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Browse the failure-mode index

21,287 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Effect of conventional warm-up versus stretching warm-up on physical performance in children soccer players: a randomized crossover trial.

Hernandez-Martínez J, Cid-Calfucura I, Perez-Carcamo J et al. · 2026 · Frontiers in physiology

Introduction To evaluate the effects of the conventional warm-up (CC) compared to warm-ups that included static (SSC), dynamic (DSC), or ballistic (BSC) stretching on jump performance (CMJ, SJ, DJ), curve sprint speed, agility (ICODT), and…

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Negative / Null Result ReportOpen accessMedicine

Assessment of pain and post-injection induration in children: A comparative study of cold application, manual pressure, and shot blocker techniques.

Sasireka V, Bhuvaneswari G, Babu S · 2026 · Journal of education and health promotion

Background Intramuscular (IM) injections are widely used in pediatric care but often cause pain and distress. Effective management is essential to improve children's healthcare experiences. Non-pharmacological methods, including Cold…

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Negative / Null Result ReportOpen accessMedicine

Critical care ultrasound evaluation of snuffbox artery vascular tension: a prospective observational study between healthy volunteers and intensive care unit patients.

Qin Y, Zhu Y, Dai X et al. · 2026 · Frontiers in medicine

Background Systemic vascular resistance is conventionally assessed using invasive methods; the snuffbox artery resistance index (RI) is a superior non-invasive predictor of lactate clearance in septic shock patients to the perfusion index.…

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Negative / Null Result ReportMedicine

Comparing video-assisted and verbal explanations in Japanese hospital dentistry: patient evaluations in third molar extraction and medical-dental collaborative care.

Matsumoto K, Mitani I, Tsutsui T et al. · 2026 · BMC medical informatics and decision making

Background Video-assisted explanations may support standardized patient information delivery, but their role in hospital dentistry remains insufficiently evaluated. This study aimed to compare patient evaluations of video-assisted and…

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Negative / Null Result ReportOpen accessMedicine

Retinal microvascular alterations in children with amblyopia.

Al-Haddad C, Ibrahim H, Salameh N et al. · 2026 · PloS one

Purpose To investigate and compare retinal vascular changes, including superficial macular vessel density, foveal avascular zone, and the macular perfusion densities, in amblyopic, fellow, and control eyes using optical coherence…

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Negative / Null Result ReportMedicine

Validity of optical coherence tomography angiography in the differential diagnosis of papilledema and pseudopapilledema.

Cerdan-Hernandez E, Palencia-Herranz MJ, Barón M et al. · 2026 · Journal of optometry

Purpose To assess the value of optical coherence tomography angiography (OCTA) peripapillary retinal vascularization in differentiating papilledema from pseudopapilledema. Methods A cross-sectional study, prospective recruitment patients…

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Negative / Null Result ReportMedicine

Influence of X-ray beam angulation on the radiographic detection of implant-abutment interface misfits: A quantitative in vitro analysis.

Terzioglu H, Efeoglu S, Sarikaya CH et al. · 2026 · Journal of prosthodontics : official journal of the American College of Prosthodontists

Purpose This study evaluated the effect of periapical X-ray angulation on the diagnostic accuracy of detecting vertical misfits at the implant-abutment interface using Medentika Microcone dental implants (4.0 mm diameter, 11 mm length;…

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Negative / Null Result ReportOpen accessMedicine

Effects of dietary chitin supplementation on body weight, haematology and serum biochemistry, fecal scores and gut microbiota of captive pangolins.

Wang X, Xie C, Zheng R et al. · 2026 · Animal microbiome

Termites are a natural component of the diet of Malayan pangolins, whereas artificial diets used under captive conditions may differ substantially from wild prey in structure and composition, particularly in chitin content. This study…

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Negative / Null Result ReportOpen accessMedicine

Transspinal direct current stimulation as targeted therapy to increase motor neuron output and restore inhibition in human spinal cord injury.

Sayed Ahmad AM, Knikou M · 2026 · Frontiers in neurology

Introduction In this clinical trial, we evaluated changes in the output of motoneurons and spinal inhibitory mechanisms across multiple spinal segments before and after a series of transspinal direct current stimulation (tsDCS) sessions in…

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Negative / Null Result ReportOpen accessMedicine

Preclinical Analysis of Sex-Specific Differences in the Angiogenic and Inflammatory Tissue Response to Surgical Sutures.

