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Negative / Null Result ReportOpen accessDermatology

Association Between IFN-γ Gene Polymorphisms and IgA Nephropathy in a Chinese Han Population

Jie Gao; Linting Wei; Xinghan Liu; Li Wang; Dan Niu; Tianbo Jin; Ganglian Yao; Meng Wang · 2017 · Kidney & Blood Pressure Research

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background/Aims: IFN-γ was reported to be involved in the development and progression of Immunoglobulin A nephropathy (IgAN), however, few studies have investigated the association between IFN-γ polymorphisms and IgAN. Therefore, we performed a case-control study to assess the association between IFN-γ polymorphisms and the risk of IgAN. Methods: Sequenom MassARRAY was used to genotype two SNPs (rs1861494 and rs2430561) in 351 patients with IgAN and 310 healthy controls. Associations were evaluated as odd ratios (OR) with 95% confidence intervals (CI). Results: No association was found between

Abstract by Jie Gao; Linting Wei; Xinghan Liu; Li Wang; Dan Niu; Tianbo Jin; Ganglian Yao; Meng Wang, Kidney & Blood Pressure Research (2017) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1159/000473889