Decreased levels of interleukin-6 level in tears and clinical changes in subjects with moderate-to-severe infection corneal ulcers treated with platelet-rich fibrin lysate eye drops
Jehan Fauzi Rakhmandani; Indra Tri Mahayana; Felicia Widyaputri; Reny Setyowati; Agus Supartoto; Yohanes Widodo Wirohadidjojo; Suhardjo Pawiroranu · 2023 · Taiwan Journal of Ophthalmology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
PURPOSE: To assess the change of interleukin-6 (IL-6) levels in tears and ocular clinical parameters in corneal ulcer patients with moderate-to-severe infection after adjunctive therapy with platelet-rich fibrin (PRF) lysate-eyedrops compared with autologous serum eyedrops. MATERIALS AND METHODS: This study was a randomized double-blind controlled trial, which compared two groups of patients at Dr. Sardjito Hospital, Yogyakarta. A total of 42 patients (42 eyes) were divided into the control group (21 patients) and the intervention group (21 patients). All patients received antibacterial/antifu
Abstract by Jehan Fauzi Rakhmandani; Indra Tri Mahayana; Felicia Widyaputri; Reny Setyowati; Agus Supartoto; Yohanes Widodo Wirohadidjojo; Suhardjo Pawiroranu, Taiwan Journal of Ophthalmology (2023) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.4103/tjo.tjo-d-23-00023