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21,778 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessOphthalmology

Microkeratome versus manually dissected donor tissue for Descemet stripping endothelial keratoplasty: A randomized prospective study

Ritu Mali, Smruti R. Priyadarshini, Srikant K. Sahu et al. · 2024 · Indian Journal of Ophthalmology

Purpose: To compare the visual outcomes, postoperative complications, and graft asymmetry between precut and manually dissected donor tissues for Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet stripping endothelial keratoplasty (DSEK) procedures, respectively. Methods: Seventy eyes of 70 patients undergoing DSEK/DSAEK at a tertiary eyecare center in eastern India were included in this prospective randomized control study. The 70 eyes were divided equally into two groups. Group A (n = 35) and Group B (n = 35) underwent DSEK and DSAEK procedures, respectively. the ope

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Negative / Null Result ReportOpen accessInfectious and parasitic diseases

Measles IgG Antibodies: Is There a Protective Role in COVID 19 Pandemic?‎ ‎

Amira Al Balakosy, Mostafa Alfishawy, Omnia Elnabawy et al. · 2021 · Afro-Egyptian Journal of Infectious and Endemic Diseases

Background and study aim: Epidemiological data reported lower death rates of COVID-19 cases in countries with higher & ‎recent coverage by measles containing vaccines. In this study we aim to identify measles IgG titer ‎in COVID-19 patients & correlate it with disease severity‎‎‎‎. Patients and Method: ‎This is a Cross-sectional study where 78 patients admitted to Ain Shams University Quarantine ‎hospitals with positive PCR for SARS-CoV-2 were enrolled. All patients underwent ‎quantification of serum measles IgG titer. Then classified according to the COVID-19 severity ‎into mild, moderate and

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Negative / Null Result ReportOpen accessMedicine

Investigating the Relationship between Self-Directed Learning and E-Citizenship knowledge and its comparison between Students of University of Mazandaran and Babol University of Medical Sciences

fatemeh marhemati, reza mir arab razi, mostafa azizi · 2020 · آموزش پزشکی

Background and Objective: Creating and developing self-directed learning skills has become one of the goals of education in recent decades, and today's students need to learn and acquire comprehensive information in this regard, or better to say, learn information and communication technology skills, to Be able to use electronic services. The purpose of this study was to investigate the relationship between electronic citizenship knowledge and self-directed learning of students of University of Mazandaran and Babol University of medical sciences. Methods: This study is descriptive-analytical i

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Negative / Null Result ReportOpen accessPediatrics

Phenotypes, bedside examination, and video head impulse test in vestibular migraine of childhood compared with probable vestibular migraine and recurrent vertigo in childhood

Roberto Teggi, Bruno Colombo, Marco Familiari et al. · 2023 · Frontiers in Pediatrics

IntroductionVestibular impairment and vertigo in the pediatric population have an estimated prevalence ranging between 0.4% and 5.6% and are a topic of interest in recent years. The Bárány Society has recently reclassified migraine-related vertigo syndromes as vestibular migraine of childhood (VMC), probable vestibular migraine of childhood (probable VMC), and recurrent vertigo of childhood (RVC).MethodsApplying the criteria established by the Bárány Society, we retrospectively analyzed data on 95 pediatric patients suffering from episodic vertigo that were recruited from 2018 to 2022. In appl

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Negative / Null Result ReportOpen accessGynecology and obstetrics

The impact of epidural analgesia on delivery mode in Robson class 1 women: a retrospective cohort studyAJOG MFM at a Glance

Fedora Ambrosetti, MD, Giovanni Grandi, MD, Elisabetta Petrella, MD et al. · 2023 · AJOG Global Reports

