Negative / Null Result ReportOpen accessMedicine (General)
ZHAO Guangqiang, NAN Dongqi, YUAN Siqi · 2024 · 陆军军医大学学报
Objective To explore the action mechanism of tauroursodeoxycholic acid (TUDCA) promoting intracellular clearance of Burkholderia pseudomallei (B. pseudomallei) in RAW264.7 macrophages. Methods After TUDCA of different concentrations were used to treat RAW264.7 cells pre-infected with B. pseudomallei for 8 h or not, flow cytometry was applied to detect the apoptosis of the infected and control cells. In addition, another endoplasmic reticulum stress (ERS) inhibitor 4-PBA was used to detect the apoptosis and proliferation of host cells after B. pseudomallei infection with Annexin-V/PI double sta
View details →Negative / Null Result ReportOpen accessFinance
Winda Noor Nawang Wulan, Suharyati , Rosali · 2019 · Ekonomi dan Bisnis
The development of information and communication technology in the era of globalization is growing rapidly. This has a significant impact on internet usage in Indonesia. So that makes Indonesia a very potential market for e-commerce, which has triggered the emergence of various online stores in Indonesia. Achieving success in ecommerce business in online stores in Indonesia requires a strategy. Shopee is an ecommerce company that runs the C2C mobile marketplace business, which allows users to buy or sell goods through applications available on the iOS and Android platforms. This research is a
View details →Negative / Null Result ReportOpen accessMedicine
Tomoharu Takeuchi, Risa Nakamura, Megumi Hamasaki et al. · 2023 · BMC Research Notes
Abstract Objective Galectins are sugar-binding proteins that participate in many biological processes, such as immunity, by regulating host immune cells and their direct interaction with pathogens. They are involved in mediating infection by Schistosoma mansoni, a parasitic trematode that causes schistosomiasis. However, their direct effects on schistosomes have not been investigated. Results We found that galectin-2 recognizes S. mansoni glycoconjugates and investigated whether galectin-1, 2, and 3 can directly affect S. mansoni in vitro. Adult S. mansoni were treated with recombinant galecti
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Yulu Miao, Bin Wang, Jing Hu et al. · 2022 · Frontiers in Pharmacology
Lung infection is a common complication induced by stroke and seriously affects the prognosis and life quality of patients. However, effective therapeutic strategies are still lacking. In the present study, the herb formula GCis was confirmed to prevent pulmonary infection induced by intracerebral hemorrhage (ICH). The animal model of lung infection induced by ICH, GCis (Ginseng Radix et Rhizoma, Aconiti Lateralis Radix Praeparata, and Cistanches Herba) was orally administrated every day for 7 days. Lung microbial biomass and pathological results showed that the GCis formula pretreatment signi
View details →Negative / Null Result ReportOpen accessPublic aspects of medicine
Tatin Wahyanto, Stefanus Supriyanto, Nyoman Anita Damayanti et al. · 2020 · Journal of Public Health Research
Background: The high turnover rate in the healthcare industry needs serious attention since it influences hospital service quality. So, there is a need to develop a new framework known as people equity, that can be used to manage intangible assets and reduce employees’ intention to leave. The purpose of this study therefore was to develop a model of people equity as a strategy for enhancing employees’ intention to stay. Design and methods: An analytical cross-sectional design was used to measure the associations between variables. 154 respondents were selected from stratified random sampling t
View details →Negative / Null Result ReportOpen accessMedicine
Hassan Nakisa, Fatemeh Ayoobi, Vahid Ehsani et al. · 2015 · مجله دانشگاه علوم پزشکی بیرجند
Background and Aim: Oxidative stresses are involved in neuronal degeneration of substantia nigra and thereby induction of Parkinson's disease. It is reported that Foeniculum Vulgare L. can affect lactating and modulating dopaminergic system activity and antioxidant activity as well. In the present study, the effects of methanolic extract of Foeniculum Vulgare seeds on a Parkinson’s disease model induced by ICV injection of 6-hydroxydopamin (6-OHDA) in female rats were investigated. Materials and Methods: In this experimental study, 60 female rats were randomly divided into 6 equal groups inclu
View details →Negative / Null Result ReportOpen accessEducation
