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WASTE Journal

Browse the failure-mode index

21,742 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportMedicine

Dung beetles do not profit from enhanced spatial heterogeneity in temperate production forests: A forest manipulation experiment

Asch J, Scherer‐Lorenzen M, Pierick K et al. · 2026 · Journal of Applied Ecology.

Central European forest management strategies promoting structurally homogeneous closed‐canopy forests have led to landscape‐level declines in biodiversity and ecosystem multifunctionality. Conservation‐targeted management programs aim at…

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Negative / Null Result ReportMedicine

Exopolysaccharide biosynthesis and regulation in Leuconostoc mesenteroides influences water holding capacity of fermented plant-based milks.

Sukarno AS, Dong A, Gumulya Y et al. · 2026 · International journal of food microbiology

Physical instability remains a major challenge in fermented plant-based yoghurts in the absence of added texturizing agents. Cultures can improve water holding capacity (WHC) through production of exopolysaccharide (EPS). This study…

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Negative / Null Result ReportMedicine

The influence of adolescent idiopathic scoliosis on hip joint development: a two-year longitudinal evaluation of the hip center-edge angle.

Matsumoto T, Yokoe T, Takahashi T et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

PURPOSE: Several studies have reported an association between adolescent idiopathic scoliosis (AIS) and hip decentration (HD). However, these previous studies evaluated the hip center-edge (CE) angle at only a single time point. This study…

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Negative / Null Result ReportMedicine

Non-modifiable cardiovascular risk factors and coronary plaque characteristics in patients with acute coronary syndromes.

Scalamera R, Covani M, Andreaggi S et al. · 2026 · European heart journal. Cardiovascular Imaging

Aims Cardiovascular risk factors predict adverse clinical outcomes, including acute coronary syndromes (ACS). A recent study showed a close correlation between the number of modifiable risk factors and plaque vulnerability. However, the…

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Negative / Null Result ReportMedicine

Bark beetles as ecosystem engineers: triggered tree mortality rearranges the assemblage of Tree-related Microhabitats in old-growth coniferous forest

Przepióra F, Ciach M · 2025 · Forest Ecology and Management.

Although species with ecosystem engineering capabilities like woodpeckers, ungulates or saproxylic insects may initiate the formation of Tree-related Microhabitats (TreMs), their overall impact on TreM assemblages remains unexplored. Bark…

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Negative / Null Result ReportMedicine

Heat-Killed <i>Enterococcus faecalis</i> EF-2001 Promotes Systemic Th1-Skewed Immune Activation Without Detectable Reduction of Influenza Viral Load in Mice.

Ohashi T, Hagihara M, Asai N et al. · 2026 · Microorganisms

Heat-killed Enterococcus faecalis EF-2001 (EF-2001) is a postbiotic preparation reported to modulate host immunity. However, its specific impact on host immune responses and virological outcomes during the early phase of influenza…

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Negative / Null Result ReportMedicine

Impact of neoadjuvant immunotherapy on postoperative cardiac adverse events in NSCLC: insights from a bidirectional cohort.

Yan C, Zhang X, Hu S et al. · 2026 · International journal of surgery (London, England)

The impact of neoadjuvant chemo-immunotherapy (nCIT) on perioperative cardiac safety in patients undergoing lung cancer resection remains unclear. This study aimed to evaluate the incidence and risk factors of postoperative cardiac adverse…

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Negative / Null Result ReportMedicine

Effect of acute intraperitoneal injection of methylglyoxal on organ injury and oxidative stress in chicks (Gallus gallus domestics).

Okino M, Makino R, Aoki M et al. · 2026 · Comparative biochemistry and physiology. Part A, Molecular & integrative physiology

Methylglyoxal (MGO) is an α-dicarbonyl compound and produced from several metabolic pathways, including glucose metabolism. This compound induces oxidative stress and organ damage in mammals and is associated with various diseases,…

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Negative / Null Result ReportMedicine

Migraine Features and Nociceptive Profile Do Not Influence Conditioned Pain Modulation in Women With Episodic and Chronic Migraine.

de-la-Llave-Rinc&#xf3;n, Ambite-Quesada, Pacho-Hern&#xe1;ndez et al. · 2026 · Pain research & management

To determine the influence of sensitization-associated and neuropathic-like symptoms and clinical features in conditioned pain modulation (CPM) activity in women with episodic or chronic migraine. A cross-sectional study including 70 women…

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Negative / Null Result ReportMedicine

Do the printing orientation angle and layer thickness influence the radiopacity of 3D-printed dental resins?

