21,733 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Liang H, Zhang D, An X et al. · 2026 · Preprint
Abstract The rise of generative AI (GenAI) has sparked interest in whether human-AI collaboration can enhance creativity, yet empirical findings remain mixed. This study systematically compared 4 collaboration models (i.e., AI-first,…
View details →Gupta N, Seo J, Phan F et al. · 2026 · Heart rhythm
Background Lead dwell time (DT) is associated with increased complexity of cardiac implantable electronic device (CIED) extraction. Optimal strategies for risk mitigation are not well studied. Objective This study aimed to evaluate the…
View details →Chen YF, Kou HW, Chen TH et al. · 2026 · Journal of gastrointestinal cancer
Purpose Radical surgery is the primary treatment for localized gastric cancer (GC), but the benefit of adjuvant chemotherapy in stage IB GC remains unclear. This study evaluates its impact on recurrence and survival post-gastrectomy.…
View details →Andrade A, Mureb M, Karaman N et al. · 2026 · Journal of neuro-oncology
PURPOSE: KRAS G12C mutations occur in approximately 11% of non-small-cell lung cancer (NSCLC) patients and are associated with aggressive disease and poor prognosis. Although KRAS G12C-inhibitors are now approved, their impact on Gamma…
View details →Mikami R, Imai S, Hayakawa M et al. · 2025 · Die Pharmazie
This study aimed to evaluate the temporal effect of a serum creatinine (SCr) correction intervention in critically ill patients with daily muscle wasting. A total of 5,355 critical care days in 574 patients with creatinine clearance (Clcr)…
View details →Montenegro J, Oliveira CL, Nguyen NK et al. · 2026 · The Journal of nutrition
Background Excess body weight is associated with chronic low-grade inflammation and metabolic abnormalities, such as insulin resistance, and dyslipidemia. Objectives This study aimed to assess the impact of a soy protein-yogurt-honey…
View details →Bliesner RK, Stevens AA, Holling L et al. · 2026 · Cureus
Background Being in the large majority, right-handed people are not required to use their nondominant hands throughout their daily lives, resulting in a loss of motor dexterity. As technology continues to advance, improving motor dexterity…
View details →Oscorbin IP, Smertina MA, Kunova MS et al. · 2025 · Preprint
The metal-binding periplasmic protein CusF has been proposed as a bifunctional tag enhancing solubility of recombinant proteins and enabling purification using Cu affinity chromatography. However, evidence for its performance remains…
View details →Nascimento GO, Otávio KS, Ferreira J et al. · 2026 · Tropical animal health and production
Bioactive peptides (BP) have been investigated as potential functional feed additives due to their reported immunomodulatory and metabolic properties. This study evaluated the effects of dietary BP supplementation on growth performance,…
View details →Talathi R, Hubbard RA, Somasundar P et al. · 2026 · Surgery
Background The Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma (STRASS 2) trial is evaluating the impact of neoadjuvant chemotherapy versus surgery in patients with high-risk, resectable…
View details →Zhao A, Chen W, Liang Y et al. · 2026 · Cancer treatment and research communications
Objective To compare and analyze the efficacy and safety of an overall strategy of immunotherapy combined with chemoradiotherapy in patients with limited-stage small cell lung cancer (LS-SCLC)-including induction immunotherapy plus…
View details →Sarica C, Darmani G, Ramezanpour H et al. · 2026 · Science translational medicine
Transcranial ultrasound stimulation (TUS) is a promising noninvasive technique for modulating deep brain targets and circuits with high spatial precision. For its successful clinical translation, confirmation of target engagement, together…
View details →Riestra JM, Levin-Carrion Y, Sutar R et al. · 2026 · Human psychopharmacology
Treatment-resistant depression (TRD) remains a formidable challenge in psychiatry, with nearly one-third of patients with major depressive disorder (MDD) failing to respond adequately to first-line pharmacological treatments.…
View details →Nandi D, Gajarski RJ, Zhao H et al. · 2026 · Pediatric transplantation
Purpose Human Leukocyte Antigen (HLA) sensitization can adversely impact heart transplant (HTx) outcomes. We evaluated the effect of panel-reactive antibody (PRA) and desensitization (DS) strategies on outcomes of pediatric HTx recipients…
View details →Silva-García J, Eurolo I, Fuentes-Flores R et al. · 2026 · Brain research
Ischemic stroke is a leading cause of death and disability worldwide. Among survivors, one-third live with permanent impairments, and two-thirds experience upper limb dysfunction. Despite advances in acute care, no universally effective…
View details →Hayashi T, Go M, Kawasumi K et al. · 2026 · Preprint
