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Browse the failure-mode index

21,707 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Non-significant Effect of El Niño on the Nest Occupancy and Breeding Success of Markham’s Storm Petrel <i>Hydrobates markhami</i>

Fernando Medrano, Benjamín Gallardo, Pablo Gutiérrez et al. · 2024 · Marine Ornithology

The impact of the El Niño varies across seabirds, usually altering the distribution and causing population declines. Understanding El Niño’s effects is thus critical for conservation. We monitored 296 nests of the little-known Hydrobates…

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Negative / Null Result ReportOpen access

Correlation of c-erbb2 Expression in Undifferentiated Nasopharyngeal Carcinoma and Tumor Size (T-Stage) (Dyah Fauziah et al.) 290 CORRELATION OF C-ERBB2 EXPRESSION IN UNDIFFERENTIATED NASOPHARYNGEAL CARCINOMA AND TUMOR SIZE (T-STAGE), REGIONAL LYMPHNODES

Willy Sandhika, Faroek Hoesin, Dyah Fauziah · 2020

No significant correlation was found between c-erbB2 expression and tumor size (T-stage). c-erbB2 expression in various N-stages were as follows: N0 (80%), N1 (33,3%), N2 (50%), N3 (42,9%). No significant correlation was found between…

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Negative / Null Result ReportOpen access

有酸素運動 (Aerobics) を中心にした一般教養体育実技の有効性と限界について-第一報:血液組成と体組成におよぼす影響-

田原, 靖昭, 西澤, 昭, 管原, 正志 et al. · 1991

Aerobic exercise class was opened and blood and physical composition were examined. Results indicated that no significant improvement on measured items was observed. Frequency of participation is suggested to be increased or class goal…

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Negative / Null Result ReportOpen access

Performance of Perforated Heat Exchanger Surfaces

J. R. Mondt, D. C. Siegla · 1974

Heat transfer and flow friction behavior have been measured for plain and perforated plate-fin and 10-deg herringbone surfaces. For the range of geometries and Reynolds numbers studied, the perforations produced no significant improvement…

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Negative / Null Result ReportOpen access

Treatment outcomes of different prognostic groups of patients on cancer and leukemia group B trial 39801: induction chemotherapy followed by chemoradiotherapy compared with chemoradiotherapy alone for unresectable stage III non-small cell lung cancer

Akerley, Wallace, Herndon, James E. 2nd, Vokes, Everett E. et al. · 2017

BACKGROUND: In Cancer and Leukemia Group B 39801, we evaluated whether induction chemotherapy before concurrent chemoradiotherapy would result in improved survival and demonstrated no significant benefit from the addition of induction…

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Negative / Null Result ReportOpen access

Treatment Outcomes of Different Prognostic Groups of Patients on Cancer and Leukemia Group B Trial 39801: Induction Chemotherapy Followed by Chemoradiotherapy Compared with Chemoradiotherapy Alone for Unresectable Stage III Non-small Cell Lung Cancer

Akerley, Wallace, Vokes, Everett E., Cicchetti, M Giulia et al. · 2009

BackgroundIn Cancer and Leukemia Group B 39801, we evaluated whether induction chemotherapy before concurrent chemoradiotherapy would result in improved survival and demonstrated no significant benefit from the addition of induction…

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Negative / Null Result ReportOpen access

IL-24 regulated CXCR4 at post-transcriptional level.

Jiankang Jin (703171), Stephen J. Archibald (703175), Janani Panneerselvam (703170) et al. · 2015

A , RT-PCR analysis showed IL-24 reduced CXCR4 mRNA levels at 6 h and 24 h ( P B , CXCR4 promoter activity was determined using a luciferase reporter vector. Induction of IL-24 showed no significant reduction in luciferase activity…

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Negative / Null Result ReportOpen access

Effects of α-MSH treatment on Caspase 3 activity.

Andrew W. Taylor (451751) · 2013

The macrophages lysates were assayed for protein concentration and Caspase 3 activity. There was no significant change of Caspase 3 activity in cells treated with α-MSH compared to SFM cells. The graft is the mean ± SD of Caspase 3…

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Negative / Null Result ReportOpen access

Water radial arm maze performance.

Tristan G. Pesaresi (6751925), Grayson Breneman Ashby (6751931), Min-Ken Liao (6751934) et al. · 2019

Working memory correct (A), working memory incorrect (B) and reference memory (C) errors over the 12 days of testing are shown between low fat and high fat-fed rats. There were no significant differences between dietary group for any of…

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Negative / Null Result ReportOpen access

Birth Order and past-Orientation

Christopher D. Green, Gladys M. Batten, Anton F. De Man et al. · 1983

Three studies examined Adler's suggestion that firstborns are past-oriented. The first study of the relationship between birthorder and temporal relatedness and dominance in 37 female undergraduates yielded no significant differences. The…

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Negative / Null Result ReportOpen access

A. Box plot of the maximum decrease of temperatures from the baseline.

Ayako Asakura (711890), Takahisa Goto (711892), Takahiro Mihara (789554) · 2015

No significant differences were detected among the groups, but the maximum decreases tended to be smaller in the CHO and ORS groups than in the control group. B. Box plot of the final temperature changes at the end of surgery. No…

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Negative / Null Result ReportOpen access

Conflict duration on the flanker task (i.e., reaction time for each incongruent trial–reaction time for each congruent trial) pre- (white bar) and post-treatment (black bar) with OT or placebo.

Yuko Yoshimura (283970), Hirotoshi Hiraishi (283977), Mitsuru Kikuchi (140272) et al. · 2015

Two-way ANOVA (treatment × drug) failed to demonstrate any drug or treatment effects, and no significant interaction between these two factors was detected. Therefore, we failed to demonstrate any OT-related effect on…

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Negative / Null Result ReportOpen access

Cutaneous sterile pyogranuloma/granuloma syndrome in a dog

SPATERNA, Andrea, MECHELLI A., SANTORO D. et al. · 2008

A case of canine cutaneous sterile pyogranuloma/granuloma syndrome (SPGS) with generalized asymmetrical alopecia and plaques is described. Results from histopathologic examination were suggestive of SPGS and failed to demonstrate any…

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Negative / Null Result ReportOpen access

Visual impairment, aging and driving ability

Wood, Joanne M. · 2002

It has been suggested that over 90% of the sensory information for driving is visual. Despite this belief, traditional studies have failed to demonstrate that increased crash rates arise from impaired vision. However, more recent studies…

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Replication FailureOpen access

Heritability of the Carabelli Cusp in Twins

Robert H. Biggerstaff · 1973

The study of the Carabelli trait among 199 monozygotic and dizygotic twin pairs failed to demonstrate a high degree of heritability. Analyses of antimere differences in individuals indicated a lack of mirroring and no sexual dimorphism.…

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Negative / Null Result ReportOpen access

A pilot, double blind randomised controlled trial of prednisolone for women with recurrent miscarriage and raised uterine natural killer cell density [Abstract]

Dawood, Feroza, Farquharson, Roy G., Turner, M. A. et al. · 2011

Introduction: Multiple trials of immunotherapy for reproductive failure have failed to demonstrate significant benefit. A reason for this may be the lack of a test that selects which women will benefit from treatment. High density of…

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Negative / Null Result ReportOpen access

Good laboratory practice: preventing introduction of bias at the bench

Macleod, Malcolm R.; id_orcid, Donnan, Geoffrey A., Traystman, RJ et al. · 2009

Background and Purpose—As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review—Accumulating…

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