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WASTE Journal

Browse the failure-mode index

21,294 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Cognitive Therapy vs. Short-Term Dynamic Psychotherapy in a Community Mental Health Setting: A Preliminary Analysis of Effects in Several Severity Domains.

Gibbons MBC, Kodkany N, Liow Y et al. · 2026 · Clinical psychology & psychotherapy

Objective To investigate the effectiveness of cognitive therapy (CT) and short-term dynamic psychotherapy (STDP) among patients with greater severity, defined in several ways, in a community mental health setting. Method Using data from a…

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Negative / Null Result ReportMedicine

White matter integrity and verbal memory following a first episode of psychosis: A longitudinal study.

Ghanem J, Totzek JF, Henri-Bellemare C et al. · 2025 · Progress in neuro-psychopharmacology & biological psychiatry

Psychotic disorders are heterogeneous disorders for which there is evidence of structural and functional brain abnormalities. The role of white matter integrity, often measured via Fractional Anisotropy (FA), has played a controversial…

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Negative / Null Result ReportOpen accessMedicine

Plasma Neurofilament Light Chain Is Associated with Cognitive Functions but Not Patient-Reported Outcomes in Multiple Sclerosis.

Nicolella V, Novarella F, Falco F et al. · 2025 · Neurology international

Objective We aimed to explore associations between plasma neurofilament light chain (pNfL) and cognition through patient-reported outcomes (PROs) in multiple sclerosis (MS). Methods In this cross-sectional study, we included 211 people…

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Negative / Null Result ReportOpen accessMedicine

Cryoanalgesia to treat phantom limb pain following a trans-femoral (above-knee) amputation: a randomized, sham-controlled pilot study.

Ilfeld BM, Finneran JJ, Abdullah B et al. · 2026 · Regional anesthesia and pain medicine

Background A previous clinical trial applied percutaneous cryoneurolysis to lower limb amputees with phantom pain. The primary outcome measure was negative, but a secondary analysis suggested that patients with a below-knee amputation…

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Negative / Null Result ReportMedicine

Face masks and protection against COVID-19 and other viral respiratory infections: Assessment of benefits and harms in children.

Sandlund J, Duriseti R, Ladhani SN et al. · 2025 · Paediatric respiratory reviews

Mask mandates for children were implemented at schools and childcare centers during the COVID-19 pandemic, and the US continues to recommend masking down to the age of two in certain settings. Medical interventions should be informed by…

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Negative / Null Result ReportOpen accessMedicine

Progestogen supplementation to prevent miscarriage: Evidence and controversies.

Saccone G, Berghella V, Gulersen M et al. · 2026 · International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Progesterone plays a key role in the establishment and maintenance of pregnancy and its deficiency has been associated with early pregnancy loss. Progestogen supplementation has therefore been widely investigated as a preventive strategy…

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Negative / Null Result ReportMedicine

Semantic facilitation in blocked picture categorization: Some data and considerations regarding task selection.

Wöhner S, Luckow J, Brandt M et al. · 2024 · Journal of experimental psychology. Human perception and performance

Semantic context effects in picture naming and categorization tasks are central to the development and evaluation of current models of word production. When pictures are named in a semantically blocked context, response latencies are…

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Negative / Null Result ReportMedicine

Do uncontrolled processes contribute to evaluative learning? Insights from a new two-US process dissociation procedure and ambivalence measures.

Béna J, Lacassagne D, Corneille O · 2025 · Quarterly journal of experimental psychology (2006)

The contribution of uncontrolled processes to evaluative learning has been examined in evaluative conditioning procedures by comparing evaluations of conditioned stimuli between tasks or within tasks but between learning instruction…

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Negative / Null Result ReportOpen accessMedicine

Same Sentences, Different Grammars, Different Brain Responses?: An MEG Study on Case and Agreement Encoding in Hindi and Nepali Split-Ergative Structures.

Chacón DA, Shrestha S, Dillon BW et al. · 2026 · Neurobiology of language (Cambridge, Mass.)

At first glance, the brain's language network appears to be universal, but languages clearly differ. Does the brain adapt to the specific details of individual grammatical systems? Here, we present a magnetoencephalography (MEG) study on…

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Negative / Null Result ReportMedicine

Does sensitive skin lie in epidermal barrier impairment or abnormalities? Results from an observational study assessing biophysical parameters.

Borghi A, Guarneri F, Pacetti L et al. · 2024 · Italian journal of dermatology and venereology

Background The pathophysiology of sensitive skin is largely unknown and no univocal data on the role of the epidermal barrier impairment have been identified. The aim of this study was to assess whether subjects with or without sensitive…

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Negative / Null Result ReportOpen accessMedicine

An Exploratory Pilot Study to Investigate the Potential Relationship Between Porcine Reproductive and Respiratory Syndrome (PRRS) Virus Viremia Changes and Barn Manure Pit Management Procedures.

Melini CM, Kikuti M, Yue X et al. · 2026 · Pathogens (Basel, Switzerland)

Porcine reproductive and respiratory syndrome virus (PRRSV)-positive pigs can be exposed to high concentration of gases, such as ammonia and hydrogen sulfide when manure and urine stored in the pits beneath them is agitated and pumped.…

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Negative / Null Result ReportOpen accessMedicine

Overconfidence, Time-on-Task, and Medical Errors: Is There a Relationship?

Al-Maghrabi M, Mamede S, Schmidt HG et al. · 2024 · Advances in medical education and practice

Background Literature suggest that physicians' high level of confidence has a negative impact on medical decisions, and this may lead to medical errors. Experimental research is lacking; however, this study investigated the effects of high…

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Negative / Null Result ReportMedicine

Relationship between facility type and bulk tank milk bacteriology, udder health, udder hygiene, and milk production on Vermont organic dairy farms.

Jeffrey CE, Andrews T, Godden SM et al. · 2024 · Journal of dairy science

The primary objective of this cross-sectional observational study was to determine whether bulk tank milk quality, udder health, udder hygiene, and milk production outcomes were associated with facility type on organic dairies. A secondary…

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Failed Experiment ReportOpen accessMedicine

Clinical efficacy of subsensory sacral neuromodulation in adults with faecal incontinence: The SUBSoNIC crossover randomised controlled trial and cohort follow-up study.

Vollebregt PF, Goh YL, Bagul A et al. · 2025 · Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Aim Sacral neuromodulation (SNM) is considered the first-line surgical treatment in adults with refractory faecal incontinence (FI). However, its clinical efficacy has not been rigorously tested in a trial setting. Method Randomised,…

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