e-ISSN: Pending
Negative / Null Result ReportMedicine

Cryoneurolysis Reduces Postoperative Opioid Use in Patients Undergoing Total Knee Arthroplasty.

Toavs TL; Sudheendra VH; Barrett T; Lentine B · 2026 · The Journal of arthroplasty

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract (excerpt)

Background Cryoanalgesia is increasingly used in total knee arthroplasty (TKA) as a nonopioid pain control modality. This study evaluated the effect of cryoanalgesia on postoperative opioid use and recovery of range of motion in patients…

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Metadata source: Europe PMC · DOI 10.1016/j.arth.2026.05.026