21,309 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Heidari N, Maroufi A, Shams-Alizadeh N · 2026 · Clinical neuropharmacology
Objective Neuroinflammation, reflected in hematological and inflammatory biomarkers, plays a role in bipolar disorder. Electroconvulsive therapy (ECT) is effective for treatment-resistant bipolar disorder, but its impact on these…
View details →Sweeney L, Schapira L, Webster S et al. · 2026 · Pain
Abstract Chronic cancer-related pain affects up to 40% of cancer survivors, yet why pain persists after cancer treatment has ended is not well-understood. The Cancer Threat Interpretation (CTI) model proposes that fear of cancer recurrence…
View details →Kikut-Stein A, Jesch E, Dhawan D et al. · 2026 · Journal of health communication
In the wake of the COVID-19 pandemic, a critical question for health communication is whether misinformation exposure and misperceptions about one health topic have far-reaching, or "spillover," effects on health behavior in general. The…
View details →Fasting A, Simensen MV, Sele P et al. · 2026 · Journal of affective disorders
Background This retrospective quality-control study examined whether patients with posttraumatic stress disorder (PTSD) at a specialized Norwegian inpatient hospital exhibited high levels of interpersonal problems before treatment and…
View details →Raha SJ, Bhatia P, Bansal D et al. · 2026 · Cancer chemotherapy and pharmacology
Background High‑dose methotrexate (HD‑MTX) is a cornerstone of pediatric acute lymphoblastic leukaemia (ALL) therapy. However, deviations from protocol-mandated infusion durations need regular monitoring as part of standard quality care.…
View details →Hunter M, Skippen P, Templio SL et al. · 2026 · Cognitive, affective & behavioral neuroscience
Risk-taking in young people is often attributed to a mismatch between slowly maturing cognitive control networks and overactive reward networks, leading to impulsive actions. However, evidence is inconsistent, and these models do not…
View details →Pizzi A, Cotrufo PP, Farinaro G et al. · 2026 · Stereotactic and functional neurosurgery
Introduction Gamma knife radiosurgery (GKRS) is an established effective treatment for medically intractable trigeminal neuralgia (TN), but outcome predictors remain controversial. Notably, the influence of neurovascular conflict (NVC)…
View details →Lustermans H, Bruinhof N, Beijers R et al. · 2026 · Appetite
During the perinatal period, mental health issues and poor diet quality can adversely affect maternal and infant outcomes. Previous studies described associations between perinatal mental health and diet quality, but the direction of these…
View details →Peterson R, Paitan SC, Belitsos OA et al. · 2026 · Experimental and clinical psychopharmacology
Alcohol use is common among college students and often linked to negative consequences. Protective behavioral strategies (PBS) can reduce alcohol use and related harms. This study examined whether dating/sexual PBS provide unique…
View details →Axelsen JK, Boesen L, Bisbjerg R et al. · 2026 · Scandinavian journal of urology
Objective To compare adjustable continence balloons (ProACT) implanted above the pelvic floor with or without subsequent placement of a third balloon (AP) with a modified technique placing balloons below the pelvic floor (BP). Materials…
View details →Koch M, Mostert J, Strijbis EM et al. · 2026 · Journal of neurology, neurosurgery, and psychiatry
Background Phase 2 clinical trials in primary progressive multiple sclerosis (PPMS) often use MRI brain volume measures as their primary endpoint. Here, we investigate the longitudinal association between change in MRI outcomes and change…
View details →Lee SJ, Han HH, Eom JS et al. · 2026 · Plastic and reconstructive surgery
Background The deep inferior epigastric perforator (DIEP) flap is widely used in autologous breast reconstruction, with its success heavily reliant on the vascular anatomy, particularly midline crossing-over vessels that facilitate…
View details →Raudeberg R, Iverson GL · 2026 · Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists
Objective The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) is a brief neuropsychological screening battery that measures aspects of attention, immediate and delayed memory, and verbal and…
View details →Hems T · 2026 · The Journal of hand surgery, European volume
There is significant interest in research on the pathology, natural history and treatment of brachial plexus birth injury. This article comments on a few newly published papers in the Journal of Hand Surgery (European Volume) to highlight…
View details →Takenaka K, Kawamoto A, Hibiya S et al. · 2026 · Inflammatory bowel diseases
Background and aims Clinicians need data on the responsiveness of ileal strictures of Crohn's disease (CD) to biologic therapy, yet most trials prioritize mucosal healing. We quantified short‑term changes in ileal strictures under biologic…
View details →Kongsnes BEB, Asprusten TT, Wyller VBB et al. · 2026 · Stress (Amsterdam, Netherlands)
Chronic fatigue after Epstein-Barr virus (EBV) infection is a significant health problem among adolescents, yet its underlying mechanisms remain unclear. This study investigated whether preinfection hair cortisol levels predict chronic…
View details →Luppino-Assad AP, Mello RP, Medeiros-Ribeiro AC et al. · 2026 · Rheumatology (Oxford, England)
Objectives To evaluate humoral immune response to recombinant zoster vaccine (RZV) in immunosuppressed patients with SSc compared with healthy controls, to identify factors influencing vaccine response and to assess RZV safety and impact…
View details →Kıraç FÇ, Özen MY, Kıraç R et al. · 2026 · Geriatric nursing (New York, N.Y.)
