21,257 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Heinemann FM, Hallensleben M, Althaus K et al. · 2026 · HLA
Single antigen (SA) tests are indispensable for an accurate HLA antibody identification in sera of transplant patients. Three commercial tests using purified single antigens combined with microbead or microarray technology are currently…
View details →Zheng J, Wu M, Wang X et al. · 2026 · Cells
Prime editing (PE) is a precise genome-editing technology that avoids double-strand breaks, holding great promise for clinical and agricultural applications. However, its genome-wide off-target effects are not fully understood, raising…
View details →Lindell H, Lehtilä K, Dinnétz P · 2026 · Preprint
Abstract Background Wild boar ( Sus scrofa ) have expanded in northern Europe, yet their role in the ecology of tick-borne pathogens remains poorly understood. This study investigated the occurrence of Anaplasma phagocytophilum and…
View details →Stoff R, Routman DM, Yalon M et al. · 2026 · Therapeutic advances in medical oncology
Background Circulating tumor DNA (ctDNA) is predictive of recurrence in resected stage III melanoma, yet its role in the neoadjuvant setting for clinical stage III (cSIII) is unclear. Objective Assess the association between ctDNA and…
View details →Chu NH, Le HD, Quach NT et al. · 2026 · Biochemical genetics
The optical purity of lactic acid is a critical parameter for producing high-performance polylactic acid (PLA). To investigate the genetic basis of stereospecific lactic acid biosynthesis, the present study aimed to functionally…
View details →Sulaiman AR, Bassit GE · 2026 · BMC oral health
Background Primary Hyperoxaluria Type 1 (PH1) is a rare metabolic disorder characterized by systemic oxalate deposition, which may influence bone metabolism through mechanisms such as oxalate accumulation in alveolar bone, renal…
View details →Lu J, Ahmad A, Chomont N et al. · 2026 · Frontiers in immunology
Due to persistent immune dysfunction, People with HIV (PWH) are at increased risk of more severe infections with SARS-CoV-2 and hospitalizations. In several countries, they were listed as a priority group for receiving anti-SARS-CoV-2…
View details →Noey JD, Kearfott KJ · 2026 · Health physics
This study examines the range of methodologies used to determine the minimum detectable dose for LiF:Mg,Ti thermoluminescent dosimeters, emphasizing the importance of incorporating uncertainties when assessing variability in dosimeter…
View details →Kanamaru K, Sakai A, Kobayashi T et al. · 2026 · Clinical journal of gastroenterology
We present a rare case of autoimmune pancreatitis (AIP) confined exclusively to the subepithelial layer in the main pancreatic duct (MPD) without associated pancreatic enlargement or mass formation. A 73-year-old man presented with…
View details →Metwally NKA, de Boer F, Vreeken J et al. · 2025 · Scientific reports
This study compared three multiplex immunoassay platforms, Meso Scale Discovery (MSD), NULISA, and Olink, for detecting protein markers in stratum corneum tape strips, a non-invasive sampling method challenged by low protein yield. We…
View details →Karlina Y, Rizaldy D, Riani C et al. · 2026 · Iranian journal of microbiology
Background and objectives Enzymes are protein biomolecules that act as catalysts, including cellulase and β-glucosidase with extensive applications. Thus, this work aimed to contrast the activity of both enzymes from tempeh fermented by…
View details →Shfare MT, Kahsay H, Gebrehiwot GT et al. · 2026 · Infectious agents and cancer
Background Worldwide, it is believed that high-risk human papillomavirus (hr-HPV) strains are the root cause of many types of cancers, including cervical cancer, anorectal cancers, vaginal cancers, and penile cancers, with an estimated…
View details →Moschese D, Fusetti C, Lazzarin S et al. · 2026 · Antimicrobial agents and chemotherapy
To address the lack of data on male genital tract penetration of CAB-LA PrEP, seminal plasma was collected at days 3, 7, 28, 84, and 140 and analyzed by LC-MS/MS. CAB was detectable in 71% of samples at day 3, 73% at day 7, and 92% at day…
View details →Agergaard K, Thiesson HC, Carstens J et al. · 2026 · Therapeutic drug monitoring
Background Emerging strategies for tacrolimus dose optimization in kidney transplant recipients include measuring drug concentrations in peripheral blood mononuclear cells (PBMCs) and biomarkers of immunosuppression, such as torque teno…
View details →Atila C, Murugesu R, Rudin D et al. · 2026 · Pituitary
PURPOSE: Oxytocin (OXT) plays key roles in social behaviour, stress regulation, and reproductive physiology. OXT deficiency has been described in pituitary disorders and is associated with increased anxiety and impaired prosocial…
View details →Schneider F, Conze T, Büttner K et al. · 2026 · Veterinary sciences
The provision of high-quality colostrum immediately after birth is essential to ensure adequate passive transfer of immunity in neonatal calves. This study evaluated colostrum viscosity as a potential indicator of colostrum quality, its…
View details →Perrin A, Deillon C, Christe P et al. · 2026 · Parasites & vectors
Arthropod-borne viruses are increasingly reported across Europe, with Culex pipiens serving as the main vector of West Nile and Usutu viruses. The C. pipiens complex comprises two ecologically distinct ecotypes, pipiens and molestus, which…
View details →Lee S, Leiserowitz A, Briggs L et al. · 2026 · Preprint
News media shape public perceptions of issue importance, yet the position of climate change within the broader media landscape over time remains poorly understood. We conducted a large-scale content analysis of 6.4 million articles…
View details →Guo Y, Jiang B, Chen H et al. · 2026 · Aquaculture.
