Negative / Null Result ReportMedicine
Su J, Zhang WB, Sun B et al. · 2025 · Experimental & applied acarology
Haemaphysalis flava Neumann, 1897 is recognized as a vector for Dabie bandavirus (severe fever with thrombocytopenia syndrome virus, SFTSV), which is the etiological agent of severe fever with thrombocytopenia syndrome (SFTS). The tick…
View details →Negative / Null Result ReportOpen accessMedicine
Edsor E, Jose M, Sajesh S et al. · 2025 · Journal of pharmacy & bioallied sciences
Background The aim of this study is to assess whether there is a difference in the wound healing process following the extraction of a tooth between type 2 diabetes patients on oral hypoglycemic medications and nondiabetic patients.…
View details →Failed Experiment ReportMedicine
Del Rivero J, Donahue RN, Marte JL et al. · 2025 · The oncologist
Background It has been hypothesized that sequencing antigen-directed immunotherapy with immune checkpoint inhibitors could prime a tumor for immune response to immune checkpoint inhibitors. Methods This study (NCT03072160) was designed to…
View details →Failed Experiment ReportMedicine
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of dairy science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
View details →Negative / Null Result Report
Rezazadeh F, Lavaee F, Dezhkameh S et al. · 2025 · Preprint
Abstract Background: Lichen planus (LP), an inflammatory and chronic disorder, is immune-mediated and influences nails, skin, hair, and mucosal tissues. Autoimmune diseases affect females more commonly, and it is reported that there is an…
View details →Negative / Null Result Report
So R, Kariyama K, Oyamada S et al. · 2024 · Preprint
Objective To evaluate the effectiveness of screening and ultra-brief intervention (Ultra-BI) delivered by primary care physicians in less than 1 minute compared to simplified assessment only (SAO) for reducing alcohol consumption among…
View details →Negative / Null Result ReportOpen accessMedicine
Oliveira AHA, Paula DM, Serafini S et al. · 2026 · Acta cirurgica brasileira
Purpose To evaluate the effects of direct and remote ischemic preconditioning and postconditioning on kidney ischemia-reperfusion injury in young rats. Methods This study was divided into two experimental phases: preconditioning and…
View details →Negative / Null Result ReportOpen accessMedicine
Kesgin YM, Kaan AZ, Arslan M et al. · 2025 · World journal of emergency surgery : WJES
Background Textbook outcome (TO) is a concept that describes achieving an uneventful course for a patient undergoing surgery. It was first described for colorectal surgery and is now increasingly linked to various topics of surgical…
View details →Negative / Null Result ReportMedicine
Ishimaru T, Aihara I · 2025 · The Journal of experimental biology
Male cicadas emit sounds to attract females. The acoustic traits of calls vary among species and show unique patterns that dynamically change, even in the same bout. While the calling behavior of a single cicada has been quantified for…
View details →Negative / Null Result ReportMedicine
Francis AM, Anderson TJ, McKearney KJ et al. · 2025 · Psychiatry research. Neuroimaging
Cognitive impairment, particularly in attention and working memory, is a notable feature of schizophrenia (SZ). Individuals with SZ frequently consume high levels of caffeine, often exceeding 550 mg daily, yet the cognitive effects of this…
View details →Negative / Null Result ReportOpen accessMedicine
Yan J, Zheng W, Xie S et al. · 2025 · International dental journal
Introduction and aims Observational studies suggest an association between metabolic syndrome (MetS) and periodontitis. However, observational studies are susceptible to reverse causation and confounding factors, so the causality of this…
View details →Negative / Null Result Report
Zhang X, Liang S, Wang X et al. · 2025 · Preprint
Abstract Background Several special case of vitiligo patient with advanced pancreatic cancer was observed in our clinical practice, which prompted us to think about whether there is an association between the two diseases, and to further…
View details →Negative / Null Result ReportMedicine
Nickerson C, Wright S, Pickering L et al. · 2025 · Journal of public health (Oxford, England)
Background Bowel cancer screening in England is initially carried out using a home testing kit, with those who require further testing first being referred to an assessment clinic. During COVID-19, these assessment clinics became 'virtual'…
View details →Negative / Null Result ReportMedicine
Damtie Y, Betts K, Dachew BA et al. · 2025 · Journal of psychosomatic research
Background Limited evidence exists on the association between maternal use of antidiabetic medications and neurodevelopmental outcomes in children. This study examined the link between maternal diabetes, antidiabetic medication use, and…
View details →Negative / Null Result ReportOpen accessMedicine
Büyükdemirtaş B, Benn M, Kwon HB et al. · 2026 · Psychopharmacology
Rationale Binge drinking during adolescence is associated with a higher risk of developing Alcohol Use Disorders and impaired stress reactivity in adulthood. The hypothalamic-pituitary-adrenal axis matures during adolescence and is under…
View details →Negative / Null Result ReportMedicine
Isaacson BN, Serbin SP, Grabosky JC · 2025 · Forest Ecology and Management.
