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Browse the failure-mode index

21,665 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Survival rates and prognostic factors for infiltrating salivary duct carcinoma: Analysis of 228 cases from the Surveillance, Epidemiology, and End Results database

Vijayvel Jayaprakash, Mihai Merzianu, Graham Warren et al. · 2013 · Head & Neck

BACKGROUND: The survival rates and prognostic factors for salivary duct carcinoma (SDC) are not clear. METHODS: Survival estimates and prognostic factors were evaluated for 228 patients with SDC identified from the Surveillance,…

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Negative / Null Result ReportOpen accessAgricultural and Biological Sciences

Impacts of the changing climate on agricultural productivity and food security: Evidence from Ethiopia

Ahmed Bouteska, Taimur Sharif, Faruk Bhuiyan et al. · 2024 · Journal of Cleaner Production

This study investigates the influence of climate change on agriculture productivity and food security in the context of Ethiopia. We use 2011–2020 state level data set of four major seasonal crops of Cash and Food in Ethiopia, namely, barley, wheat, maize, and sorghum. Methodologically, we apply the productivity function and the Ricardian approaches in the modelling for simulating the association of climate change with agriculture productivity. This study documents the interconnectedness among changes in climate, security of food and agriculture, indicating how the prior changes bring the latt

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Negative / Null Result ReportMedicine

Randomized Clinical Trial of Sodium Polystyrene Sulfonate for the Treatment of Mild Hyperkalemia in CKD

Laurence Lepage, A Dufour, Jessica Doiron et al. · 2015 · Clinical Journal of the American Society of Nephrology

BACKGROUND AND OBJECTIVES: Hyperkalemia affects up to 10% of patients with CKD. Sodium polystyrene sulfonate has long been prescribed for this condition, although evidence is lacking on its efficacy for the treatment of mild hyperkalemia…

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Negative / Null Result ReportOpen accessMedicine

An experimental study on the effects of a simulation game on students’ clinical cognitive skills and motivation

Mary Dankbaar, Jelmer Alsma, Els E. H. Jansen et al. · 2015 · Advances in Health Sciences Education

Simulation games are becoming increasingly popular in education, but more insight in their critical design features is needed. This study investigated the effects of fidelity of open patient cases in adjunct to an instructional e-module on students' cognitive skills and motivation. We set up a three-group randomized post-test-only design: a control group working on an e-module; a cases group, combining the e-module with low-fidelity text-based patient cases, and a game group, combining the e-module with a high-fidelity simulation game with the same cases. Participants completed questionnaires

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Negative / Null Result ReportOpen accessEnvironmental Science

The role of public and private natural space in children's social, emotional and behavioural development in Scotland: A longitudinal study

Elizabeth Richardson, Jamie Pearce, Niamh Shortt et al. · 2017 · Environmental Research

INTRODUCTION: Poor mental health in childhood has implications for health and wellbeing in later life. Natural space may benefit children's social, emotional and behavioural development. We investigated whether neighbourhood natural space and private garden access were related to children's developmental change over time. We asked whether relationships differed between boys and girls, or by household educational status. METHODS: were modelled to quantify their independent contributions to SDQ score change over time. RESULTS: Private garden access was strongly related to most SDQ domains, while

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Negative / Null Result ReportOpen accessComputer Science

Combining Retrieval, Statistics, and Inference to Answer Elementary Science Questions

Peter E. Clark, Oren Etzioni, Tushar Khot et al. · 2016 · Proceedings of the AAAI Conference on Artificial Intelligence

What capabilities are required for an AI system to pass standard 4th Grade Science Tests? Previous work has examined the use of Markov Logic Networks (MLNs) to represent the requisite background knowledge and interpret test questions, but…

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Negative / Null Result ReportNeuroscience

The Association Between Social Cognition and Executive Functioning and Symptoms of Anxiety and Depression in Adolescents With Autism Spectrum Disorders

Matthew J. Hollocks, Catherine R. G. Jones, Andrew Pickles et al. · 2014 · Autism Research

While high levels of anxiety and depression are now recognized as major co-occurring problems in children and young people with an autism spectrum disorder (ASD), research examining possible associations with individual differences in…

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Negative / Null Result ReportOpen accessComputer Science

Star Quality: Aggregating Reviews to Rank Products and Merchants

Mary McGlohon, Natalie Glance, Zach Reiter · 2010 · Proceedings of the International AAAI Conference on Web and Social Media

Given a set of reviews of products or merchants from a wide range of authors and several reviews websites, how can we measure the true quality of the product or merchant? How do we remove the bias of individual authors or sources? How do…

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Negative / Null Result ReportOpen accessDecision Sciences

Factors influencing purchase intention towards consumer-to-consumer e-commerce

M. Dachyar, Liska Banjarnahor · 2017 · Intangible Capital

Purpose: This study explores factors that influence consumer’s purchase intention at three consumer-to-consumer (C2C) e-commerce companies in Indonesia.Design/methodology/approach: 5 Expert opinions are used to determine the indicators of each factor and the Structural Equation Modelling (SEM) method is used to analyze the empirical data of 400 respondents for each company.Findings: It is found different significant factors that influence customer’s purchase intention in each company. Trust and risk are found to be significantly effect purchase intention in Company A. Meanwhile, the other two