Bdellovibrio is a kind of fast-moving bacteria that mainly preys on Gram-negative bacteria. Aeromonas hydrophila is one of the most common pathogenic bacteria for many animals. However, the potential application of freshwater-derived…
View details →Sanyal RP, Prashar V, Sunkar R et al. · 2026 · The Biochemical journal
Superoxide dismutases (SODs) are involved in cellular reactive oxygen species (ROS) homeostasis under diverse conditions. Among different plant SODs, CuZnSODs (CSDs) are most abundant and localized to multiple compartments, including…
View details →Radmer S, Andresen JR · 2026 · Journal of surgical case reports
Scapular winging is an uncommon but clinically important sign that is often initially attributed to local shoulder pathology or isolated peripheral nerve injury. We report two patients with exertional scapular winging caused by different…
View details →de la Colina AN, Skaperda Z, Charisis S et al. · 2026 · Preprint
Peripheral blood measurements dominate oxidative stress research, yet whether they reflect central nervous system (CNS) redox status remains untested in humans. We simultaneously profiled five biomarkers, total antioxidant capacity (TAC),…
View details →Turkmen D, Ucuz I, Altunisik N et al. · 2026 · Cutaneous and ocular toxicology
Objective This exploratory study aimed to evaluate the basic temperament and behavioral characteristics of preschool children diagnosed with vitiligo, alopecia areata (AA), and psoriasis, and to compare them with healthy controls.…
View details →Zhakypbek Y, Toktar M, Kossalbayev BD et al. · 2026 · Biology
Dryland soils of the Caspian region of western Kazakhstan are exposed to environmental stress, including drought, alkalinity, low soil organic matter content, and anthropogenic pressure. In this preliminary study, bacterial communities…
View details →Shen Y, Li HX, Dai J et al. · 2026 · Journal of affective disorders
Background Light therapy (LT) may improve sleep and affective disorders in Parkinson's disease (PD), but effects of different intensities and underlying mechanisms remain unclear. Methods Thirty-three patients with PD were randomized to…
View details →Khalid A, Yasir Ali M, Tul Janat R et al. · 2026 · Pakistan journal of pharmaceutical sciences
Background Sorafenib (SB) is a receptor tyrosine kinase inhibitor, currently marketed as an oral dosage form. However, due to severe irritation of the gastrointestinal tract, the drug is facing decreased acceptability as a therapeutic…
View details →Ma Q, Chen K, Wang C et al. · 2026 · PsyCh journal
Previous studies have indicated impaired motor sequence learning in people who stutter (PWS). The present study demonstrates that PWS retain intact sequence learning abilities when motor demands are minimized.
View details →Vockert KL, Winter N, Kirschmann FS et al. · 2026 · Neurological research and practice
Background and aims Hereditary polyneuropathies are rare heterogeneous neurological disorders that cause progressive muscle weakness and disability. As new therapies emerge, sensitive imaging biomarkers to monitor disease progression are…
View details →Johnson L, Chen ZZ, Marshall JG · 2026 · Analytical biochemistry
The detection of human IgG (hIgG) in tris buffer versus fetal calf serum (FCS) served as a model system to explore the factors that contribute to sensitivity of enzyme-linked immunosorbent assay (ELISA) with and without capture reagents.…
View details →Cui H, Wu M, Zhao P · 2026 · Preprint
Abstract Background Myocarditis is a clinically heterogeneous cardiovascular condition that may progress rapidly to severe outcomes, making early recognition and accurate public understanding essential. With the rapid expansion of…
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