e-ISSN: Pending
Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology

Expression and clinical value of CXCR4 in high grade gastroenteropancreatic neuroendocrine neoplasms

Chaoyu Pang; Yongzheng Li; Ming Shi; Zhiyao Fan; Xin Gao; Yufan Meng; Shujie Liu; Changhao Gao · 2024 · Frontiers in Endocrinology

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Abstract

BackgroundCXC chemokine receptor 4 (CXCR4) is associated with the progression and metastasis of numerous malignant tumors. However, its relationship with Gastroenteropancreatic Neuroendocrine Neoplasms Grade 3 (GEP-NENs G3) is unclear. The aim of this study was to characterize the expression of CXCR4 in GEP-NENS and to explore the clinical and prognostic value of CXCR4.MethodsThis study retrospectively collected clinical and pathological data from patients with GEP-NENs who receiving surgery in Qilu Hospital of Shandong University from January 2013 to April 2021, and obtained the overall survi

Abstract by Chaoyu Pang; Yongzheng Li; Ming Shi; Zhiyao Fan; Xin Gao; Yufan Meng; Shujie Liu; Changhao Gao, Frontiers in Endocrinology (2024) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.3389/fendo.2024.1281622