The effect of subchronic cigarette smoke exposure on oxidative stress parameters and endothelial nitric oxide synthase in a rat aorta
Meity Ardiana; Budi Pikir; Anwar Santoso; Hanestya Hermawan; Makhyan Al-Farabi · 2021 · ARYA Atherosclerosis
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: The compounds in cigarette smoke are believed to cause oxidative stress, leading to endothelial dysfunction. Understanding the mechanism of endothelial dysfunction due to cigarette smoke is useful for the development of early and preventive therapy for cardiovascular diseases (CVDs) with smoking risk factors.METHODS: In this experimental study, a posttest-only control group design was used. 20 Wistar rats were divided into two groups: a smoking group (exposed to 40 cigarettes per day for 4 weeks) and a control group. After the exposure, the animals were sacrificed and aortas were r
Abstract by Meity Ardiana; Budi Pikir; Anwar Santoso; Hanestya Hermawan; Makhyan Al-Farabi, ARYA Atherosclerosis (2021) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.22122/arya.v17i0.2150