Negative / Null Result ReportOpen accessComputer Science
Rabab Ali Abumalloh, Mehrbakhsh Nilashi, Osama Halabi et al. · 2024 · Journal of Innovation & Knowledge
Recommendation agents (RAs) have proven to be effective decision-making tools for customers, as they can boost trust and loyalty when customers shop online. They can analyse large amounts of data using machine learning algorithms and…
View details →Negative / Null Result ReportOpen accessMaterials Science
Malek Msheik, Sylvain Rodat, Stéphane Abanades · 2024 · Journal of Analytical and Applied Pyrolysis
Solar methane pyrolysis in different molten media and reactor configurations was experimented to improve hydrogen production . Pure Sn, Ni 0.18 Sn 0.82 , Cu 0.45 Bi 0.55 , and KCl melts were compared at three different temperatures…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Celia Sequera, Margherita Grattarola, Floriane Cannet et al. · 2025 · Nature Communications
Histone deacetylases (HDACs) are epigenetic regulators frequently altered in cancer. Here we report that overexpression of HDAC1/2 occurs in Hepatocellular Carcinoma (HCC) patients, correlating with poor prognosis. We show that romidepsin,…
View details →Negative / Null Result ReportOpen accessComputer Science
Catriona L. Scrivener, Tijl Grootswagers, Alexandra Woolgar · 2026 · European Journal of Neuroscience
Multivariate pattern analysis (MVPA) is a popular technique that can distinguish between condition-specific patterns of activation. Applied to neuroimaging data, MVPA decoding for inference uses above chance decoding to identify statistically robust condition-specific information in neuroimaging data, which may be missed by univariate methods. However, several analysis choices influence decoding results, and the combined effects of these choices have not been fully evaluated. In particular, an increasingly popular approach is to average data from several trials together before training an MVPA
View details →Negative / Null Result ReportBiochemistry, Genetics and Molecular Biology
Luca‐Cesare Blawitzki, Nina Bartels, Lorand Bonda et al. · 2024 · Biomacromolecules
The glycocalyx, a complex carbohydrate layer on cell surfaces, plays a crucial role in various biological processes. Understanding native glycocalyces' complexity is challenging due to their intricate and dynamic nature. Simplified mimics…
View details →Negative / Null Result ReportPsychology
Olga Perepelkina, Maria Boboleva, Галина Арина et al. · 2017 · Multisensory Research
The aim of the study was to investigate how emotion information processing factors, such as alexithymia and emotional intelligence, modulate body ownership and influence multisensory integration during the ‘rubber hand illusion’ (RHI)…
View details →Negative / Null Result Report
Fabio Bovenga, Guido Pasquariello, Alberto Refice · 2021 · Remote Sensing
Current multi-temporal interferometric Synthetic Aperture Radar (MTInSAR) datasets cover long time periods with regular temporal sampling. This allows high-rate and non-linear trends to be observed, which typically characterize pre-failure…
View details →Negative / Null Result ReportSocial Sciences
Branden B. Johnson, Marcus Mayorga · 2020 · Human and Ecological Risk Assessment An International Journal
Cross-sectional surveys, despite their value, are unable to probe dynamics of risk perceptions over time. An earlier longitudinal panel study of Americans’ views on Ebola risk inspired this partial replication on Americans’ views of Zika…
View details →Negative / Null Result ReportOpen accessEngineering
Khuzairi Masrakin, Hasliza A. Rahim, Ping Jack Soh et al. · 2019 · IEEE Access
This paper presents the assessment of short-term wireless body area network (WBAN) exposure, which is operated at the industrial, scientific, and medical (ISM) band (2.45 GHz) in the vicinity of the human body. The experiment utilizes two popular textile antenna topologies, a planar monopole and a patch antenna as the radiating sources. The objective of this experiment is to investigate whether the exposure from WBAN may influence the physiological parameters (body temperature, blood pressure, and heart rate) and the well-being of the wearer. Counter-balanced, crossover, and the single-blind m
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Barbara Smith, Dan Carpenter, J. M. Holland et al. · 2023 · Journal of Applied Ecology
Abstract Lowland heath is a priority habitat for conservation, nowadays largely managed for biodiversity. Historically, prescribed burning has been the principal management tool, but there are increasing calls to substitute burning with cutting to improve biodiversity outcomes. However, poor understanding of potential impacts compromises decision making. Our study was carried out in the New Forest National Park, the largest area of lowland heath in Europe. Using a multi‐trophic approach, we compared the ecological impact of prescribed burning with two types of vegetation cutting (swiping and b
View details →Negative / Null Result ReportOpen accessSocial Sciences
Penny Holding, Amina Abubakar, Elizabeth Obiero et al. · 2011
