Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Mohamed A. Mortada, Haidy E. Zidan, Noha A. Abdelsalam et al. · 2020 · Egyptian Rheumatology and Rehabilitation
Abstract Background Impaired deoxyribonucleic acid (DNA) repair may induce an autoimmune response in susceptible individuals. The association between DNA repair gene XRCC1 Arg399Gln gene polymorphism and susceptibility of systemic lupus erythematosus (SLE) is controversial. This study aimed to detect the association of XRCC1 Arg399Gln gene polymorphism with SLE and its clinical manifestations in the Egyptian population. Results A significant association was found between weight loss and genotype GG (P = 0.048); however, genotype AG was significantly associated with high serum creatinine and lo
View details →Negative / Null Result ReportOpen accessImmunologic diseases. Allergy
Hiroyuki Kawahara, Satoshi Hara, Noriko Iwaki et al. · 2025 · Immunological Medicine
TAFRO syndrome is a systemic inflammatory disorder of unknown etiology, and its diagnosis requires the exclusion of autoimmune diseases. A 42-year-old Japanese woman presented with TAFRO syndrome-like manifestations, but had undiagnosed limited-cutaneous systemic sclerosis preventing a definitive diagnosis of TAFRO syndrome. However, her clinical course and pathological findings, including renal glomerular microangiopathy, were consistent with TAFRO syndrome. We performed a systematic review of the literature to evaluate how autoimmunity affects the clinical characteristics of TAFRO syndrome/i
View details →Negative / Null Result ReportOpen accessMedicine
Amr Almaz Abdel-aziem, Amira Hussin Draz · 2013 · Medicine Science
The purpose of this study was to examine the effect of chronic ankle instability (CAI) on eccentric peak torque of the ankle musculature. The study included fifty participants divided into two groups; the first group consisted of twenty five subjects suffering from CAI, the second group consisted of twenty five subjects with no prior history of ankle injury as control group. Eccentric peak torque of invertors, evertors, plantar-flexors and dorsiflexors was recorded for each participant at angular velocities 30 and 90o/sec by using (Biodex Medical Systems, Inc, Shirley, NY, USA). Analysis of va
View details →Negative / Null Result ReportOpen accessMedicine (General)
A.G. Elsaid, N.M. Faheem · Brazilian Journal of Medical and Biological Research
Continuous industrial productivity and modern societies have resulted in excess artificial light. The altered circadian rhythm causes many diseases. During intrauterine life, the mother's maternal melatonin rhythm has a major role in influencing organ development. The aim of this study was to investigate the effect of maternal exposure to constant light on the structure and ultrastructure of neonatal skin. Twenty pregnant New Zealand rabbits were divided into two groups (n=10 each): control group (12-h light/dark) and constant light group (24-h light). Plasma maternal melatonin and corticoster
View details →Negative / Null Result ReportOpen accessOrthopedic surgery
Ahmet Salduz, Fatih Dikici, Önder Ismet Kılıçoğlu et al. · 2017 · Journal of Orthopaedic Surgery
Purpose: The aim of our study is to investigate the bone ongrowth of two different alternative surfaces and the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on osseointegration. Methods: Hips of 40 New Zealand white rabbits were operated bilaterally. Hydroxyapatite (HA)-coated titanium rods were implanted into the right femur, and grit-blasted titanium rods were implanted into the left femur. They were divided into three groups. At the end of 8 weeks, both femora of the rabbits were removed and investigated biomechanically and histologically. Results: HA-coated implants had a signif
View details →Negative / Null Result ReportOpen accessMedicine
XUE Bing, XI Hualei, YAO Lihong, XU Wanqiu, XU Xiaohang, LIN Song, PIAO Guiyan, WANG Xiumei · 2025 · 口腔疾病防治
Objective To investigate the effect of neurite outgrowth inhibitor extracellular peptide residues 1-40 (NEP1-40) combined with poly (lactic-co-glycolic acid) (PLGA) and gelatin electrospun fiber membrane on facial nerve repair in rats. Methods According to the principle of random grouping, 108 male SD rats were divided into four groups ( n = 27 in each group, approved by the ethics committee), namely, the sham group, control group, PLGA group, and NEP1-40 + PLGA group. A facial nerve fracture model was established for all of the groups except for the sham group. The control group received no f