Wrublewsky S, Weigl J, Bickelmann C et al. · 2026 · Journal of functional biomaterials

Surgical sutures are widely used biomaterials in clinical practice. Like all other biomaterials, they induce a foreign body response after implantation that involves inflammation and angiogenesis. Although it is well known that these…

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Negative / Null Result ReportOpen accessMedicine

N95 filtering facepiece respirator fit assessment outcomes by gender, age, race, and facial hair in a community population sample.

Bagheri Hosseinabadi M, Yu M, Petersen A et al. · 2026 · Annals of work exposures and health

The necessity for respiratory protection has increased due to global threats such as pandemics, industrial accidents, and extreme weather events. The effectiveness of N95 filtering facepiece respirators depends on how well they fit the…

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Negative / Null Result ReportMedicine

Comparable survival over an extended follow-up after on-pump versus off-pump coronary artery bypass grafting: a propensity score-matched cohort.

Pikkujämsä A, Rinne P, Wistbacka JO et al. · 2026 · BMC cardiovascular disorders

Background Long-term survival following off-pump coronary artery bypass grafting (OPCAB) compared with conventional on-pump coronary artery bypass grafting (ONCAB) remains uncertain. Randomised trials and meta-analyses up to 5-10 years…

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Negative / Null Result ReportMedicine

Impact of music intervention on endoscopic retrograde cholangiopancreatography patients' pain, anxiety, and vital signs: a randomized controlled trial.

Çakır E, Ciğerci Y, Yılmaz S · 2026 · Scientific reports

This study aimed to evaluate the effects of a music intervention on anxiety, pain, and vital signs in patients undergoing Endoscopic Retrograde Cholangiopancreatography (ERCP). This randomized controlled trial included 70 patients who…

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Negative / Null Result ReportMedicine

Automated Rigo Classification: An Innovative Artificial Intelligence System.

Schmidt N, Johnson G, Nencka A et al. · 2026 · Studies in health technology and informatics

Although there is variation in clinicians' application of the Rigo classification system (RCS) to adolescent idiopathic scoliosis, no artificial intelligence (AI) models have been developed to standardize the RCS specifically. This study…

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Abandoned HypothesisOpen accessMedicine

Emotion regulation skills training for adolescents and parents in a clinical setting: a randomised controlled trial.

Holmqvist Larsson K, Falkenström F, Andersson G et al. · 2026 · Child and adolescent psychiatry and mental health

Background Emotion dysregulation is a transdiagnostic construct associated with psychiatric symptomatology. Improving strategies to regulate emotions is an important focus in several psychological treatments. In the current study we…

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Abandoned HypothesisOpen accessMedicine

Implantation of a Continuous-Flow Left Ventricular Assist Device During Cardiopulmonary Bypass Is Associated with a Significant and Transient Acute Thromboinflammatory Response.

Gerogianni A, Sørensen G, Hoel TN et al. · 2026 · International journal of molecular sciences

Left ventricular assist device (LVAD) implantation is a life-saving therapy for end-stage heart failure but may compromise immune integrity. Mechanical shear stress and surface-induced innate immune activation can trigger bleeding and…

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Negative / Null Result ReportMedicine

Mid-term clinical outcomes of mobile-bearing UKA: a retrospective study on the influence of patellofemoral joint disease, lower limb alignment, and implant positioning.

Chen M, Zhang C, Fan Z et al. · 2026 · BMC musculoskeletal disorders

Background Unicompartmental knee arthroplasty (UKA) has become an effective treatment for medial compartment osteoarthritis of the knee. However, its use in patients who also have patellofemoral joint osteoarthritis (PFOA) before surgery…

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Negative / Null Result ReportOpen accessMedicine

Deficit irrigation and grafting effects on soil attributes, vegetative growth, yield components, and quality of 'Crimson Seedless' grapevines under a semiarid region.

Salama AM, Al-Obeed RS, Helmy A et al. · 2026 · Frontiers in plant science

This study evaluated the combined effects of grafting and deficit irrigation (DI) on soil attributes, vegetative growth, yield components, fruit quality, and water productivity of 'Crimson Seedless' grapevines under semiarid conditions. It…

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Negative / Null Result ReportMedicine

Comparison of the efficacy of posterior lumbar interbody fusion and transforaminal lumbar interbody fusion in the treatment of double-level lumbar spondylolisthesis combined with spinal stenosis: a retrospective comparative study.

Ma Z, Luan H, Abulimiti K et al. · 2026 · BMC surgery

Objective To compare the clinical and radiographic outcomes of posterior lumbar interbody fusion (PLIF) and transforaminal lumbar interbody fusion (TLIF) in the treatment of double-level lumbar spondylolisthesis combined with spinal…

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