Negative / Null Result ReportOpen accessMedicine
Mary Dankbaar, Jelmer Alsma, Els E. H. Jansen et al. · 2015 · Advances in Health Sciences Education
Simulation games are becoming increasingly popular in education, but more insight in their critical design features is needed. This study investigated the effects of fidelity of open patient cases in adjunct to an instructional e-module on students' cognitive skills and motivation. We set up a three-group randomized post-test-only design: a control group working on an e-module; a cases group, combining the e-module with low-fidelity text-based patient cases, and a game group, combining the e-module with a high-fidelity simulation game with the same cases. Participants completed questionnaires
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Elizabeth Richardson, Jamie Pearce, Niamh Shortt et al. · 2017 · Environmental Research
INTRODUCTION: Poor mental health in childhood has implications for health and wellbeing in later life. Natural space may benefit children's social, emotional and behavioural development. We investigated whether neighbourhood natural space and private garden access were related to children's developmental change over time. We asked whether relationships differed between boys and girls, or by household educational status. METHODS: were modelled to quantify their independent contributions to SDQ score change over time. RESULTS: Private garden access was strongly related to most SDQ domains, while
View details →Negative / Null Result ReportOpen accessComputer Science
Peter E. Clark, Oren Etzioni, Tushar Khot et al. · 2016 · Proceedings of the AAAI Conference on Artificial Intelligence
What capabilities are required for an AI system to pass standard 4th Grade Science Tests? Previous work has examined the use of Markov Logic Networks (MLNs) to represent the requisite background knowledge and interpret test questions, but…
View details →Negative / Null Result ReportNeuroscience
Matthew J. Hollocks, Catherine R. G. Jones, Andrew Pickles et al. · 2014 · Autism Research
While high levels of anxiety and depression are now recognized as major co-occurring problems in children and young people with an autism spectrum disorder (ASD), research examining possible associations with individual differences in…
View details →Negative / Null Result ReportOpen accessComputer Science
Mary McGlohon, Natalie Glance, Zach Reiter · 2010 · Proceedings of the International AAAI Conference on Web and Social Media
Given a set of reviews of products or merchants from a wide range of authors and several reviews websites, how can we measure the true quality of the product or merchant? How do we remove the bias of individual authors or sources? How do…
View details →Negative / Null Result ReportOpen accessMedicine
Padhma Ranganathan, Paul A. Clark, John S. Kuo et al. · 2011 · Journal of Virology
Viruses are appreciated as etiological agents of certain human tumors, but the number of different cancer types induced or exacerbated by viral infections is unknown. Glioblastoma multiforme (GBM)/astrocytoma grade IV is a malignant and…
View details →Negative / Null Result ReportOpen accessDecision Sciences
M. Dachyar, Liska Banjarnahor · 2017 · Intangible Capital
Purpose: This study explores factors that influence consumer’s purchase intention at three consumer-to-consumer (C2C) e-commerce companies in Indonesia.Design/methodology/approach: 5 Expert opinions are used to determine the indicators of each factor and the Structural Equation Modelling (SEM) method is used to analyze the empirical data of 400 respondents for each company.Findings: It is found different significant factors that influence customer’s purchase intention in each company. Trust and risk are found to be significantly effect purchase intention in Company A. Meanwhile, the other two
View details →Replication FailurePsychology
Dermot Lynott, Katherine S. Corker, Jessica Wortman et al. · 2014 · Social Psychology
We report the results of three high-powered, independent replications of Study 2 from Williams and Bargh (2008) . Participants evaluated hot or cold instant therapeutic packs before choosing a reward for participation that was framed as a…
View details →Negative / Null Result ReportDentistry
Rachel Anner, Yoav Grossmann, Yael Anner et al. · 2010 · Implant Dentistry
OBJECTIVES: To evaluate the factors associated with long-term implant survival in a large cohort of patients in regular follow-up until data collection. METHODS: The study population consisted of 475 patients who were referred to a private…
View details →Negative / Null Result ReportOpen accessSocial Sciences
Shigeo Hirano, James M. Snyder, Stephen Ansolabehere et al. · 2010 · Quarterly Journal of Political Science
Many observers and scholars argue that primary elections contribute to ideological polarization in U.S. politics. We test this claim using congressional elections and roll call voting behavior. Many of our findings are null. We find little…
View details →Negative / Null Result ReportOpen accessPhysics and Astronomy
Ladan Arissian, Christopher Smeenk, F. Turner et al. · 2010 · Physical Review Letters
Tunneling is often used to describe multiphoton ionization of rare gas atoms in infrared fields. We test the tunneling approximation and its nonadiabatic extension by measuring the unperturbed momentum distribution along the κ direction of…
View details →Negative / Null Result ReportEconomics, Econometrics and Finance
Jill R. Horwitz, Brenna D. Kelly, John DiNardo · 2013 · Health Affairs
