Negative / Null Result ReportPsychology
Emiko J. Muraki, Penny M. Pexman · 2021 · Journal of Experimental Psychology Learning Memory and Cognition
In embodied theories of semantic representation, the processes and mechanisms of modal simulations that are engaged during semantic processing have tended to be underspecified. We investigated the possibility that motor imagery may be a…
View details →Negative / Null Result ReportOpen accessDecision Sciences
J. van Wolferen, Yoel Inbar, Marcel Zeelenberg · 2013 · Judgment and Decision Making
Abstract In this paper we test two hypotheses regarding magical thinking about the perceived likelihood of future events. The first is that people believe that those who “tempt fate” by failing to take necessary precautions are more likely to suffer negative outcomes. The second is the “protection effect”, where reminding people of precautions they have taken leads them to see related risks as less likely. To this end, we describe the results from three attempted direct replications of a protection effect experiment reported in Tykocinski (2008) and two replications of a tempting fate experime
View details →Negative / Null Result ReportOpen accessSocial Sciences
Cristian Vasco · 2013 · Americanae (AECID Library)
Con datos de la “Encuesta de condiciones de vida (ecv) 2005-2006”, este artículo analiza el impacto de la migración internacional y las remesas en la iniciativa emprendedora en el Ecuador rural. Los resultados sugieren que ni la migración…
View details →Negative / Null Result ReportOpen accessNeuroscience
Ellen Bialystok · 2020 · Journal of Multilingual Theories and Practices
The controversy over whether bilingualism has consequences for mind and brain shows no sign of abating. A steady stream of research reporting both positive results supporting the claim for beneficial effects of bilingualism and null…
View details →Negative / Null Result ReportOpen accessEngineering
Seong Ki Yoo, Simon L. Cotton, Young Jin Chun et al. · 2017 · IEEE Antennas and Wireless Propagation Letters
This letter investigates the first-order characteristics of dynamic off-body communications channels at 60 GHz. In particular, we have studied signal propagation from a chest-worn millimeter-wave transmitter as an adult male walked toward and then away from a hypothetical base station. The mobile line-of-sight (LOS) and non-LOS (NLOS) channel measurements have been conducted in a diverse range of environments, including a hallway, an open office, an anechoic chamber, and an outdoor car park. In this study, we have decomposed the received signal into its path loss, large-scale, and small-scale
View details →Negative / Null Result ReportSocial Sciences
Lukas Klaschinski, Konrad Schnabel, Michela Schröder–Abé · 2017 · Comprehensive Results in Social Psychology
The current study attempted to replicate results by Cuddy, Wilmuth, Yap, and Carney (2015) who showed that adopting high-power poses prior to a demanding job interview improved dominant behavior and overall hireability judgments. We…
View details →Negative / Null Result ReportMedicine
Amy K. Sheaffer, Min S. Lee, Dennis Hernandez et al. · 2011 · Antiviral Therapy
BACKGROUND: To support clinical development of HCV non-structural protein (NS) 3 protease inhibitors (PIs), phenotypic monitoring of patient isolates is a prerequisite for understanding the emergence of resistance. HCV isolates typically…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Stephanie Loomis, Man Li, Nisa M. Maruthur et al. · 2018 · Diabetes
Fructosamine and glycated albumin are potentially useful alternatives to hemoglobin A1c (HbA1c) as diabetes biomarkers. The genetic determinants of fructosamine and glycated albumin, however, are unknown. We performed genome-wide…
View details →Negative / Null Result ReportPsychology
Shayne B. Piasta, Jessica A. R. Logan, Cynthia M. Zettler‐Greeley et al. · 2022 · Journal of Learning Disabilities
Preschool-age children identified as at risk for later reading difficulties can benefit from supplemental, small-group emergent literacy intervention. As such interventions become commercially available and marketed to preschool programs,…
View details →Negative / Null Result ReportOpen accessNeuroscience
Megan Willis, Andrea I. Costantino, Michael A. Nitsche et al. · 2019 · Frontiers in Neuroscience
There has been increasing interest in the utility of transcranial electrical stimulation as a tool to enhance cognitive abilities. In the domain of face perception, enhancements have been reported for both transcranial direct current stimulation (tDCS) and high-frequency transcranial random noise stimulation (tRNS) targeting the occipitotemporal cortex. In a series of two experiments, we attempted to replicate these findings for face identity perception, and extend on previous studies, to determine if similar enhancements are also observed for object and facial expression perception. In Experi
View details →Negative / Null Result ReportOpen accessMedicine
Victor Virlogeux, Rebecca E. Graff, Thomas J. Hoffmann et al. · 2015 · Cancer Epidemiology Biomarkers & Prevention
