Negative / Null Result ReportOpen accessMedicine
Al-Haddad C, Ibrahim H, Salameh N et al. · 2026 · PloS one
Purpose To investigate and compare retinal vascular changes, including superficial macular vessel density, foveal avascular zone, and the macular perfusion densities, in amblyopic, fellow, and control eyes using optical coherence…
View details →Negative / Null Result ReportMedicine
Cerdan-Hernandez E, Palencia-Herranz MJ, Barón M et al. · 2026 · Journal of optometry
Purpose To assess the value of optical coherence tomography angiography (OCTA) peripapillary retinal vascularization in differentiating papilledema from pseudopapilledema. Methods A cross-sectional study, prospective recruitment patients…
View details →Negative / Null Result ReportMedicine
Terzioglu H, Efeoglu S, Sarikaya CH et al. · 2026 · Journal of prosthodontics : official journal of the American College of Prosthodontists
Purpose This study evaluated the effect of periapical X-ray angulation on the diagnostic accuracy of detecting vertical misfits at the implant-abutment interface using Medentika Microcone dental implants (4.0 mm diameter, 11 mm length;…
View details →Negative / Null Result Report
Tu X, Zhuang X, Zhao T et al. · 2026 · Preprint
Abstract Objective: To investigate the effects of intraoperative dexamethasone, furosemide, and their combination on systemic inflammatory response syndrome (SIRS) after endourological lithotripsy for upper urinary tract calculi, and…
View details →Negative / Null Result ReportOpen accessMedicine
Wang X, Xie C, Zheng R et al. · 2026 · Animal microbiome
Termites are a natural component of the diet of Malayan pangolins, whereas artificial diets used under captive conditions may differ substantially from wild prey in structure and composition, particularly in chitin content. This study…
View details →Negative / Null Result ReportOpen accessMedicine
Sayed Ahmad AM, Knikou M · 2026 · Frontiers in neurology
Introduction In this clinical trial, we evaluated changes in the output of motoneurons and spinal inhibitory mechanisms across multiple spinal segments before and after a series of transspinal direct current stimulation (tsDCS) sessions in…
View details →Negative / Null Result ReportOpen accessMedicine
Wrublewsky S, Weigl J, Bickelmann C et al. · 2026 · Journal of functional biomaterials
Surgical sutures are widely used biomaterials in clinical practice. Like all other biomaterials, they induce a foreign body response after implantation that involves inflammation and angiogenesis. Although it is well known that these…
View details →Negative / Null Result ReportOpen accessMedicine
Bagheri Hosseinabadi M, Yu M, Petersen A et al. · 2026 · Annals of work exposures and health
The necessity for respiratory protection has increased due to global threats such as pandemics, industrial accidents, and extreme weather events. The effectiveness of N95 filtering facepiece respirators depends on how well they fit the…
View details →Negative / Null Result ReportMedicine
Pikkujämsä A, Rinne P, Wistbacka JO et al. · 2026 · BMC cardiovascular disorders
Background Long-term survival following off-pump coronary artery bypass grafting (OPCAB) compared with conventional on-pump coronary artery bypass grafting (ONCAB) remains uncertain. Randomised trials and meta-analyses up to 5-10 years…
View details →Negative / Null Result ReportMedicine
Çakır E, Ciğerci Y, Yılmaz S · 2026 · Scientific reports
This study aimed to evaluate the effects of a music intervention on anxiety, pain, and vital signs in patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP). This randomized controlled trial included 70 patients who…
View details →Negative / Null Result ReportMedicine
Schmidt N, Johnson G, Nencka A et al. · 2026 · Studies in health technology and informatics
Although there is variation in clinicians' application of the Rigo classification system (RCS) to adolescent idiopathic scoliosis, no artificial intelligence (AI) models have been developed to standardize the RCS specifically. This study…
View details →Failed Experiment ReportOpen accessMedicine
Lucchetti D, Di Leone A, Sabbatinelli G et al. · 2026 · Frontiers in immunology
Background Triple-negative breast cancer (TNBC) is a heterogeneous disease lacking approved targeted therapies and standardized treatment regimens. Among its molecular subtypes, luminal androgen receptor-positive (LAR+) TNBC is…
View details →Negative / Null Result ReportOpen accessMedicine
Lee SH, Jang JW, Han SH et al. · 2026 · Plants (Basel, Switzerland)
Climate change is intensifying extreme climatic events such as warming and drought. This study investigated the physiological and growth responses of Quercus variabilis , a major broadleaf plantation species in South Korea, to warming and…
View details →Abandoned HypothesisOpen accessMedicine
Holmqvist Larsson K, Falkenström F, Andersson G et al. · 2026 · Child and adolescent psychiatry and mental health
Background Emotion dysregulation is a transdiagnostic construct associated with psychiatric symptomatology. Improving strategies to regulate emotions is an important focus in several psychological treatments. In the current study we…
View details →Negative / Null Result ReportMedicine
Ceylan FA, Tatar Kartaloğlu O, Yılmaz İE · 2026 · Clinical & experimental optometry
Clinical relevance Intraocular lens selection following cataract surgery has implications beyond refractive correction, with different lens chromophore compositions potentially affecting retinal light exposure and downstream visual and…
View details →Abandoned HypothesisOpen accessMedicine
