Negative / Null Result ReportOpen accessFood processing and manufacture
Ardiyanti Rahma Setiawati, Dedes Amertaningtyas, Ahmad Khoirul Umam · 2025 · Jurnal Ilmu dan Teknologi Hasil Ternak
Salted egg is a well-known traditional product, particularly in many Asian countries, where it is valued for its unique savory taste, extended shelf life, and convenience. Consumer demand for healthier, more appealing food has sparked interest in enriching salted eggs with natural ingredients. The purpose of this study was to analyze the effect of adding kaffir lime leaf powder (Citrus hystrix) and citronella leaf powder (Cymbopogon nardus) to salted eggs on pH, antioxidants, moisture and organoleptics. The research method used was experimental using a completely randomized design (CRD) with 6
View details →Negative / Null Result ReportOpen accessImmunologic diseases. Allergy
Kenji Morimoto, Junji Uchino, Takashi Yokoi et al. · 2021 · OncoImmunology
Although previous studies suggest that cancer cachexia is a poor prognostic factor for immune checkpoint inhibitor monotherapy, the impact of cancer cachexia on chemoimmunotherapy is unclear. We investigated the impact of cancer cachexia on the therapeutic outcomes of chemoimmunotherapy for non-small cell lung cancer (NSCLC). We retrospectively analyzed patients’ medical records with NSCLC who received chemoimmunotherapy in 12 institutions in Japan between January and November 2019. We defined cancer cachexia as weight loss exceeding 5% of the total body weight or a body mass index of < 20 kg/
View details →Negative / Null Result ReportOpen accessMedicine
Hassan Talakesh, Alizamen Salehifard Jouneghani, Karamali Kasiri et al. · 2024 · Journal of Shahrekord University of Medical Sciences
Background and aims: Constipation in children is a serious problem that affects both children and their families. We aimed to compare the clinical efficacy of lactulose and polyethylene glycol in the treatment of constipation in children. Methods: This randomized clinical trial was performed on 92 patients referred to a private gastroenterology clinic in Shahrekord, Iran. The patients were randomly assigned into two groups receiving polyethylene glycol or lactulose. Defecation patterns and complications were assessed 0, 3, 7, and 21 days after the intervention. Data were analyzed using the chi
View details →Negative / Null Result ReportOpen accessMedicine (General)
Krdžić Igor, Kenić Marko, Šćepanović Milena et al. · 2020 · Vojnosanitetski Pregled
Background/Aim. In colon and rectal cancer surgery, resection is considered radical when circumferential, proximal and distal resection margins are without the presence of tumor cells. Concept of total mesorectal excision in rectal surgery involves complete removal of the tumor with mesorectal fascia which surrounds lymph nodes, lymphatics and blood vessels. The aim of this study was to determine whether laparoscopic approach provides all parameters of oncological radicality as open surgery of colorectal cancer. Methods. The study included 122 patients with carcinoma of colon and rectum, divid
View details →Negative / Null Result ReportOpen accessMedicine
Fuengfa Khobkhun, Jenjira Thanakamchokchai · 2023 · Scientific Reports
Abstract Biological sexes (male and female) have been reported to influence postural control and balance due to differences in musculoskeletal structures, hormonal factors, and neuromuscular control. These factors can contribute to the turning performance, potentially leading to an increased incidence of falls, particularly during turning. Therefore, this study aimed to explore the whole-body coordination and stepping characteristics and during standing turns in healthy adults to determine the effects of biological sex and turn speed. Fifty participants (25 males and 25 females) completed 180°
View details →Negative / Null Result ReportOpen accessAnimal culture
Alberto Luiz Freire de Andrade Júnior, Patrícia Costa da Silva, Emerson Moreira de Aguiar et al. · 2012 · Revista Brasileira de Parasitologia Veterinária
Coccidiosis is a serious obstacle to sheep production, which is becoming a limiting factor, especially with regard to lamb production. However, there are few studies on this parasite in the State of Rio Grande do Norte. The aim of this study was to evaluate the action of decoquinate, added to mineral salt, for controlling Eimeria infection in lambs, and to identify which species are infecting sheep in the eastern region of the state. This study was carried out from August 2009 to January 2010, and used 76 animals. These were divided into two treatment groups: one with common mineral salt, and