BACKGROUND: The use of epidural analgesia represents the gold standard for pain management during labor, but the influence of the use of epidural analgesia on delivery mode is not fully understood. OBJECTIVE: This study aimed to analyze the impact of epidural analgesia on the delivery mode, namely, cesarean delivery, vaginal delivery, and operative vaginal delivery rates, in Robson class 1 women. STUDY DESIGN: A retrospective cohort study was conducted on all Robson class 1 women who delivered from January 1, 2019, to December 31, 2019, in the University Hospital of Modena. The primary outcome

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Negative / Null Result ReportOpen accessSports medicine

Hang cleans and hang snatches produce similar improvements in female collegiate athletes

JL Ayers, M DeBeliso, TG Sevene et al. · 2016 · Biology of Sport

Olympic weightlifting movements and their variations are believed to be among the most effective ways to improve power, strength, and speed in athletes. This study investigated the effects of two Olympic weightlifting variations (hang cleans and hang snatches), on power (vertical jump height), strength (1RM back squat), and speed (40-yard sprint) in female collegiate athletes. 23 NCAA Division I female athletes were randomly assigned to either a hang clean group or hang snatch group. Athletes participated in two workout sessions a week for six weeks, performing either hang cleans or hang snatc

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Negative / Null Result ReportOpen accessPsychology

PERBEDAAN PERILAKU KERJA INOVATIF BERDASARKAN KARAKTERISTIK INDIVIDU KARYAWAN

Arum Etikariena · 2019 · Jurnal Psikologi Undip

In recent years, research on innovation in organizations, particularly innovative work behaviors, has developed considerably. The objective of the study were to examine the role of individual characteristics such as age, gender, educational background, ethnic’s background, tenure and length in current position which presumably would have an impact on the formation of innovative work behaviors. The study is quantitative study with non-experimental design, conducted on 279 respondents working in a Syariah Bank and a television company. The measuring tool used is the Innovative Work Behavior Scal

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Negative / Null Result ReportOpen accessPsychology

Comparison of the effectiveness of exposure, mindfulness and mindfulness - integrated exposure on arak women obsessive - compulsive disorder

sara hasani, abolghasem mehrinezhad, Roshanak khodabakhsh pirkalani · 2020 · مجله علوم روانشناختی

Background: Obsessive-compulsive disorder is one of the most common and disabling psychological disorders. Many studies have investigated the effectiveness of mindfulness and exposure on the improvement of obsessive-compulsive disorder, but the key question is which of the two combinations of exposure, mindfulness, and mindfulness of exposure is most effective on obsessive-compulsive disorder in women? Aims: To compare the effects of exposure, mindfulness and mindfulness-exposure consciousness on combined obsessive-compulsive disorder in Arak women. Method: This was a quasi-experimental study

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Negative / Null Result ReportOpen accessMedicine

Comparison of polishing effects of three polishing systems on machinable composite resins

LIU Yanan, WANG Likai, LIU Sisi et al. · 2019 · 口腔疾病防治

Objective To compare the polishing effects of three different polishing systems on machinable compos⁃ ite resins and to provide a basis for the rational selection of polishing systems in the clinic. Methods Block HC, Cerasmart, and Hyramic were fabricated into 90 test pieces. Then, 30 test pieces for each material were randomly divid⁃ ed into 3 groups with 10 pieces per group. The pieces were polished with the Vita Enamic® Polishing Set (Vita group), EVE RA341 composite polishing set (Eve group), and Toboo M elastic ceramic polishing set (Tob group). The surface roughness and gloss of each tes

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Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system

Enhanced recovery in type A aortic dissection evaluating the efficacy and feasibility of early myocardial reperfusion

Tianyu Niu, Tianyu Niu, Zhishuo Liu et al. · 2025 · Frontiers in Cardiovascular Medicine

BackgroundThis study investigates the feasibility and early outcomes of early myocardial reperfusion in patients with type A aortic dissection (TAAD), evaluating its effectiveness and potential benefits compared to traditional cardioplegic arrest techniques.MethodsA retrospective analysis was conducted on 168 patients diagnosed with TAAD who underwent surgery at the General Hospital of the Northern Theater Command in China from January 2021 to July 2024. Patients were divided into two groups: early myocardial reperfusion (EMR group, n = 66) and cardioplegic arrest (CA group, n = 102). Perioper