The aim of this paper is to describe the adaptations made to the Infant-Toddler version of the Home Observation Measure of the Environment for use in a low income Kenyan population. A total of 425 (214 girls) children aged 6-35 months were…
View details →Negative / Null Result ReportOpen accessNeuroscience
Thomas Cope, Manon Grube, Arnab Mandal et al. · 2014 · Neuropsychologia
Bilateral, high-frequency stimulation of the basal ganglia (STN-DBS) is in widespread use for the treatment of the motor symptoms of Parkinson׳s disease (PD). We present here the first psychophysical investigation of the effect of STN-DBS upon perceptual timing in the hundreds of milliseconds range, with both duration-based (absolute) and beat-based (relative) tasks; 13 patients with PD were assessed with their STN-DBS 'on', 'off', and then 'on' again. Paired parametric analyses revealed no statistically significant differences for any task according to DBS status. We demonstrate, from the exa
View details →Null DatasetOpen accessNeuroscience
Cyril Pernet, Christopher R. Madan · 2019 · European Journal of Neuroscience
Tomographic imaging (i.e. magnetic resonance imaging [MRI], positron emission tomography [PET], X-ray computed tomography [CT]) offers a unique window in understanding structure-function relationships in the living brain. Nowadays, it is standard practice to acquire entire brain volumes and perform statistical analyses at each voxel, an approach known as statistical parametric mapping (Friston, Frith, Liddle, & Frackowiak, 1991). Because it is impossible to report the statistical results in every voxel, summary tables and figures are of importance. The choice made by authors to create such fig
View details →Negative / Null Result ReportOpen accessImmunology and Microbiology
Alex B. Kleinpeter, Donna L. Mallery, Nadine Renner et al. · 2024 · Nature Communications
The HIV-1 capsid is composed of capsid (CA) protein hexamers and pentamers (capsomers) that contain a central pore hypothesised to regulate capsid assembly and facilitate nucleotide import early during post-infection. These pore functions are mediated by two positively charged rings created by CA Arg-18 (R18) and Lys-25 (K25). Here we describe the forced evolution of viruses containing mutations in R18 and K25. Whilst R18 mutants fail to replicate, K25A viruses acquire compensating mutations that restore nearly wild-type replication fitness. These compensating mutations, which rescue reverse t
View details →Negative / Null Result ReportMedicine
Jing Luo, Zheng Dong, Hui Xie et al. · 2022 · Liver International
BACKGROUND & AIMS: Management of elderly patients with hepatocellular carcinoma (HCC) has become a major concern. Some data suggest that cryoablation improves the outcomes of elderly patients with HCC, but its efficacy and safety remain…
View details →Failed Experiment ReportPhysics and Astronomy
Prabir Kumar Haldar, Sanjib Kumar Manna · 2011 · Chinese Physics Letters
We present an analysis of ring-like and jet-like events in terms of factorial correlations and oscillatory multiplicity moments of 32S-Ag/Br interactions at 200 A GeV. The investigation reveals that the correlated moments increase with…
View details →Replication FailureOpen accessMedicine
Yitao Zheng, Yan‐Jun Xiang, Hongqi Shi et al. · 2024 · Journal of Hepatocellular Carcinoma
Purpose: Combining transarterial chemoembolization (TACE) with systemic therapy has shown significant efficacy for intermediate-stage hepatocellular carcinoma (HCC) patients. This study aimed to validate the therapeutic efficacy of TACE…
View details →Negative / Null Result ReportOpen accessPsychology
Hanno Andreas Ohmann, Niclas Kuper, Jan Wacker · 2022 · PLoS ONE
The Effort-Expenditure for Rewards Task (EEfRT) has gained validity evidence from several studies. However, various modifications have been applied to the original version, which have never been compared systematically. In Study 1, we tested 120 healthy participants to directly compare two versions of the EEfRT. In Study 2, we tested a larger sample of 394 healthy participants to further examine the original EEfRT. We replicated the split-half reliability of both task versions. However, self-reported personality traits (e.g., trait BAS) correlated with only some task performance parameters in
View details →Negative / Null Result ReportOpen accessNeuroscience
Ian C. Fiebelkorn · 2021 · European Journal of Neuroscience
Recent research suggests that environmental sampling is a fundamentally rhythmic process (Benedetto et al., 2019; Fiebelkorn & Kastner, 2019; Schroeder et al., 2010). In primates, both attention-related sampling and exploratory eye…
View details →Negative / Null Result Report
Martin S. Davey, Eoghan T. Hurley, Tom R. Doyle et al. · 2022 · The American Journal of Sports Medicine
Background: Debate centering on the management of anterior shoulder instability (ASI) in recent years has led to many randomized controlled trials (RCTs) being published on the topic. The fragility index (FI) has subsequently emerged as a…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Stella Aslibekyan, Hassan S. Dashti, Toshiko Tanaka et al. · 2014 · Chronobiology International
