e-ISSN: Pending
WASTE Journal

Browse the failure-mode index

21,290 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Effects of supplementing crude protein to feedlot bison heifers using canola meal or wheat-based distillers' grains with solubles on feed intake, performance and carcass traits.

Alcivar de Lucca J, McKinnon JJ, Feist MS et al. · 2025 · Translational animal science

This study evaluated how varying crude protein levels in rations that incorporated canola meal or wheat-based dried distillers' grains with solubles as alternative protein sources affected growth performance, carcass traits, and liver…

View details →
Negative / Null Result ReportOpen accessMedicine

A Phase 2a Study of the Early Bactericidal Activity of Rifampicin in Combination With Meropenem Plus Amoxicillin/Clavulanate Among Adults With Rifampicin-Resistant Pulmonary Tuberculosis.

de Jager V, Mockeliunas L, You H et al. · 2025 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Background In vitro, meropenem is shown to restore the activity of rifampicin in rifampicin-resistant Mycobacterium tuberculosis strains. This phase 2a trial aimed to determine if addition of rifampicin increases the early bactericidal…

View details →
Negative / Null Result ReportMedicine

Extended Reichardt's Dye-Synthesis and Solvatochromic Properties.

Franzese S, Saker Neto N, Wong WWH · 2024 · Chemistry (Weinheim an der Bergstrasse, Germany)

Three new pyridinium-phenolate dyes based on the benchmark solvatochromic dye Betaine 30 were synthesised. The dyes contained phenylene spacers between the donor and acceptor groups. Their UV-Vis absorption spectra were measured, with the…

View details →
Negative / Null Result ReportMedicine

Investigating the impact of surface treatments on tensile bond strength between pediatric prefabricated zirconia crowns and primary maxillary incisors with various types of luting cement: an in vitro study.

Chinadet W, Pengpue P, Chaijareenont P · 2024 · European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry

Purpose This study aimed to evaluate the effects of two surface treatments on the tensile bond strength of prefabricated zirconia crowns (PZCs) using bioactive and resin cements. Methods Forty extracted human primary maxillary incisors…

View details →
Negative / Null Result ReportMedicine

Rheological properties, microstructure, and encapsulation efficiency of inulin-type dietary fiber-based gelled emulsions at different concentrations.

Gomes A, Costa ALR, Fasolin LH et al. · 2025 · Carbohydrate polymers

Gelled emulsion systems offer promising matrices for encapsulating bioactive compounds, enhancing stability, bioavailability, and controlled release. Incorporating inulin-type dietary fibers into emulsion-filled gels can innovate food…

View details →
Negative / Null Result ReportOpen accessMedicine

Randomized Phase I/II Clinical Trial of a Melanoma Helper Peptide Vaccine with or without Systemic Agonistic Anti-CD27 Antibody (Varlilumab).

Ninmer EK, Petroni GR, Gaughan E et al. · 2026 · Cancer research communications

Purpose This randomized phase I/II clinical trial (NCT03617328) was designed to test whether administration of systemic agonistic anti-CD27 antibody (varlilumab) concurrent with a melanoma vaccine is safe and enhances vaccine…

View details →
Negative / Null Result ReportOpen accessMedicine

Long-Term Outcomes of Trauma Patients After Treatment With Prehospital Tranexamic Acid: A Subgroup Analysis From the PATCH-Trauma Trial.

Mitra B, MacKenzie S, Bourke EM et al. · 2026 · Journal of the American College of Emergency Physicians open

Objectives The aim of this study was to assess 24-month functional outcomes of patients randomly assigned to prehospital tranexamic acid (TXA) compared with those assigned to placebo. Methods The PATCH-Trauma trial assessed administration…

View details →
Negative / Null Result ReportMedicine

Targeting Oral Tissue Regeneration With Standardized Centella asiatica Extract: Experimental Insights From Human Fibroblast Cultures.

