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Browse the failure-mode index

21,290 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Profiles of Parental Self- and Child-Focused Emotion Regulation: Longitudinal Associations With Parental Exhaustion, Children’s Internalizing Problems, Children’s Achievement, and the Parent–Child Relationship

Jordan G, Stockinger K, Schiltz C et al. · 2025 · Preprint

Parenting is an emotion-eliciting experience that requires parents to navigate the dual demands of regulating their own and their children’s emotions. However, patterns of such self- and child-focused emotion regulation (ER) and their…

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Negative / Null Result Report

Long-Term Outcomes of Childhood ADHD Stimulant Use Trajectories

Plas Nvd, Noordermeer S, Hartman C et al. · 2025 · Preprint

Background. Stimulant medication is the first-line pharmacological treatment option for children with attention-deficit/hyperactivity disorder (ADHD). However, long-term effects remain unclear. Therefore, we explored long-term (>12 years)…

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Negative / Null Result ReportMedicine

Container Mosquito Abundance in Brooklyn Community Gardens.

Kelley AT, Boger R · 2025 · EcoHealth

Community gardens in urban Brooklyn, New York are social spaces that provide food sovereignty to many New Yorkers, but the arrival of the mosquito Aedes albopictus and longtime presence of Culex pipiens makes socializing in these spaces…

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Negative / Null Result ReportMedicine

Views of aging and symptoms of posttraumatic stress disorder among older adult war veterans in the context of renewed war.

Avidor S, Shenkman G, Shrira A et al. · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives For aging combat veterans, experiencing renewed war in old age can exacerbate coping with age-related challenges. The present study sought to examine how past and current war-related stressors affect long-term trajectories of…

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Negative / Null Result ReportMedicine

Does earlier mobilization reduce venous thromboembolism after spine surgery?

Ng MK, Mathew J, Dalton J et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

PURPOSE: Venous thromboembolism (VTE) is an uncommon but potentially devastating complication following spine surgery. Although early mobilization is encouraged as a preventive measure, the influence of inpatient physical therapy on VTE…

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Negative / Null Result ReportMedicine

Association of QTc Dispersion with Mortality, Intensive Care Unit Admission, Intubation, and Hospital Stay Duration in Acute Methadone Poisoning.

Taherkhani A, Yeganegi H, Tavasol A et al. · 2026 · Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir

Objective The objective of this study is to investigate the prognostic significance of QTc dispersion (QTcd) in patients with acute methadone poisoning and its association with critical clinical outcomes, including mortality, Intensive…

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Negative / Null Result ReportMedicine

Systematic reexamination of early verb dominance: Verbal and nonverbal characteristics of caregiver input and their contribution to long-term language outcomes.

Kim M, Mun J, Kim G et al. · 2026 · Developmental psychology

Early language input to infants varies in lexical composition across languages and contexts. For instance, American-English input emphasizes nouns more than verbs, while Mandarin Chinese and Korean inputs provide more verbs than nouns, the…

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Negative / Null Result ReportMedicine

Social attunement and alcohol use: The role of age and gender.

Romein C, Colyer-Patel K, Kroon E et al. · 2026 · Addictive behaviors

Background Alcohol use typically peaks during adolescence and early adulthood, when its social reinforcement value is high, and then decreases as individuals take on more adult-like responsibilities. The present study investigates whether…

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Negative / Null Result ReportMedicine

Personality profiles and trauma history in ketamine therapy for mood and anxiety disorders: A latent profile analysis of short-term outcomes.

Gregoire N, Klukas E, Kaseweter K et al. · 2025 · Psychopharmacology

Rationale Ketamine-assisted therapy is emerging as a fast-acting intervention for treatment-resistant depression and anxiety. However, individual response to treatment varies, and little is known about how personality traits and trauma…

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Negative / Null Result ReportMedicine

Intravenous Bolus Fluid Therapy Versus No Fluid Therapy Prior to Pericardiocentesis in Dogs: A Randomized Controlled Trial in 30 Dogs.

Jones N, Humm K, Tinson EW · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Objective To determine the cardiovascular and respiratory effects of bolus IV isotonic crystalloid fluid therapy before pericardiocentesis in dogs with pericardial effusion. Design Prospective, randomized, nonblinded clinical trial…

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Negative / Null Result ReportMedicine

Hemolysis and Acute Kidney Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Patients With Preexisting Renal Dysfunction.

Volleman C, Phelp PG, Dubelaar DPC et al. · 2026 · Journal of cardiothoracic and vascular anesthesia

Objectives Acute kidney injury (AKI) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). This study investigated whether cell-free hemoglobin (CFHb) levels after CPB are associated with endothelial damage…

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Negative / Null Result ReportMedicine

How Do Sex and Family SES Influence the Relation Between School Well-Being and Academic Domains? A Multi-Group Cross-Lagged Panel Analysis from Fifth To Eighth Grade.

Rémeau M, Raffy G, Borst G · 2026 · Journal of youth and adolescence

Although the association between academic achievement and well-being has been widely studied in cross-sectional and correlational studies, prior research has rarely clarified the directionality of these links by adopting a longitudinal…

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Negative / Null Result ReportMedicine

Relative influence of paraspinal muscularity and underlying bone quality on proximal junctional kyphosis and failure mode in patients undergoing thoracolumbar instrumented fusion.

Pennington Z, Mikula AL, Hamouda A et al. · 2026 · Clinical neurology and neurosurgery

Objective To assess paraspinal muscularity and bone quality contribution to PJK risk. Methods Defining PJK as ≥ 10° increase in proximal junctional angle from first upright radiograph, thoracolumbopelvic fusion patients experiencing PJK…

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Negative / Null Result ReportMedicine

Baseline electrophysiological markers of reward and error processing are associated with improved outcomes in prize-based contingency management.

Forster SE, Forman SD, Dickey MW et al. · 2026 · Drug and alcohol dependence

Background Veterans are disproportionately affected by cocaine use disorder (CUD), a condition without approved pharmacotherapies, marked by high return to use rates. Prize-Based Contingency Management (PBCM) is an effective behavioral…

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Negative / Null Result ReportMedicine

Longitudinal Associations between Mattering Dimensions and Loneliness in Adolescents: Bidirectional Effects at between- and Within-Person Levels.

Li HM, Flett GL, Cao CH et al. · 2026 · Journal of youth and adolescence

Although cross-sectional research links mattering to reduced adolescent loneliness, longitudinal studies examining temporal dynamics and distinctions between analytical levels or mattering dimensions are scarce. Without understanding…

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Negative / Null Result ReportMedicine

Subjective well-being mediates the longitudinal effect of insomnia symptoms on internalizing symptoms in community-dwelling older adults.

Ying Y, Meng R, Xu J et al. · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives The associations between insomnia symptoms and internalizing symptoms are well-established, particularly in older adults; however, the mediating factors remain inconsistent. This study seeks to explore the longitudinal…

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