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WASTE Journal

Browse the failure-mode index

21,287 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result ReportOpen accessMedicine

Delayed orocecal transit in pediatric gut-brain interaction disorders: A comparative study using the lactulose breath test.

Devanarayana NM, Rajindrajith S, de Silva DGH et al. · 2025 · World journal of gastrointestinal pathophysiology

Background Functional abdominal pain disorders (FAPDs) are common gut-brain interaction disorders with unclear pathophysiology. While impaired gastrointestinal motility is thought to play a key role, small intestinal dysmotility remains…

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Negative / Null Result Report

A population genetic study of Fusarium graminearum , the causal agent of Fusarium Head Blight, provides insights into patterns of inoculum dispersal in wheat fields at a regional scale

Nguyen TBH, Le Floch G, Henri-Sanvoisin A et al. · 2025 · Preprint

ABSTRACT Fusarium graminearum is the primary pathogen responsible for Fusarium Head Blight (FHB) in cereals, causing yield losses and mycotoxin contamination. The present study investigated the genetic diversity and population structure of…

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Negative / Null Result ReportOpen accessMedicine

Non-tobacco nicotine dependence is associated with increased complications following clavicle open reduction internal fixation.

Adio AA, Goyal RK, Skiena A et al. · 2026 · Archives of orthopaedic and trauma surgery

Background Tobacco dependence is well established to impair bone healing and increase postoperative complications. However, the independent effects of nicotine, separate from combustion-related factors, remain unclear. This study aimed to…

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Abandoned HypothesisMedicine

[Clinical and genetic characteristics of infantile-onset Pompe disease​ and long-term efficacy of enzyme replacement therapy].

Sun YM, Wang YJ, Wang HF et al. · 2026 · Zhonghua er ke za zhi = Chinese journal of pediatrics

Objective: To analyze the clinical and genetic characteristics of infantile-onset Pompe disease (IOPD) and evaluate the long-term efficacy of enzyme replacement therapy (ERT). Methods: A retrospective cohort study was conducted on 24 IOPD…

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Negative / Null Result Report

Exploration of shift work among nursing professionals related to interconnected determinants of health in a hospital: a cross-sectional study

Rubiño-Díaz JÁ, Ferrández-Sempere S, Canellas F et al. · 2026 · Preprint

Abstract Aim To assess sleep quality and its relationship with interconnected health variables among nursing professionals working shifts. Methods A cross-sectional descriptive observational study. A total of 247 nursing professionals…

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Negative / Null Result ReportOpen accessMedicine

Effects of Defatted Black Soldier Fly (<i>Hermetia illucens</i>) Meal on the Performance, Digestibility and Blood Parameters of Weaned Piglets.

Parreiras M, Pinheiro V, Moreira O et al. · 2026 · Animals : an open access journal from MDPI

This study investigated the effects of different inclusion levels of defatted black soldier fly ( Hermetia illucens : BSF) larval meal on growth performance, haematological and biochemical blood parameters, and nutrient digestibility in…

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Negative / Null Result ReportOpen accessMedicine

Effect of different feed particle size on digestive tract morphology, digesta viscosity, nutrient retention, and blood biochemical parameters in slow-growing broiler chickens.

Novotný J, Čumplík L, Horáková L et al. · 2026 · Veterinary and animal science

The study evaluated the effect of feed particle size on health and performance indicators in slow-growing broiler chickens. Performance traits, digestive tract morphology, digesta viscosity, nutrient retention, and blood biochemical…

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Negative / Null Result ReportOpen accessMedicine

Culture medium influences detectability of antimicrobial effects of autologous platelet concentrates against anaerobic periodontal pathogens.

Jansen EE, Braun A, Jansen P et al. · 2026 · BMC oral health

Background Autologous platelet concentrates (PRP, PRF, i-PRF) represent blood-derived biomaterials that have been reported to exhibit antimicrobial activity against oral microorganisms in vitro. In diffusion-based assays, visualization of…

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Negative / Null Result ReportMedicine

Effects of lower limb joint manipulation on squat strength and ankle range of motion: a sham-controlled double-blind randomised cross-over trial.

