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Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology

The effect of preoperative short-term octreotide treatment to surgery in thyrotropin-secreting pituitary adenomas: a retrospective cohort study

Runsheng Zhao; Kaiyu Fan; Weiqing Wan · 2023 · BMC Endocrine Disorders

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Abstract Background To prevent thyroid storm and ensure surgical safety, it is imperative to regulate excessive thyroid hormone levels in patients with thyrotropin-secreting pituitary adenomas (TSHoma) prior to surgery. Somatostatin analogues (SSAs), such as octreotide, have showed efficacy in shrinking tumors, which may facilitate surgical resection. This retrospective study aimed to investigate the effect of shortterm preoperative octreotide treatment on the surgical outcome of TSHoma. Methods A total of 65 TSHoma patients from January 2010 to July 2019 were included in the study. Of these,4

Abstract by Runsheng Zhao; Kaiyu Fan; Weiqing Wan, BMC Endocrine Disorders (2023) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1186/s12902-023-01398-z