Candra Mustika, Rahma Nurjanah, Sylvia Kartika Wulan · 2023 · JPPI (Jurnal Penelitian Pendidikan Indonesia)
Poverty and inequality are the main problems faced by a country including Indonesia. The purpose of this study was to determine and analyze the comparison of poverty and inequality levels on the islands of Sumatra and Java and to analyze the effect of the human development index (HDI), gross regional domestic product (GRDP), the level of open unemployment (TPT) and total population on poverty and income distribution inequality in Sumatra and Java. The research method used is quantitative descriptive with multiple regression analysis using panel data with provincial research objects on the isla
View details →Negative / Null Result ReportOpen accessAnimal culture
Stefanie Alvarenga Santos, José Maurício de Souza Campos, Sebastião de Campos Valadares Filho et al. · 2010 · Revista Brasileira de Zootecnia
Foram avaliadas dietas com silagem de milho e concentrado à base de farelo de soja ou farelo de algodão para fêmeas leiteiras. Quatro dietas experimentais foram constituídas da combinação de dois níveis de concentrado (1 ou 2 kg) e duas fontes proteicas (farelo de soja ou farelo de algodão). Observou-se efeito da interação nível de concentrado fonte proteica no consumo de matéria seca (MS), fibra em detergente neutro (FDN) e no consumo de nutrientes digestíveis totais (NDT). A quantidade de concentrado influenciou os consumos de proteína bruta (PB), FDN, extrato etéreo (EE), carboidratos nãofi
View details →Negative / Null Result ReportOpen accessComputer applications to medicine. Medical informatics
Qiwei Li, Jie Zhou · 2025 · Journal of Medical Internet Research
BackgroundNews portrayals of physicians, especially in China, often depict them as vulnerable—overworked, with inadequate compensation, or as victims of violence. These portrayals may send mixed signals to the public, yet their impact remains underexplored. Understanding their impact is essential for informing media strategies and improving physician-patient relationships. ObjectiveThis study investigated how portrayals of physicians as vulnerable influence public evaluations of their competence, warmth, morality, and overall trust and considered the moderating effects of involvement (ie, hosp
View details →Negative / Null Result ReportOpen accessPlant culture
Niloofar Montazemi, Akram Halajnia, reza khorassani et al. · 2023 · بوم شناسی کشاورزی
Introduction Organic fertilizer tea is a treated solution of organic fertilizers that contains a variety of organic compounds, nutrients and a wide range of microorganisms and their metabolites. In recent years production and use of organic tea as a liquid biological fertilizer or biological pesticides is expanding towards sustainable agriculture. There are many benefits to using tea compost, including providing the nutrients for plant which can reduce the use of chemical fertilizers. A variety of organic compounds can be used to make tea. In the preparation of aerobic organic tea, except for
View details →Negative / Null Result ReportOpen accessMedicine
Mohsen Dalband, Mona Isapour, Pantea Nazeman · 2016 · Regeneration, Reconstruction & Restoration
Introduction: Antibiotics are routinely administered in clinical setting for prevention of infections in surgeries and as a routine supplement to the culture medium. The nobility of the present study was to evaluate the effect of two commonly used antibiotics, clindamycin and cefazolin, in dental treatments, on osteogenic capability of periodontal ligament stem cells (PDLSCs). Materials and Methods: PDLSCs were isolated from periodontal ligament (PDL) of the root section out of four healthy extracted teeth. The cells were incubated in the following medium for 28 days: (1) Osteogenic medium (OM
View details →Negative / Null Result ReportOpen accessBusiness
RITA SUIRLAN, SUIRLAN · 2024 · Sriwijaya International Journal of Dynamic Economics and Business
This research examines the efforts that must be made by the government in realizing strong food security through indicators of the sustainable food sector on the island of Sumatra for 2018-2022. Food sector indicators include poor population , food inflation, per capita rice consumption, insufficient food consumption, and food insecurity. While indicators to strengthen food security by looking at the food security index. The research findings that the variable food inflation (IBM) has a positive and significant effect on the food security index (IKP), while the variables of the poor (PM), rice