View details →Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Akif Albayrak, Baris Ozkul, Mehmet Bulent Balioglu et al. · 2016 · Journal of Craniovertebral Junction and Spine
Study Design: Retrospective cohort study. Purpose: Facet joints are considered a common source of chronic low-back pain. To determine whether pathogens related to the facet joint arthritis have any effect on treatment failure. Materials and Methods: Facet joint injection was applied to 94 patients treated at our hospital between 2011 and 2012 (mean age 59.5 years; 80 women and 14 men). For the purpose of analysis, the patients were divided into two groups. Patients who only had facet hypertrophy were placed in group A (47 patients, 41 women and 6 men, mean age 55.3 years) and patients who had
View details →Negative / Null Result ReportOpen accessGynecology and obstetrics
Tom Marcelissen, Tanja Hüsch, Tiago Antunes-Lopes et al. · 2022 · Clinical and Experimental Obstetrics & Gynecology
Objectives: Minimally invasive sling procedures for the treatment of stress urinary incontinence has gained a topic of great interest for the last decades. However, postoperative storage symptoms after sling implantation or conventional surgical techniques are one of the most distressing complications which can significantly impair quality of life. The current review aims to focus on the development of storage symptoms after surgical treatment in comparison of different surgical techniques. Mechanism: A narrative review has been performed to identify literature reporting the incidence of stora
View details →Negative / Null Result ReportOpen accessMedicine (General)
Jae-Ik Lee, Dong-Hyun Kim, Hyun-Jin Yoo et al. · 2021 · Diagnostics
This study aimed to validate the accuracy and prediction performance of machine learning (ML), deep learning (DL), and logistic regression methods in the treatment of medial meniscus posterior root tears (MMPRT). From July 2003 to May 2018, 640 patients diagnosed with MMPRT were included. First, the affecting factors for the surgery were evaluated using statistical analysis. Second, AI technology was introduced using X-ray and MRI. Finally, the accuracy and prediction performance were compared between ML&DL and logistic regression methods. Affecting factors of the logistic regression method co
View details →Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Chaoyu Pang, Yongzheng Li, Ming Shi et al. · 2024 · Frontiers in Endocrinology
BackgroundCXC chemokine receptor 4 (CXCR4) is associated with the progression and metastasis of numerous malignant tumors. However, its relationship with Gastroenteropancreatic Neuroendocrine Neoplasms Grade 3 (GEP-NENs G3) is unclear. The aim of this study was to characterize the expression of CXCR4 in GEP-NENS and to explore the clinical and prognostic value of CXCR4.MethodsThis study retrospectively collected clinical and pathological data from patients with GEP-NENs who receiving surgery in Qilu Hospital of Shandong University from January 2013 to April 2021, and obtained the overall survi
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Vanessa Maria Nunes Roque, Nora Manoukian Forones · 2006 · Arquivos de Gastroenterologia
RACIONAL: O câncer colorretal é a quarta causa de câncer no Brasil e o 5-fluourouracil uma das principais drogas usadas no tratamento adjuvante e paliativo dessa doença. A toxicidade da quimioterapia e as alterações de qualidade de vida, causadas pela própria doença e pelo tratamento, são motivo de muitos estudos. OBJETIVO: Avaliar nos doentes com câncer colorretal em tratamento quimioterápico, a toxicidade e possíveis alterações da qualidade de vida. MÉTODOS: Durante o período de março de 2001 a maio de 2003 no Ambulatório de Oncologia da Disciplina de Gastroenterologia Clínica da Universidad
View details →Negative / Null Result ReportOpen accessNursing
Sedigheh Arta, Seyed Reza Mazlom, Shahram Amini et al. · 2017 · Journal of Evidence-Based Care
Background: Different approaches are available to irrigate the arterial catheter, such as continuous and intermittent techniques. However, there is a disagreement regarding the most appropriate method. Aim: this study aimed to compare the effect of two continuous and intermittent irrigation methods on complications of arterial catheter and partial thromboplastin time (PTT) in patients with coronary artery bypass (CABG) surgery. Method: This randomized clinical trial was conducted on 60 participants undergoing coronary artery bypass grafting surgery in open-heart surgery ICU at Imam Reza hospit
