Negative / Null Result ReportOpen accessBusiness
Farhad Rahmanov, Anar Azizov , Elnara Samedova et al. · 2026 · Knowledge & Performance Management
Type of the article: Research Article Whether national artificial intelligence (AI) ecosystem development shapes tourism’s contribution to GDP is an open empirical question, particularly given the multidimensional nature of modern AI ecosystems and the heterogeneous reliance of countries on tourism. This study identifies which dimensions of national AI ecosystem development drive within-country changes in tourism’s direct GDP share, using panel data from 33 countries over 2017–2023. Fixed-effects estimation with clustered standard errors is applied to both the composite Stanford HAI AI Vibranc
View details →Negative / Null Result ReportOpen accessMedicine
Olivier Senn, Florian Hoesl, Toni Amadeus Bechtold et al. · 2024 · PLoS ONE
There is a broad consensus in groove research that the experience of groove, understood as a pleasurable urge to move in response to music, is to some extent related to the complexity of the rhythm. Specifically, music with medium rhythmic complexity has been found to motivate greater urge to move compared to low or high complexity music (inverted-U hypothesis). Studies that confirmed the inverted-U hypothesis usually based their measure of complexity on the rhythmic phenomenon of syncopation, where rhythms with more and/or stronger syncopation are considered to be more complex than less synco
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Seref Can Gurel, Seref Can Gurel, Seref Can Gurel et al. · 2018 · Frontiers in Neuroscience
The frontal eye fields (FEFs) are core nodes of the oculomotor system contributing to saccade planning, control, and execution. Here, we aimed to reveal hemispheric asymmetries between left and right FEF in both voluntary and reflexive saccades toward horizontal and vertical targets. To this end, we applied fMRI-guided continuous theta burst stimulation (cTBS) over either left or right FEF and assessed the consequences of this disruption on saccade latencies. Using a fully counterbalanced within-subject design, we measured saccade latencies before and after the application of cTBS in eighteen
View details →Negative / Null Result ReportOpen accessMedicine
Lou qian Zhang, Jian nong Zhou, Jun Wang et al. · 2012 · PLoS ONE
BACKGROUND AND OBJECTIVES: N-Acetyltransferase (NAT) 2 is an important enzyme involved in the metabolism of different xenobiotics, including potential carcinogens, whose phenotypes were reported to be related to individual susceptibility to colorectal cancer (CRC). However, the results remain conflicting. To assess the relationship between NAT2 phenotypes and CRC risk, we performed this meta-analysis. METHODS: A comprehensive literature search was conducted to identify all case-control or cohort studies of NAT2 acetylator status on the susceptibility of CRC by searching of PubMed and EMBASE, u
View details →Negative / Null Result ReportOpen accessChiropractic
M. John Petrozzi, Grace Spencer, Martin G. Mackey · 2021 · Chiropractic & Manual Therapies
Abstract Background In chronic conditions, such as back pain, the use of interventions that address physical, social and psychological aspects within a biopsychosocial framework are encouraged, however, applying this holistic multimodal approach in physical therapy practice (i.e., chiropractic and physiotherapy) is challenging. To explore the problem of delivering a biopsychosocially informed package of care in physical therapy practice a recent randomised control trial (RCT) called ‘Mind Your Back’ was conducted to evaluate the effectiveness of a combined physical and internet-delivered psych
View details →Negative / Null Result ReportOpen accessPolitical science (General)
Baowen Liang · 2026 · Politics and Governance
Generalized trust refers to individuals’ trust in members of society at large. Previous research highlights negativity bias as a central obstacle to trust development: trust is easily destroyed but difficult to build. Yet, most evidence for this bias comes from Western, individualistic contexts. This study examines whether such findings generalize to collectivist settings. Using a preregistered online experiment in China, I show that negative information about others’ untrustworthiness lowers generalized trust more than positive information raises it, which indicates a clear negativity bias in
View details →Negative / Null Result ReportOpen accessMedicine
Gabriel Gaudencio Rêgo, Óscar F. Gonçalves, Paulo Sérgio Boggio · 2022 · Scientific Reports