BACKGROUND: Prostate cancer incidence and mortality rates vary across populations, with African American men exhibiting the highest rates. To date, genome-wide association studies have identified 104 SNPs independently associated with…
View details →Negative / Null Result ReportOpen accessMedicine
Lei Sun, Sergey Yagoda, Baiyun Yao et al. · 2019 · Clinical Drug Investigation
BACKGROUND AND OBJECTIVE: Olanzapine is an atypical antipsychotic indicated for the treatment of schizophrenia and, either as monotherapy or as an adjunct to lithium or valproate, for bipolar I disorder. Multiple daily doses of olanzapine…
View details →Negative / Null Result ReportOpen accessMedicine
Tamar Sofer, Leslie S. Emery, Deepti Jain et al. · 2019 · Scientific Reports
Abstract Lower extremity peripheral artery disease (PAD) burden differs by race/ethnicity. Although familial aggregation and heritability studies suggest a genetic basis, little is known about the genetic susceptibility to PAD, especially in non-European descent populations. Genome-wide association studies (GWAS) of the ankle brachial index (ABI) and PAD (defined as an ABI < 0.90) have not been conducted in Hispanics/Latinos. We performed a GWAS of PAD and the ABI in 7,589 participants aged >45 years from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). We also performed
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Fabio Caraffini, Giovanni Iacca · 2020 · Mathematics
We present Stochastic Optimisation Software (SOS), a Java platform facilitating the algorithmic design process and the evaluation of metaheuristic optimisation algorithms. SOS reduces the burden of coding miscellaneous methods for dealing…
View details →Negative / Null Result ReportOpen accessMedicine
Arran T. Reader, Victoria S. Trifonova, H. Henrik Ehrsson · 2021 · European Journal of Neuroscience
Body ownership refers to the distinct sensation that our observed body belongs to us, which is believed to stem from multisensory integration. This is commonly shown through the rubber hand illusion (RHI), which induces a sense of ownership over a false limb. Whilst the RHI may interfere with object-directed action and alter motor cortical activity, it is not yet clear whether a sense of ownership over an artificial hand has functional consequences for movement production per se. As such, we performed two motion-tracking experiments (n = 117) to examine the effects of the RHI on the reaction t
View details →Negative / Null Result ReportPharmacology, Toxicology and Pharmaceutics
Roope Lasanen, Petro Julkunen, Olavi Airaksinen et al. · 2015 · Skin Research and Technology
BACKGROUND: Topical menthol gels are used in the treatment of various pain conditions. However, the effect of the menthol concentration to skin cooling or cooling sensation is not clear. We hypothesized that increasing menthol…
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Xue Zhou, Yang Xu, Jia Wang et al. · 2011 · PLoS ONE
BACKGROUND: Autism is a common, severe and highly heritable neurodevelopmental disorder in children, affecting up to 100 children per 10,000. The MET gene has been regarded as a promising candidate gene for this disorder because it is located within a replicated linkage interval, is involved in pathways affecting the development of the cerebral cortex and cerebellum in ways relevant to autism patients, and has shown significant association signals in previous studies. PRINCIPAL FINDINGS: Here, we present new ASD patient and control samples from Heilongjiang, China and use them in a case-contro
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Wei Li, Laura Germine, Samuel A. Mehr et al. · 2022 · Infant and Child Development
Widespread failures of replication and generalization are, ironically, a scientific triumph, in that they confirm the fundamental metascientific theory that underlies our field. Generalizable and replicable findings require testing large…
View details →Negative / Null Result ReportOpen accessAgricultural and Biological Sciences
Santiago López‐Miranda, Daniel Berdejo, Elisa Pagán et al. · 2020 · Journal of the Science of Food and Agriculture
Abstract BACKGROUND The antimicrobial activity of essential oils and their constituents has led to increasing interest in using them as natural preservative agents. However, their high sensitivity to light and oxygen, their volatility and…
View details →Negative / Null Result ReportOpen accessMedicine
Hwa Young Ahn, Hye Sook Min, Yohwan Yeo et al. · 2015 · The Journal of Clinical Endocrinology & Metabolism
CONTEXT: Previous studies on the extent to which radioactive iodine (RAI) therapy for thyroid cancer increases the risk of subsequently developing breast cancer have given conflicting results. OBJECTIVE: This study aimed to evaluate the…
View details →Negative / Null Result ReportOpen accessMedicine
Lily R. Aleksandrova, Yu Tian Wang, Anthony G. Phillips · 2017 · Chronic Stress
The prevailing hypothesis of ketamine's unique antidepressant effects implicates N-methyl-d-aspartate receptor (NMDAR) inhibition-dependent enhancement of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated transmission,…
