e-ISSN: Pending
WASTE Journal

Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Effect of Thermal Processing on the Nutritional Composition and Bioactive Compounds of 'Largueta' Almonds (<i>Prunus dulcis</i>).

Fernández-León MF, Flórez Acosta LR, Fernández-León AM · 2026 · Foods (Basel, Switzerland)

Almond ( Prunus dulcis ) is a highly nutritious nut, rich in unsaturated fatty acids, fibre, and bioactive compounds such as tocopherols, phenolic compounds, and carotenoids. Processing methods commonly applied in the almond industry,…

View details →
Negative / Null Result ReportMedicine

Evaluation of the first edition of the 'Spirituality in medicine' programme implemented for medical students at the Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz, Poland. Pre- and post-test research.

Fopka-Kowalczyk M, Krajnik M · 2026 · BMC medical education

Background This article presents an evaluation of the first obligatory programme on 'Spirituality in Medicine' for medical students in Poland, implemented at the Collegium Medicum in Bydgoszcz of the Nicolaus Copernicus University in…

View details →
Failed Experiment ReportMedicine

Effects of a 15-week recreational football programme on insulin resistance and glycaemic control in inactive premenopausal women with mild arterial hypertension: A randomised controlled trial.

Póvoas S, Castagna C, Connolly LJ et al. · 2026 · Journal of sports sciences

This study aimed to investigate the impact of a 15-week recreational football intervention on insulin resistance and glycaemic control in inactive premenopausal women with mild hypertension. A total of 41 women, aged 35-50 years, were…

View details →
Failed Experiment ReportOpen accessMedicine

A comparison of student evaluations of teaching and learning in the inverted classroom model versus traditional lectures in dental education.

Reuter AK, Deschner J, Schütz L et al. · 2026 · BMC medical education

Introduction The inverted classroom model (ICM) is a learner-centred approach that aims to promote engagement, independence and deeper understanding by shifting knowledge acquisition to self-directed learning before class and using class…

View details →
Failed Experiment ReportMedicine

Reflectance confocal microscopy for monitoring treatment response in superficial basal cell carcinoma: diagnostic challenges due to scar formation.

Clark M, Wuennenberg J, Maghfour J et al. · 2026 · Clinical and experimental dermatology

Background Reflectance confocal microscopy (RCM) criteria for the in vivo diagnosis of superficial basal cell carcinoma (sBCC) lesions have been validated, with studies indicating a high level of diagnostic sensitivity. However, there…

View details →
Negative / Null Result ReportMedicine

Angiotensin (1-7) exaggerates albuminuria and nephrin gene expression but does not modulate renal function-specific microRNAs expressions in kidneys of db/db mice.

Malatiali S, Khamisi S, Kilarkaje N · 2026 · Acta diabetologica

Aim This study investigated the effects of angiotensin (1-7) on diabetes-induced renal injury and renal miRNA levels in obese type 2 diabetic db/db mice. Methods Treatment with angiotensin (1-7) (500 μg/kg; i.p.) was started when the mice…

View details →
Negative / Null Result ReportMedicine

Effect of different positions of lumbar traction on pain, function, and range of motion in adults with non-specific low back pain: a randomized clinical trial.

Mahmoud WS, Alhowimel A, Almotery A et al. · 2026 · Scientific reports

Non-specific low back pain (NSLBP) represents about 80-95% of all LBP cases, yet the optimal lumbar traction position for effective treatment remains debated. To investigate the effect of different positions during lumbar traction on pain,…

View details →
Negative / Null Result ReportMedicine

Thermographic response to acute muscle fatigue and delayed onset soreness (DOMS) following a protocol until exhaustion with concentric exercises in the triceps suralis.