Abstract Neurofeedback and transcranial Direct Current Stimulation (tDCS) are promising techniques for neuroenhancement of attentional performance. As far as we know no study compared both techniques on attentional performance in healthy participants. We compared tDCS and neurofeedback in a randomized, single-blind, controlled experiment assessing both behavioral (accuracy and time reaction) and electrophysiological (N1, P1, and P3 components) data of participants responding to the Attention Network Task (ANT). Eighty volunteers volunteered for this study. We adopted standard protocols for bot
View details →Negative / Null Result ReportOpen accessSpecial aspects of education
Alistair McInerny, Andrew Boudreaux, Mila Kryjevskaia · 2025 · Physical Review Physics Education Research
This article reports on a controlled study to investigate the efficacy of incorporating explicit discussions about the duality of human reasoning and its implications for learning in physics instruction. The central goal is to probe to what extent, if at all, such discussions improve student performance on tasks that tend to elicit intuitively appealing but incorrect responses. We hypothesized that explicitly discussing the reasoning pathways and hazards associated with the interactions between automatic process 1 and deliberate process 2 could boost students’ performance on a variety of topic
View details →Negative / Null Result ReportOpen accessPolitical science (General)
Jason M. Pudlo · Politics and Religion
Houses of worship are often shelters after the storm. Yet, as climate change fuels natural disasters and communities increasingly rely on congregations during disaster recovery, are houses of worship ready to be houses of refuge? Examining clergy influence, does a higher concern about climate change by clergy result in improved congregational disaster readiness? Data for the study come from a 2019 nationwide survey of clergy. The survey includes measures of congregational disaster preparedness along with one of the first applications of the SASSY climate concern measure to clergy. Results show
View details →Negative / Null Result ReportOpen accessMedicine
Rogier A. Kievit, Delia Fuhrmann, Gesa Sophia Borgeest et al. · 2018 · Wellcome Open Research
Background: Fluid intelligence declines with advancing age, starting in early adulthood. Within-subject declines in fluid intelligence are highly correlated with contemporaneous declines in the ability to live and function independently. To support healthy aging, the mechanisms underlying these declines need to be better understood. Methods: In this pre-registered analysis, we applied latent growth curve modelling to investigate the neural determinants of longitudinal changes in fluid intelligence across three time points in 185,317 individuals (N=9,719 two waves, N=870 three waves) from the U
View details →Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Sebastian Baecke, Ralf Lützkendorf, Johannes Bernarding · 2026 · Brain Sciences
Background: The efficacy of real-time fMRI neurofeedback (NFB) depends critically on how feedback is presented and perceived by the participant. Although various visual feedback designs are used in practice, there is limited evidence on the impact of modality on learning and performance. We conducted a feasibility study to compare the effectiveness of different feedback modalities, and to evaluate the technical performance of NFB across two scanner field strengths. Methods: In a single-session study, nine healthy adults (6 men, 3 women) voluntarily adapted the activation level of the primary s
View details →Negative / Null Result ReportOpen accessMedicine
Hannah A Edwards, Gabriela K Hajduk, Gillian Durieux et al. · 2015 · PLoS ONE
Consistency of between-individual differences in behaviour or personality is a phenomenon in populations that can have ecological consequences and evolutionary potential. One way that behaviour can evolve is to have a genetic basis. Identifying the molecular genetic basis of personality could therefore provide insight into how and why such variation is maintained, particularly in natural populations. Previously identified candidate genes for personality in birds include the dopamine receptor D4 (DRD4), and serotonin transporter (SERT). Studies of wild bird populations have shown that explorato
View details →Negative / Null Result ReportOpen accessLanguage and Literature
Matt Hunt Gardner, Xinyu Leslie Liao · 2026 · Language and Cognition
Using 3,154 tokens from American English, we test whether optionality in verb–particle placement increases speech-planning cost, measured as pre-verbal silence. Tokens were coded for object properties, idiomaticity and verb frequency. We find that pre-verbal silence does not differ between split (pick the book up) and joined (pick up the book) orders. While idiomaticity favours the joined order, it does not raise planning cost. Verb frequency shortens pauses only in fast speech, suggesting predictability acts lexically, not structurally. Choice symmetry does not lengthen pauses. We therefore f