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Jiawei Chen, Hongsheng Deng, Jiaxi He et al. · 2022 · Frontiers in Oncology
IntroductionThe interval between neoadjuvant immunochemotherapy and surgery in patients with non-small cell lung cancer (NSCLC) has not been well characterized. This study investigated the association between the time-to-surgery (TTS) interval and surgical–pathological outcomes.MethodClinical data of patients who received neoadjuvant immun-ochemotherapy followed by surgery for NSCLC between January 2019 and September 2021 were collected. The patients were divided into three groups based on TTS interval: the early-surgery group (ESG), the standard-surgery group (SSG), and the delayed-surgery gr
View details →Negative / Null Result ReportOpen accessMedicine
Amin Ebneshahidi, Mojtaba Akbari, Masood Mohseni · 2013 · Advanced Biomedical Research
Introduction: Haloperidol has an established role in nausea and vomiting prophylaxis and possible effects on multiple aspects of postoperative recovery including pain and sedation. The purpose of this study was to evaluate the effects of low-dose intraoperative intravenous haloperidol on quality of recovery (QoR) and pain control after general anesthesia and surgery. Methods: Ninety eight American Society of Anesthesiologists (ASA) physical status I-II patients undergoing elective general, gynecologic or orthopedic surgery under general anesthesia were enrolled. Participants were randomly allo
View details →Negative / Null Result ReportOpen accessAgriculture
Dija BHANDARI, Stella ARLOVIĆ, Marija GALIĆ et al. · 2024 · Journal of Central European Agriculture
The cultivation of energy crops and the use of biomass ash are part of a sustainable energy economy and have a major impact on the environment. Biomass ash can be used as a soil conditioner due to its chemical composition with essential micro- and macronutrients and has a proven positive effect on the physicochemical properties of soils. With the increasing interest and use of bioenergy species, the production of biomass ash is also increasing and is expected to increase further in the future. Therefore, the correct use of this product is important. Ensuring its use to enrich soils will streng
View details →Negative / Null Result ReportOpen accessDiseases of the endocrine glands. Clinical endocrinology
Camila Viecceli, Camila Viecceli, Ana Carolina Viana Mattos et al. · 2022 · Frontiers in Endocrinology
ObjectiveThe first-line treatment for Cushing’s disease is transsphenoidal surgery, after which the rates of remission are 60 to 80%, with long-term recurrence of 20 to 30%, even in those with real initial remission. Drug therapies are indicated for patients without initial remission or with surgical contraindications or recurrence, and ketoconazole is one of the main available therapies. The objective of this study was to evaluate the safety profile of and the treatment response to ketoconazole in Cushing’s disease patients followed up at the endocrinology outpatient clinic of a Brazilian uni
View details →Negative / Null Result ReportOpen accessBusiness
Irnin Miladdyan Airyq, Aida Vitayala Sjafri Hubeis, Anggraini Sukmawati · 2023 · Jurnal Aplikasi Bisnis dan Manajemen
The era of globalization presents several challenges related to human resource management. Every organization is appropriate to have qualified and highly competitive human resources to compete during dynamic changes. Employees as individuals and groups in an organization certainly have unique differences in personality. Employee performance can acquire optimal if they are experts in their fields and are established with a valuable organizational culture. Therefore, its purpose is to analyze the influence of competence, leadership, and organization culture on human resource performance and iden
View details →Negative / Null Result ReportOpen accessAccounting. Bookkeeping
Khan, Sania · 2021 · Accounting
This study aims to investigate the impact of human resource accounting (HRA) on the overall performance of the organization. By presenting the details of HRA the study identifies various dimensions of organizations’ financial aspects viz., human capital efficiency, organization profitability, return on asset, and return on equity. To understand the impact of various measurements, the study collected required data from 268 responses of human resource and finance departments of SME firms and analyzed the data using linear regression and the result of ANOVA and coefficient values illustrated ther
