Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study
Sergio Cleto; Camila Eleutério Rodrigues; Ceila María Sant’Ana Malaque; Jaques Sztajnbok; Antônio Carlos Seguro; Lúcia Andrade · 2016 · PLoS ONE
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
BACKGROUND: Leptospirosis is a health problem worldwide. Its most severe form is a classic model of sepsis, provoking acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI), with associated mortality that remains unacceptably high. We previously demonstrated that early initiation of sustained low-efficiency dialysis (SLED) followed by daily SLED significantly decreases mortality. However, the mode of clearance can also affect dialysis patient outcomes. Therefore, the objective of this study was to compare the effects of SLED with traditional (diffusive) clearance, via hemodia
Abstract by Sergio Cleto; Camila Eleutério Rodrigues; Ceila María Sant’Ana Malaque; Jaques Sztajnbok; Antônio Carlos Seguro; Lúcia Andrade, PLoS ONE (2016) — licensed CC BY 4.0.
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Metadata source: OpenAlex · DOI 10.1371/journal.pone.0160010