View details →Negative / Null Result ReportOpen accessMedicine
Philipp Schoenegger, Miguel Costa-Gomes · 2022 · PLoS ONE
Charities differ, among other things, alongside the likelihood that their interventions succeed and produce the desired outcomes and alongside the extent that such likelihood can even be articulated numerically. In this paper, we investigate what best explains charitable giving behaviour regarding charities that have interventions that will succeed with a quantifiable and high probability (sure-thing charities) and charities that have interventions that only have a small and hard to quantify probability of bringing about the desired end (probabilistic charities). We study individual difference
View details →Negative / Null Result ReportOpen accessPhysics
Martin Tajmar, Lance L. Williams · 2020 · Physics
Kaluza was the first to realize that the four-dimensional gravitational field of general relativity and the classical electromagnetic field behave as if they were components of a five-dimensional gravitational field. We present a novel experimental test of the macroscopic classical interpretation of the Kaluza fifth dimension. Our experiment design probes a key feature of Kaluza unification—that electric charge is identified with motion in the fifth dimension. Therefore, we tested for a time dilation effect on an electrically charged clock. This test can also be understood as a constraint on t
View details →Negative / Null Result ReportOpen accessSocial sciences (General)
Martijn van der Meer · 2025 · Journal of Trial and Error
Expert endorsement seems a promising tool in countering vaccine hesitancy. Yet findings from an experiment in the United Kingdom, published in this journal, found that repeated expert‐backed “debunking” messages had little effect on vaccination intentions or behaviors. At the same time, a similar study in Italy had earlier observed a slight increase in the intent to vaccinate—despite actual uptake remaining unchanged. In this article, I reflect on the differences between these studies and argue for a situated public health approach: one that opens up on diversity and responds to local trust dy
View details →Negative / Null Result ReportOpen accessScience
Tianhao Liu, Katharina Rolfs, Isaac Fan et al. · 2021 · New Journal of Physics
By measuring the spin precession frequencies of polarized ^129 Xe and ^3 He, a new upper limit on the ^129 Xe atomic electric dipole moment (EDM) ${d}_{\text{A}}\left({}^{129}\mathrm{X}\mathrm{e}\right)$ was reported in Sachdev et al (2019 Phys. Rev. Lett. 123 , 143003). Here, we propose a new evaluation method based on global phase fitting (GPF) for analyzing the continuous phase development of the ^3 He– ^129 Xe comagnetometer signal. The Cramer–Rao lower bound on the ^129 Xe EDM for the GPF method is theoretically derived and shows the potential benefit of our new approach. The robustness o
View details →Negative / Null Result ReportOpen accessMedicine
Rogier A. Kievit, Delia Fuhrmann, Gesa Sophia Borgeest et al. · 2018 · Wellcome Open Research
Background: Fluid intelligence declines with advancing age, starting in early adulthood. Within-subject declines in fluid intelligence are highly correlated with contemporaneous declines in the ability to live and function independently. To support healthy aging, the mechanisms underlying these declines need to be better understood. Methods: In this pre-registered analysis, we applied latent growth curve modelling to investigate the neural determinants of longitudinal changes in fluid intelligence across three time points in 185,317 individuals (N=9,719 two waves, N=870 three waves) from the U
View details →Negative / Null Result ReportOpen accessEducation
Nicole Shechtman, Jeremy Roschelle, Mingyu Feng et al. · 2019 · AERA Open
The Math Curriculum Impact Study was a large-scale randomized controlled trial (RCT) to test the efficacy of a digital core curriculum for Grade 5 mathematics. Reasoning Mind’s Grade 5 Common Core Curriculum was a comprehensive, adaptive, blended learning approach that schools in the treatment group implemented for an entire school year. Schools in the control group implemented their business-as-usual mathematics curriculum. The study was completed in 46 schools throughout West Virginia, resulting in achievement data from 1,919 students. It also included exploratory investigations of teacher p
View details →Negative / Null Result ReportMedicine
Chen X, Wen W, Zheng L · 2026 · Shock (Augusta, Ga.)