The Affordable Care Act encourages workplace wellness programs, chiefly by promoting programs that reward employees for changing health-related behavior or improving measurable health outcomes. Recognizing the risk that unhealthy employees…
View details →Negative / Null Result ReportOpen accessMedicine
Nicholas J. Short, Naval Daver, Courtney D. DiNardo et al. · 2024 · Journal of Clinical Oncology
PURPOSE Azacitidine plus venetoclax is a standard of care for patients with newly diagnosed AML who are unfit for intensive chemotherapy. However, FLT3 mutations are a common mechanism of resistance to this regimen. The addition of…
View details →Negative / Null Result ReportOpen accessMedicine
Zhongheng Zhang, Gensheng Zhang, Hemant Goyal et al. · 2018 · Critical Care
BACKGROUND AND OBJECTIVE: Sepsis is a heterogeneous disease and identification of its subclasses may facilitate and optimize clinical management. This study aimed to identify subclasses of sepsis and its responses to different amounts of fluid resuscitation. METHODS: This was a retrospective study conducted in an intensive care unit at a large tertiary care hospital. The patients fulfilling the diagnostic criteria of sepsis from June 1, 2001 to October 31, 2012 were included. Clinical and laboratory variables were used to perform the latent profile analysis (LPA). A multivariable logistic regr
View details →Negative / Null Result ReportEconomics, Econometrics and Finance
Scott Baker, Andrey Fradkin · 2017 · The Review of Economics and Statistics
Job search is a key choice variable in theories of labor markets but is difficult to measure directly. We develop a job search activity index based on Google search data, the Google Job Search Index (GJSI). We validate the GJSI with both…
View details →Negative / Null Result ReportNeuroscience
Jack D. Wang, El‐Sayed Khafagy, Khalil Khanafer et al. · 2016 · Molecular Pharmaceutics
The endothelial cells lining the capillaries supplying the brain with oxygen and nutrients form a formidable barrier known as the blood-brain barrier (BBB), which exhibits selective permeability to small drug molecules and virtually…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Wang Xi, Surabhi Sonam, Thuan Beng Saw et al. · 2017 · Nature Communications
Collective epithelial behaviors are essential for the development of lumens in organs. However, conventional assays of planar systems fail to replicate cell cohorts of tubular structures that advance in concerted ways on out-of-plane curved and confined surfaces, such as ductal elongation in vivo. Here, we mimic such coordinated tissue migration by forming lumens of epithelial cell sheets inside microtubes of 1-10 cell lengths in diameter. We show that these cell tubes reproduce the physiological apical-basal polarity, and have actin alignment, cell orientation, tissue organization, and migrat
View details →Negative / Null Result ReportBusiness, Management and Accounting
Zhongju Liao, Manting Zhang, Xiaopeng Wang · 2018 · Corporate Social Responsibility and Environmental Management
Abstract As more and more females join boards of directors, their decisions concerning environmental innovation have also become the focus of scholars. Based on the upper echelons theory, feminist caring theory, and social role theory,…
View details →Negative / Null Result ReportOpen accessSocial Sciences
Elizabeth Asiedu · 2014 · Journal of African Development
Abstract This paper examines whether foreign aid in education has a significant effect on growth in Sub-Saharan Africa. Our analysis covers 38 countries over the period 1990–2004 and we control for initial per capita income, inflation,…
View details →Failed Experiment Report
Tracy Hall, Min Zhang, David Bowes et al. · 2014 · ACM Transactions on Software Engineering and Methodology
We investigate the relationship between faults and five of Fowler et al.'s least-studied smells in code: Data Clumps, Switch Statements, Speculative Generality, Message Chains, and Middle Man. We developed a tool to detect these five…
View details →Negative / Null Result ReportOpen accessSocial Sciences
Stephen J. Macdonald, John Clayton · 2012 · Disability & Society
The aim of this article is to explore disability and the digital divide using a quantitative methodology. The research investigates what impact digital technologies have had in improving the life-chances for disabled people from deprived neighbourhoods in the northeast of England. The study explores how disabled people engage with digital and assistive technologies in order to overcome disabling barriers and social exclusion. Unfortunately, the analysis found no evidence that digital and assistive technologies had any impact on reducing social exclusion for disabled people. In fact, the resear
View details →Negative / Null Result ReportOpen accessMathematics
Valentijn M. T. de Jong, Marinus J.C. Eijkemans, Ben Van Calster et al. · 2019 · Statistics in Medicine
Multinomial Logistic Regression (MLR) has been advocated for developing clinical prediction models that distinguish between three or more unordered outcomes. We present a full-factorial simulation study to examine the predictive…
View details →Negative / Null Result ReportOpen accessMedicine
Ignacio Illán‐Gala, Alberto Lleó, Anna Karydas et al. · 2020 · Neurology
OBJECTIVE: To test the hypothesis that plasma total tau (t-tau) and neurofilament light chain (NfL) concentrations may have a differential role in the study of frontotemporal lobar degeneration syndromes (FTLD-S) and clinically diagnosed…