View details →Negative / Null Result ReportOpen accessSocial Sciences
Muhammad Dedy Palguno, Devi Valeriani, Suhartono Suhartono · 2020 · Sorot
Pertumbuhan Ekonomi adalah salah satu indikator penting untuk melihat keberhasilan pembangunan ekonomi pada suatu negara atau daerah. Suatu perekonomian dikatakan mengalami pertumbuhan ekonomi jika jumlah produksi barang dan jasanya meningkat dan produk domestik regional bruto merupakan salah satu indikator penting untuk mengetahui kondisi ekonomi di suatu daerah dalam suatu periode tertentu baik atas dasar harga berlaku maupun atas dasar harga konstan. Tujuan Penelitian adalah untuk melihat pengaruh pendapatan asli daerah (PAD) dan belanja modal terhadap pertumbuhan ekonomi. Data yang digunak
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Chun Xie, Tao Huang, Yingying Wang et al. · 2025 · Brain Sciences
Backgrounds and Objectives : Obesity presents a significant global public health challenge and is associated with declines in both general and food-related inhibitory control, crucial for maintaining a healthy weight and preventing obesity progression. An increasing body of research suggests that acute aerobic exercise may improve inhibitory function. However, the effects and underlying mechanisms of acute aerobic exercise on both general and food-related inhibition in obese adults remain unclear. This study aimed to explore the potential impacts and underlying neuroelectronic mechanisms of a
View details →Negative / Null Result ReportOpen accessSpecial aspects of education
Markus H. Hefter, Veit Kubik, Kirsten Berthold · 2023 · International Journal of Educational Technology in Higher Education
Abstract In recent years, COVID-19 policy measures massively affected university teaching. Seeking an effective and viable way to transform their lecture material into asynchronous online settings, many lecturers relied on prerecorded video lectures. Whereas researchers in fact recommend implementing prompts to ensure students process those video lectures sufficiently, open questions about the types of prompts and role of students’ engagement remain. We thus conducted an online field experiment with teacher students at a German university (N = 124; 73 female, 49 male). According to the randoml
View details →Negative / Null Result ReportOpen accessMicrobiology
Hamideh Raeisi, Masoumeh Azimirad, Elham Abdemohamadi et al. · 2023 · Frontiers in Microbiology
IntroductionThe dramatic increase in multidrug-resistance of Clostridioides difficile isolates has led to the search for new complementary medicines against C. difficile infection (CDI). In this study, we aimed to examine the inhibitory effects of hydroethanolic extract of Mentha longifolia L. (ETOH-ML) on the growth of C. difficile RT001 and its toxigenic cell-free supernatant (Tox-S)-induced inflammation and apoptosis.MethodsThe active phytochemical components of ETOH-ML were detected using GC and HPLC. The antimicrobial properties of the extract were examined against C. difficile RT001. Fur
View details →Negative / Null Result ReportOpen accessAgriculture
Piotr Pokrzywa, Ewa Cieślik, Magdalena Surma · 2019 · Annals of Agricultural and Environmental Medicine
Introduction and objective Mycotoxins are toxic metabolites produced by certain types of fungi, causing pathological changes in humans and animals. The aim of this study was to assess the degree of contamination of selected cereal grains, bran and cereal products intended for children, with mycotoxins using GCxGC-TOF-MS technique. The study involved mycotoxins belonging to the type A and B trichothecenes group, including T-2 toxin (T-2), HT-2 toxin (HT-2), scirpenol (SCI), 15-monoacetoxyscirpenol (15-MAS), diacetoxyscirpenol (DAS), triacetoxyscirpenol (TAS), fusarenon-X (FUS-X), nivalenol (NIV
View details →Negative / Null Result ReportOpen accessIndustrial safety. Industrial accident prevention
Kan Shimazaki, Yo Ishigaki, Kazunori Hayashi et al. · 2025 · Environmental and Occupational Health Practice
Objectives: To evaluate the effects of carbon dioxide (CO2) concentrations in automobiles on driving performance. Methods: A driving simulator experiment was conducted with eight taxi drivers. The experiment was conducted under low CO2 concentration (<500 ppm) and high CO2 concentration (5,000 ppm) conditions. To evaluate driving performance and cognitive function, three measures were employed: a two-back task, an LED response task, and a driving assessment. The driving assessment used scoring criteria from the driving license proficiency test. Results: Poisson regression analysis showed that