Sunlight exposure has been shown to alter DNA methylation patterns across several human cell-types, including T-lymphocytes. Since epigenetic changes establish gene expression profiles, changes in DNA methylation induced by sunlight…
View details →Negative / Null Result ReportOpen accessNeuroscience
Anne Krogh Nøhr, Morten Lindow, Annika Forsingdal et al. · 2021 · Neuropsychopharmacology
A better understanding of the biological factors underlying antidepressant treatment in patients with major depressive disorder (MDD) is needed. We perform gene expression analyses and explore sources of variability in peripheral blood related to antidepressant treatment and treatment response in patients suffering from recurrent MDD at baseline and after 8 weeks of treatment. The study includes 281 patients, which were randomized to 8 weeks of treatment with vortioxetine (N = 184) or placebo (N = 97). To our knowledge, this is the largest dataset including both gene expression in blood and pl
View details →Negative / Null Result ReportOpen accessNeuroscience
Kaiwen Cheng, Aolin Ding, Lianfang Jiang et al. · 2019 · Frontiers in Human Neuroscience
Previous studies have demonstrated the automatic vigilance effect for faces and pictures and have attributed it to the brain's prioritized unconscious evaluation of early evolutionary stimuli that are critical to survival. Whether this effect exists for evolutionarily more recent stimuli, such as written words, has become the center of much debate. Apparently contradicting results have been reported in different languages, such as Hebrew, English, and Traditional Chinese (TC), with regard to the unconscious processing of emotional words in breaking continuous flash suppression (b-CFS). Our cur
View details →Negative / Null Result ReportOpen accessNeuroscience
Kelly L. Whiteford, Lucas S. Baltzell, Matt Chiu et al. · 2025 · Nature Communications
Musical training has been reported to be associated with enhanced neural processing of sounds, as measured via the frequency following response (FFR), implying the potential for human subcortical neural plasticity. We conducted a…
View details →Failed Experiment Report
Yike Liu, Degang Jin, Xu Chang et al. · 2010 · Geophysics
Abstract Surface-related multiple elimination (SRME) typically consists of two steps: The first step is prediction and the second step is subtraction. In subtraction, it is important to effectively attenuate multiple events and preserve…
View details →Negative / Null Result ReportOpen accessMathematics
Christian Bokhove · 2022 · Educational Research and Evaluation
An article by Kim et al. from 2014 examined individual- and school-level variables affecting the information and communication technology (ICT) literacy level of Korean elementary school students, finding differential gender effects. In…
View details →Negative / Null Result ReportOpen accessNeuroscience
Klaus Oberauer · 2022 · Psychological Science
Some theorists argue that working memory is limited to a discrete number of items and that additional items are not encoded at all. Adam et al. (2017) presented evidence supporting this hypothesis: Participants reproduced visual features of up to six items in a self-chosen order. After the third or fourth response, error distributions were indistinguishable from guessing. I present four experiments with young adults (each N = 24) reexamining this finding. Experiment 1 presented items slowly and sequentially. Experiment 2 presented them simultaneously but longer than in the experiments of Adam
View details →Negative / Null Result Report
Minah Han, Jongduk Baek · 2020 · Physics in Medicine & Biology
Abstract The purpose of this study is implementation of an anthropomorphic model observer using a convolutional neural network (CNN) for signal-known-statistically (SKS) and background-known-statistically (BKS) detection tasks. We conduct…
View details →Negative / Null Result ReportOpen accessNeuroscience
Angelo Pirrone, Wen Wen, Sheng Li et al. · 2018 · Perception
Recent research has shown that adults and children with autism spectrum disorders have a more conservative decision criterion in perceptual decision making compared to neurotypical individuals, meaning that autistic participants prioritise…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
M Hayat, Wenlong Carl Chen, Chantal Babb de Villiers et al. · 2025 · Nature Communications
Abstract Genome-wide association studies (GWAS) have characterized the contribution of common variants to breast cancer (BC) risk in populations of European ancestry, however GWAS have not been reported in resident African populations. This GWAS included 2485 resident African BC cases and 1101 population matched controls. Two risk loci were identified, located between UNC13C and RAB27A on chromosome 15 (rs7181788, p = 1.01 × 10 −08 ) and in USP22 on chromosome 17 (rs899342, p = 4.62 × 10 −08 ). Several genome-wide significant signals were also detected in hormone receptor subtype analysis. The
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