View details →Negative / Null Result ReportOpen accessAgriculture
Sofoluwe Nurudeen Afolabi · 2021 · Western Balkan Journal of Agricultural Economics and Rural Development
This study investigates the attribution effect of access to innovation on assets acquisition and development among rural women. The study analyzed gender differences in access to innovations and its consequence on assets ownership among rural males and females. Primary data for the study were sourced through a structured questionnaire. The data was fitted to a propensity score matching model in order to isolate the effect of access to innovation on gender differences in an asset acquisition. The findings showed that rural development drive requires innovative intervention in the rural areas an
View details →Negative / Null Result ReportOpen accessLanguage and Literature
Mavadat Saidi · 2020 · Journal of English Language Pedagogy and Practice
The learners’ ability to write a well-organized argumentative essay has gained prominence within the last decades. The multiple intelligences play a significant role in enhancing the precision of both language and thought during the writing process. The current study aimed at investigating the possible relationship between linguistic and logical intelligences and the frequency of informal fallacies and evidence types in Iranian EFL learners’ argumentative essays. To the end, a total of 110 upper-intermediate EFL learners were asked to respond to the relevant items of Multiple Intelligences Dev
View details →Failed Experiment ReportOpen accessPublic aspects of medicine
Jacqueline A. Benson MPH, Matthew Wilson MS, Aidan J. Flynn MS et al. · 2025 · Inquiry: The Journal of Health Care Organization, Provision, and Financing
The strongest risk factor for readmission to the hospital is impaired physical function. We sought to determine the usability and feasibility of a post-hospital behavioral intervention to improve mobility in older adults with significant morbidity and functional impairment. We conducted a two-arm pragmatic pilot randomized trial of a behavioral economics-informed intervention to increase daily steps in Veterans, age 60 or older, receiving home health (HH) services post-discharge. The intervention group received a multicomponent behavioral economics-informed intervention, including daily step c
View details →Negative / Null Result ReportOpen accessMedicine (General)
Michelle de Souza Rangel Machado, Tawana Vicente Bertagnolli, Eduardo Carvalho de Arruda Veiga et al. · 2020 · Clinics
OBJECTIVES: To assess the quality of life of hospitalized pregnant women with preeclampsia (PE), and compare with a group of healthy pregnant women (HP). METHODS: This was an observational cross-sectional study conducted among 58 pregnant women; 28 of them had preeclampsia and 30 were healthy. The WHOQOL-Bref questionnaire, which was divided into four aspects: physical, psychological, social, and environmental, was applied to each subject. RESULTS: A statistically significant difference was observed regarding maternal age (PE 27.8±6.2 x HG 23.0±6.6, p<0.01) and gestational age (PE 224±28.1 x H
View details →Negative / Null Result ReportOpen accessGeriatrics
Kendra Cooling, Danielle R. Bouchard, Molly Gallibois et al. · 2025 · JAR Life
Objective: To examine the effects of a standing intervention on gait speed for older adults living in long term care (LTC) residences. Design: A parallel superiority cluster randomized controlled trial. Setting and participants: LTC residences. A total of 95 LTC residents (n = 47 control; n = 48 intervention) participated in the study. Methods: LTC residences and therefore the residents from the homes were randomized to either the intervention group (standing up to 100 minutes/week) for 22 weeks or the control group (socializing with staff with no encouragement to stand for up to 100 minutes/w
View details →Negative / Null Result ReportOpen accessMedicine
Andres Montealegre, William Jimenez-Leal · 2019 · PLoS ONE
According to the social heuristics hypothesis, people intuitively cooperate or defect depending on which behavior is beneficial in their interactions. If cooperation is beneficial, people intuitively cooperate, but if defection is beneficial, they intuitively defect. However, deliberation promotes defection. Here, we tested two novel predictions regarding the role of trust in the social heuristics hypothesis. First, whether trust promotes intuitive cooperation. Second, whether preferring to think intuitively or deliberatively moderates the effect of trust on cooperation. In addition, we examin
