimentally investigates the effect of two stemming depths (3 m and 4 m) on rock fragmentation characteristics and excavator cycle time through controlled field blasting trials conducted in a hard sandstone formation. All blasts were executed using identical dri

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Null DatasetMedicine

Integrating systemic toxicity and toxicokinetic data to inform the need for subchronic dog studies in human health safety assessments of agrochemicals.

Murphy L, Mingoia R, Bianchi E et al. · 2026 · Regulatory toxicology and pharmacology : RTP

Regulatory testing for agrochemicals has traditionally included a 90-day toxicity study in a non-rodent species, usually the dog. With growing emphasis on the 3Rs-replacement, reduction, and refinement of animal use-and increased adoption…

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Null DatasetOpen accessMedicine

Stabilization of Transport Properties in Thin Nonstoichiometric La<sub>1-x</sub>Sr<sub>x</sub>Mn<sub>y</sub>O<sub>3</sub> Films via Accelerated Aging for Magnetic Field Sensors.

Rudokas V, Koliada M, Stankevic V et al. · 2026 · Sensors (Basel, Switzerland)

Magnetic sensors based on the colossal magnetoresistance (CMR) effect in manganite thin films are promising for high-field measurements due to their wide operating range, low magnetoresistance anisotropy, and ability to function without…

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Null DatasetOpen accessComputer Science

Data Transmissions in Blockchain enabled AGVs

Junhan Liu, Shile Liu, Chenming Xu et al. · 2023 · arXiv

Automated Guided Vehicles (AGVs) operate in synergy to execute specific tasks. These vehicles exchange information to ensure seamless collaboration, prevent collisions, and eliminate task redundancy. The advent of blockchain technology offers a promising avenue for establishing a secure and dependable communication infrastructure for AGVs. Nonetheless, it becomes imperative for AGVs to adopt efficient data transmission methodologies, especially when interacting with the dynamic nature of blockchain infrastructure where data undergoes frequent modifications. In the present study, we introduce a

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Null DatasetOpen accessMedicine

The unsung hero: <i>ntnh</i> gene as complementary botulism marker.

Valdezate S, Valiente M, Díaz-Ramón S et al. · 2026 · Frontiers in cellular and infection microbiology

Botulism is a rare but severe neurological disease caused by botulinum neurotoxins (BoNTs). Standard diagnostic methods including the mouse bioassay (SMB) and bont gene type-specific PCR, are often limited by the high genetic diversity…

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Null DatasetOpen accessMedicine

Diagnostic performance of the Sepsis qPCR MX-30<sup>®</sup> panel compared with conventional blood culture in pediatric febrile neutropenia: a single-center retrospective study.

Kurtipek FB, Yozgat AK, Gökçek E et al. · 2026 · BMC infectious diseases

Background Febrile neutropenia (FN) is a frequent and potentially life-threatening complication in patients with hematologic malignancies. Prompt and accurate identification of bloodstream pathogens is essential to optimize antimicrobial…

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