21,770 real negative results, null findings, and replication failures. Search the index →
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record compiled from open scholarly databases; the abstract is shown in full only where the paper is openly licensed, otherwise a short excerpt under fair use. Classifications are automated and approximate.
Kasanmonadi RYN, Kamperman AM, Koch BCP et al. · 2026 · Journal of clinical psychopharmacology
Purpose/background Although combined plasma levels of imipramine and its metabolite desipramine are routinely assessed during therapeutic drug monitoring (TDM) of imipramine treatment, individual plasma levels are often overlooked.…
View details →Altan E, Küçüktağ Z, Arslankoz S et al. · 2026 · European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
OBJECTIVE: Sinonasal inverted papillomas (IPs) and nasal polyps (NPs) represent distinct benign lesions with different biological behaviors. P-glycoprotein (P-gp), a multidrug resistance transporter, has been implicated in inflammatory and…
View details →Kano T, Kawaguchi Y, Nishioka Y et al. · 2026 · Surgery today
PURPOSE: To address our hypothesis that increased surgical costs for robotic liver resection would be compensated by reduced postoperative care expenses, we compared the economic outcomes of robotic, laparoscopic, and open liver resection…
View details →Kaya G, Oskay PÖ, Mert NK et al. · 2026 · BMC infectious diseases
Background Coronavirus disease 2019 (COVID-19), first identified in Wuhan, China, in December 2019, rapidly evolved into a global pandemic with substantial morbidity and mortality. Severe COVID-19 cases, particularly those with pneumonia…
View details →Üstün Y, Yanık S, Uçar F et al. · 2026 · BMC gastroenterology
Background Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic disorders with relapsing and remitting disease courses. Several clinical indicators and biomarkers have been evaluated…
View details →Miyauchi K, Narita T, Morishita S et al. · 2026 · Preprint
Abstract Background Whether initial dose reduction of apalutamide compromises clinical outcomes in patients with androgen pathway modulation–naïve metastatic prostate cancer remains uncertain. In routine practice, reduced dosing is often…
View details →Oloruntoba AI, Rodrigues M · 2026 · Journal of cosmetic dermatology
Background Fractional CO 2 laser is an effective treatment for skin rejuvenation, although pigmentary complications remain a clinical consideration. Newer generation fractional CO 2 laser systems include pulse modes such as HighPulse (HP),…
View details →Çarikçi F, Girgin BA, Harmanci NF et al. · 2026 · Child abuse & neglect
Aim To examine and compare the proficiency of pediatric physicians and nurses in recognizing the signs of and risk factors for child maltreatment, as well as to determine the relationship between this proficiency and their reporting…
View details →Inokuchi T, Hiraoka S, Oshima N et al. · 2026 · Gerontology
Introduction We previously reported the findings of a multicenter retrospective cohort study investigating the efficacy of oral tacrolimus induction therapy in patients with ulcerative colitis (UC). In this subanalysis, we specifically…
View details →Nishino S, Asada Y, Nishino C et al. · 2026 · Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
Background Isolated atrial amyloidosis is characterized by atrial natriuretic peptide- (ANP-) amyloid deposition confined to the atria and has been primarily linked to atrial fibrillation. However, its relationship with atrial mechanical…
View details →Hegde P, Acharya SR, Mayya A et al. · 2026 · International journal of dentistry
Background White spot lesions (WSLs) represent the earliest clinical manifestations of enamel demineralization. Resin infiltration (RI) is a minimally invasive method used to mask WSLs for esthetic improvement; however, infiltrated enamel…
View details →Li H · 2026 · Archives of sexual behavior
Previous research has shown that people tend to associate higher vertical spatial positions with male and lower positions with female. In this study, we document an understudied vertical representation of gender within Azhaliism, a…
View details →Fentahun M · 2026 · Scientific reports
Traditionally fermented beverages are potential sources of industrially relevant microorganisms. Among alternative energy sources, biofuels have gained increasing attention as replacements for fossil fuels. This study aimed to investigate…
View details →Lee J, Hwang HS, Li Y et al. · 2026 · Archives of insect biochemistry and physiology
Nesidiocoris tenuis is an important natural enemy widely used for the biological control of small pests in vegetable crop systems. Its successful implementation in commercial programs depends on reliable and cost-effective mass rearing,…
View details →Park SJ, Kim JY, Yun S et al. · 2026 · Journal of clinical medicine