View details →Negative / Null Result ReportOpen accessEcology
Mnqobi Mamba, Nicolas J. Fasel, Themb'alilahlwa A.M. Mahlaba et al. · 2019 · Global Ecology and Conservation
Conversion of native habitats into agricultural monocultures is a major cause of biodiversity loss favouring a small number of generalist species. Rodents can cause significant declines in crop yield, hence understanding the factors affecting their population dynamics is of importance to the agricultural sector. Sugarcane plantations in African savannas harbour a low diversity of small mammals, with a single genus (Mastomys spp.) often dominating the community. Our study investigated the factors that shape the composition of the small mammal community and the life-history traits of the dominan
View details →Negative / Null Result ReportOpen accessAnesthesiology
Hasanul Arifin, Heru Kurniawan · 2016 · Jurnal Anestesi Perioperatif
Serum creatinine has many limitations when being used to diagnose acute kidney injury (AKI), especially in the scope of intensive care unit due to its low sensitivity to depict the kidney dysfunctional level of critically-ill patients. Out of numerous new available biological markers, four biological markers are widely used all over the world to detect AKI, e.g. neutrophil gelatinase-associated lipocalin (NGAL), cystatin C, KIM-1, and interleukin-18. The purpose of this study was to determine the sensitivity and specificity of serum cystatin C and creatinine in establishing the diagnosis of ac
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Xiaotong Xu, Jinglan Jin, Yuwei Liu et al. · 2023 · BMC Gastroenterology
Abstract Background and aims To investigate the usefulness of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), protein C (PC), and thromboelastography (TEG) to serve as a predictor of portal vein thrombosis (PVT) in patients with liver cirrhosis. Additionally, we examined the clinical significance of the above indicators in terms of disease progression. Methods A total of 123 patients with liver cirrhosis were recruited from May 2021 to December 2021, according to the imaging findings. They were divided into the PVT group (n = 52) and the non-PVT group (n = 71). Furthermore, patients
View details →Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Dong-Yun Kim, Eonju Park, Chan Yeong Heo et al. · 2021 · Breast
Purpose: This study investigated whether hypofractionated adjuvant radiotherapy (RT) increased breast-related complication(s) compared to conventional fractionated RT in reconstructed breast cancer patients. Methods: We conducted a retrospective review including 349 breast cancer patients who underwent immediate breast reconstruction following mastectomy or breast-conserving surgery (BCS) between 2009 and 2018 at two institutions. All patients were treated with adjuvant RT via either a conventional fractionated or hypofractionated regimen. We defined a major breast complication as a breast-rel
View details →Negative / Null Result ReportOpen accessEconomics as a science
gholamhossain khorshidi, Arash Naghash, milad mohamadian · 2014 · پژوهشهای اقتصادی
Nowadays, the issue of service quality for service-provider organizations specifically banks is of considerable importance. The service-provider organizations (specifically governmental banks) are aware from the necessity of getting satisfaction of customer and assessing quality of services. In this research, we evaluate and analyze the gap of expected and current service quality. In fact, the gap between customer´s expectations of bank services and customers perceptions is assessed based on the hierarchical service quality model (HSQM), which has been introduced by Brady and Cronin in 2001. T
View details →Negative / Null Result ReportOpen accessMedicine
Hulya Colak, Ismail Sert, Yusuf Kurtulmus et al. · 2014 · Saudi Journal of Kidney Diseases and Transplantation
The objective of the study is to evaluate the relationship between serum testos-terone levels and cardiovascular risk factors (CVRF) in patients after kidney transplantation and with chronic kidney disease (CKD). Seventy-five male patients, aged between 18 and 68 years, who had kidney transplantation at least six months earlier, were enrolled into the study. Only renal transplant recipients and CKD patients with a creatinine level of 0.05). Serum testosterone levels were independent risk factors affecting IVC collapse index, systolic BP and LA. m-TORi and CNIs drugs might have no negative effe
