21,742 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Dias Maile AA, Andronova E, Ball F et al. · 2026 · Preprint
Decision making often requires the integration of noisy bottom-up sensory evidence with top-down prior expectations learned from past experiences. Acetylcholine and noradrenaline have been proposed to shape these computations, yet it…
View details →Tan S, Teoh TT, Joseph P et al. · 2026 · Preprint
Abstract Scenarios involving concealed-cavity fire spread has contributed to major facade fires, dating from Knowsley Heights (1991) to Grenfell Tower (2017). However, post-Grenfell regulatory responses diverged widely, and no study has…
View details →Yu J, Eyles JP, Moreti Cabral Silveira A et al. · 2026 · BMC health services research
Background Evidence based medicine is a critical cornerstone in contemporary medicine, yet uptake and adoption of evidence remain suboptimal. This is prominent in many fields of healthcare, including musculoskeletal health and surgery.…
View details →Iuliano L, Veritti D, Lanzetta P · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Iridology is an alternative diagnostic practice that claims to identify systemic diseases and organ dysfunction through visual inspection of iris features, including pigmentation patterns, crypts, furrows, and discolorations. Despite its…
View details →Simão AC, de Oliveira MBG, Menezes Junior ADS · 2026 · Cardiology
Introduction This umbrella review aims to evaluate the certainty and consistency of the available evidence rather than to provide a new procedural comparison. We combined systematic reviews that looked at surgical septal myectomy (SM) and…
View details →Han LJ, Pan XW, Zhu J et al. · 2026 · Journal of multidisciplinary healthcare
Purpose Acute pancreatitis has complex causes, and traditional Chinese medicine plays a significant role in its treatment. However, there is a lack of standardized protocols and a comprehensive best evidence summary for rhubarb…
View details →Melendez Vassall I, Mannino JE, Watters P et al. · 2026 · Advances in neonatal care : official journal of the National Association of Neonatal Nurses
Metabolic bone disease (MBD) is a disorder affecting bone mineralization that leads to short and long-term consequences. A daily exercise regimen consisting of passive range of motion (ROM) and gentle compression of upper and lower…
View details →Fontanier V, Delforge E, Opplert J et al. · 2026 · Physical therapy
Importance Evidence-based practice (EBP) is a core competency in physical therapy. In 2015, France implemented a major reform of physical therapist education, extending training from 3 to 5 years and embedding EBP throughout the…
View details →Parisien C, Ho-El Abidi N, Khalaf E et al. · 2026 · Preprint
Addiction is a chronic, relapsing disorder comprising three stages: binge, withdrawal, and preoccupation. Preclinical evidence suggests that the habenula, a small epithalamic region, is involved across these stages and may contribute to…
View details →Williams T, Phillips NJ, Stein DJ et al. · 2026 · The Cochrane database of systematic reviews
Background Posttraumatic stress disorder (PTSD) is a prevalent and disabling disorder. Evidence that PTSD is characterised by specific psychobiological dysfunctions has contributed to a growing interest in the use of medication in its…
View details →Petri AC, Martins TB, Martins TB et al. · 2026 · Sports medicine - open
Background Gait retraining has been proposed as a strategy to modify running biomechanics and reduce symptoms in runners with patellofemoral pain (PFP). However, review-level evidence remains heterogeneous regarding clinical effects,…
View details →Mori H, Shimomura K, Miyazaki K et al. · 2026 · Preprint
Abstract Background. In Japan, much preventive medicine outside mandated national programmes is left to municipal discretion, yet the nationwide alignment between these locally administered programmes and graded evidence remains…
View details →Sugita H, Sato MT, Yamaji N et al. · 2026 · The Cochrane database of systematic reviews
Rationale Non-communicable diseases (NCDs), such as hypertension, diabetes, and asthma, require continuous medication management. However, medication adherence remains suboptimal. Telepharmacy-defined as pharmacist-led care delivered…
View details →Champion S, Bilton R, Gordon S · 2026 · Australasian journal on ageing
Objectives This study evaluated the outcomes for individuals who completed an Innovator Training Program (ITP) funded by the Commonwealth Government of Australia and delivered by Aged Care Research & Industry Innovation Australia (ARIIA).…
View details →Kloc K, Toumi M, Łukomska E et al. · 2026 · Journal of market access & health policy
The Joint Clinical Assessment (JCA) evaluates the relative effectiveness (RE) of interventions over comparators. While randomised control trials (RCTs) are considered the gold standard, single-arm trials (SATs) require an external control…