Background/Objectives : Trauma triggers complex early immune responses. However, the relationship among trauma severity, changes in immune cell survival, and circulating inflammatory mediators remains unclear. This study compared early…
View details →Gülegen HÇ, Temelli G, Ucuz İ et al. · 2026 · Epilepsy & behavior : E&B
Objective Cognitive and behavioral difficulties in pediatric epilepsy extend beyond seizures. Although executive dysfunction is well recognized, Cognitive Disengagement Syndrome (CDS) remains understudied. We examined CDS-related symptoms…
View details →Sasaki M, Aoki T, Uchibori M et al. · 2026 · Oral diseases
Objective Many countries have implemented health technology assessment of their public medical insurance programs owing to rising social security costs from ageing populations and expensive emerging medical technologies. Clarifying factors…
View details →Thomas RM, Nayak R, Madi M et al. · 2026 · BMC oral health
Remaining Root Dentin Thickness (RRDT) after root canal instrumentation is an important parameter to be assessed with newer file systems. This study aimed to evaluate the root dentin thickness following instrumentation of primary molar…
View details →Zapata KA, McGinley JJ, Sucato DJ et al. · 2026 · Spine deformity
Purpose To evaluate the effectiveness of nighttime brace treatment in boys with adolescent idiopathic scoliosis (AIS) compared to girls according to brace adherence and curve progression. Methods Children with predominantly…
View details →Bleckwedel J, Nieva RE, González V et al. · 2026 · Preprint
Soybean ( Glycine max [L.] Merr.) productivity is frequently compromised by soil-borne pathogens. Macrophomina phaseolina (Mp), the causal agent of charcoal rot, can produce important soybean yield losses especially when hot and dry…
View details →Hayashi K, Yoshida M, Hayashi S et al. · 2026 · Japanese journal of ophthalmology
Purpose To compare visual function between pseudophakic eyes with enhanced monofocal intraocular lenses (IOLs) and phakic eyes with clear lenses among patients in their 50s, 60s, and 70s. Study design Prospective comparative study. Methods…
View details →Strumpf ZB, Balijepalli S, Galchenko P et al. · 2026 · Respiratory medicine
Purpose Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is essential for mediastinal staging in non-small cell lung cancer (NSCLC), yet uniform lymph node (LN) size criteria for sampling remain unvalidated.…
View details →Chapron L, Bellot L, Mallet Y et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose To assess the diagnostic value of tomographic signs on OCT and OCT-A, particularly paracentral acute middle maculopathy (PAMM), in predicting temporal artery biopsy (TAB) positivity in suspected giant cell arteritis (GCA),…
View details →Shehu E, Arora K · 2026 · Health services research
Objective To examine whether different caregiving arrangements influence hospitalization risk and frequency among older adults with functional limitations. Study setting and design This longitudinal study used linear probability and…
View details →Zhang Y, Yu W, Shen W · 2026 · Medicine
This study aimed to explore the effects of 3 immediate reconstruction methods - prosthesis implantation, latissimus dorsi flap (LDF), or their combination - on postoperative outcomes following breast cancer (BC) surgery. A retrospective,…
View details →Tomalka A, Weidner S, Rode C et al. · 2026 · Experimental physiology
Eccentric muscle contractions are essential for locomotion and daily activities. Force during these contractions depends on both cross-bridge (XB) and non-cross-bridge (non-XB) elements, including titin, with contributions varying by fibre…
View details →Qi Z, Li W, Li Z et al. · 2026 · Preprint
Abstract Background Female genital cosmetic surgery (FGCS) has gained increasing popularity worldwide, with high reported satisfaction rates. However, dynamic postoperative changes may lead to patient anxiety and misinterpretation during…
View details →Ismaile S, Alhosban F, Shajrawi A et al. · 2026 · Preprint
Abstract Background Preparing undergraduate nurses for high-acuity practice requires educational approaches that allow safe rehearsal of complex clinical situations, yet evidence from routine programme delivery remains mixed when immersive…
View details →Dubowitz H, Belanger R, Magder L et al. · 2026 · Academic pediatrics
Hypothesis A Maintenance of Certification-4 activity (MOC) will help primary care practices implement the Safe Environment for Every Kid (SEEK) approach to prevent child maltreatment more effectively than simpler independent online…
View details →Chow JW, Yablon SA, Stokic DS · 2026 · NeuroRehabilitation
BackgroundAlthough several studies have examined gait changes associated with continuous intrathecal baclofen (CITB) infusion for spasticity in ambulatory patients with acquired brain injury (ABI), none has included a control…
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