Abstract Introduction Maintaining dose intensity is essential for the efficacy of adjuvant S-1 chemotherapy in gastric cancer. Although pharmacist interventions can reduce toxicity and improve adherence, multicenter evidence regarding…
View details →Saloojee H, Gramanie MC, Mwale R et al. · 2026 · Medical teacher
Background Generative artificial intelligence (AI) tools are entering clinical training faster than curricula and assessments can adapt. It is currently unknown whether point-of-care access to large language models (LLMs) improves…
View details →An DW, Wang Y, Cheng YB et al. · 2026 · Hypertension (Dallas, Tex. : 1979)
Background Whether central systolic blood pressure (cSBP) compared with brachial systolic blood pressure (bSBP) improves risk stratification remains debated. This study investigated whether cSBP is more closely associated with total and…
View details →Durmuş Ece BŞ, Yozgat Z, Işık MU et al. · 2026 · Journal francais d'ophtalmologie
Purpose To determine the effect of trabecular meshwork (TM) peeling on gonioscopy-assisted transluminal trabeculotomy (GATT) surgical outcomes in patients with open-angle glaucoma. Methods In this retrospective cross-sectional study,…
View details →Forville H, Coppla FM, Naupari-Villasante R et al. · 2026 · Journal of dentistry
Objective To evaluate whether dentin airborne-particle abrasion (APA) with aluminum oxide affects the retention and clinical performance of composite resin restorations in non-carious cervical lesions (NCCLs). Methods This prospective,…
View details →Vedrenne-Cloquet M, de Montmollin E, Gaudemer A et al. · 2026 · Journal of educational evaluation for health professions
Purpose To assess the effectiveness of a short multimodal workshop, including stress-management and communication-skills training, on objective structured clinical examination (OSCE) performance and exam-related anxiety among medical…
View details →Tortajada M, Rodriguez-Larios J, Martínez-Pérez V et al. · 2026 · Preprint
Recent findings have shown the influential role of theta-gamma cross-frequency coupling in the maintenance of items in Working Memory (WM). Specifically, it has been proposed that individual items are represented within gamma oscillations…
View details →Badulescu S, Gill H, Shah H et al. · 2026 · Med (New York, N.Y.)
Background Evidence suggests that glucagon-like peptide 1 receptor agonists (GLP-1RAs) might have pro-cognitive effects. No prior study has evaluated the efficacy and safety of a GLP-1RA for the treatment of cognitive dysfunction in adults…
View details →Muller M, Agrawal A, Thomas N et al. · 2026 · Substance use & addiction journal
Background Patients with opioid use disorder (OUD) are frequently hospitalized and often need post-acute care, but face high rates of rejection from post-acute and long-term care (PALTC) facilities. This study aimed to assess the impact of…
View details →Munazir M, Kausar N, Qureshi R et al. · 2026 · Scientific reports
Untreated municipal wastewater is widely used for irrigation in peri-urban agriculture where freshwater is limited, yet its effects on edible vegetable crops remain context dependent. This study evaluated the morphological, physiological,…
View details →Liang XQ, Han L, Yan T et al. · 2026 · Journal of anesthesia
Purpose Postoperative pulmonary complications are common and associated with worse long-term outcomes. In our previous trial, prophylactic penehyclidine inhalation reduced pulmonary complications in high-risk patients. Herein, we tested…
View details →Toft M, Hansen MS, Vestergaard JD et al. · 2026 · British journal of sports medicine
Objective To evaluate whether individualised treatment using the Copenhagen Achilles Rupture Treatment Algorithm (CARTA) is superior to default operative or non-operative strategies. Methods We conducted a multicentre, three-arm,…
View details →Chau IJ, Dixon PR, Lin V et al. · 2026 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Objective To identify patient characteristics associated with improvements in speech recognition scores (SRS) and Cochlear Implant Quality of Life (CIQOL-35) scores following cochlear implantation. Study design Multi-institutional…
View details →Peters S, Tan DSW, Gerber DE et al. · 2026 · Nature cancer
Over 50% of persons with unresectable stage III non-small cell lung cancer (NSCLC) treated with standard-of-care concurrent chemoradiotherapy (CCRT) and durvalumab consolidation progress or die within 18 months. Here adults with untreated,…
View details →Schulz JV, Doerflinger JT, Behm C et al. · 2026 · Health psychology : official journal of the Division of Health Psychology, American Psychological Association
Objective This study compares three models of parental human papillomavirus (HPV) vaccination intentions across United States, United Kingdom, and Germany: A model based on the theory of planned behavior (TPB), a model incorporating…
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