Objectives This study aims to examine the effect of self-efficacy in chronic disease management on engagement in healthy aging and life satisfaction in individuals with diabetes. Methods This cross-sectional, quantitative study utilized…
View details →Freeman D, Rosebrock L, Waite F · 2026 · Schizophrenia research
Background Initial patient perceptions of a treatment's credibility, and expectations for improvement, have been shown to predict to a small degree outcomes for common mental health disorders. This study aimed to discover: how patients…
View details →Sawyer Z, Sorial M, Liauw JC · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
IntroductionImmune checkpoint inhibitors have improved outcomes for solid tumors but are associated with immune-related adverse events (irAEs). Literature suggests that patients with an absolute lymphocyte count (ALC) ≥ 2000 cells/mm3…
View details →Chernetska V, Millgram Y · 2025 · Preprint
Background: Suicidal thoughts affect approximately 10% of the population during their lifetime. In about one-third of cases, these thoughts persist, contributing to poorer health and elevated suicide risk. Emotion regulation deficits were…
View details →Yakubu YH, Saani MM · 2026 · Nursing open
Aim To evaluate the effect of a structured training intervention on ICU nurses' knowledge-based competence in VAP prevention in a resource-limited setting and identify personal, environmental and organisational barriers to implementation.…
View details →Kumar N, Gomes PL, Jett S et al. · 2025 · Laryngoscope investigative otolaryngology
Objectives Saddle nose deformity (SND) can be associated with nasal septal perforation (NSP). Both SND and NSP are observed in granulomatosis with polyangiitis (GPA) patients. This study aimed to compare the prevalence and severity of SND…
View details →Martinez Paulino A, Arias Diaz DJ, King M et al. · 2026 · ACR open rheumatology
Objective To examine whether group-based medical mistrust predicts willingness to enroll in a rheumatology clinical trial and, among those unwilling, to identify logistical factors that most influence their decision. Methods We conducted a…
View details →Munns A, Feron J, Duda J et al. · 2026 · Preprint
Purpose:Motivation and self-efficacy are established predictors of engagement and persistence within structured exercise programmes; however, it remains unclear whether these psychological factors predict objective adherence metrics and…
View details →Beaugard CA, Khan S, Oblath R et al. · 2026 · Journal of dual diagnosis
Objective Psychiatric and substance use disorders commonly co-occur, yet treatment is often siloed. To improve treatment utilization for individuals with co-occurring disorders in the psychiatric setting it important to understand current…
View details →Aoki A, Koresawa K, No Y et al. · 2026 · Clinical biomechanics (Bristol, Avon)
Background To prospectively examine how lower extremity movement patterns during single-leg landings predict anterior cruciate ligament (ACL) injuries in adolescent Japanese basketball players during a 3-year follow-up period. Methods 44…
View details →Hart SN, Bergamaschi TS · 2025 · Preprint
Objective To develop and validate an agent-based Large Language Model (LLM) system for extracting structured data from breast cancer synoptic pathology reports and assess the performance gap between synthetic and real-world validation.…
View details →Chira A, de la Fuente Garcia S · 2025 · Preprint
Morality is deeply rooted in the context of relationships. Yet the influence of relational factors, such as attachment, on moral concerns remains largely unexplored. Nonetheless, recent scholarship has shed some light on the connection…
View details →Sharpe L, Shaw J, Boyse JB et al. · 2026 · British journal of health psychology
Aims Asthma is a chronic condition characterized by episodes of breathlessness. Although common, asthma is known to be associated with higher rates of depression and anxiety, but there are few studies that have attempted to document the…
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