Değirmenci A, Bayar Muluk N, Budak Z et al. · 2026 · The Journal of craniofacial surgery

Objectives The possible cytotoxic effect of Centella asiatica extract on human dermal fibroblast cells was examined in this cell culture experiment. The main objective was to determine its basic safety for potential use in oral tissue…

View details →
Negative / Null Result ReportMedicine

The Effect of 6 Months of Dietary Counselling on Sleep Outcomes Among Patients With Cardiovascular Diseases: A Randomised Controlled Trial.

Verkaar AJCF, van Damme I, van Veldhuisen ER et al. · 2026 · Journal of sleep research

Sleep problems are highly prevalent among patients with cardiovascular diseases (CVD). We examined the effect of dietary counselling on sleep outcomes among patients with CVD. We performed secondary analyses within a previously conducted…

View details →
Negative / Null Result ReportMedicine

Volume-Stable Collagen Matrix With or Without Platelet-Rich Fibrin Impregnation for Multiple Gingival Recessions: A Randomized Clinical Trial.

Magrin GL, Michels R, Gil ACK et al. · 2026 · Journal of periodontal research

Aim This split-mouth randomized clinical trial aimed to assess whether incorporating platelet-rich fibrin (PRF) into a volume-stable collagen matrix results in superior reduction of recession depth after 6 months of healing in the…

View details →
Replication FailureMedicine

Evidence of a limit to benefits from culling lionfish.

Hyman AC, Albins MA, Curtis JS et al. · 2026 · Scientific reports

Biological invasions threaten ecosystems worldwide, with invasive predators such as lionfish (Pterois spp.) altering marine communities through predation, competition, and habitat disruption. Since their introduction to the western…

View details →
Replication FailureMedicine

Implementation of a New MRI Contrast Policy at a Large Hospital System: Access to Contrast-Enhanced MRI and Development of NSF in Patients with Renal Insufficiency.

Ludwig DR, Zhang F, Minor B et al. · 2026 · Academic radiology

Rationale and objectives To evaluate access to contrast-enhanced MRI among patients with acute or chronic renal failure after implementation of a more permissive contrast policy and determine whether any patients developed nephrogenic…

View details →
Negative / Null Result ReportMedicine

Photobiomodulation for Pain, Healing, and Analgesic Use after Perineal Lacerations: A Double-Blind Randomized Controlled Trial.

de Castro T, Viana LH, Botelho S et al. · 2026 · International urogynecology journal

Introduction and hypothesis Approximately 60% of women experience some degree of perineal laceration following vaginal delivery. Although there is evidence supporting the use of photobiomodulation (PBM) for pain relief and wound healing in…

View details →
Negative / Null Result ReportMedicine

Rectus femoris graft harvest for anterior cruciate ligament reconstruction does not result in selective rectus femoris muscle volume loss or strength deficit at one year: quantitative magnetic resonance imaging, isokinetic and functional analyses.

Okutan AE, Kehribar L, Gürün E et al. · 2026 · International orthopaedics

Purpose To evaluate 1-year clinical and functional outcomes, as well as donor-site morbidity based on quadriceps muscle morphology, after primary single-bundle ACLR using a quadrupled RF tendon autograft. Methods Patients who underwent…

View details →
Negative / Null Result ReportOpen accessMedicine

From cool to non-cool: California's 'non-menthol' cigarettes in 2025.

Jabba SV, Erythropel HC, Anastas PT et al. · 2026 · Tobacco prevention & cessation

Since late 2022, the sale of most flavored tobacco products has been prohibited in California, including menthol cigarettes. Tobacco companies responded by introducing 'non-menthol' cigarettes in which menthol was replaced with WS-3, an…

View details →
Negative / Null Result ReportMedicine

The Influence of Heart Failure and Ventilatory Support Mode on Hospital Morbidity and Mortality in Patients With or at Risk of Obesity Hypoventilation Syndrome: Findings From the National Inpatient Sample.

Kaw R, Shekhar S, Mehra R et al. · 2026 · Chest

Background Heart failure (HF) is common in obesity hypoventilation syndrome (OHS). We explored the impact of HF on in-hospital outcomes of patients with or at risk of OHS who were treated with mechanical ventilation (MV), noninvasive…

View details →