Gene XRCC1Arg399Gln polymorphism and its genotype variations: clinical associations in Egyptian systemic lupus erythematosus patients
Mohamed A. Mortada; Haidy E. Zidan; Noha A. Abdelsalam; Mirvat A. Eltoukhy · 2020 · Egyptian Rheumatology and Rehabilitation
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Abstract Background Impaired deoxyribonucleic acid (DNA) repair may induce an autoimmune response in susceptible individuals. The association between DNA repair gene XRCC1 Arg399Gln gene polymorphism and susceptibility of systemic lupus erythematosus (SLE) is controversial. This study aimed to detect the association of XRCC1 Arg399Gln gene polymorphism with SLE and its clinical manifestations in the Egyptian population. Results A significant association was found between weight loss and genotype GG (P = 0.048); however, genotype AG was significantly associated with high serum creatinine and lo
Abstract by Mohamed A. Mortada; Haidy E. Zidan; Noha A. Abdelsalam; Mirvat A. Eltoukhy, Egyptian Rheumatology and Rehabilitation (2020) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1186/s43166-020-00009-2