View details →Negative / Null Result ReportOpen accessMedicine
Sung Hee Lim, Jong-Mu Sun, Joohyun Hong et al. · 2021 · The Korean Journal of Internal Medicine
Background/Aims Clinical trials have not consistently supported the use of induction chemotherapy (IC) for locally advanced head and neck squamous cell cancer. Hypopharynx and base of tongue (BOT) cancer has shown relatively poor survival. We investigated the role of IC in improving outcome over current chemoradiotherapy (CRT) in patients with hypopharynx and BOT cancer. Methods Treatment-naïve patients with stage III/IV (M0) hypopharynx or BOT cancer were randomly assigned to receive CRT alone (CRT arm: cisplatin 100 mg/m2 on D1 3-weekly, two times plus radiotherapy 68.4 Gy/30 fractions on we
View details →Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Runsheng Zhao, Kaiyu Fan, Weiqing Wan · 2023 · BMC Endocrine Disorders
Abstract Background To prevent thyroid storm and ensure surgical safety, it is imperative to regulate excessive thyroid hormone levels in patients with thyrotropin-secreting pituitary adenomas (TSHoma) prior to surgery. Somatostatin analogues (SSAs), such as octreotide, have showed efficacy in shrinking tumors, which may facilitate surgical resection. This retrospective study aimed to investigate the effect of shortterm preoperative octreotide treatment on the surgical outcome of TSHoma. Methods A total of 65 TSHoma patients from January 2010 to July 2019 were included in the study. Of these,4
View details →Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Andrea Buonsenso, Domenico Di Fonza, Gloria Di Claudio et al. · 2025 · Journal of Functional Morphology and Kinesiology
Objectives : The lat pulldown machine is one of the most versatile pieces of equipment for back strengthening, allowing variations in grip and load. However, there are significant gaps in the literature regarding the relationship between exercise modality and specific muscle activation. Methods : This study examined the electromyographic (EMG) activity of major back muscles during seven lat pulldown exercise variants that differed in grip type, width, and trunk inclination. Forty male subjects, with at least 5 years of resistance training experience, performed five repetitions of lat pulldown
View details →Negative / Null Result ReportOpen accessMedicine
Derya Sivri Aydın · 2019 · İstanbul Medical Journal
Introduction:To evaluate whether neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) have diagnostic value in endometrioma, which is a chronic inflammatory disease.Methods:A total of 187 patients who underwent surgery for adnexal mass, 97 patients diagnosed with endometrioma and 90 patients with benign cyst (corpus luteum, serous cysts or functional cysts), were included in this retrospective, comparative case series. NLR and PLR values obtained from preoperative complete blood count parameters were compared between the two groups.Results:There was no statistically significan
View details →Negative / Null Result ReportOpen accessPsychiatry
Sema Şimşek, Hasan Atak · 2021 · Psikiyatride Güncel Yaklaşımlar
In this study, the effect of 12-18 Age Family Education Program (AEP) on family functions was examined in a quasi-experimental study. The families in the experiment and control groups of the study were selected by purposeful sampling method. Self-Assessment Scale, The Family Assessment Device (FAD) and Me as a Parent Scale (MPS) were used as pretest-posttest data collection tools. A 14-session Family Education Program was carried out in the experimental group. No study was conducted with the control group. In the experimental group, it was observed that there was a significant difference betwe
View details →Negative / Null Result ReportOpen accessSpecial aspects of education
U.S.A Osuji · 2015 · West African Journal of Open and Flexible Learning
This study was carried out using a descriptive survey design to investigate the extent to which Open and Distance Learning (ODL) students in Nigeria manage their time effectively. One research question and two hypotheses were used in the study. Purposive sampling was used to select 312 ODL students from six centres across the geo-political zones of the country. The six centres were randomly selected from the zones. A 25-item Time Management Questionnaire (TMQ), in the form of a four-point Likert type scale adopted from the standardised Wayne University time management questionnaire, was used f
