Impact of cancer cachexia on the therapeutic outcome of combined chemoimmunotherapy in patients with non-small cell lung cancer: a retrospective study
Kenji Morimoto; Junji Uchino; Takashi Yokoi; Takashi Kijima; Yasuhiro Goto; Akira Nakao; Makoto Hibino; Takayuki Takeda · 2021 · OncoImmunology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Although previous studies suggest that cancer cachexia is a poor prognostic factor for immune checkpoint inhibitor monotherapy, the impact of cancer cachexia on chemoimmunotherapy is unclear. We investigated the impact of cancer cachexia on the therapeutic outcomes of chemoimmunotherapy for non-small cell lung cancer (NSCLC). We retrospectively analyzed patients’ medical records with NSCLC who received chemoimmunotherapy in 12 institutions in Japan between January and November 2019. We defined cancer cachexia as weight loss exceeding 5% of the total body weight or a body mass index of < 20 kg/
Abstract by Kenji Morimoto; Junji Uchino; Takashi Yokoi; Takashi Kijima; Yasuhiro Goto; Akira Nakao; Makoto Hibino; Takayuki Takeda, OncoImmunology (2021) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1080/2162402x.2021.1950411