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Negative / Null Result ReportOpen accessInfectious and parasitic diseases

Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study

Chiu Rossa WK; Chim Stephen SC; Wu Alan KL; Chung Grace TY; Hui David SC; Tang Nelson LS; Chan KC Allen; Lee Nelson · 2005 · BMC Infectious Diseases

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Abstract Background It has been postulated that genetic predisposition may influence the susceptibility to SARS-coronavirus infection and disease outcomes. A recent study has suggested that the deletion allele (D allele) of the angiotensin converting enzyme ( ACE ) gene is associated with hypoxemia in SARS patients. Moreover, the ACE D allele has been shown to be more prevalent in patients suffering from adult respiratory distress syndrome (ARDS) in a previous study. Thus, we have investigated the association between ACE insertion/deletion (I/D) polymorphism and the progression to ARDS or requ

Abstract by Chiu Rossa WK; Chim Stephen SC; Wu Alan KL; Chung Grace TY; Hui David SC; Tang Nelson LS; Chan KC Allen; Lee Nelson, BMC Infectious Diseases (2005) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1186/1471-2334-5-26