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Negative / Null Result ReportDentistry

Smoking, Diabetes Mellitus, Periodontitis, and Supportive Periodontal Treatment as Factors Associated With Dental Implant Survival: A Long-Term Retrospective Evaluation of Patients Followed for Up to 10 Years

Rachel Anner, Yoav Grossmann, Yael Anner et al. · 2010 · Implant Dentistry

OBJECTIVES: To evaluate the factors associated with long-term implant survival in a large cohort of patients in regular follow-up until data collection. METHODS: The study population consisted of 475 patients who were referred to a private…

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Negative / Null Result ReportOpen accessSocial Sciences

Primary Elections and Partisan Polarization in the U.S. Congress

Shigeo Hirano, James M. Snyder, Stephen Ansolabehere et al. · 2010 · Quarterly Journal of Political Science

Many observers and scholars argue that primary elections contribute to ideological polarization in U.S. politics. We test this claim using congressional elections and roll call voting behavior. Many of our findings are null. We find little…

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Negative / Null Result ReportOpen accessPhysics and Astronomy

Direct Test of Laser Tunneling with Electron Momentum Imaging

Ladan Arissian, Christopher Smeenk, F. Turner et al. · 2010 · Physical Review Letters

Tunneling is often used to describe multiphoton ionization of rare gas atoms in infrared fields. We test the tunneling approximation and its nonadiabatic extension by measuring the unperturbed momentum distribution along the κ direction of…

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Negative / Null Result ReportOpen accessMedicine

Identification of subclasses of sepsis that showed different clinical outcomes and responses to amount of fluid resuscitation: a latent profile analysis

Zhongheng Zhang, Gensheng Zhang, Hemant Goyal et al. · 2018 · Critical Care

BACKGROUND AND OBJECTIVE: Sepsis is a heterogeneous disease and identification of its subclasses may facilitate and optimize clinical management. This study aimed to identify subclasses of sepsis and its responses to different amounts of fluid resuscitation. METHODS: This was a retrospective study conducted in an intensive care unit at a large tertiary care hospital. The patients fulfilling the diagnostic criteria of sepsis from June 1, 2001 to October 31, 2012 were included. Clinical and laboratory variables were used to perform the latent profile analysis (LPA). A multivariable logistic regr

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Negative / Null Result ReportNeuroscience

Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidicin VitroModel of the Blood–Brain Barrier

Jack D. Wang, El‐Sayed Khafagy, Khalil Khanafer et al. · 2016 · Molecular Pharmaceutics

The endothelial cells lining the capillaries supplying the brain with oxygen and nutrients form a formidable barrier known as the blood-brain barrier (BBB), which exhibits selective permeability to small drug molecules and virtually…

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Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology

Emergent patterns of collective cell migration under tubular confinement

Wang Xi, Surabhi Sonam, Thuan Beng Saw et al. · 2017 · Nature Communications

Collective epithelial behaviors are essential for the development of lumens in organs. However, conventional assays of planar systems fail to replicate cell cohorts of tubular structures that advance in concerted ways on out-of-plane curved and confined surfaces, such as ductal elongation in vivo. Here, we mimic such coordinated tissue migration by forming lumens of epithelial cell sheets inside microtubes of 1-10 cell lengths in diameter. We show that these cell tubes reproduce the physiological apical-basal polarity, and have actin alignment, cell orientation, tissue organization, and migrat

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Negative / Null Result ReportBusiness, Management and Accounting

Do female directors influence firms' environmental innovation? The moderating role of ownership type

Zhongju Liao, Manting Zhang, Xiaopeng Wang · 2018 · Corporate Social Responsibility and Environmental Management

Abstract As more and more females join boards of directors, their decisions concerning environmental innovation have also become the focus of scholars. Based on the upper echelons theory, feminist caring theory, and social role theory,…

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Failed Experiment Report

Some Code Smells Have a Significant but Small Effect on Faults

Tracy Hall, Min Zhang, David Bowes et al. · 2014 · ACM Transactions on Software Engineering and Methodology

We investigate the relationship between faults and five of Fowler et al.'s least-studied smells in code: Data Clumps, Switch Statements, Speculative Generality, Message Chains, and Middle Man. We developed a tool to detect these five…

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Negative / Null Result ReportOpen accessSocial Sciences

Back to the future, disability and the digital divide

Stephen J. Macdonald, John Clayton · 2012 · Disability & Society

The aim of this article is to explore disability and the digital divide using a quantitative methodology. The research investigates what impact digital technologies have had in improving the life-chances for disabled people from deprived neighbourhoods in the northeast of England. The study explores how disabled people engage with digital and assistive technologies in order to overcome disabling barriers and social exclusion. Unfortunately, the analysis found no evidence that digital and assistive technologies had any impact on reducing social exclusion for disabled people. In fact, the resear

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Negative / Null Result ReportOpen accessPhysics and Astronomy

All-sky search for continuous gravitational waves from isolated neutron stars using Advanced LIGO O2 data

B. P. Abbott, R. Abbott, T. D. Abbott et al. · 2019 · Physical review. D/Physical review. D.

We present results of an all-sky search for continuous gravitational waves (CWs), which can be produced by fast-spinning neutron stars with an asymmetry around their rotation axis, using data from the second observing run of the Advanced…

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