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Negative / Null Result ReportOpen accessNursing

Cultural adaptation and validation of the "Diabetes Quality of Life for Youths" measure of Ingersoll and Marrero into Brazilian culture Adaptación cultural y validación para la cultura brasileña del instrumento "Diabetes Quality of Life for Youths" de Ingersoll y Marrero Adaptação cultural e validação da medida "Diabetes Quality of Life for Youths" de Ingersoll e Marrero para a cultura brasileira

Tatiana de Sá Novato, Sonia Aurora Alves Grossi, Miako Kimura · 2008 · Revista Latino-Americana de Enfermagem

The aim of this study was to adapt the "Diabetes Quality of Life for Youths (DQOLY)" measure into Brazilian culture and to analyze its psychometric properties. The cross-cultural adaptation included the phases of translation, backtranslation, committee review, and pretesting. The adapted instrument was applied to 124 type 1 diabetes mellitus´adolescents. The reliability results showed adequate Cronbach's alpha coefficients (0.8695 for Satisfaction domain, 0.8658 for Impact, 0.8387 for Worries and 0.9333 for total), with the exclusion of 3 inconsistent items. The test-retests showed no si

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Negative / Null Result ReportOpen accessMedicine

Duration of Untreated Psychosis in Chinese and Mauritian: Impact of Clinical Characteristics and Patients' and Families' Perspectives on Psychosis.

Jaya Prishni Devi Thakoor, Huixi Dong, Xiaojie Zhang et al. · 2016 · PLoS ONE

Background Duration of untreated psychosis (DUP) is a potentially modifiable prognostic factor of course and prognosis of psychiatric disorders. Few studies have demonstrated that different cultural backgrounds or perspectives on psychosis may be important factors to the DUP. This study attempted to explore whether the DUP was different in Chinese and Mauritians and to clarify potential influencing factors to a long DUP (>3 months). Methods 200 patients from China and 100 patients from Mauritius were enrolled in the study. Their respective family members were also recruited. Demographic and cl

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Negative / Null Result ReportOpen accessBusiness

The Effect of Corporate Governance on Firms’ Capital Structure of Listed Companies in Sri Lanka

Bulathsinhalage Siromi, Pathirawasam Chandrapala · 2017 · Journal of Competitiveness

There is a great awareness among the researchers to carry out researches on corporate governance and it contributes to the firms’ competitive advantage and business success. In today’s turbulent economic environment, competitiveness has become more important than ever for a firm’s survival and success. However, there is a gap in studies focusing on corporate governance and capital structure in the context of Sri Lanka. The aim of this study is to empirically investigate whether attributes of corporate governance affect decisions on capital structure of listed companies in Sri Lanka. The sample

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Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry

Social Anxiety Symptoms in The Visually Impaired Versus Healthy Control: Saudi Arabian Samples

Alsubaie SS · 2025 · Neuropsychiatric Disease and Treatment

Sultan Saad Alsubaie Department of Psychiatry, Armed Forces Hospital, Khamis Mushayt, Saudi ArabiaCorrespondence: Sultan Saad Alsubaie, Consultant Psychiatrist, psychiatry department, Armed Forces Hospital Southern Region, P.O. Box 101, Khamis Mushayt, Saudi Arabia, Tel +96-6503799971, Email dr.slt4444@gmail.comPurpose: This study aims to compare self-esteem and social anxiety disorder (SAD) symptoms levels between visually impaired and sighted individuals, and to explore the relationship between social anxiety and various sociodemographic factors.Materials and Methods: A case-control study wa

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Negative / Null Result ReportOpen accessAnimal culture

How safe is the use of chlorpyrifos: Revelations through its effect on layer birds

