COSMIN review of the PANSS Marder factor solution and other factor models in people with schizophrenia
Maximilian Roithmeier; Simon Geck; Markus Bühner; Sophia Wehr; Lucia Weigel; Josef Priller; John M. Davis; Stefan Leucht · 2025 · Schizophrenia
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract The Positive and Negative Syndrome Scale (PANSS) is widely used to assess schizophrenia symptoms. Initially designed with three subscales, Marder et al.´s 5-factor-Model (M5M) first proposed in 1997 has been frequently used in treatment trials, but it has never been systematically reviewed for its measurement properties. We utilized the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) guideline for systematic reviews and meta-analytical procedures to assess the psychometric properties of the M5M-PANSS. COSMIN comprises several steps: literature se
Abstract by Maximilian Roithmeier; Simon Geck; Markus Bühner; Sophia Wehr; Lucia Weigel; Josef Priller; John M. Davis; Stefan Leucht, Schizophrenia (2025) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1038/s41537-025-00600-6