View details →Iqbal U, Manga YB, Nkhoma DE et al. · 2026 · NPJ digital medicine
Digital health interventions (DHIs) are increasingly used to strengthen patient engagement. However, despite its rapid growth, DHIs remain unevenly evaluated and poorly standardized. Six databases were searched to generate an evidence gap…
View details →Maldonado M, Boedeker P, Kusnoor AV · 2026 · The clinical teacher
Background Management reasoning (MR), the component of clinical reasoning concerned with treatment planning, patient preferences and resource considerations, develops later than diagnostic reasoning and remains underemphasised in medical…
View details →Costa T · 2026 · Frontiers in psychology
Across psychology, bold empirical claims often outpace the evidential support on which they rest. The replication crisis has shown that statistical significance alone provides little guidance about what should rationally be believed. To…
View details →Werneburg F, Zeh A, Gutteck N et al. · 2026 · Journal of bone and joint infection
Topical intrawound vancomycin powder has been widely adopted in orthopaedic surgery as an adjunct for the prevention of surgical site infection (SSI) and periprosthetic joint infection (PJI). Retrospective cohorts and derived meta-analyses…
View details →Larvie DY, Güitrón Leal CE, Venkatramanan S et al. · 2026 · The Cochrane database of systematic reviews
Rationale Vitamin B 12 deficiency is an important public health problem in children, and has been associated with anaemia and impaired growth, cognition, and development. Vitamin B 12 deficiency may develop in children due to lower content…
View details →Shu W, Zhou Y, Sun E et al. · 2026 · Journal of medical Internet research
Background Embodied intelligence-artificial intelligence instantiated in physical or virtual bodies that can perceive, communicate, and interact with users and their environments-has been increasingly applied in health care. However, the…
View details →Scurich N, Albright TD · 2026 · Proceedings of the National Academy of Sciences of the United States of America
Proficiency testing is widely used to assess expertise in medicine, engineering, and other high-stakes fields. In forensic science, such tests are often cited in court as evidence that pattern-comparison methods are accurate and reliable.…
View details →Mahon P, Körtner G · 2026 · Preprint
Abstract Measuring the effectiveness of management programmes for alien invasive predators can be difficult not least because the densities of these species are often hard to estimate. We estimated the proportion of nights ( incursion rate…
View details →Stewart JJ, Allen BS, Polutchko SK et al. · 2026 · Journal of experimental botany
Refilling of xylem embolism during recovery from drought has been studied for decades, although the legitimacy of supporting evidence has been debated in recent years due to potentially widespread methodological artifacts associated with…
View details →van der Steege AE, Humuza J, Shyirambere C et al. · 2026 · BMJ global health
Introduction The WHO Model Lists of Essential Medicines (MLEM and MLEMc) guide national medicine selection, particularly in low-income and lower middle-income countries (LMICs). Concerns exist about the adequacy and transferability of…
View details →Ganguly A, Bhowmik S, Hajra A · 2026 · Therapeutic hypothermia and temperature management
Shivering is a common complication of targeted temperature management (TTM), which could undermine its neuroprotective benefits by increasing cerebral oxygen consumption and metabolic demand. Buspirone, a 5-HT1A receptor partial agonist,…
View details →Simone J, Cooke C, Lee S et al. · 2026 · Sexually transmitted infections
Congenital syphilis (CS) has been rapidly re-emerging as a public health crisis across North America. The present standard of care treatment for CS involves a 10-day hospitalisation for intravenous penicillin G, which is costly for…
View details →Jin X, Shen T, Wang Y et al. · 2026 · JBI evidence implementation
Introduction Auditory hallucinations, persistent and distressing symptoms in patients with schizophrenia, are often poorly controlled by antipsychotics. Structured non-pharmacological interventions remain limited in routine clinical…
View details →Black CFD, Phillips C, Sanders IA et al. · 2026 · Child maltreatment
It is unclear whether research has generated causal evidence about the impact of mandatory reporting (MR) policies on reporting outcomes. This scoping review applied concepts from the NIH Stage Model to map and organize five decades of…
View details →Gao Y, Liu M, Li L et al. · 2026 · The Cochrane database of systematic reviews
Background Triple-negative breast cancer (TNBC), an aggressive subtype lacking oestrogen and progesterone receptors and amplification of HER2 receptors, accounts for 12% to 17% of breast cancers. Adjuvant and neoadjuvant chemotherapy…
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