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Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Failed Experiment ReportMedicine

Early onset radiation-induced leukoencephalopathy in patients treated for a glioblastoma by STUPP protocol and risk factors evaluation, an ancillary study of the phase III ASTER protocol.

Balcerac, Cuzzubbo, Bompaire et al. · 2026 · Revue neurologique

Since 2005, the standard treatment for newly diagnosed glioblastoma involves radiotherapy combined with concomitant and adjuvant temozolomide (TMZ), as per the Stupp protocol. A known long-term complication of radiotherapy is…

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Negative / Null Result ReportMedicine

Sleep and Haemophilia-A Case-Control Analysis of Associated Factors.

Schmidt, Brühl, Möllers et al. · 2026 · Haemophilia : the official journal of the World Federation of Hemophilia

Sufficient sleep is essential for maintaining both physical and mental health, yet data on sleep health among persons with haemophilia (PwH) remain limited. This study aimed to assess sleep in PwH compared to healthy controls (Con) and…

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Negative / Null Result ReportMedicine

Impact of the platelet storage time on transfusion-related adverse reactions: A French hemovigilance study.

Pires Marafon, Reuter, Isola et al. · 2026 · Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine

The legal shelf life of platelet concentrates (PCs) has been extended from 5 to 7 days in France since 2018. Our study aimed to determine whether this increase in PC storage time has produced a significant impact on…

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Negative / Null Result ReportMedicine

The Impact of Age on Military Trauma Outcomes: A Retrospective Analysis.

Akler, Gelman, Radomislensky et al. · 2026 · The Israel Medical Association journal : IMAJ

Age is a well-established prognostic factor in civilian trauma, where adverse outcomes increase with ages. Whether this pattern holds true in military trauma, where populations, injury mechanisms, and systems of care differ fundamentally,…

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Negative / Null Result ReportOpen accessMedicine

Well-being Index Scores and Subjective Health Status of Korean Healthcare Workers

Yoonhee Shin, Bohyun Park, Nam-eun Kim et al. · 2022 · Journal of Preventive Medicine and Public Health

Objectives The aim of this study was to evaluate the subjective level of health-related quality of life of Korean healthcare workers using various quality-of-life instruments. Methods This study included 992 participants, who were doctors and nurses. A survey was conducted between November 28 and December 4, 2019. Data from 954 participants divided into 3 groups (physicians, residents, and nurses) were analyzed. Four measurement tools (29 questions) were used in the survey to evaluate subjective health status and well-being. Results In the Mayo Well-being Index, burnout during work (88.5%) and

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Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system

Dry needling on latent and active myofascial trigger points versus oral diclofenac in patients with knee osteoarthritis: a randomized controlled trial

Yan-Tao Ma, Yu-Lin Dong, Bo Wang et al. · 2023 · BMC Musculoskeletal Disorders

Abstract Background Latent and active myofascial trigger points (MTrPs) in knee-associated muscles may play a key role in pain management among patients with knee osteoarthritis (KOA). The aim of this study was to investigate the effect of dry needling treatment on pain intensity, disability, and range of motion (ROM) in patients with KOA. Methods This randomized, single-blinded, clinical trial was carried out for 6 weeks of treatment and 6-month follow-up. A total of 98 patients met the entry criteria and were randomly assigned to the dry needling latent and active myofascial trigger point (M

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