Effect of an Oral Adsorbent, AST-120, on Dialysis Initiation and Survival in Patients with Chronic Kidney Disease
Shingo Hatakeyama; Hayato Yamamoto; Akiko Okamoto; Kengo Imanishi; Noriko Tokui; Teppei Okamoto; Yuichiro Suzuki; Naoaki Sugiyama · 2012 · International Journal of Nephrology
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The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
The oral adsorbent AST-120 has the potential to delay dialysis initiation and improve survival of patients on dialysis. We evaluated the effect of AST-120 on dialysis initiation and its potential to improve survival in patients with chronic kidney disease. The present retrospective pair-matched study included 560 patients, grouped according to whether or not they received AST-120 before dialysis (AST-120 and non-AST-120 groups). The cumulative dialysis initiation free rate and survival rate were compared by the Kaplan-Meier method. Multivariate analysis was used to determine the impact of AST-
Abstract by Shingo Hatakeyama; Hayato Yamamoto; Akiko Okamoto; Kengo Imanishi; Noriko Tokui; Teppei Okamoto; Yuichiro Suzuki; Naoaki Sugiyama, International Journal of Nephrology (2012) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1155/2012/376128