Cabizosu A, Zoffoli A, Mevi R et al. · 2026 · Physiological measurement

Objective. Infrared thermography is projected as an innovative and very promising tool for the observation of muscle response to fatigue. The aim of this study was to observe the skin temperature (Tsk) by thermography about acute muscle…

View details →
Negative / Null Result ReportMedicine

Changes in sulphur content, uptake, internal efficiency index, harvest index and N:S ratio in pea plants from the four-leaf stage to full maturity.

Wysokinski A, Wiśniewska-Kadżajan B, Łozak I · 2026 · BMC plant biology

Background Sulphur is an important macronutrient for legume plants because it influences the formation and functioning of root nodules, the activity of enzymes reducing molecular nitrogen to available forms for plants, the formation of…

View details →
Negative / Null Result ReportMedicine

Clinical course of Graves' orbitopathy in children with newly diagnosed hyperthyroidism: a prospective observational study.

Tepe D, Deligozoglu D, Baskan C et al. · 2026 · Journal of pediatric endocrinology & metabolism : JPEM

Objectives Although Graves' orbitopathy (GO) in childhood is generally considered milder than in adults, data regarding its clinical course and relationship with thyroid autoimmunity remain limited. This study aimed to evaluate the…

View details →
Negative / Null Result ReportMedicine

Thrombotic Outcomes Associated With Factor Eight Inhibitor Bypassing Activity Use in Neonatal and Infant Cardiac Surgery Including the Norwood Procedure: A Propensity Score‒Matched Analysis.

Houska N, McCaw N, Meneses EC et al. · 2026 · Journal of cardiothoracic and vascular anesthesia

Objectives To describe thrombotic outcomes associated with Factor Eight Inhibitor Bypassing Activity (FEIBA) exposure in neonates and infants undergoing cardiac surgery with cardiopulmonary bypass (CPB), including the Norwood procedure.…

View details →
Negative / Null Result ReportMedicine

Comparison of pain perception and heart rate between Dentapen and Vibraject during local anesthesia administration in adult patients: a randomized clinical study.

Almuashi H, AbuMostafa A · 2026 · Quintessence international (Berlin, Germany : 1985)

Objective The management of pain in dental procedures is crucial, as local anesthetic injections may induce patient anxiety and discomfort. Various techniques including Vibraject and Dentapen have been devised to alleviate injection…

View details →
Negative / Null Result ReportMedicine

Trends and regional inequalities in cerebrovascular disease mortality in Peru: An ecological time-series analysis, 2017-2025.

Veli-Quispe D, Urquizo-Prado S, Cesare-Ariza E et al. · 2026 · Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association

Background Cerebrovascular disease remains a leading cause of mortality worldwide. In Peru, evidence on recent mortality trends and regional disparities is limited. Objective To evaluate temporal trends and regional disparities in…

View details →
Negative / Null Result ReportMedicine

Impact of Aflibercept Dosing Frequency on Retinal Nonperfusion Progression Assessed by Ultra-Widefield Angiography After Endolaserless Vitrectomy for Proliferative Diabetic Retinopathy-Related Vitreous Hemorrhage.

Qin LG, Camarda ND, Kasetty VM et al. · 2026 · Journal of vitreoretinal diseases

Purpose: To investigate the effect of intravitreal (IVT) aflibercept injection monotherapy on retinal ischemia in eyes with severe proliferative diabetic retinopathy (PDR) that underwent pars plana vitrectomy (PPV) without panretinal…

View details →
Failed Experiment ReportMedicine

Effect of irisin on miRNA-associated changes in the PGC-1α/FNDC5/BDNF Axis in an in vitro model of MPP⁺-induced Parkinson's disease.

Karabaş T, Sancar H, Şumnulu D et al. · 2026 · Molecular biology reports

BACKGROUND: In this study, the neuroprotective potential of irisin was evaluated in an MPP⁺-induced SH-SY5Y in vitro Parkinson’s disease model through miRNA-associated changes related to the PGC-1α/FNDC5/BDNF axis. MATERIAL AND METHOD: An…

View details →