Background Sepsis is a clinical syndrome marked by a dysregulated host response to infection, impairing oxygen delivery and utilization and causing organ dysfunction. Hypoxemia, which can cause significant tissue and organ damage, commonly…
View details →Negative / Null Result ReportOpen accessMedicine (General)
Hiroyuki Masaoka, Keitaro Matsuo, Isao Oze et al. · 2020 · Journal of Epidemiology
Background: The association of alcohol drinking with bladder cancer risk remains unclear in East Asian populations. Aldehyde dehydrogenase 2 (ALDH2) enzyme oxidizes alcohol-metabolized carcinogenic acetaldehyde into acetate. It is well known that the inactive ALDH2 carriers, specific to East Asian populations, have an increased risk of several cancer types because of increased exposure to acetaldehyde after alcohol consumption. The aim of this study was to examine the association between alcohol drinking and bladder cancer risk using data from ten population-based prospective cohort studies in
View details →Negative / Null Result ReportOpen accessMedicine
Nicholas Judd, Rogier Kievit · 2025 · eLife
Education is related to a wide variety of beneficial health, behavioral, and societal outcomes. However, whether education causes long-term structural changes in the brain remains unclear. A pressing challenge is that individuals self-select into continued education, thereby introducing a wide variety of environmental and genetic confounders. Fortunately, natural experiments allow us to isolate the causal impact of increased education from individual (and societal) characteristics. Here, we exploit a policy change in the UK (the 1972 ROSLA act) that increased the amount of mandatory schooling
View details →Negative / Null Result ReportOpen accessSpecial aspects of education
علي عبدالله علي مسافر · 2016 · مجلة التربیة الخاصة والتأهیل
تهدف الدراسة الحالية إلى استقصاء الضغوط المهنية لمعلمي التربية الخاصة في کل من البيئة الثقافية السعودية والمصرية، ومعرفة الفروق في نوعية تلک الضغوط في هاتين البيئتين تبعاً لمتغيرات فئة الإعاقة التي يعمل معها المعلم (عقلية وتوحد/ بصرية/ سمعية)، وجنس المعلم (ذکر/ أنثى)، وسنوات خبرة المعلم (أقل من 5 سنوات/ 5 سنوات فأکثر). وأجريت الدراسة على عينة قوامها (224) معلماً ومعلمةً من معلمي التربية الخاصة بجمهورية مصر العربية والمملکة العربية السعودية، واستخدمت الدراسة مقياس الضغوط المهنية لمعلمي التربية الخاصة (إعداد الباحث)، ولتحليل البيانات تم تطبيق اختبار "ت"، وتحليل التباين المتعدد MANOVA، واختبار شي
View details →Negative / Null Result ReportOpen accessMedicine
Seyyed Abolfazl Tabatabaie-Zadeh, Nazanin Mahdavi, Behnaz Mahdaviani et al. · 2024 · PLoS ONE
Purpose Oral cancers are the 6th most common malignancy worldwide and oral squamous cell carcinoma, comprises over 90% of oral cancers. This study investigates the relationship between physical activity level during the lifetime and oral squamous cell carcinoma risk. Methods 100 oral squamous cell carcinoma patients and 200 healthy individuals participated in this case-control study. Physical activity level was evaluated via the Lifetime Physical Activity Questionnaire. The occupational, household, and sports domains of lifetime physical activity were determined. Case and control groups' parti
View details →Negative / Null Result ReportOpen accessMedicine (General)
Lisa Argnani, Anna Zanetti, Anna Zanetti et al. · 2021 · Frontiers in Medicine
Background: Rheumatoid arthritis (RA) is associated with an increase in cardiovascular (CV) risk. This issue maybe not only explained by a genetic component, as well as by the traditional CV risk factors, but also by an underestimation and undertreatment of concomitant CV comorbidities.Method: This was a retrospective matched-cohort analysis in the Italian RA real-world population based on the healthcare-administrative databases to assess the CV risk factors and incidence of CV events in comparison with the general population. Persistence and adherence to the CV therapy were also evaluated in
