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Replication Failure

Significant association of RANKL polymorphisms with bone metastasis among patients with breast cancer

Haoyu Lian; Siyuan Zhou; Huanyang He; Qian Liu; Jinmin Zhao · 2026 · Frontiers in Oncology

WASTE classifies this as Replication Failure · AI classification, approximate

A previously reported effect did not replicate here — verify it holds before you build on it.

Abstract (excerpt)

Objective The purpose of this study was to reveal the genetic correlation of RANKL polymorphisms with bone metastasis in breast cancer patients. Methods In this study, 139 bone metastasis patients and 152 no metastasis were included as the…

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Metadata source: Crossref · DOI 10.3389/fonc.2026.1788455