View details →Negative / Null Result ReportOpen accessPhysics and Astronomy
B. P. Abbott, R. Abbott, T. D. Abbott et al. · 2019 · Physical review. D/Physical review. D.
We present results of an all-sky search for continuous gravitational waves (CWs), which can be produced by fast-spinning neutron stars with an asymmetry around their rotation axis, using data from the second observing run of the Advanced…
View details →Negative / Null Result ReportOpen accessMedicine
Andrea B. Apolo, Karla V. Ballman, Guru Sonpavde et al. · 2024 · New England Journal of Medicine
BACKGROUND: Muscle-invasive urothelial carcinoma is an aggressive disease with high rates of relapse. Whether pembrolizumab as adjuvant therapy would be effective in patients with high-risk muscle-invasive urothelial carcinoma after…
View details →Negative / Null Result ReportOpen accessMedicine
Xiaoyi Huang, Jian Zhao, Jinyi Bai et al. · 2019 · Journal of bone oncology
Osteosarcoma is the most common primary sarcoma of the bone. Lung osteosarcoma metastases at diagnosis have a significantly poor prognosis, even when surgery plus chemotherapy are performed. Our goal was to analyze clinical and sarcoma…
View details →Negative / Null Result ReportOpen accessEconomics, Econometrics and Finance
Maarten R.C. van Oordt, Chen Zhou · 2016 · Journal of Financial and Quantitative Analysis
Abstract We test for the presence of a systematic tail risk premium in the cross section of expected returns by applying a measure of the sensitivity of assets to extreme market downturns, the tail beta. Empirically, historical tail betas…
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Zorana Jovanovic Andersen, Massimo Stafoggia, Gudrun Weinmayr et al. · 2017 · Environmental Health Perspectives
BACKGROUND: Epidemiological evidence on the association between ambient air pollution and breast cancer risk is inconsistent. OBJECTIVE: We examined the association between long-term exposure to ambient air pollution and incidence of postmenopausal breast cancer in European women. METHODS: ); traffic intensity; and elemental composition of PM. We estimated cohort-specific associations between breast cancer and air pollutants using Cox regression models, adjusting for major lifestyle risk factors, and pooled cohort-specific estimates using random-effects meta-analyses. RESULTS: =0.04]. CONCLUSI
View details →Negative / Null Result ReportOpen accessMedicine
Clara Montagut, Guillem Argilés, Fortunato Ciardiello et al. · 2018 · JAMA Oncology
IMPORTANCE: Acquired resistance to anti-EGFR therapy (epidermal growth factor receptor) is frequently due to RAS and EGFR extracellular domain (ECD) mutations in metastatic colorectal cancer (mCRC). Some anti-EGFR-refractory patients…
View details →Negative / Null Result ReportOpen accessHealth Professions
Jahidur Rahman Khan, Nabil Awan, Md. Mazharul Islam et al. · 2020 · Frontiers in Public Health
Background The rapid growth in cases of COVID-19 has challenged national healthcare capacity, testing systems at an advanced ICU, and public health infrastructure level. This global study evaluates the association between multi-factorial healthcare capacity and case fatality of COVID-19 patients by adjusting for demographic, health expenditure, population density and prior burden of noncommunicable disease. It also explores the impact of government relationships with civil society as a predictor of infection and mortality rates. Methods Data were extracted from the Johns Hopkins University dat
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