View details →Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Ha-yeong Baek, Seung-yoon Han, Il-kyu Ahn et al. · 2026 · Physical Therapy Korea
Background: Hip abductor muscles play a critical role in stabilizing the pelvis during functional activities. A decline in hip abductor strength is associated with impaired balance and an increased risk of falls, particularly in elderly females who experience physiological changes and age-related muscle loss. Although limb dominance has been proposed to influence lower extremity muscle strength in young adults, no studies have yet examined differences in hip abductor strength between the dominant and non-dominant limbs in elderly females. Furthermore, the relationship between hip abductor stre
View details →Negative / Null Result ReportOpen accessTheory and practice of education
Riza Salar, Umit Turgut · 2021 · Science Education International
The learning characteristics of each student are different. Differentiated instruction considers individual differences, as such guides the learning journey rather than seeing these differences as a challenge. The purpose of this research was to compare the effects of differentiated instruction and 5E learning cycle in physics classes on the students' academic achievement and self-efficacy. We used the matching - pre-test/post-test - control group design to address the research questions. We conducted the study in three different schools, performed three experiments, and had three control grou
View details →Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
杨江胜，朱祖福，高志强，陆强彬，周国庆，方琪 · 2018 · Zhongguo cuzhong zazhi
目的 探讨高龄轻型缺血性卒中3 h内行阿替普酶静脉溶栓治疗的疗效及安全性。 方法 将我院2015年10月-2017年10月连续收治入院的发病3 h内48例高龄急性轻型缺血性卒中患者 随机分为阿替普酶静脉溶栓组24例和未溶栓组24例。比较两组患者入院时的一般情况，基线美国 国立卫生研究院卒中量表（National Institutes of Health Stroke Scale，NHISS）评分，治疗24 h后颅内出 血转化率，治疗后90 d改良Rankin量表（modified Rankin Scale，mRS）评分及90 d病死率。 结果 阿替普酶静脉溶栓组和未溶栓组患者一般临床资料、基线NIHSS评分比较，差异无统计学意 义。阿替普酶静脉溶栓组和未溶栓组治疗24 h后颅内出血转化率分别为4.17%和0（P =1.000），两组 90 d病死率均为4.17%（P =1.000），阿替普酶静脉溶栓组及未溶栓组90 d mRS评分为0～2分的比率 分别为83.33%和54.17%（P =0.029）。 结论 早期阿替普酶静脉溶栓治疗高龄急性轻型缺血性卒中不增加急性期颅内出血转化的风险， 可以改善高龄轻型缺血性卒中患者预后，不增加病死率。 Abstract: Objective To investigate the efficacy and safety of alteplase i
View details →Negative / Null Result ReportOpen accessMedicine
Zeyi Deng, Takayuki Uehara, Hiroyuki Maeda et al. · 2014 · PLoS ONE
To investigate the prevalence, genotypes, and prognostic values of Epstein-Barr virus (EBV) and human papillomavirus (HPV) infections in Japanese patients with different types of head and neck cancer (HNC).HPV and EBV DNA, EBV genotypes and LMP-1 variants, and HPV mRNA expression were detected by PCR from fresh-frozen HNC samples. HPV genotypes were determined by direct sequencing, and EBV encoded RNA (EBER) was examined by in situ hybridization.Of the 209 HNC patients, 63 (30.1%) had HPV infection, and HPV-16 was the most common subtype (86.9%). HPV E6/E7 mRNA expression was found in 23 of 60
View details →Replication Failure
· 2019 · Journal of Gynecology & Reproductive Medicine
Karyotyping is a technique to examine the chromosomes-abnormality or structural defects. Karyotyping can be used to detect a variety of genetic disorders. For example, a woman who has premature ovarian failure may have a chromosomal defect…
View details →Negative / Null Result ReportOpen accessMedicine
Fatemeh Samiei Siboni, Zainab Alimoradi, Tahereh Sadegi · 2013 · مجله دانشگاه علوم پزشکی بیرجند
Background and Aim: Life style can cause stress and anxiety and consequently, hypertension. Regarding nurses' influencial role in implementing educational programs to increase patients’ self-control, the present research was designed to study the impact of a lifestyle promoting educational programs on controlling stress, anxiety, depression, and hypertewnsion in Qazvin Mino area in 2010. Materials and Methods: after the present study was a pre/post semi-experimental one conducted on 55 hypertensives. Living in Qazvin Minodar region. DAS (Depression, Anxiety, Stress)-21 general questionnaire an
View details →Negative / Null Result ReportOpen accessMedicine (General)
Zhui-Feng Guo, Fan Yang, Xu-Wei Lu et al. · 2021 · Journal of International Medical Research