P. P. Singh, Ashok Kumar, R. S. Chauhan et al. · 2016 · Veterinary World

Aim: The present study was aimed to investigate the immunological competence of chlorpyrifos (CPF) insecticide after oral administration in layer chickens. Materials and Methods: A total of 20 White Leghorn birds were given CPF in drinking water at 0.3 ppm/bird/day (no observable effect level dose) for a period of 3-month. Immune competence status of layer birds and chicks hatched from CPF-treated birds were estimated at 15 days interval in layer birds and monthly interval in chicks using immunological and biochemical parameters. Results: There was a significant decrease in values of total leu

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Negative / Null Result ReportOpen accessSurgery

Comprehensiveness of online sources for patient education on otosclerosis

Ahmet Adnan Cırık, Yeşim Esen Yiğit, Ahmet Mahmut Tekin et al. · 2024 · Frontiers in Surgery

PurposeThis study aimed to assess the readability indices of websites including educational materials on otosclerosis.MethodsWe performed a Google search on 19 April 2023 using the term “otosclerosis.” The first 50 hits were collected and analyzed. The websites were categorized into two groups: websites for health professionals and general websites for patients. Readability indices were calculated using the website https://www.webfx.com/tools/read-able/.ResultsA total of 33 websites were eligible and analyzed (20 health professional-oriented and 13 patient-oriented websites). When patient-orie

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Negative / Null Result ReportOpen accessMedicine

Effects of Intraosseous Tibial vs. Intravenous Vasopressin in a Hypovolemic Cardiac Arrest Model

Justin Fulkerson, MSN, Robert Lowe, BSN, Tristan Anderson, BSN et al. · 2016 · Western Journal of Emergency Medicine

Introduction: This study compared the effects of vasopressin via tibial intraosseous (IO) and intravenous (IV) routes on maximum plasma concentration (Cmax), the time to maximum concentration (Tmax), return of spontaneous circulation (ROSC), and time to ROSC in a hypovolemic cardiac arrest model. Methods: This study was a randomized prospective, between-subjects experimental design. A computer program randomly assigned 28 Yorkshire swine to one of four groups: IV (n=7), IO tibia (n=7), cardiopulmonary resuscitation (CPR) + defibrillation (n=7), and a control group that received just CPR (n=7).

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Negative / Null Result ReportOpen accessMedicine (General)

Evaluation of Fusiform-Shaped Stents for Wide-Neck Intracranial Aneurysm Treatment

Zhen Yu Jia, Yuan Yuan Jiang, Jung Min Woo et al. · 2018 · Neurointervention

Purpose Wide-neck aneurysms (WNAs) associated with a dilated parent artery (PA) are not uncommon morphological abnormalities and usually cause inappropriate wall apposition and incomplete neck coverage of a tubular stent in stent-assisted coiling of aneurysms. We aimed to introduce a fusiform-shaped stent (FSS) and test its effectiveness in treating intracranial WNAs associated with a dilated PA using a three-dimensional (3D) model. Materials and Methods Two FSS types were designed with the middle one-third segment dilated by 10% (FSS10) and 20% (FSS20) and were compared with the tubular-shape

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Negative / Null Result ReportOpen accessPublic aspects of medicine

General self-efficacy and hypertension treatment adherence in Algerian private clinical settings

Said Kara · 2022 · Journal of Public Health in Africa

Background. The purpose of this study was to investigate the connection between self-efficacy and treatment adherence, working on the assumption that self-efficacy plays a role in determining treatment adherence in chronic diseases. Hypertension affects one-third of the world’s population. In Africa, hypertension is a leading cause of death from a non-communicable disease. Modifications to lifestyle and behavior, as well as increased access to pharmaceuticals, are necessary for every African nation to bring the prevalence of hypertension and cardiovascular disorders under control. Methods. In

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Negative / Null Result ReportOpen accessInternal medicine