There is a vigorous debate around whether and how to manage forests for climate mitigation or for other goals such as biodiversity. To achieve any of these goals it is necessary to define the parameters within which they can exist;…
View details →Negative / Null Result ReportOpen accessMedicine
Kanyorszky ET, Sterczer Á, Vizi Z et al. · 2026 · BMC veterinary research
BACKGROUND: Acute pancreatitis triggers the production of acute-phase proteins (APPs) in the body, among which C-reactive protein (CRP) is the most extensively studied and widely used for both diagnosis and prognosis. The diagnostic value…
View details →Negative / Null Result Report
Ghamgosar Shahkhali M, Liu L, Ghamgosar Shahkhali MH et al. · 2025 · Preprint
Objective To explore potential genetic and/or causal associations between Post-Traumatic Stress Disorder and neurodegeneration-related isolated/idiopathic rapid-eye-movement sleep behavior disorder. Methods We conducted polygenic risk…
View details →Negative / Null Result ReportMedicine
Yang T, Yuan X, Gao W et al. · 2024 · Internal and emergency medicine
Observational studies revealed paradoxically inverse associations between diabetes and aortic diseases (aortic aneurysm or aortic dissection), yet the causality remains to be determined. To investigate the causal associations between…
View details →Negative / Null Result ReportOpen accessMedicine
Zhang H, Zhao T, Zheng H et al. · 2026 · BMC neurology
Neuronal intranuclear inclusion disease (NIID) is a rare, progressive neurodegenerative disorder caused by abnormal GGC repeat expansions in the NOTCH2NLC gene, leading to multisystem involvement. Electrophysiological abnormalities in NIID…
View details →Negative / Null Result ReportMedicine
Berger M, Bruggisser F, Schwarz A et al. · 2025 · Physiology & behavior
Objectives To investigate whether a single session of aerobic exercise improves inhibitory control in preadolescent children and whether this effect is mediated by changes in parasympathetic activity. Design In this experimental study, an…
View details →Failed Experiment ReportMedicine
Martinez G, Tolentino K, Sukheja P et al. · 2025 · Bioorganic & medicinal chemistry letters
Screening of the ChemDiv molecular library in cholesterol media against Mycobacterium tuberculosis (Mtb) H37Rv strain identified a novel isoxazole thiophene hit as a putative Rv1625c/Cya activator with a promising in vitro activity and…
View details →Negative / Null Result Report
Su Z, Wyble B, Fu Y · 2024 · Preprint
This study explores the relationship between working memory and attention during visual search tasks, focusing on how time constraints affect the encoding of visual information into working memory. The research is based on the premise that…
View details →Negative / Null Result ReportMedicine
de Bruin LJE, Hoegh M, Greve C et al. · 2024 · The Journal of orthopaedic and sports physical therapy
OBJECTIVE: To assess the causal role of the relationship between loading and the onset of nonspecific low back pain (NSLBP) and persistence of NSLBP (chronic low back pain [CLBP]). DESIGN : Scoping review. LITERATURE SEARCH : We searched…
View details →Negative / Null Result ReportOpen accessMedicine
· 2024 · Journal of cellular and molecular medicine
Xin Li, Hao Xu, Jianfeng Yi, Chunlu Dong, Hui Zhang, Zhengfeng Wang, Long Miao, Wence Zhou. miR-365 secreted from M2 Macrophage-derived extracellular vesicles promotes pancreatic ductal adenocarcinoma progression through the BTG2/FAK/AKT…
View details →Negative / Null Result ReportMedicine
Power MC, Lynch KM, Fang V et al. · 2025 · Environmental research
Background As dementia has a decades-long preclinical phase, earlier air pollution exposures may be more etiologically relevant to dementia risk than more recent exposures. Methods We estimated exposures at Atherosclerosis Risk in…
View details →Negative / Null Result ReportMedicine
Kömürcü HF, Sever N, Gökdereli NS et al. · 2025 · Neurological research
Background It has been suggested that smokers have higher recanalization rate, lower risk of cerebral hemorrhage and better prognosis than non-smokers (smoking paradox) after reperfusion therapy in patients with acute ischemic stroke (IS).…
View details →Negative / Null Result ReportMedicine
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of Dairy Science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
View details →Negative / Null Result Report
Xu C, Yang G, Liu Y · 2024 · Preprint
Abstract Background Obstructive Sleep apnea (OSA) is a prevalent sleep disorder characterized by repetitive interruptions of breathing during sleep, significantly impacting cardiovascular and metabolic health. Epigenetic aging, measured…
View details →Negative / Null Result ReportOpen accessMedicine
Toyoshima M, Toyofuku R, Shimoda S et al. · 2026 · Neuropsychopharmacology reports
Adolescence is a sensitive developmental stage in which exposure to addictive substances can produce long-lasting changes in the neural circuits that regulate reward. Nicotine and ethanol are frequently co-used among adolescents, and…
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