21,742 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
He C, Gu X, Liu Y et al. · 2026 · Frontiers in cellular and infection microbiology
Objective This study aims to investigate the impact of mutations within the major hydrophilic region (MHR) of the hepatitis B virus (HBV) S gene on the expression, secretion, and antigenicity of hepatitis B surface antigen (HBsAg), and…
View details →Jimenez CM, Kreizinger Z, Gyuranecz M et al. · 2026 · Poultry science
The control and prevention of Mycoplasma (M.) synoviae infections have been significantly improved by the use of the MS-H live vaccine strain. This vaccine has been used globally for decades; therefore, many technical approaches have been…
View details →Zhang H, Wu W, Xu J · 2026 · Frontiers in oncology
Early ampullary tumors are challenging to diagnose due to their complex surrounding structures and deep anatomical location. We report a rare case in which enhanced computed tomography (CT), magnetic resonance imaging (MRI), magnetic…
View details →Busi R, Machingal P, Hemachandra N et al. · 2025 · Preprint
The size of the protein sequence database is increasing without a consequent increase in the number of proteins with known molecular function, especially at the fine-grained level. Alignment-based approaches such as BLAST and profile…
View details →Sato T, Nishitsuka K, Itoh T et al. · 2025 · Preprint
Deep learning has shown promise in diabetic retinopathy screening using fundus images. However, many existing models operate as “black boxes,” providing limited interpretability at the lesion level. This study aimed to develop an…
View details →T JS, Chetty N · 2025 · Preprint
Abstract Wind speed distribution modelling serves as an essential tool to assess wind energy resources while identifying optimal wind turbine locations. Three statistical models, including Bimodal Mixture Weibull (BMW), Modified Bimodal…
View details →An SY, Kim I, Hong SH et al. · 2026 · Protein science : a publication of the Protein Society
Anti-CRISPR (Acr) proteins are phage-encoded anti-defense factors that suppress CRISPR-Cas immunity in bacteria. AcrIIA8 was previously identified as an inhibitor of Streptococcus pyogenes Cas9 (SpyCas9) through functional assays of…
View details →Nie YH, Li Q, Lu YJ et al. · 2026 · Protein expression and purification
C14orf119 is a functionally uncharacterized mitochondrial protein potentially implicated in ischemic stroke pathogenesis. To enable comprehensive biological studies, we developed and validated a specific polyclonal antibody against this…
View details →Hilgendorf J, Calisto V, Cardoso DN et al. · 2025 · Environmental toxicology and pharmacology
Sediments play a key role in chemical partitioning in aquatic ecosystems, acting as sinks for lipophilic and persistent compounds. However, sediment hazard assessment is limited, often underestimating risks by focusing on short-term,…
View details →Ito T, Yoshie T, Yoshimura S et al. · 2025 · Studies in health technology and informatics
In this study, we combined automatically generated labels from large language models (LLMs) with a small number of manual annotations to classify adverse event-related treatment discontinuations in Japanese EHRs. By fine-tuning JMedRoBERTa…
View details →Das D, Chawla B, Lomi N et al. · 2025 · Cureus
Introduction Artificial intelligence (AI) is increasingly being integrated into ophthalmic diagnostics, offering potential for efficient screening of common retinal diseases. The Medios AI system by Remidio (Singapore, Singapore), designed…
View details →Qiu W, Yan YK, Kang JP et al. · 2025 · Clinical laboratory
Background Nucleated red blood cells (NRBCs) play a crucial role in automated blood analysis, particularly in the diagnosis and monitoring of blood disorders. This study examines the limitations of the Sysmex XN-9000 fully automated…
View details →Salahat D, Mujahed R, Jaber M et al. · 2026 · Oxford medical case reports
Tuberous Sclerosis Complex (TSC) is a rare genetic disorder characterized by the development of benign tumors in multiple organs. This report presents an unusual case of early-onset renal cystic disease in a 1-year-old male with TSC,…
View details →Saad F, Shams S, Ayaz S et al. · 2025 · Journal of medical virology
Cytomegalovirus (CMV) poses significant risks to infants and immunocompromised individuals. This study investigated the prevalence, associated risk factors, and phylogenetic profile of CMV DNA in the breast milk of lactating mothers in…
View details →Ueda M, Mitani H, Nakaki Y et al. · 2025 · Interventional radiology (Higashimatsuyama-shi (Japan)
Purpose: To evaluate the performance of automated tumor-feeder detection software in transarterial chemoembolization for hepatocellular carcinoma using angio-computed tomography. Material and Methods: This was a retrospective study of 107…