Association analysis of a highly polymorphic CAG Repeat in the human potassium channel gene KCNN3 and migraine susceptibility

Ovcaric Mick, Lea Rod, Sundholm James et al. · 2005 · BMC Medical Genetics

Abstract Background Migraine is a polygenic multifactorial disease, possessing environmental and genetic causative factors with multiple involved genes. Mutations in various ion channel genes are responsible for a number of neurological disorders. KCNN3 is a neuronal small conductance calcium-activated potassium channel gene that contains two polyglutamine tracts, encoded by polymorphic CAG repeats in the gene. This gene plays a critical role in determining the firing pattern of neurons and acts to regulate intracellular calcium channels. Methods The present association study tested whether le

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Negative / Null Result ReportOpen accessDentistry

Comparison of Shear Bond Strengths of Orthodontic Brackets Bonded with Three Different Curing Techniques

Hakan Türkkahraman, Cenker Küçükeşmen · 2005 · Turkish Journal of Orthodontics

The aim of our study was to compare shear bond strengths of orthodontic brackets bonded with chemically cured, halogen light cured and LED cured adhesive systems. 45 extracted human premolar teeth were randomly divided into 3 groups. Bicuspid metal brackets were bonded on first group of teeth with chemically cured bonding system (Rely-a-Bond). Second group were bonded with halogen light cured bonding system (Light Bond). Last group were bonded with LED light cured bonding system (Light Bond). Each specimen was then loaded to universal testing machine. Bond strength was determined in the shear

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Negative / Null Result ReportOpen accessOrthopedic surgery

Infection Rates in Open Fractures of the Tibia: Is the 6-Hour Rule Fact or Fiction?

Ameya S. Kamat · 2011 · Advances in Orthopedics

Aims. Emergency debridement has long been the standard of care for open fractures of the tibia as infection is an important complication. The timing of operative debridement can be debated. We review open fractures of the tibia and compare infection rates in those that were operated on within and after 6-hours. Method. 103 consecutive open fractures of the tibia were reviewed. The data was analysed retrospectively with regard to severity of fracture and incidence of infection. Infection rates over a three-month period were compared between the two groups. Results. 12 (11.6%) patients developed

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Negative / Null Result ReportOpen accessMedicine

Comparison of Characteristics According to Reflux Type in Patients With Laryngopharyngeal Reflux

Jun Seok Lee, Ah Ra Jung, Jung Min Park et al. · 2018 · Clinical and Experimental Otorhinolaryngology

Objectives To analyze laryngopharyngeal reflux (LPR) as an acidic, nonacidic, or mixed type according to 24-hour multi-channel intraluminal impedance (MII) pH monitoring and the clinical characteristics of each type. Methods Ninety patients were prospectively enrolled in this study. All patients underwent 24-hour MII pH monitoring as a diagnostic tool. Eighty-three patients were diagnosed with LPR. The patients were classified into three groups according to the pH of the hypopharyngeal probe: the acid reflux group, nonacid reflux group, and mixed reflux group. Subjective symptoms and objective

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Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine

Safety and efficacy of self-expandable metallic stent combined with 125I brachytherapy for the treatment of malignant obstructive jaundice

Ye Sheng, Xiaobo Fu, Guobao Wang et al. · 2023 · Cancer Imaging

Abstract Background Several previous studies demonstrated that the combination of self-expandable metallic stents (SEMS) and 125I seed implantation might prolong stent patency and obtain survival benefits for malignant obstructive jaundice (MOJ) patients. However, these studies rarely mentioned a comparison between CT-guided intratumoral 125I seed implantation and intraluminal 125I seed strand insertion combined with stenting for the management of MOJ. This study aimed to further evaluate the safety and efficacy of SEMS combined with 125I brachytherapy in the management of unresectable MOJ. Me

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Negative / Null Result ReportOpen accessBiochemistry

Effect of carbamazepine and levetiracetam on coagulation parameters: Prothrombin time, activated partial thromboplastin time, D-dimer, and fibrinogen levels