Objective To explore the significance of the prostate central gland to total gland volume ratio (PVc/PV) in the diagnosis of prostate cancer (PCa) in patients with prostate specific antigen (PSA) levels in the grey zone (4–10 ng/ml). Methods This retrospective study enrolled patients that had undergone prostate biopsy. The volume of the prostate and the central prostate gland were measured. The differences in PSA, the ratio of free to total PSA (f/tPSA), PSA density (PSAD) and PVc/PV between the PCa and non-PCa groups were compared. Receiver operating characteristic curve analysis for PCa and
View details →Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Mohamed Abdelkhalek, Ahmed Setit, Francesco Bianco et al. · 2018 · Annals of Coloproctology
Purpose Revolutions have occurred over the last 3 decades in the management of patients with colorectal cancer. Most advances were in rectal cancer surgery, especially after the introduction of the total mesorectal excision (TME) by Heald. However, no parallel advances regarding colon cancer surgeries have occurred. In 2009, Hohenberger introduced a new concept trying to translate the survival advantages of TME to patients with colon cancer. This relatively new concept of a complete mesocolic excision (CME) with central vascular ligation (CVL) in the management of patients with colon cancer re
View details →Negative / Null Result ReportOpen accessAnimal culture
RAVIKANTH JETTY, S SREEDHAR, CH VENKATA SESHAIAH2 et al. · 2025 · Indian Journal of Animal Sciences
The present research was conducted to study the effect of fan and foggers on Temperature Humidity Index (THI) and physiological responses in Nellore brown sheep during summer. Twenty ewes of age 3-5 years from sheep unit of Livestock Farm Complex of NTR college of Veterinary Sciences, Gannavaram were divided into 2 groups of each 10 ewes each in a completely randomized design on the basis of body weight. The animals in the group-I were considered as control whereas the animals in the group-II were equipped with fan and foggers for modification of microclimate in the shed. Data on temperature-h
View details →Negative / Null Result ReportOpen accessScience (General)
Chong Teng, Ling Li, Dan Su et al. · 2024 · Heliyon
Objective: To detect levofloxacin (LFX) and moxifloxacin (MFX) resistance among rifampicin-resistant tuberculosis (RR-TB) isolates, and predict the resistance level based on specific mutations in gyrA and gyrB genes. Methods: A total of 686 RR-TB isolates were collected from Chinese Drug Resistance Surveillance Program from 2013 to 2020. The minimum inhibitory concentrations (MICs) of 12 anti-TB drugs were acquired using the broth microdilution method, followed by whole genome sequencing (WGS) analysis. Results: Among the 686 RR isolates, the most prevalent resistance was to isoniazid (80.5 %)
View details →Negative / Null Result ReportOpen accessManagement. Industrial management
Majid Aligholizadeh, Mohammad Akbari, Fatemeh Zandian et al. · 2014 · مطالعات مدیریت راهبردی
The aim of Paper is to analyze and evaluate the performance of management in Tehran academic public libraries based on the model of EFQM that tries to identify the weak points and strong points of the management, plan for the improvement of strong points and resolve the weak points to get to a more competent and desirable situation in the society so that they can be able to improve their services and satisfy the needs of their members and customers more than ever. The methodology used to conduct this research is a survey and to collect the data a 72 item questionnaire of European Foundation fo
View details →Negative / Null Result ReportOpen accessDentistry
Nsar Muhyaddin Aziz · 2022 · Erbil Dental Journal
Background and objectives: Gutta percha solvents like chloroform and orange oil have different effects on physio-chemical properties like the microhardness of root dentine. Aim: Effects of sesame oil on the micro hardness of root dentin after using chloroform and orange oil as guttapercha solvents. Methods: Twenty three extracted single rooted both upper and lower premolars were used crown separated from the root from the cement enamel junction ,remaining roots longitudinally sectioned from buccolingual direction each piece of roots mounted in cold cure acrylic resin and dentin surface of the
View details →Negative / Null Result ReportOpen accessAgriculture
S.H. Hoseinifar email ; A.R. Mirvaghefi; B. Mojazi Amiri; H.A. Khoshbavar Rostami; M. Poor Amini; K. Darvish Bastami · 2011 · Majallah-i ̒Ilmī-i Shīlāt-i Īrān