View details →Negative / Null Result ReportOpen accessDentistry
Zahra Bahrololoomi, Farnaz Farahat, Shirin Pajouhande et al. · 2025 · Journal of Dental Materials and Techniques
Objective: Coronal restoration of pulpotomized primary molars plays a vital role in ensuring the long-term success of the treatment. This study aimed to evaluate the effect of fiber reinforcement on the fracture resistance of pulpotomized primary molars restored with flowable or paste bulk-fill composite resins in comparison to a conventional composite resin.Methods: In this in vitro experimental study, 48 primary molars were randomly allocated into six groups (n=8). The teeth were pulpotomozed and restored with the following materials: Group 1: Conventional composite resin, Group 2: Fiber+ co
View details →Negative / Null Result ReportOpen accessPlant culture
Haoran Wang, Ping Li, Ying Han et al. · 2026 · Horticulturae
To clarify the regulatory mechanism of NLA on tomato plant architecture and fruit quality, wild-type (WT), nla mutant (narrow leaf angle), and NLA overexpression lines (OE1, OE2) were used as materials, and the study was carried out through genetic analysis, phenotypic and quality determination, and gene expression analysis. The results showed that the tomato leaf angle is controlled by a single gene with semi-dominant inheritance. The nla mutant forms a compact plant architecture due to reduced cell volume at the leaf angle. During vegetative growth, it exhibited significantly increased plant
View details →Negative / Null Result ReportOpen accessEducation (General)
Ishfaq Ahmad Malik, Seid Ahmyaw Adem, Adil Rasool · 2025 · Cogent Education
Based on the Theory of Planned Behaviour (TPB), this study examines the interplay between perceptions of educational artificial intelligence (EdAI) tools—specifically their perceived benefits, hedonic motivation, weaknesses, and risks—interact with TPB constructs (attitude, subjective norms, and perceived behavioural control) in shaping adoption intentions. Using a quantitative design, data were collected through an online survey of 344 students from higher education institutions (HEIs) in Sub-Saharan Africa (SSA). Partial Least Squares Structural Equation Modelling (PLS-SEM) was employed to t
View details →Negative / Null Result ReportOpen accessChemistry
Naveed Ahmed, Andrea Straub · 2025 · ChemEngineering
This study aims to estimate the organic load of oily wastewater by using Chemical Oxygen Demand (COD) measurements, addressing the analytical challenges posed by the hydrophobic, nonpolar, and often emulsified nature of Fats, oil and grease (FOG). This study established a reproducible and practical methodology for measuring COD in wastewater containing FOG at a laboratory scale, utilizing the nonionic surfactant T80 as a solubilizing and emulsifying agent. Precise gravimetric methods were employed to measure the mass of T80 (indirectly from volume (100–1400 µL/L)) added, and its correlation wi
View details →Negative / Null Result ReportOpen accessAgriculture (General)
Yuan Qiu, Yamin Wang, Yaqiong Fan et al. · 2023 · Agriculture
Growing crops in salt-affected soils has become increasingly important for sustainable development in arid and semi-arid regions. Knowledge on the responses of alfalfa root development, yield, and quality to soil salinity is critical for assessing the productivity and profitability of salt-affected soils. A field experiment with a total of six treatments combining three soil salinity levels and two biosolids fertilizer levels was conducted in 2018 and 2019 in northwest China. For salinity treatments, the salt addition rates were 2‰, 4‰, and 6‰ of 0–60 cm soil dry weight, while a commercial bio
View details →Negative / Null Result ReportOpen accessPsychology
Siqi Zhang, Ping Wang, Weichen Wang et al. · 2026 · Behavioral Sciences
Prosocial behavior is an important manifestation of socialization in young children. As the primary setting for socialization of young children, the family bears the significant responsibility of fostering prosocial behavior in young children. Drawing on family systems theory and Goleman’s emotional intelligence theory, the purpose of this study was to investigate the relationship between parenting styles and children’s prosocial behavior and the mediating role of children’s emotional intelligence in it. In this study, an online questionnaire was distributed to 869 young children’s parents usi
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