Yersel, Ucan, Tekce · 2026 · Journal of prosthodontics : official journal of the American College of Prosthodontists

This in vitro study aimed to evaluate the effect of layer thickness, printing orientation angle, and resin type on the radiopacity of 3D-printed dental resins. Three dental 3D-printed resins (VarseoSmile TriniQ, Crowntec, and Primeprint…

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Negative / Null Result ReportOpen accessMedicine

Identifying early changes in imaging, plasma, and digital cognitive biomarkers that correspond to Alzheimer's disease pathology in the presence of autopsy-confirmed co-pathologies.

Chen CD, Aguero C, Melloni A et al. · 2026 · Alzheimer's & dementia : the journal of the Alzheimer's Association

Introduction Alzheimer's disease (AD) biomarkers are assessed on their ability to detect AD pathophysiology in vivo, with confirmation of AD neuropathology only at autopsy. Methods Positron emission tomography (PET), plasma, and cognitive…

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Negative / Null Result ReportMedicine

Expression patterns of risk genes associated with three evolutionarily relevant syndromes in rhesus macaque and human brains.

Karunakaran KB, Purushottam M, Balakrishnan N et al. · 2026 · Translational psychiatry

Depressive disorder (DD), Alzheimer's disease (AD), and schizophrenia (SZ) are evolutionarily relevant traits that disrupt neural networks supporting affect and cognition. While genome-wide association studies have identified risk-related…

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Negative / Null Result ReportMedicine

Quantification of retinal non-perfusion in eyes with diabetic retinopathy to study the association with retinal neovascularisation: INSPIRED study report 3.

Khalid H, Tsai WS, Lamanna F et al. · 2026 · The British journal of ophthalmology

Background/aims To characterise the distribution of retinal non-perfusion and its relationship with neovascularisation elsewhere (NVE) and visual acuity (VA) in referable diabetic retinopathy (DR) using ultra-widefield fluorescein…

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Negative / Null Result ReportMedicine

Measuring Cognitive Flexibility in Chinese Individuals with Obsessive-Compulsive Disorder: Psychometric Validation and Factor Structure of the Chinese Version of the Flexibility in Daily Life Scale.

Yan Z, Chen T, Ma X et al. · 2026 · Psychology research and behavior management

Purpose Impaired cognitive flexibility is a core feature of obsessive-compulsive disorder (OCD) and may contribute to symptom persistence and variabe therapeutic outcomes. However, traditional measures may adequately capture how cognitive…

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Short NoteOpen accessMedicine

Magnetic resonance imaging-induced artefact mimicking torsade de pointes in a patient with an implantable cardiac monitor: a case report.

Toyama Y, Taniguchi Y, Morisue M et al. · 2026 · European heart journal. Case reports

Background Magnetic resonance imaging (MRI) is increasingly performed in patients with cardiac implantable electronic devices. Although generally considered safe under specific protocols, electromagnetic interference may still lead to…

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Methods Dead-EndMedicine

Automation in the IVF laboratory in 2026: four technology domains, an asymmetric evidence base, and the case for parallel development with clinician-side automation.

Dirican EK · 2026 · Journal of assisted reproduction and genetics

Background Operator-dependent laboratory tasks-embryo selection, vitrification and warming, and intracytoplasmic sperm injection (ICSI)-have been the principal targets of IVF laboratory automation, and a fourth strand of work, integrated…

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Negative / Null Result ReportMedicine

Predictable modality transitions and meaningful stimuli facilitate sequential statistical learning between sensory modalities.

Pérez-Bellido A, Duato D, Giannelli F et al. · 2026 · Journal of experimental psychology. Learning, memory, and cognition

Statistical learning is the process of extracting regularities from the environment. Although sequential cross-modal regularities are ubiquitous (e.g., the sight of a falling ball followed by the sound of impact), previous research has…

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Negative / Null Result ReportMedicine

Between hope and uncertainty: the elusive evidence on hyperbaric oxygen therapy and radiotherapy.

Cuccia F, Cracchiolo AN, Piras A et al. · 2026 · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Background Radiotherapy (RT) is a cornerstone in cancer management, but late radiation tissue injury (LRTI) remains a relevant clinical issue, affecting approximately 5% of patients and significantly impacting quality of life. Hyperbaric…

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