Li Jiaohui, Zhong Chengyun, Bian Guanji · 2025 · Journal of Medical Biochemistry

Background: Epilepsy is a prevalent neurological disorder, and evaluating its treatment strategies is highly significant. This study aimed to compare the effects of monotherapy with carbamazepine and levetiracetam on the results of coagulation tests, including prothrombin time, activated partial thromboplastin time, fibrinogen, and D-dimer levels, as well as on seizure control in patients with partial-onset epilepsy. Methods: A total of 89 patients diagnosed with POE and treated at our hospital between January 2023 and January 2024 were enrolled. The patients were divided into the carbamazepin

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Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology

Effect of an Oral Adsorbent, AST-120, on Dialysis Initiation and Survival in Patients with Chronic Kidney Disease

Shingo Hatakeyama, Hayato Yamamoto, Akiko Okamoto et al. · 2012 · International Journal of Nephrology

The oral adsorbent AST-120 has the potential to delay dialysis initiation and improve survival of patients on dialysis. We evaluated the effect of AST-120 on dialysis initiation and its potential to improve survival in patients with chronic kidney disease. The present retrospective pair-matched study included 560 patients, grouped according to whether or not they received AST-120 before dialysis (AST-120 and non-AST-120 groups). The cumulative dialysis initiation free rate and survival rate were compared by the Kaplan-Meier method. Multivariate analysis was used to determine the impact of AST-

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Negative / Null Result ReportOpen accessScience (General)

Excessive bowel volume loss during anus-preserving surgery for rectal cancer affects the bowel function after operation: A prospective observational cohort study (Bas-1611)

Fan Liu, Peng Guo, Quan Wang et al. · 2023 · Heliyon

Background: Bowel volume loss during anus-preserving surgery (APS) may result in low anterior resection syndrome (LARS). We conducted this prospective observational cohort study to measure the incidence of LARS after surgery and evaluate the relationship between bowel volume loss and bowel function. Methods: Patients with R0 resectable rectal cancer who consented to several bowel function surveys through telephone interviews after the operation were included. Enrolled patients underwent standard APS for rectal cancer, and three length indexes, viz. length of excised bowel, length of the distal

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Negative / Null Result ReportOpen accessMedicine

Comparison of Mobilisation with Movement and Cryotherapy in Shoulder Impingement Syndrome-A Randomised Clinical Trial

Saumya Srivastava, Charu Eapen, Harramb Mittal · 2018 · Journal of Clinical and Diagnostic Research

Introduction: Shoulder Impingement Syndrome (SIS) is one of the common cause of shoulder ailment which leads to pain and restriction of the movements. Though Mobilisation with Movement and cryotherapy, both are found to be effective in managing SIS, there is no comparison done between the two treatments. Aim: To compare the effectiveness of Mobilisation With Movement (MWM) and cryotherapy in SIS. Materials and Methods: A randomised clinical trial was conducted on 22 subjects who aged between 18-64 years, and those who had a positive painful arc, three positive tests out of five i.e., Neer’s Im

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Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system

Comparison of 15–20 mmHg versus 20–30 mmHg Compression Stockings in Reducing Occupational Oedema in Standing and Seated Healthy Individuals

Cleusa Ema Quilici Belczak, José Maria Pereira de Godoy, Amélia Cristina Seidel et al. · 2018 · International Journal of Vascular Medicine

Background. Elastic compression stockings (ECS) are effective in preventing and reducing occupational edema (OE), but the optimal pressure according to the prevalent working position during the day is still controversial. Objective. To compare the effectiveness of ECS with different pressures (15–20 mmHg or 20–30 mmHg) for reducing OE in individuals working in different prolonged postures. Methods. This cross-sectional study comprised 116 lower limbs of 58 individuals divided into three groups according to their prevalent postures over the day (sitting, standing, or combination). Volumetric me

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