Morley-Hart R, Losco B, Dempsey AR et al. · 2026 · Chiropractic & manual therapies

Background The back squat is a commonly prescribed exercise for developing lower body strength. The ability to squat can be affected by reduced ankle dorsiflexion range of motion (DF-ROM), leading to limited squat depth and dysfunctional…

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Replication FailureMedicine

BDNF rs6265 polymorphism is not associated with the occurrence of overactive bladder and its response to intradetrusor injection of botulinum neurotoxin type A in female patients.

Ciećwież SM, Lewandowska K, Boroń A et al. · 2026 · Scientific reports

Reports suggest increased urinary excretion of Brain-Derived Neurotrophic Factor in patients with Overactive Bladder (OAB). The rs6265 (c.196G > A, p.Val66Met) polymorphism in the BDNF gene was previously associated with impaired secretion…

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Negative / Null Result ReportOpen accessMedicine

Cerebroplacental Ratio in Monochorionic Diamniotic Twin Pregnancies with and Without Gestational Diabetes: A Longitudinal Cohort Study.

Yerlikaya-Schatten G, Adamovic M, Catic A et al. · 2026 · Journal of clinical medicine

Objective: To investigate whether gestational diabetes mellitus (GDM), including insulin-treated GDM, affects cerebroplacental ratio (CPR) values in monochorionic diamniotic (MCDA) twin pregnancies. Methods: This retrospective…

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Negative / Null Result ReportMedicine

Assessment of mandibular ramus dimensions in relation to lower third molar impaction in class II malocclusion: a comparative 2D and 3D CBCT evaluation.

AbuHarb H, Abusafia B, Fu X et al. · 2026 · BMC oral health

Background To assess the relationship between mandibular ramus morphology and lower third molar impaction among patients with Class II malocclusion using CBCT. Methods A retrospective study included 536 patients with Class II malocclusion,…

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Negative / Null Result ReportMedicine

Exploratory Study of Radiation Exposure between Image Intensifier-Equipped C-Arm and a Flat Panel Detector During Volar Plate Fixation of the Distal Radius.

Honda Y, Kaida E, Miyazaki Y et al. · 2026 · The journal of hand surgery Asian-Pacific volume

Background: To compare the amount of radiation exposure received by the surgeon during volar locking plate fixation for distal radius fractures using an image intensifier (II) and a flat panel detector (FPD). Methods: We included 40…

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Negative / Null Result ReportOpen accessMedicine

Evaluation of the effects of different irrigation activation techniques on the surface roughness of dentin and blood clot in regenerative endodontic models.

Bulak Yeliz S, Uğur Aydın Z · 2026 · Lasers in medical science

Regenerative endodontic treatment (RET) is a biologically based approach aiming to restore the pulp-dentin complex in immature permanent teeth with necrotic pulps. In this procedure, a blood clot is induced within the canal to serve as a…

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Negative / Null Result ReportOpen accessMedicine

Clinical Status and Salivary aMMP-8 Evaluation of 0.12% Chlorhexidine Versus MicroRepair<sup>®</sup> ABX Mouthwash in the Non-Surgical Management of Plaque-Induced Gingivitis: A Randomized Controlled Trial.

Scribante A, Pascadopoli M, Pellegrini M et al. · 2026 · Dentistry journal

Objectives : To compare the adjunctive efficacy of a MicroRepair ® mouthwash containing an antibacterial complex (ABX), composed of cetylpyridinium chloride, magnolol, and honokiol, with 0.12% chlorhexidine (CHX) in the management of…

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Negative / Null Result ReportOpen accessMedicine

Safety of flexible bronchoscopy in elderly patients.

Spiegel S, Hübner RH, Schürmann D et al. · 2026 · BMC pulmonary medicine

Background Flexible bronchoscopy is an indispensable tool in respiratory medicine. In the context of an aging society and increasing life expectancy, the number of elderly, often multimorbid patients is growing. This raises important…

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