View details →Negative / Null Result ReportMedicine
Lekshmi Santhosh, Snigdha Jain, Anna K. Brady et al. · 2017 · Annals of the American Thoracic Society
RATIONALE: It is important for attending physicians to know which behaviors influence learner perceptions. To date, two studies focusing on general medicine attending physicians have been published addressing internal medicine residents'…
View details →Negative / Null Result ReportOpen accessMathematics
Àngels Colomé · 2018 · Quarterly Journal of Experimental Psychology
Larger distance effects in high math-anxious individuals (HMA) performing comparison tasks have previously been interpreted as indicating less precise magnitude representation in this population. A recent study by Dietrich, Huber, Moeller, and Klein limited the effects of math anxiety to symbolic comparison, in which they found larger distance effects for HMA, despite equivalent size effects. However, the question of whether distance effects in symbolic comparison reflect the properties of the magnitude representation or decisional processes is currently under debate. This study was designed t
View details →Negative / Null Result ReportOpen accessBiochemistry, Genetics and Molecular Biology
Christos Mavrommatis, Daniel W. Belsky, Kejun Ying et al. · 2025 · Nature Communications
Epigenetic Clocks have been trained to predict chronological age, healthspan and lifespan. Such clocks are often analysed in relation to disease outcomes - typically using small datasets and a limited number of clocks. Here, we present a large-scale (n = 18,859), unbiased comparison of 14 widely used clocks as predictors of 174 incident disease outcomes and all-cause mortality over 10-years of follow up. Second- and third-generation clocks significantly outperform first-generation clocks, which have limited applications in disease settings. Of the 176 Bonferroni significant (P 1%. However, the
View details →Negative / Null Result ReportOpen accessMedicine
Harriet Lampe, Laura Tam, Aaron R. Hansen · 2024 · Frontiers in Pharmacology
Metastatic castrate resistant prostate cancer (mCRPC) continues to have poor survival rates due to limited treatment options. Bi-specific T cell engagers (BiTEs) are a promising class of novel immunotherapies with demonstrated success in haematological malignancies and melanoma. BiTEs developed for tumour associated antigens in prostate cancer have entered clinical testing. These trials have been hampered by high rates of treatment related adverse events, minimal or transient anti-tumour efficacy and generation of high titres of anti-drug antibodies. This paper aims to analyse the challenges f
View details →Negative / Null Result ReportOpen accessEnvironmental Science
Kyle Lesinger, Di Tian · 2025 · Nature Communications
Deep neural networks that learn from climate reanalysis data have produced skillful weather forecasts within ten days. However, it is still a great challenge for dynamic models to predict soil moisture, droughts, and other extreme events…
View details →Negative / Null Result ReportOpen accessBusiness, Management and Accounting
Tiasha Islam, Murugesh Arunachalum, Nirosha Hewa Wellalage et al. · 2025 · Business Strategy and the Environment
ABSTRACT This study examines the interplay between social media sentiment (SMS) and corporate reputation (CR) in shaping the relationship between corporate environmental performance (CEP) and corporate financial performance (CFP). Using a…
View details →Negative / Null Result ReportOpen accessPsychology
R. Chris Fraley, Jia Y. Chong, Kyle A. Baacke et al. · 2022 · Advances in Methods and Practices in Psychological Science
Scholars and institutions commonly use impact factors to evaluate the quality of empirical research. However, a number of findings published in journals with high impact factors have failed to replicate, suggesting that impact alone may…
View details →Negative / Null Result ReportOpen accessMedicine
Alejandro Borrego-Ruiz, Juan J. Borrego · 2024 · Nutrients
BACKGROUND/OBJECTIVES: Diet is one of the major determinants of the composition and function of the gut microbiome, and diverse studies have established directional connections between gut microbiome dysbiosis and skin dyshomeostasis. Furthermore, a significant link between the gut and certain skin-related disorders has been reported. This work reviews the mechanisms underlying the relationship between nutritional factors, gut microbiome, and certain skin diseases such as acne vulgaris, alopecia, and atopic dermatitis. In addition, it explores how the modulation of the gut microbiome and human
View details →Negative / Null Result ReportOpen accessMedicine
Catherine Gutierrez, Anthony S. Stein, Amir T. Fathi et al. · 2025 · American Journal of Hematology
Acute myeloid leukemia is a molecularly heterogenous disease caused by the rapid expansion and impaired differentiation of malignant myeloid progenitors. Overall, outcomes remain poor, and more than half of patients develop relapsed or…
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