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Jianfeng Li, Hongjie Zhu, Nanzhi Luo et al. · 2024 · Discover Oncology
Abstract The optimal surgical approach for elderly patients with early-stage non-small cell lung cancer (NSCLC) remains a topic of debate. A retrospective analysis was conducted on patients who underwent pulmonary resection for early-stage NSCLC at our single institution between January 2018 and December 2022. Propensity score matching was used to balance baseline characteristics between the sublobar resection and lobectomy groups. Perioperative outcomes, pulmonary function recovery, postoperative quality of life, and survival were compared between the two groups. A total of 151 patients were
View details →Negative / Null Result ReportOpen accessForestry
Michael M. Müller, Leena Hamberg, Martti Varama · 2023 · Silva Fennica
Unequivocal evidence on the antagonistic effects of endophytic fungi associated with woody plants against insect herbivores has been documented in only a few cases so far. Experimental evidence of the significance of needle endophytes to coniferous trees has remained scant because it is difficult to obtain trees with needles free of endophytes that could be used as comparable controls for trees infected with endophytes. Previously we reported a new methodology to get Norway spruce (Picea abies (L.) Karst.) saplings without needle endophytes and to inoculate them with a needle endophyte Lophode
View details →Negative / Null Result ReportOpen accessMedicine
Laura Sterian Ward, Ilda Shizue Kunii, Rui Monteiro de Barros Maciel · 2000 · São Paulo Medical Journal
CONTEXT: Screening programs not only offer the opportunity to trace and treat almost all cases of congenital hypothyroidism but also mean large savings to the health system. However, carefully planned strategies are necessary to extend their benefits and reduce costs. OBJECTIVE: To determine the possible influence of maternal diseases that affect maternal-fetal placenta dynamics on primary thyroid stimulating hormone (TSH) screening for congenital hypothyroidism. DESIGN: Prospective non-randomized clinical trial with at least 3 months of follow-up. SETTING: A public university referral center
View details →Negative / Null Result ReportOpen accessMedicine
Magdalena Dudek, Marta Kałużna-Oleksy, Jacek Migaj et al. · 2018 · Journal of Medical Science
Background. Coronary artery disease (CAD) is one of the most important causes of death in both men and women. There are many gender differences among patients with CAD, including risk factors and acute coronary syndrome (ACS) outcomes. The latest reports showed that mortality due to CAD is higher in women than in men. Cardiac biomarkers play an important role in risk stratification and choice of treatment strategy in patients with ACS, however some of cardiac biomarkers show worse sensitivity and specificity in women. Aim. The aim was to investigate the sex-related differences in patients with
View details →Negative / Null Result ReportOpen accessSurgery
Christiane Simioni, Edward Araujo Júnior, Wellington P. Martins et al. · 2012 · Brazilian Journal of Cardiovascular Surgery
OBJETIVO: Comparar do débito cardíaco (DC) e a fração de ejeção (FE) do coração de fetos masculinos e femininos obtidos por meio da ultrassonografia tridimensional, utilizando o spatio-temporal image correlation (STIC). MÉTODOS: Realizou-se um estudo de corte transversal com 216 fetos normais, entre 20 a 34 semanas de gestação, sendo 108 masculinos e 108 femininos. Os volumes ventriculares no final da sístole e diástole foram obtidos por meio do STIC, sendo as avaliações volumétricas realizadas pelo virtual organ computer-aided analysis (VOCAL) com rotação de 30º. Para o cálculo do DC utilizou
View details →Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Sahil Kumar, Elise Bertin, Cormac O'Dwyer et al. · 2023 · Asian Journal of Andrology
Transmasculine individuals, considering whether to undergo total hysterectomy with bilateral salpingectomy, have the option to have a concomitant oophorectomy. While studies have evaluated hormone changes following testosterone therapy initiation, most of those patients have not undergone oophorectomy. Data are currently limited to support health outcomes regarding the decision to retain or remove the ovaries. We performed a retrospective chart review of transmasculine patients maintained on high-dose testosterone therapy at a single endocrine clinic in Vancouver, British Columbia, Canada. Twe
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