View details →Abandoned HypothesisOpen accessMedicine (General)
Homayoun Sadeghi-Bazargani, Ali Jafari-Khounigh, Hamid Sharifi et al. · 2025 · Russian Open Medical Journal
Background — Travel restrictions and adhering to health protocols while traveling was among the key strategies to combat COVID-19 pandemic. Objective — The present study aims to measure and evaluate travel patterns and compliance with COVID-19 prevention protocols during traveling. Methods — In this cross-sectional study, 589 individuals from the capitals of six provinces of Iran were included in the study using the cluster sampling method. There were 40 clusters. For data analysis, the mean value of responses in each individual was calculated for each section of the questionnaire. Results — T
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Grynchuk F, Horditsa V · 2026 · Preprint
Abstract Objective Early detection of bowel necrosis and peritonitis is crucial for choosing a treatment strategy in patients with acute small bowel obstruction (ASBO). The aim of this study was to evaluate the effect of comorbidity on the…
View details →Abandoned HypothesisOpen accessEducation
Walid Samir Ahmed Ismail Gharib, Prof. Dr. Hayam Saber Shaheen · 2023 · مجلة بحوث التعليم والإبتكار
This study aimed at exploring the relationship between Hermann's brain dominance and habits of mind in class management for preparatory stage teachers, in addition to examining the difference in the study variables according to the demographic variables, gender (males-females), and the number of years of experience (less than 5 years, 5-10 years, 10-15 years, 15 years or more). The methodology and procedures of the study are based on the comparative descriptive relational approach. The study sample consisted of (107) male and female teachers, whose ages ranged between (25-60) years, with an av
View details →Negative / Null Result ReportOpen accessMedicine
Renata Jabłońska, Marta Gralik, Agnieszka Królikowska et al. · 2016 · Pielęgniarstwo Neurologiczne i Neurochirurgiczne
Introduction. In the occupational medicine back pain is treated as a paraoccupational disease, mainly related to specific professional groups. They include those employed in the sector of health care, who are at the highest risk of developing back pain, nurses in particular. Aim. Assessment of back pain occurrence among nurses and determining the factors affecting this condition. Material and Methods. The study group consisted of 76 nurses working in neurology and neurosurgery wards/clinics. The research methodology applied consisted of diagnostic survey method, and as the technique, a survey
View details →Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Kinga Mate, Pedro de Pablos-Rodríguez, Marta Burbano Herraiz et al. · 2026 · International Brazilian Journal of Urology
ABSTRACT Purpose: Focal cryotherapy is a minimally invasive treatment for localized prostate cancer (PCa), but its oncological outcomes, particularly in relation to baseline Gleason Grade Group (GG), remain understudied. This study evaluates its efficacy and the impact while radical of baseline Gleason score on recurrence-free survival. Materials and Methods: A retrospective analysis included 111 patients with localized PCa treated with focal cryotherapy between 2014 and January 2024. Patients with prior treatments or follow-up 1. Results: Median follow-up was 35 months (IQR 24–49). Confirmato
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