The probiotic effects of inactive yeast, Saccharomyces cerevisiae var. ellipsoideus was studied on growth performance, survival and intestinal microbiota of beluga juveniles (Huso huso). The study was done in complete randomize design that included feeding of beluga juveniles with diets supplemented with 0 (control), 1, 2 and 5% yeast (4 treatments with 3 replicates). Beluga juveniles (11.40±0.56g) were randomly allocated in 12 oval tanks at a density of 35 fish per tank and triplicate group were fed with experimental diets. At the end of the trial, growth factors (final weight, weight gain,
View details →Negative / Null Result ReportOpen accessMedicine (General)
Lee J, Jo D, Song S et al. · 2020 · Journal of Pain Research
Jongseok Lee,1 Daehyun Jo,2 Shinmi Song,1 Dahee Park,1 Dohyeong Kim,1 Jinyoung Oh1 1Department of Anesthesiology and Pain Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Pain Center, Pohang Wooridul Hospital, Pohang-si, Gyeongsangbuk-do, Republic of KoreaCorrespondence: Jinyoung OhDepartment of Anesthesiology and Pain Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-Ro, Gangnan-Gu, Seoul, Republic of KoreaTel +82-2-2019-3600Fax +82-2-2019-4833Email sgcms3@gmail.comPurpose: Dispersion of contrast media
View details →Negative / Null Result ReportOpen accessMedicine
Yu-Hsuan Wu, Yi-Huei Chen, Ming-Hong Chang et al. · 2018 · PLoS ONE
To evaluate the association between Parkinson's disease (PD) prognosis and the patient's onset of depression.A total of 353 patients with newly-diagnosed PD and a history of depression were enrolled. On the basis of the onset of depression before or after PD diagnosis, we divided participants into PD patients with pre- or post-diagnostic depression. Cox's regression analysis was used to detect risks between the onset of depression and outcomes (including death, accidental injury, dementia, and aspiration pneumonia). The association between the onset of depression and levodopa equivalent dosage
View details →Negative / Null Result ReportOpen accessMedicine
WANG Yibo, HAN Yingdong, XIE Tiange, WU Juan, DI Hong, ZHANG Yun, ZENG Xuejun · 2025 · Jichu yixue yu linchuang
Objective To characterize the clinical features of the group of gout patients to facilitate earlier identification, and optimize the diagnosis and treatment of the condition. Methods The retrospective study analyzed 24 gout patients with shoulder joint(s) involved and consulted by physicians of Peking Union Medical College Hospital from March 2021 to April 2025, while 70 outpatient gout patients matched by clinical course duration and sex were enrolled as control group. Clinical data including medical history, laboratory tests, therapeutic interventions. Prognosis was systematically collected
View details →Negative / Null Result ReportOpen accessSurgery
Leonardo de Castro Durães, Eliana Ferreira Ribeiro Durães, Pedro Felipe Silva de Freitas et al. · 2013 · Acta Cirúrgica Brasileira
PURPOSE: To evaluate the feasibility and safety of a new technique for laparoscopic segmental colectomy and primary anastomosis in the left colon of rats. METHODS: Thirty rats were randomly assigned to three groups of ten animals each. All animals underwent segmental resection of the left colon and end-to-end anastomosis. In Group I, the animals underwent laparoscopic surgery with carbon dioxide pneumoperitoneum at a pressure of 5 mmHg. In Group II, the animals underwent pneumoperitoneum with carbon dioxide at a pressure of 12 mmHg. In Group III, the control group, the animals underwent open s
View details →Negative / Null Result ReportOpen accessInternal medicine
Tutik Kusmiati, Ni Made Mertaniasih, Johanes Nugroho Eko Putranto et al. · 2022 · Acta Medica Indonesiana
Background: Drug-resistant tuberculosis (DR-TB) is a global health concern. QTc prolongation is a serious adverse effect in DR-TB patients receiving a shorter regimen. This study aimed to evaluate the correlation of moxifloxacin concentration, CRP, and inflammatory cytokines with QTc interval in DR-TB patients treated with a shorter regimen. Methods: This study was performed in 2 groups of rifampicin-resistant (RR-TB) patients receiving shorter regimens. Correlation for all variables was analyzed. Results: CRP, IL-1β, and QTc baseline showed significant differences between 45 RR-TB patients on
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