Biosafety of a 3D-printed intraocular lens made of a poly(acrylamide-co-sodium acrylate) hydrogel in vitro and in vivo
Jia-Wen Li; Yi-Jian Li; Xi-Su Hu; Yu Gong; Ben-Bin Xu; Hai-Wei Xu; Zheng-Qin Yin · 2020 · International Journal of Ophthalmology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
AIM: To assess the biosafety of a poly(acrylamide-co-sodium acrylate) hydrogel (PAH) as a 3D-printed intraocular lens (IOL) material. METHODS: The biosafety of PAH was first evaluated in vitro using human lens epithelial cells (LECs) and the ARPE19 cell line, and a cell counting kit-8 (CCK-8) assay was performed to investigate alterations in cell proliferation. A thin film of PAH and a conventional IOL were intraocularly implanted into the eyes of New Zealand white rabbits respectively, and a sham surgery served as control group. The anterior segment photographs, intraocular pressure (IOP), bl
Abstract by Jia-Wen Li; Yi-Jian Li; Xi-Su Hu; Yu Gong; Ben-Bin Xu; Hai-Wei Xu; Zheng-Qin Yin, International Journal of Ophthalmology (2020) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.18240/ijo.2020.10.03