e-ISSN: Pending

Browse the failure-mode index

21,247 real negative results, null findings, and replication failures. Search the index →

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.

Negative / Null Result Report

Significant effect of information placebo on exercise test results in children with normal weight, overweight and obesity

Shira Fanti‐Oren, Daphna Birenbaum‐Carmeli, Dan Nemet et al. · 2019 · Acta Paediatrica

Abstract Aim The aim of the study was to examine the effect of information placebo on fitness test results in normal weight, overweight and obese children. Methods Twenty‐four pre‐pubertal children with overweight or obesity and 24 age and…

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Negative / Null Result Report

Molecular phylogeny of Echinodera and Ruteria (Coleoptera:Curculionidae:Cryptorhynchinae) and the parallel speciation of Canary Island weevils along replicate environmental gradients

Jonas J. Astrin, Peter E. Stüben · 2010 · Invertebrate Systematics

A molecular phylogeny for the western Palaearctic weevil genus Echinodera Wollaston, 1863 and the former genus Ruteria Roudier, 1954 is presented, combining two mitochondrial genes (CO1 and 16S) in a Bayesian analysis. Special…

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Negative / Null Result Report

No Significant Difference in Cognitive Decline and Mortality between Parkinson’s Disease Dementia and Dementia with Lewy Bodies: Naturalistic Longitudinal Data from the Swedish Dementia Registry

Seyed-Mohammad Fereshtehnejad, Johan Lökk, Anders Wimo et al. · 2018 · Journal of Parkinson’s Disease

Background: Whether dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD) are distinct disorders or two subtypes of the same entity, is not yet fully understood. There is a dearth of knowledge on differences in…

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Negative / Null Result Report

Flow Cytometry Method Analysis of Apoptosis

Xiao-yan Xu, Xiao-cui Nie, Hai-ying Ma et al. · 2014 · Technology in Cancer Research & Treatment

Flow cytometry method (FCM) is a generally accepted tool to analyze apoptosis. Although apoptosis assay kit was applied by many companies, the manufacturers were not consistent with whether using Trypsin with EDTA to collect the adherent…

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Negative / Null Result Report

Inflation in 2022 did not affect congressional voting, but abortion did

Diana C. Mutz, Edward D. Mansfield · 2024 · Proceedings of the National Academy of Sciences

This study examines voting in the 2022 United States congressional elections, contests that were widely expected to produce a sizable defeat for Democratic candidates for largely economic reasons. Based on a representative national…

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Negative / Null Result Report

Significant Prognostic Factors Influencing the Survival Difference of Oral Tongue Squamous Cell Carcinoma

Sarinya Boonpoapichart, Pattama Punyavong, Kamonwan Jenwitheesuk et al. · 2021 · Plastic and Reconstructive Surgery - Global Open

Background: Oral tongue squamous cell carcinoma is the most common malignancy in the oral cavity. Overall survival varies across many countries, and poor prognosis is prevalent in developing countries, including Thailand. Our study aimed…

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Negative / Null Result Report

Biologically relevant small variations of intra-cellular pH can have significant effect on stability of protein–DNA complexes, including the nucleosome

Alexey V. Onufriev · 2023 · Frontiers in Molecular Biosciences

Stability of a protein-ligand complex may be sensitive to pH of its environment. Here we explore, computationally, stability of a set of protein-nucleic acid complexes using fundamental thermodynamic linkage relationship. The nucleosome,…

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Negative / Null Result Report

Effect of Significant Postoperative Complications on Decision Regret After Laparoscopic Sleeve Gastrectomy: a Case–Control Study

Katarzyna Bartosiak, Michał R. Janik, Maciej Walędziak et al. · 2022 · Obesity Surgery

Abstract Background Thus far, no data are available on decision regret about sleeve gastrectomy (SG), particularly in patients who experienced perioperative complications. This study aimed to assess whether patients with postoperative…

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Negative / Null Result Report

Significant sex difference in the association between C‐reactive protein concentration and anthropometry among 13‐ to 19‐year olds, but not 6‐ to 12‐year olds in Nepal

Shoko Konishi, Rajendra Prasad Parajuli, Erica Takane et al. · 2014 · American Journal of Physical Anthropology

ABSTRACT Life history theory predicts a trade‐off between immunostimulation and growth. Using a cross‐sectional study design, this study aims to test the hypothesis that C‐reactive protein (CRP) is negatively associated with height‐for‐age…

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Negative / Null Result Report

Subclinical Systemic Sclerosis Primary Heart Involvement by Cardiovascular Magnetic Resonance Shows No Significant Interval Change

Raluca B. Dumitru, Lesley‐Anne Bissell, Bara Erhayiem et al. · 2023 · ACR Open Rheumatology

Objective Subclinical systemic sclerosis (SSc) primary heart involvement is commonly described. Whether these findings progress over time is not clear. The study aimed to investigate cardiovascular magnetic resonance (CMR) interval change…

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Negative / Null Result Report

Association of oral contraceptive and metformin did not improve insulin resistance in women with polycystic ovary syndrome

Margareth Chiharu Iwata, Livia Porquere, Isabel C. Espósito Sorpreso et al. · 2015 · Revista da Associação Médica Brasileira

Summary Objective: Objective: to compare clinical and laboratory parameters in women with polycystic ovary syndrome (PCOS) using metformin or combined oral contraceptive (COC) after 6 months. Methods: retrospective study analyzing records…

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Negative / Null Result Report

Evening Caffeine Did Not Improve 100-m Swimming Time Trials Performed 60 Min Post-Ingestion or the Next Morning After Sleep

Josh W. Newbury, Bryan Saunders, Lewis A. Gough · 2022 · International Journal of Sport Nutrition and Exercise Metabolism

The potential ergogenic benefits of caffeine (CAF) are well known within the athletic community, often leading to its use in adolescent swimming cohorts to enhance their performance. However, it has previously been reported that CAF has…

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Negative / Null Result Report

Posttraumatic growth during cognitive behavioural therapy for posttraumatic stress disorder: Relationship to symptom change and introduction of significant other assessment

Christine F. Schubert, Ulrike Schmidt, Hannah Comtesse et al. · 2019 · Stress and Health

Abstract Posttraumatic growth (PTG) may play a role in the treatment of posttraumatic stress disorder (PTSD) as it is supposed to have either beneficial or dysfunctional effects on treatment‐related PTS symptom (PTSS) changes. This study…

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Negative / Null Result Report

Clinical Decision Support System with Renal Dose Adjustment Did Not Improve Subsequent Renal and Hepatic Function among Inpatients: The Japan Adverse Drug Event Study

Ryuhei Wada, Jiro Takeuchi, Tsukasa Nakamura et al. · 2020 · Applied Clinical Informatics

Abstract Background Medication dose adjustment is crucial for patients with renal dysfunction (RD). The assessment of renal function is generally mandatory; however, the renal function may change during the hospital stay and the manual…

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Negative / Null Result Report

CURING HEPATITIS C WITH THE NEW DIRECT ACTING ANTIVIRALS DID NOT IMPROVE INSULIN RESISTANCE AFTER ONE YEAR

Lohanna STRAUHS-NITSCH, Marcela Ferro CAMPIOLO, Daphne Benatti Gonçalves MORSOLETTO et al. · 2020 · Arquivos de Gastroenterologia

ABSTRACT BACKGROUND: Chronic hepatitis C still figures as an important cause of morbidity among the Brazilian population, and is closely associated with metabolic disturbances, including insulin resistance (IR), which can be evaluated by…

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