Gerogianni A, Sørensen G, Hoel TN et al. · 2026 · International journal of molecular sciences
Left ventricular assist device (LVAD) implantation is a life-saving therapy for end-stage heart failure but may compromise immune integrity. Mechanical shear stress and surface-induced innate immune activation can trigger bleeding and…
View details →Negative / Null Result ReportMedicine
Chen M, Zhang C, Fan Z et al. · 2026 · BMC musculoskeletal disorders
Background Unicompartmental knee arthroplasty (UKA) has become an effective treatment for medial compartment osteoarthritis of the knee. However, its use in patients who also have patellofemoral joint osteoarthritis (PFOA) before surgery…
View details →Negative / Null Result ReportMedicine
Kragness KA, Trader DJ · 2026 · Chembiochem : a European journal of chemical biology
The proteasome degrades ubiquitinated proteins as well as intrinsically disordered proteins that can be processed independently of ubiquitin signaling. The 20S core particle (CP) plays a key role in the degradation of unstructured…
View details →Negative / Null Result ReportOpen accessMedicine
Salama AM, Al-Obeed RS, Helmy A et al. · 2026 · Frontiers in plant science
This study evaluated the combined effects of grafting and deficit irrigation (DI) on soil attributes, vegetative growth, yield components, fruit quality, and water productivity of 'Crimson Seedless' grapevines under semiarid conditions. It…
View details →Negative / Null Result ReportOpen accessMedicine
Glienke L, Hall TL, Ghani KR et al. · 2026 · Urolithiasis
Control of fragment size during laser lithotripsy has taken on increasing importance with adoption of ureteroscopic aspiration technologies. The objective of this study was to characterize the relationship between laser-fiber-to-stone…
View details →Negative / Null Result ReportMedicine
Won JH, Shin JW, Kwon J et al. · 2026 · Journal of orthopaedic surgery and research
Purpose To determine whether ulnar positive variance (UPV) and relative ulnar positive variance (RUPV) affect clinical outcomes following arthroscopic transosseous repair of triangular fibrocartilage complex (TFCC) foveal tears. Methods…
View details →Negative / Null Result ReportMedicine
Diken Türksayar AA, Öztemel N, Yeşil Kurt İB et al. · 2026 · Odontology
This study evaluated the shear bond strength (SBS) of two dual-cure resin cements to a stereolithography-fabricated 3D-printed permanent crown material after various surface pretreatment protocols. Disc-shaped specimens were fabricated…
View details →Negative / Null Result ReportMedicine
Ma Z, Luan H, Abulimiti K et al. · 2026 · BMC surgery
Objective To compare the clinical and radiographic outcomes of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of double-level lumbar spondylolisthesis combined with spinal…
View details →Negative / Null Result ReportMedicine
Liu X, Zhao J, Wu Y et al. · 2026 · Scientific reports
Swallowing and diaphragmatic functions share neural regulatory pathways and require synchronous assessment. Patients who have had a stroke are susceptible to many complications, of which dysphagia and diaphragmatic dysfunction are…
View details →Negative / Null Result ReportMedicine
Sullivan M, Perea LL, Bradburn E et al. · 2026 · Journal of orthopaedic trauma
Objectives To evaluate whether preoperative intravenous tranexamic acid (TXA) reduces postoperative blood transfusion rates in geriatric patients undergoing operative treatment for hip fracture. Methods Design Prospective, double-blinded,…
View details →Negative / Null Result ReportOpen accessMedicine
Zhang Z, Liu Y, Yang H et al. · 2026 · Frontiers in cellular neuroscience
Purpose To compare the clinical efficacy of endoscopic (ECTR) and open (OCTR) carpal tunnel release for carpal tunnel syndrome (CTS) and provide evidence-based surgical guidance. Methods A retrospective cohort study was conducted including…
View details →Negative / Null Result ReportOpen accessMedicine
Ramos-Ramos V, Dextre-Herrera S, Ramírez-Vargas G et al. · 2026 · Journal of clinical and experimental dentistry
Background Silane is used as a coupling agent on glass fiber posts to enhance chemical interaction at the post-resin cement interface. This in vitro study evaluated the bond strength of silane-treated glass fiber posts at different solvent…
View details →Negative / Null Result ReportOpen accessMedicine
Hassania Y, Hassanpour S, Zendehdel M et al. · 2026 · Poultry science
This study aimed to detemine association of central α-klotho with dopaminergic and melanocortin receptors on feed intake regulation in chicken. 264 meat-type chicken were included 6 experiments, each containing 4 groups. In experiment 1,…
View details →Negative / Null Result ReportOpen accessMedicine
Tez Yaşar BÇ, Çakmak AB, Eberliköse H et al. · 2026 · Children (Basel, Switzerland)
Background/objectives Early childhood caries (ECC) is a chronic inflammatory condition that may impose a systemic burden in pediatric patients. This study aimed to evaluate the association between dental caries severity, classified by dmft…
View details →Negative / Null Result ReportMedicine
Kużdżał A, Gambuś K, Moszczyński K et al. · 2026 · Advances in clinical and experimental medicine : official organ Wroclaw Medical University
Background Positron emission tomography (PET) using 18-fluorodeoxyglucose (18-FDG) is the primary imaging modality for mediastinal staging of lung cancer. Higher standardized uptake value (SUVmax) reportedly correlates with more aggressive…
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