View details →Cui N, van Beers RJ, Smeets JBJ et al. · 2025 · Preprint
Emerging evidence suggests that decision making is not a purely cognitive process preceding motor output but rather an embodied phenomenon in which the sensorimotor system actively shapes choice selection. Beta oscillations (13–30 Hz) over…
View details →Mottaghi M, Manda P, Morton EA et al. · 2025 · Cureus
We report the case of a 58-year-old woman who initially presented to the emergency department with intermittent nausea, vomiting, and left upper quadrant abdominal pain for six days. As part of the abdominal pain workup in the emergency…
View details →Smith BJ, Stafne ET, Read QD · 2025 · PhytoFrontiers™
Phytophthora root rot is a major disease of blueberry that relies on cultural practices, including soil amendments, for disease management. We evaluated the effect of three cover crops on the establishment and growth of southern highbush…
View details →Akinosho A, Alexander J, Floyd K et al. · 2025 · Preprint
Transgenerational inheritance of learned behaviors remains a controversial topic in biology. The Murphy lab previously demonstrated that C. elegans exposed to pathogenic Pseudomonas aeruginosa (PA14) not only learn to avoid this bacterium…
View details →Ruiz-Rebollo ML, Muñoz-Moreno MF · 2025 · Medicina clinica
Background Acute pancreatitis can affect elderly people. Conflicting results have been published regarding the role of age in the course of this life-threatening disease. Aim To assess the clinical outcomes of acute pancreatitis in…
View details →Wilmshurst P · 2026 · Clinical medicine (London, England)
One-quarter of adults have a persistent (patent) foramen ovale (PFO). Right-to-left shunting through a PFO can facilitate paradoxical thromboembolism, cryptogenic stroke, paradoxical gas embolism, decompression sickness, arterial…
View details →Wei Q, Wang SA, Garcia-Manero G et al. · 2025 · Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Identification of cytogenetic abnormalities is critical for the classification and risk stratification of myelodysplastic syndromes (MDS). Optical genome mapping (OGM) is an emerging cytogenomic platform that enables high-resolution…
View details →Noorelahi Y · 2025 · Radiology research and practice
Objective Accurate meniscal tear diagnosis is essential for proper knee injury management. While MRI is the gold standard, ultrasound (US) offers a cost-effective alternative. However, its accuracy compared to arthroscopy remains…
View details →Dachraoui K, Ben Osman R, Ben Slama S et al. · 2025 · Vector borne and zoonotic diseases (Larchmont, N.Y.)
A total of 20 horses belonging to the Pasteur Institute of Tunis used for the production of therapeutic serum antiscorpion venom were tested for the presence of antibodies anti-West Nile virus (WNV) during the 2023 outbreak of West Nile…
View details →Nkoy AB, Mumaka FM, Matoka TT et al. · 2026 · Pediatric nephrology (Berlin, Germany)
Background Serum creatinine (SCr), the most used biomarker to evaluate glomerular filtration rate (GFR), might be inaccurate in children with sickle cell anemia (SCA). In this context, cystatin C (SCys) could be of interest. This study…
View details →Hagenbeek A, Masukagami Y, Palanichamy P et al. · 2026 · BMC genomics
The intracellular endosymbiont Candidatus Lariskella (Alphaproteobacteria, Candidatus Midichloriaceae) has been found across a wide diversity of terrestrial arthropods, including ticks, true bugs, beetles, fleas, wasps and moths. Despite…
View details →Wang Y, Kong X, Wei H et al. · 2025 · Haemophilia : the official journal of the World Federation of Hemophilia
Introduction The Bethesda assay (BA) and the Nijmegen-Bethesda assay (NBA) are commonly used to measure inhibitors in patients with haemophilia A (HA). The laboratory results of inhibitor assays have been demonstrated to be highly…
View details →Malinowska K, Wawrzynowicz M, Markowska K et al. · 2025 · Preprint
Conservation decision-making requires accurate identification of causes of population changes. Ecologists often rely on analytical protocols that aggregate high-dimensional monitoring data. We hypothesise that compressing data - either…
View details →Jena S, Kim D, Lee AM et al. · 2025 · Preprint
Abstract Background: Disease heterogeneity across a diverse patient cohort poses challenges to cancer drug development due to inter-patient variability in treatment responses. However, current preclinical models fail to depict…
View details →Caldwell MW, Brownstein CD, Meyer DL et al. · 2025 · Preprint
Accurate reconstruction of the timescale of organismal evolution requires placement of extinct representatives among living branches. In this way, the fossil record has the capacity to revise hypotheses of organismal evolution by producing…
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